$23.95 $0.53 per serving
Product analysis
Choline 500 mg supplies choline for normal liver cell function and fat transport, with the clearest benefit when intake is inadequate.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality65
Choline bitartrate is clearly identified and has a reasonable form comparison. It does not establish the same effects as other choline preparations.
Ingredient Transparency100
Amounts and forms are clearly identified. That makes the serving and ingredient choices easier to compare.
Value For Money50
The declared active content sits around the middle of the price comparison. Cost alone gives no clear reason to favor it over comparable alternatives.
Customer Satisfaction71
Customer ratings are favorable, but come from a small review pool. Reviews describe satisfaction without establishing effectiveness or safety.
Product Focus83
The clearest role is nutritional support for normal liver function. Its role in a brain messenger does not establish improved memory or sharper focus in adequately nourished adults.
- Format
Capsule - Container
- 90 Capsule(s)
- Per serving
- $0.53
- Customer rating
- 4.7 · 87 ratings
Goals
Impact
Highest effect
Choline · 500 mg
Choline helps the liver maintain cell integrity and export fat. Its clearest relevance is nutritional: restoring choline after depletion can reverse related liver dysfunction. The declared 500 mg per serving meets the saved amount comparison, but it does not establish extra toxin clearance when nutrient intake is adequate.
How this product is rated for Liver & Detox
Ingredient fit96
Declared choline provides a nutritional liver-function connection.
Goal fit
Declared choline provides a nutritional liver-function connection.
Dose adequacy
Choline meets the saved amount comparison; additional intake does not establish additional benefit.
Pathways59
Liver cell integrity and fat export is the main route in the saved findings.
Depth
Liver cell integrity and fat export is the main route in the saved findings.
Breadth
One route reaches substantial coverage; other routes are limited.
Evidence86
Choline depletion and repletion support a nutritional liver role, rather than extra toxin clearance.
Evidence strength
Choline depletion and repletion support a nutritional liver role, rather than extra toxin clearance.
Studied preparation
The declared choline amount is recognized directly, without converting carrier or phospholipid mass.
Formulation logic100
No required partner is missing and no configured ingredient conflict was found.
Partner coverage
The included ingredients work independently or have their required partner.
Conflicts
No configured ingredient conflict was found.
Effective doses
All included ingredients meet the saved minimum amount comparison; this does not establish a clinically effective toxin-clearance dose.
Impact
Highest effect
Choline · 500 mg
Choline supplies material used to make acetylcholine, a messenger involved in memory and attention. That normal role does not establish improved memory from supplemental choline: acute choline-bitartrate experiments in healthy young adults were unsuccessful. The declared 500 mg serving supports a clear amount comparison, but evidence for citicoline or Alpha-GPC cannot be transferred to generic choline.
How this product is rated for Cognitive Support
Ingredient fit96
The relevant ingredients keep the formula focused on cognition, though its uses extend across other goals. Declared amounts receive full recognition in the saved comparison; that does not establish benefit beyond the ingredient’s specific evidence.
Goal fit
The relevant ingredients keep the formula focused on cognition, though its uses extend across other goals.
Dose adequacy
Declared amounts receive full recognition in the saved comparison; that does not establish benefit beyond the ingredient’s specific evidence.
Pathways59
The strongest represented mechanism is acetylcholine signalling, within the limits of the relevant ingredients’ evidence. Support is concentrated in one mechanism rather than spread widely across memory, attention and related functions.
Depth
The strongest represented mechanism is acetylcholine signalling, within the limits of the relevant ingredients’ evidence.
Breadth
Support is concentrated in one mechanism rather than spread widely across memory, attention and related functions.
Evidence89
Vitamin B4 (Choline) leads the saved evidence finding, while its population and outcome limitations still apply. The saved finding accepts the relevant preparations for comparison; this does not remove limitations in the cognitive evidence.
Evidence strength
Vitamin B4 (Choline) leads the saved evidence finding, while its population and outcome limitations still apply.
Studied preparation
The saved finding accepts the relevant preparations for comparison; this does not remove limitations in the cognitive evidence.
Formulation logic100
No required ingredient partner is missing from the saved findings. No configured ingredient conflict is identified in the supplied findings. The included ingredients pass the minimum amount comparison, which is not proof that each improves cognition.
Partner coverage
No required ingredient partner is missing from the saved findings.
Conflicts
No configured ingredient conflict is identified in the supplied findings.
Effective doses
The included ingredients pass the minimum amount comparison, which is not proof that each improves cognition.
Impact
High effect
Choline · 500 mg
Choline is a nutrient and acetylcholine precursor, but precursor status alone does not establish sharper focus. A healthy-adult choline-bitartrate trial did not improve acute memory, so the declared amount should not be interpreted as proven acute concentration enhancement.
How this product is rated for Mental Focus
Ingredient fit96
The saved finding includes vitamin b4 (choline) among its relevant ingredients. The 500 mg serving reaches the saved amount comparison, without establishing clinical effectiveness.
Goal fit
Vitamin B4 (Choline) is the main ingredient in the saved focus finding.
Dose adequacy
The 500 mg serving reaches the saved amount comparison, without establishing clinical effectiveness.
Pathways60
The strongest saved connection is cholinergic signalling. One pathway reaches the configured coverage threshold.
Depth
The strongest saved connection is cholinergic signalling.
Breadth
One pathway reaches the configured coverage threshold.
Evidence74
Vitamin B4 (Choline) leads the saved evidence finding. Preparation, population and outcome limits remain relevant to the practical benefit.
Evidence strength
Vitamin B4 (Choline) leads the saved evidence finding, while the supplied scientific context limits claims of acute focus enhancement.
Studied preparation
The saved finding recognizes the counted preparations; this does not establish a special form or delivery advantage.
Formulation logic100
The counted ingredients work alone or have the partner required by the configuration. No configured ingredient conflict was found.
Partner coverage
The counted ingredients work alone or have the partner required by the configuration.
Conflicts
No configured ingredient conflict was found.
Effective doses
All counted ingredients pass the configured amount threshold; it is not a proven effective dose.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Choline (Choline Bitartrate) | 500 mg |
Choline (Choline Bitartrate) · 500 mg OverallScore81
A serving provides 500 mg of choline from choline bitartrate, a standard form. The whole-product price works out to about $0.11 per 100 mg of choline, a middle-range cost on this basis.
How this ingredient is rated
Active Ingredient Quality & Bioavailability77
Choline bitartrate is a standard form. The stored ingredient information records no flagged additives or flow agents.
Choline Form Efficacy & Bioavailability
Choline bitartrate is a standard form for systemic use, evaluated below Alpha-GPC and citicoline for cognitive use.
Formula Purity & Excipient Quality
The stored ingredient information records no flagged additives or flow agents.
Dose, Safety & Label Transparency100
The label states 500 mg of choline per serving and names choline bitartrate as the source.
Choline Dose by Declared Basis
The serving supplies 500 mg of choline.
Elemental Yield Transparency
The label gives both the choline amount and its source.
Value50
The whole-product price is about $0.11 per 100 mg of declared choline, a middle-range cost on this basis.
Price per 100 mg of Declared Choline Basis
The whole-product price is about $0.11 per 100 mg of declared choline, a middle-range cost on this basis.
Alternative products
Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
- Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
- Choline intake during pregnancy and child cognition at age 7 years.
- Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
- Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
- Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
- Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
- Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
- Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
- 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
- Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.
- The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.
- Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
- Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
- Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.