Choline 350 mg

Choline 350 mg

Solgar4.8 (1,250 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals

Product analysis

84 out of 100

Choline 350 mg offers an affordable way to fill a choline gap and support normal liver function. Its nutrient role does not establish sharper memory or faster toxin removal when intake is adequate.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality65

Choline is clearly identified as choline bitartrate. The form does not establish a special memory or attention advantage.

Ingredient Transparency100

The choline amount and form are stated. That makes the serving straightforward to compare.

Value For Money100

Choline offers favorable value for the amount provided. The simple formula keeps the purchase focused on that nutrient.

Customer Satisfaction84

Customer feedback is very positive across a large number of ratings. That gives a broad view of satisfaction without proving memory benefits.

Product Focus78

The clearest purpose is nutritional support when choline intake is low. Brain-signaling roles do not establish immediate focus or memory improvements with adequate intake.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.12
Customer rating
4.8 · 1,250 ratings
Report analysis

Goals

Liver & Detox
Impact
High effect
B+ Ingredient FitD PathwaysA- EvidenceA+ Formulation Logic
Choline · 350 mg

Choline supports normal liver function when low intake is corrected, a nutritional role rather than evidence of extra toxin removal. The 350 mg declared choline per serving contributes toward the supplied 550 mg nutrient-adequacy comparison, rather than a proven detoxification dose. The evidence concerns reversing dysfunction during depletion and repletion; it does not establish improved toxin clearance when intake is already adequate.

How this product is rated for Liver & Detox

Ingredient fit84

choline provides the main connection. The amounts provide only a partial match to the reference comparisons.
Goal fit
choline supplies a goal-related connection within a formula also associated with other health goals.
Dose adequacy
The declared choline amount contributes toward nutrient adequacy; it is below the supplied 550 mg reference and is not a proven detox dose.

Pathways47

The strongest mapped connection concerns liver-cell function; the relevant nutritional or disease-specific evidence does not establish routine toxin clearance. The coverage is concentrated in one area, without broad evidence for toxin removal.
Depth
The strongest mapped connection concerns liver-cell function; the relevant nutritional or disease-specific evidence does not establish routine toxin clearance.
Breadth
The coverage is concentrated in one area, without broad evidence for toxin removal.

Evidence86

Choline evidence supports a nutritional liver-function role during depletion and repletion, rather than extra toxin clearance.
Evidence strength
Choline evidence supports a nutritional liver-function role during depletion and repletion, rather than extra toxin clearance.
Studied preparation
The included ingredient has a preparation match in the saved comparison, which does not establish equivalent clinical toxin-clearance outcomes.

Formulation logic100

No missing required partner or configured conflict was identified. The included ingredients meet the minimum exposure comparison.
Partner coverage
No missing required partner was identified; combining these ingredients does not establish an extra detoxification benefit.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The included ingredients meet the minimum exposure comparison, which does not establish a clinically effective detoxification dose.
Study evidence
Choline Supportive 6 studies
Mental Focus
Impact
High effect
B+ Ingredient FitD PathwaysB- EvidenceA+ Formulation Logic
Choline · 350 mg

Choline supplies material for acetylcholine, a chemical involved in nerve signalling. This nutritional role does not establish better immediate focus when intake is adequate, and the supplied choline bitartrate findings did not show acute memory improvement. The saved findings recognize its amount and cholinergic connection, but neither establishes a dependable attention benefit.

How this product is rated for Mental Focus

Ingredient fit84

Choline account for the main saved ingredient findings. Choline receive partial recognition for their declared amounts; the comparison does not establish a proven effective focus dose.
Goal fit
Choline provide the main connection to focus; the product’s broader purposes also affect its saved fit.
Dose adequacy
Choline receive partial recognition for their declared amounts; the comparison does not establish a proven effective focus dose.

Pathways48

The saved findings emphasize acetylcholine signalling. Other evaluated pathways did not reach the coverage requirement.
Depth
The strongest saved pathway finding concerns acetylcholine signalling.
Breadth
Only acetylcholine signalling reached the coverage requirement.

Evidence74

Choline supports normal nerve signalling, but acute improvement in adequately nourished adults is not established. The saved findings recognize the declared preparation, without establishing that every claimed attention benefit applies to it.
Evidence strength
Choline supports normal nerve signalling, but acute improvement in adequately nourished adults is not established.
Studied preparation
The saved findings recognize the declared preparation, without establishing that every claimed attention benefit applies to it.

Formulation logic100

The saved findings identify no missing required ingredient partner. No configured conflicts were detected, and the counted ingredients passed the minimum amount threshold.
Partner coverage
The saved findings identify no missing required ingredient partner.
Conflicts
No configured ingredient conflict was detected in the supplied facts. This does not establish overall safety.
Effective doses
All ingredients counted in the saved findings passed its minimum amount threshold; that threshold does not prove clinical effectiveness.
Study evidence
Choline Supportive 22 studies
Cognitive Support
Impact
High effect
B+ Ingredient FitD PathwaysA- EvidenceA+ Formulation Logic
Choline · 350 mg

Choline provides a building block for acetylcholine, which is involved in memory and attention. This nutrient role explains its connection to cognition, but the supplied healthy-adult choline experiments did not show reliable memory enhancement. The saved findings give choline a contribution; that does not establish that this serving improves memory or transfer benefits from Alpha-GPC or citicoline.

How this product is rated for Cognitive Support

Ingredient fit84

Choline supplies the main cognitive-related ingredient. Its normal nutrient role does not establish memory enhancement.
Goal fit
Choline supplies the cognitive connection through its acetylcholine-precursor role.
Dose adequacy
The known choline amount contributes to the saved finding without establishing a memory-enhancing dose.

Pathways47

The saved findings emphasize acetylcholine signalling. This functional connection does not establish broad cognitive improvement.
Depth
The strongest saved finding concerns acetylcholine signalling, which does not by itself establish improved cognitive performance.
Breadth
The saved coverage is concentrated in a single cognitive-related function.

Evidence89

Vitamin B4 (Choline) anchors the saved evidence finding. Its contribution remains limited by the supplied scientific context.
Evidence strength
Vitamin B4 (Choline) leads the saved evidence finding, but the supplied population and outcome limitations still apply.
Studied preparation
The saved finding accepts the credited preparations as studied; this does not override the supplied limits on cognitive benefit.

Formulation logic100

The credited ingredients retain their individual contributions and no evaluated conflict was triggered.
Partner coverage
The credited ingredients retain their individual contributions without a missing required partner.
Conflicts
No evaluated ingredient conflict was triggered by the supplied facts.
Effective doses
The credited ingredients meet the saved amount threshold; that inclusion threshold is not a clinically proven cognitive dose.
Study evidence
Choline Supportive 76 studies

Ingredients

IngredientAmount per servingScore
Choline (Choline Bitartrate)
350 mg 84
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
C+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
Each serving provides 350 mg of choline from choline bitartrate. The whole-product cost works out to about $0.04 per 100 mg of declared choline.
How this ingredient is rated

Active Ingredient Quality & Bioavailability68

Choline bitartrate is an identified systemic source of choline. The ingredient information shows flow agents and no additives flagged by the evaluation.
Choline Form Efficacy & Bioavailability
Choline bitartrate is an identified systemic source of choline.
Formula Purity & Excipient Quality
The ingredient information shows flow agents and no additives flagged by the evaluation.

Dose, Safety & Label Transparency91

The declared choline amount is 350 mg per serving, so the nutrient amount is clear.
Choline Dose by Declared Basis
Each serving provides a declared 350 mg of choline.
Elemental Yield Transparency
The label gives the choline amount itself as 350 mg per serving.

Value100

The whole-product cost works out to about $0.04 per 100 mg of declared choline.
Price per 100 mg of Declared Choline Basis
The whole-product cost works out to about $0.04 per 100 mg of declared choline.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsCognitive Support forCholine
  2. Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
    Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
    Cohort study125,594 participantsCognitive Support forCholine
  3. Choline intake during pregnancy and child cognition at age 7 years.
    Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
    Cohort study895 participantsCognitive Support forCholine
  4. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forCholine
  5. Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
    Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
    Randomized trial52 participantsCognitive Support forCholine
  6. Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
    Guideline / consensusLiver & Detox forCholine
  7. Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
    Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
    Cross-sectional study20,643 participantsLiver & Detox forCholine
  8. Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
    Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
    Observational study80 participantsLiver & Detox forCholine
  9. Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
    Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
    Single-arm trial10 participantsLiver & Detox forCholine
  10. 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
    Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
    Cohort study88 participantsLiver & Detox forCholine
  11. Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.
    Wozniak JR; Fink BA; Fuglestad AJ; Eckerle JK; Boys CJ; Sandness KE; Radke JP; Miller NC; Lindgren C; Brearley AM; Zeisel SH; Georgieff MK · Journal of neurodevelopmental disorders · 2021
    Randomized trial31 participantsMental Focus forCholine
  12. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.
    Poly C; Massaro JM; Seshadri S; Wolf PA; Cho E; Krall E; Jacques PF; Au R · The American journal of clinical nutrition · 2012
    Cohort study1,391 participantsMental Focus forCholine
  13. Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
    Obeid R; Derbyshire E; Schön C · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis30 studies pooledMental Focus forCholine
  14. Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
    Akison LK; Kuo J; Reid N; Boyd RN; Moritz KM · Alcoholism, clinical and experimental research · 2019
    Systematic reviewMental Focus forCholine
  15. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
    Ross RG; Hunter SK; McCarthy L; Beuler J; Hutchison AK; Wagner BD; Leonard S; Stevens KE; Freedman R · The American journal of psychiatry · 2013
    Randomized trialMental Focus forCholine