$29.20 $0.24 per serving
Product analysis
Double Strength 5-HTP 200 mg may help with fullness and lower food intake, based on limited findings from small trials. Its everyday mood, sleep and stress benefits remain uncertain.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality32
5-HTP and the two vitamins have named sources or forms, making them easier to identify. Comparative ingredient quality remains uncertain, especially for ingredients whose forms are unspecified.
Ingredient Transparency81
All active ingredient amounts are disclosed, making servings easier to compare. Half of the ingredient forms remain unspecified.
Value For Money56
Value is strongest for the 5-HTP portion. Glycine is relatively costly for the amount supplied, while value for the supporting ingredients remains uncertain.
Customer Satisfaction93
Customer ratings are very positive. A large review base gives that feedback broad support.
Product Focus64
5-HTP may help fullness, while everyday mood, sleep and stress benefits remain uncertain. The small supporting ingredient amounts do not establish a stronger combined effect.
- Format
Capsule - Container
- 120 Capsule(s)
- Per serving
- $0.24
- Also available
Double Strength 5-HTP 200 mg$13.60- Customer rating
- 4.8 · 18,265 ratings
Goals
Impact
Highest effect
Vitamin B6 · 2 mg5-HTP · 200 mg
Impact
Moderate effect
Glycine · 100 mgVitamin B6 · 2 mg
Impact
Moderate effect
Glycine · 100 mg
Taurine Not classified
No linked studies yet.
Impact
Moderate effect
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Niacin (Niacinamide) | 20 mg | |
Vitamin B6 (Pyridoxine Hydrochloride) | 2 mg | |
5-HTP (Griffonia simplicifolia Seed Extract) | 200 mg | |
Glycine | 100 mg | |
Taurine | 100 mg | |
Inositol | 100 mg |
5-HTP (Griffonia simplicifolia Seed Extract) · 200 mg OverallScore85
Each serving provides 200 mg of 5-HTP at a low cost per amount of 5-HTP. The 5-HTP comes from Griffonia simplicifolia, but its standardization percentage is not specified. A warning about use with serotonin-modulating medicines is included.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
The 5-HTP comes from Griffonia simplicifolia, but its standardization percentage is not specified.
Botanical Source & Standardization
The 5-HTP comes from Griffonia simplicifolia, but its standardization percentage is not specified.
Dose, Safety & Label Transparency93
Each serving provides 200 mg of 5-HTP. A warning about use with serotonin-modulating medicines is included.
Dosage Potency & Range
Each serving provides 200 mg of 5-HTP.
Safety Warnings & Label Clarity
A warning about use with serotonin-modulating medicines is included.
Value100
The cost per amount of 5-HTP is low.
Price per 100mg 5-HTP
The cost per amount of 5-HTP is low.
Glycine · 100 mg OverallScore48
Each serving provides 100 mg of glycine, a small amount, and glycine is expensive per gram. It comes from a GMP-compliant facility. Ordinary capsule or tablet ingredients are reported.
How this ingredient is rated
Active Ingredient Quality & Bioavailability60
It comes from a GMP-compliant facility.
Glycine Sourcing and Purity Standards
It comes from a GMP-compliant facility.
Dose, Safety & Label Transparency46
The label gives the glycine amount per serving. Ordinary capsule or tablet ingredients are reported.
Clinically Relevant Dosage
A serving supplies 100 mg of glycine, a small amount.
Label Transparency and Yield Disclosure
The glycine amount is explicitly listed.
Clean Label and Excipient Quality
Ordinary capsule or tablet ingredients are reported.
Value30
The cost per gram of glycine is high.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is high.
Taurine · 100 mg OverallScore55
A serving provides 100 mg of taurine, with a high product cost relative to that amount. The source and manufacturing origin are unspecified. Testing or GMP manufacturing is claimed; a specific certification seal is not indicated.
How this ingredient is rated
Active Ingredient Quality & Bioavailability72
The taurine is described as L-taurine or free-form; a purity grade is not specified. The taurine source and manufacturing origin are not specified. The available other-ingredients information does not flag the specified artificial additives or flow agents.
Chemical Form and Purity
The taurine is described as L-taurine or free-form; a purity grade is not specified.
Sourcing and Branded Ingredients
The taurine source and manufacturing origin are not specified.
Formulation Cleanliness
The available other-ingredients information does not flag the specified artificial additives or flow agents.
Dose, Safety & Label Transparency54
The serving provides a small 100 mg amount of taurine. Testing or GMP manufacturing is claimed; a specific certification seal is not indicated.
Taurine Dosage Potency
The serving provides a small 100 mg amount of taurine.
Dose Disclosure
The taurine amount per serving is stated as 100 mg.
Quality Assurance and Testing
Testing or GMP manufacturing is claimed; a specific certification seal is not indicated.
Value20
The product cost is high relative to the taurine amount.
Price per Gram of Taurine
The product cost is high relative to the taurine amount.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
- Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
- Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
- High Dose Vitamin B6 Reduces Depression Symptoms.
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
- Associations of dietary B vitamins intakes with depression in adults.
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
- New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
- The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.