$13.60 $0.22 per serving
Product analysis
Double Strength 5-HTP 200 mg offers inexpensive 5-HTP, which may help with fullness and some mood-related symptoms. Expected mood and sleep benefits remain uncertain, and the extra ingredients do not establish a clear added benefit at their amounts.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality42
Niacinamide is clearly identified, while the comparative quality of the 5-HTP preparation and vitamin B6 remains uncertain. Several other ingredient forms are unspecified, limiting a complete quality comparison.
Ingredient Transparency81
All ingredient amounts are disclosed, but only some forms are identified. The amounts are therefore easier to compare than the complete preparations.
Value For Money60
The 5-HTP content offers favorable value, while glycine is costly for the amount supplied. Other ingredients have mixed or uncertain value, so the clearest cost advantage lies in 5-HTP.
Customer Satisfaction93
Customers report very positive satisfaction across a very large review pool. Those ratings cannot establish whether the formula improves mood or sleep.
Product Focus64
5-HTP provides the main connection to mood-related processes, possible fullness and sleep support. Several added ingredients contribute little clear extra benefit at their stated amounts.
- Format
Capsule - Container
- 60 Capsule(s)
- Per serving
- $0.22
- Also available
Double Strength 5-HTP 200 mg$29.20- Customer rating
- 4.8 · 17,043 ratings
Goals
Impact
Highest effect
Vitamin B6 · 2 mg5-HTP · 200 mg
Impact
Moderate effect
Glycine · 100 mg
Taurine Not classified
No linked studies yet.
Impact
Moderate effect
Impact
Moderate effect
Glycine · 100 mgVitamin B6 · 2 mg
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Niacin (Niacinamide) | 20 mg | |
Vitamin B6 (Pyridoxine Hydrochloride) | 2 mg | |
5-HTP (Griffonia simplicifolia Seed Extract) | 200 mg | |
Glycine | 100 mg | |
Taurine | 100 mg | |
Inositol | 100 mg |
5-HTP (Griffonia simplicifolia Seed Extract) · 200 mg OverallScore85
Each serving supplies 200 mg of 5-HTP, with a competitive estimated cost for the amount supplied. Griffonia simplicifolia is named, but its 5-HTP standardization percentage is not stated. The label includes a warning about serotonin-related medicines.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
Griffonia simplicifolia is named, but its 5-HTP standardization percentage is not stated.
Botanical Source & Standardization
Griffonia simplicifolia is named, but its 5-HTP standardization percentage is not stated.
Dose, Safety & Label Transparency93
The serving provides 200 mg. The label includes a warning about serotonin-related medicines.
Dosage Potency & Range
200 mg per serving is a higher-strength amount.
Safety Warnings & Label Clarity
The label includes a warning about serotonin-related medicines.
Value100
The estimated cost per 100 mg of 5-HTP is competitive; the full serving price is attributed to 5-HTP.
Price per 100mg 5-HTP
The estimated cost per 100 mg of 5-HTP is competitive; the full serving price is attributed to 5-HTP.
Niacin (Niacinamide) · 20 mg OverallScore73
A serving provides 20 mg of niacin, with a moderate cost per serving based on the full product price. It uses Niacinamide. Niacinamide is generally non-flushing, but no explicit no-flush claim is recorded.
How this ingredient is rated
Active Ingredient Quality & Bioavailability86
It uses Niacinamide. The named Niacinamide is a standard form of vitamin B3.
Niacin Form & Goal Alignment
It uses Niacinamide.
Precursor Source Quality
The named Niacinamide is a standard form of vitamin B3.
Dose, Safety & Label Transparency67
The serving provides 20 mg of niacin, a modest amount. Niacinamide is generally non-flushing, but no explicit no-flush claim is recorded.
Clarity of Chemical Form
The label identifies Niacinamide as the form.
Form-Specific Dosage Efficacy
The serving provides 20 mg of niacin, a modest amount.
Flush Risk & Safety Labeling
Niacinamide is generally non-flushing, but no explicit no-flush claim is recorded.
Value60
The full product price per serving is moderate for the niacin form.
Price Per Effective Serving
The full product price per serving is moderate for the niacin form.
Glycine · 100 mg OverallScore48
Each serving provides 100 mg of glycine, a small amount, and glycine is expensive per gram. It comes from a GMP-compliant facility. Ordinary capsule or tablet ingredients are reported.
How this ingredient is rated
Active Ingredient Quality & Bioavailability60
It comes from a GMP-compliant facility.
Glycine Sourcing and Purity Standards
It comes from a GMP-compliant facility.
Dose, Safety & Label Transparency46
The label gives the glycine amount per serving. Ordinary capsule or tablet ingredients are reported.
Clinically Relevant Dosage
A serving supplies 100 mg of glycine, a small amount.
Label Transparency and Yield Disclosure
The glycine amount is explicitly listed.
Clean Label and Excipient Quality
Ordinary capsule or tablet ingredients are reported.
Value30
The cost per gram of glycine is high.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is high.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
- Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
- Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
- High Dose Vitamin B6 Reduces Depression Symptoms.
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
- Associations of dietary B vitamins intakes with depression in adults.
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
- New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
- The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.