$37.00 $0.61 per serving
Product analysis
HomocysteX Plus supplies B vitamins for normal blood formation and energy use, with benefits clearest when intake is low.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality66
Vitamin B2 has a favorable form, and B6’s form is clearly identified. There is less information to compare the quality of folate, B12 and betaine confidently.
Ingredient Transparency93
Amounts and most ingredient forms are disclosed, making the serving straightforward to check. The unspecified betaine form limits a complete comparison.
Value For Money43
Riboflavin offers fair value, while B6’s value is more limited. Value for folate and B12 remains uncertain because the necessary comparisons are unavailable.
Customer Satisfaction88
Customer feedback is very positive across a large body of ratings. Those ratings describe satisfaction without establishing heart or cognitive benefits.
Product Focus66
The compact formula addresses related nutritional functions across several health aims. Helping process homocysteine, a normal blood compound, does not by itself establish fewer heart problems or better cognition.
- Format
Capsule - Container
- 60 Capsule(s)
- Per serving
- $0.61
- Customer rating
- 4.8 · 2,295 ratings
Goals
Impact
Highest effect
Folate · 1360 mcg DFEVitamin B12 · 1000 mcg
B vitamins supply nutrients used in normal energy metabolism and blood formation. The nutritional contributions are most useful when intake is low; extra benefit with adequate intake is not established.
How this product is rated for Everyday Health
Ingredient fit78
Vitamin B9 (Folate) and the other relevant nutrients provide the main connection to general health. Additional actives make the formula less focused on this goal.
Goal fit
Relevant nutrients contribute to general health, alongside other actives with less direct support for this goal.
Dose adequacy
The relevant amounts provide partial nutritional contributions relative to the saved comparison amounts.
Pathways80
The strongest area is one-carbon metabolism and blood formation. Contributions also reach the saved coverage level across energy metabolism cofactors, one-carbon metabolism and blood formation.
Depth
The strongest supported area is one-carbon metabolism and blood formation, through the relevant nutrient contributions.
Breadth
The supported areas reaching the saved coverage level are energy metabolism cofactors, one-carbon metabolism and blood formation.
Evidence82
Vitamin B9 (Folate) provides the strongest supported contribution. The supplied context limits routine expectations to filling nutritional gaps rather than improving outcomes in adequately nourished adults.
Evidence strength
Vitamin B9 (Folate) provides the strongest supported contribution here; usefulness remains conditional on the relevant nutritional or population context.
Studied preparation
The relevant preparations match those recognized by the saved findings; this does not establish superiority of a form or delivery method.
Formulation logic94
The relevant ingredients can contribute independently, and no configured conflict was found. Their presence together does not establish an added combination benefit.
Partner coverage
The relevant ingredients can contribute independently or have their required partners present; no extra combination benefit is established.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
Some relevant ingredients fall below the saved amount threshold: Vitamin B12.
Impact
Moderate effect
Folate relates to cell division, while the B vitamins play cofactor roles in normal nutrition. Those roles don't tell us whether taking this combination improves hair growth. Individual nutrient amounts therefore don't provide a reliable expectation of regrowth, and combining them doesn't automatically create an added hair benefit.
How this product is rated for Hair Health
Ingredient fit61
Several nutrients are present, but a broader ingredient list does not imply broader hair regrowth.
Goal fit
Several nutrients are present, but a broader ingredient list does not imply broader hair regrowth.
Dose adequacy
The selected serving declares Riboflavin (B2) 25 mg and Vitamin B6 15 mg; these amounts do not imply a predictable amount of hair regrowth.
Pathways0
The main connection is nutrient biology relevant to hair; a biological role alone does not predict regrowth.
Depth
The main connection is nutrient biology relevant to hair; a biological role alone does not predict regrowth.
Breadth
Several biological roles do not necessarily produce separate or additive hair benefits.
Evidence68
The nutrients have normal biological roles, but a routine hair-growth benefit remains unclear.
Evidence strength
The nutrients have normal biological roles, but a routine hair-growth benefit remains unclear.
Studied preparation
The declared nutrient identities do not guarantee that the serving will reproduce a particular hair outcome.
Formulation logic88
No additional ingredient partner or particular ingredient conflict is identified. The combination alone does not imply added hair benefit.
Partner coverage
No additional ingredient partner is required for the independent nutrient roles described here.
Conflicts
No particular ingredient conflict is identified for the serving.
Effective doses
The selected serving declares Riboflavin (B2) 25 mg and Vitamin B6 15 mg; these amounts do not imply a predictable amount of hair regrowth.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Riboflavin (Riboflavin 5-Phosphate Sodium) | 25 mg | |
Vitamin B6 (Pyridoxal 5-Phosphate) | 15 mg | |
Folate (Quatrefolic) | 1360 mcg DFE | |
MecobalActive (Vitamin B12) | 1000 mcg | |
Trimethylglycine | 700 mg |
Vitamin B6 (Pyridoxal 5-Phosphate) · 15 mg OverallScore77
Riboflavin (Riboflavin 5-Phosphate Sodium) · 25 mg OverallScore85
A serving provides 25 mg riboflavin, a moderate amount, from riboflavin 5'-phosphate. The label states the riboflavin amount itself.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
The ingredient is sodium riboflavin 5'-phosphate, an active coenzyme form.
Riboflavin Form Quality
The ingredient is sodium riboflavin 5'-phosphate, an active coenzyme form.
Dose, Safety & Label Transparency88
A serving provides 25 mg riboflavin, a moderate amount. No artificial colors or synthetic sweeteners were flagged in the available ingredient information.
Dosage for Energy & Metabolism
A serving provides 25 mg riboflavin, a moderate amount.
R5P Elemental Yield Transparency
The declared 25 mg is the riboflavin amount, not just the weight of the phosphate compound.
Additive Purity
No artificial colors or synthetic sweeteners were flagged in the available ingredient information.
Value50
The whole-product serving costs about $0.62.
Price per Serving Value
The whole-product serving costs about $0.62.
Vitamin B12 · 1000 mcg OverallScore30
A serving lists 1,000 mcg of vitamin B12, but the specific form is not identified in the saved facts. The whole-product price corresponds to about $0.62 per 1,000 mcg of B12.
How this ingredient is rated
Active Ingredient Quality & Bioavailability0
The saved facts do not identify a specific form of vitamin B12.
Bioactive B12 Form Selection
The saved facts do not identify a specific form of vitamin B12.
Dose, Safety & Label Transparency70
The serving lists 1,000 mcg of vitamin B12. The B12 amount is listed, but its form is not identified in the saved facts.
Therapeutic Dosage Level
The stated serving provides 1,000 mcg of vitamin B12.
Label and Form Transparency
The B12 amount is listed, but its form is not identified in the saved facts.
Value10
Based on the whole-product price, the cost corresponds to about $0.62 per 1,000 mcg of B12.
Price per 1,000 mcg B12
Based on the whole-product price, the cost corresponds to about $0.62 per 1,000 mcg of B12.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
- The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
- Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
- The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
- Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
- Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
- Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
- A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
- Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
- The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
- Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
- Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
- Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
- Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
- Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
- Factors Associated with Premature Hair Graying in a Young Indian Population.
- Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
- Hair Loss After Laparoscopic Sleeve Gastrectomy.
- Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.