OptiStatin CoQ10-SR

OptiStatin CoQ10-SR

Quality of Life4.7 (84 ratings)
Format:Capsule Quantity: 30 Vegicap(s) · 30 servings
Goals
$23.96 $0.79 per serving

Product analysis

65 out of 100

OptiStatin CoQ10-SR combines CoQ10 with vitamins and selenium, with limited evidence linking CoQ10 to blood-vessel function. The unspecified CoQ10 preparation makes comparison with the preparations behind those findings harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality62

Selenium has a clearly identified form, while the CoQ10 preparation is unspecified. Vitamin K is described as K2 with more specific information pointing to MK-7, but its identity is not consistently clear.

Ingredient Transparency91

The listed amounts are disclosed, helping compare servings. Several preparations remain unspecified, limiting a more precise comparison.

Value For Money34

Selenium and vitamin K compare poorly on cost, while CoQ10 offers limited value. Vitamin D value remains uncertain, so the combination has no clear price advantage.

Customer Satisfaction71

Customer ratings are generally positive within a small review base. The feedback does not establish effectiveness or safety.

Product Focus75

CoQ10 has limited links to selected measures of blood-vessel function, while the vitamins and selenium mainly contribute to normal nutrition. These roles do not establish an added benefit from combining the ingredients.

Format
Capsule
Container
30 Vegicap(s)
Per serving
$0.79
Customer rating
4.7 · 84 ratings
Report analysis

Goals

Heart Health
Impact
Highest effect
A- Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin K · 180 mcgCoenzyme Q-10 · 100 mgVitamin D · 50 mcg
Study evidence
Selenium Mixed 89 studies
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Cardiovascular Support
Impact
Highest effect
B+ Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin K · 180 mcgVitamin D · 50 mcgCoenzyme Q-10 · 100 mgSelenium · 200 mcg
Study evidence
Selenium Supportive 107 studies
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies
Longevity
Impact
Highest effect
A- Ingredient FitB+ PathwaysB EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mgVitamin K · 180 mcgVitamin D · 50 mcg
Study evidence
Selenium Supportive 27 studies
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Everyday Health
Impact
Highest effect
A- Ingredient FitB+ PathwaysB EvidenceA+ Formulation Logic
Vitamin D · 50 mcgVitamin K · 180 mcgSelenium · 200 mcg
Study evidence
Selenium Supportive 70 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Immunity
Impact
Highest effect
B Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 50 mcgSelenium · 200 mcg
Study evidence
Selenium Mixed 37 studies
Vitamin D Supportive 85 studies
Bone Health
Impact
High effect
C Ingredient FitC PathwaysA EvidenceB Formulation Logic
Vitamin K · 180 mcgVitamin D · 50 mcg
Study evidence
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
50 mcg
Selenium (L-Selenomethionine)
200 mcg 86
Coenzyme Q10
100 mg 42
MenaQ7 (Vitamin K2)
180 mcg 70
Gluten Free Adults 18–50 Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving provides 200 mcg of selenium, an amount used in research on antioxidant and thyroid support. The estimated cost per 200 mcg of selenium is fairly high, based on the full serving price. It uses L-Selenomethionine. The label specifies the L form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses L-Selenomethionine. The label specifies the L form.
Selenium Chemical Form
It uses L-Selenomethionine.
Form Transparency & Isomer Specificity
The label specifies the L form.

Dose, Safety & Label Transparency100

200 mcg is an amount used in research on antioxidant and thyroid support. The 200 mcg serving is below the 400 mcg adult upper intake level, leaving room for selenium from food.
Dosage Efficacy Sweet Spot
200 mcg is an amount used in research on antioxidant and thyroid support.
Safety Margin & UL Adherence
The 200 mcg serving is below the 400 mcg adult upper intake level, leaving room for selenium from food.

Value30

The estimated cost per 200 mcg of selenium is fairly high, based on the full serving price.
Price per 200 mcg Serving
The estimated cost per 200 mcg of selenium is fairly high, based on the full serving price.
B+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value
A serving supplies 180 mcg of MK-7 at a high cost per serving. The MK-7 isomer is not specified.
How this ingredient is rated

Active Ingredient Quality & Bioavailability82

The vitamin K comes as vitamin K2 as MK-7. The MK-7 isomer is unspecified.
Vitamin K Form (MK-7 vs. MK-4 vs. K1)
The source is vitamin K2 as MK-7.
MK-7 Isomer Disclosure
The MK-7 isomer is not specified as trans or all-trans.

Dose, Safety & Label Transparency82

The serving provides 180 mcg of MK-7. The active panel names K2 but does not specify the subtype.
Vitamin K2 (MK-7) Dosage Efficacy
180 mcg of MK-7 is provided per serving.
Form and Subtype Transparency
K2 is named on the active panel, but the subtype is not specified there.

Value20

The cost per serving is high.
Price per Effective MK-7 Serving
The cost per serving is high.
Coenzyme Q-10 · 100 mg OverallScore42
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value
A serving provides 100 mg of CoQ10 per serving, and the cost per serving is somewhat high. The form of CoQ10 is unclear.
How this ingredient is rated

Active Ingredient Quality & Bioavailability12

The form of CoQ10 is unclear. No liposomal, micellar or nanoemulsion claim, or pepper extract, is available in the details.
Molecular Form: Ubiquinol vs. Ubiquinone
The CoQ10 form is not specified, so whether it is ubiquinone or ubiquinol is unclear.
Formulation & Absorption Enhancers
No liposomal, micellar or nanoemulsion claim, or pepper extract, is available in the details.

Dose, Safety & Label Transparency72

The serving provides 100 mg of CoQ10 per serving. The available ingredient panel does not list the specified concerning additives or standard fillers.
Clinical Dosage Alignment
The serving provides 100 mg of CoQ10 per serving.
Label Transparency & Fillers
The amount is stated, and the available ingredient panel does not list the specified concerning additives or standard fillers.

Value40

The cost per serving is somewhat high.
Price Per Effective Serving
The cost per serving is somewhat high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  2. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  3. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  4. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  5. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  6. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  7. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  8. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  9. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  10. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  11. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  12. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  13. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  14. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  15. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  16. Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.
    Rayman MP; Stranges S; Griffin BA; Pastor-Barriuso R; Guallar E · Annals of internal medicine · 2011
    Randomized trial501 participantsCardiovascular Support Heart Health forSelenium
  17. Association of selenium and cadmium with heart failure and mortality based on the National Health and Nutrition Examination Survey.
    Xing X; Xu M; Yang L; Shao C; Wang Y; Qi M; Niu X; Gao D · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Cohort study15,689 participantsCardiovascular Support forSelenium
  18. Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.
    Zhu D; Zhong Q; Lin T; Song T · Frontiers in nutrition · 2023
    Cohort study3,063 participantsCardiovascular Support Heart Health forSelenium
  19. Selenium status in the body and cardiovascular disease: a systematic review and meta-analysis.
    Kuria A; Tian H; Li M; Wang Y; Aaseth JO; Zang J; Cao Y · Critical reviews in food science and nutrition · 2021
    Meta-analysis13 studies pooledCardiovascular Support forSelenium
  20. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledCardiovascular Support Everyday Health forSelenium