High Volume Melon Berry Twist

High Volume Melon Berry Twist

PEScience4.6 (79 ratings)
Format:Powder Quantity: 8 Ounce(s) · 18 servings
Goals
$39.99 $2.22 per serving
iHerb$39.99

About this product

L-citrulline is individually listed at 4,000 mg, with 2,000 mg of arginine nitrate and 1,000 mg of agmatine alongside it. Those amounts create a clear pump-oriented formula without caffeine.

The overlapping blood-flow ingredients may provide a more noticeable pre-workout effect than citrulline alone. They also increase the chance of headache or lightheadedness for sensitive users.

Melon Berry Twist is difficult to justify on value when the main goal is simply obtaining citrulline. It better fits someone who wants this exact multi-active blend and prefers the flavor enough to accept the premium.

Who is it for
  • Stimulant-sensitive adults seeking workout pump support
  • Users who prefer a flavored powder over capsules
Best for
  • A caffeine-free pre-workout routine
  • People specifically wanting citrulline, nitrate, and agmatine together

Pros

  • Provides 4,000 mg of L-citrulline
  • Discloses the main pump-ingredient amounts
  • Uses a stimulant-free exercise formula

Cons

  • Citrulline-specific value is poor
  • Only 18 servings are supplied
  • The complex blend is unnecessary for basic citrulline use

Warnings

  • Arginine nitrate combined with L-citrulline and agmatine may cause headache, flushing, or lightheadedness.
  • Do not combine the nitrate-containing formula with nitrate medicine or erectile-dysfunction medicine without professional guidance.
  • The combined blood-flow ingredients may add to antihypertensive medicine and lower blood pressure further.

Product analysis

65 out of 100
A well-disclosed stimulant-free pump blend with useful citrulline, but poor value and overlapping vasodilatory effects limit broad appeal.

AI assessment of the formula, label and price. How scoring works

Nutrient quality85

Meaningful citrulline, nitrate, and agmatine amounts provide strong pump-formula depth. The assertive vasodilator combination may not suit users taking blood-pressure-lowering medicines.

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Ingredient transparency61

Main active amounts are visible, but the performance matrix remains partly opaque. Complete directions and inactive powder ingredients are also missing.

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Customer satisfaction62

The supplied average is strong and supported by moderate volume. No review themes were provided, so consistency and purpose-specific experience cannot be assessed.

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Value for money47

Strong pump doses provide meaningful quality value. A very high serving cost and partly hidden matrix make the product weakly competitive.

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Format
Powder
Container
8 Ounce(s)
Per serving
$2.22
Customer rating
4.6 · 79 ratings
Report analysis

Goals

Fitness
Fitness
Impact
Moderate effect
C+ Ingredient FitC- PathwaysC EvidenceA Formulation Logic
Citrulline · 4000 mg
Study evidence
Citrulline Supportive 45 studies
Vitamin C No effect 17 studies
Weight Gain
Weight Gain
Impact
Lower effect
D+ Ingredient FitF PathwaysD EvidenceA- Formulation Logic
Citrulline · 4000 mg
Study evidence
Citrulline No effect 8 studies
Energy
Energy
Impact
High effect
B Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic
Study evidence
Citrulline No effect 14 studies
Heart Health
Heart Health
Impact
High effect
D+ Ingredient FitD+ PathwaysA- EvidenceA- Formulation Logic
Citrulline · 4000 mg
Study evidence
Citrulline Supportive 39 studies
Cardiovascular Support
Arterial Integrity and Protection
Cardiovascular Support
Impact
High effect
C Ingredient FitD+ PathwaysB EvidenceA Formulation Logic
Vitamin C · 250 mgCitrulline · 4000 mg

High Volume Melon Berry Twist includes 4,000 mg citrulline and 250 mg vitamin C, while taurine is listed without a confirmed individual amount or preparation. Citrulline gives it a clear link to endothelial nitric-oxide function, but other cardiovascular pathways have little support and the formula also contains agmatine and arginine nitrate.

How this product is rated for Cardiovascular Support

Ingredient fit61

Citrulline, taurine and vitamin C relate to the goal; agmatine and arginine nitrate are additional active ingredients.
Goal fit
Most of the relevant focus comes from three ingredients, with only agmatine and arginine nitrate outside that group.
Dose adequacy
Citrulline and vitamin C have clear amounts, but taurine's individual amount and preparation are unresolved.

Pathways54

Endothelial nitric oxide is the main route, with little support across the other target pathways.
Depth
Endothelial nitric-oxide function is the best-covered route.
Breadth
Only endothelial nitric-oxide function has substantial coverage.

Evidence79

Citrulline has the strongest listed evidence among ingredients at relevant amounts, and two preparations have been studied in trials.
Evidence strength
Citrulline has the strongest listed evidence among ingredients at effective amounts.
Studied preparation
Two ingredients at effective amounts use preparations studied in trials.

Formulation logic92

Citrulline and vitamin C need no missing partner, and no listed conflict applies; taurine's individual amount remains unresolved.
Partner coverage
Each ingredient contributing to the goal works alone or has its needed partner.
Conflicts
The available ingredients do not trigger a listed conflict.
Effective doses
Citrulline and vitamin C meet their dose references; taurine's amount cannot be confirmed.
Study evidence
Citrulline Supportive 33 studies
Vitamin C Supportive 101 studies
Muscle Gain
Muscle Gain
Impact
Moderate effect
C+ Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Citrulline · 4000 mg
Study evidence
Citrulline Supportive 15 studies

Ingredients

IngredientAmount per servingScore
Vitamin C
250 mg
L-Citrulline
4000 mg
Performance Pump Matrix
3750 mg
NO3-T (Arginine Nitrate)
 2000 mg
Agmatine Sulfate
1000 mg
Adults 18–50 Women
Report overview
Loading alternative details
83 Performance

L-Citrulline 2000 mg

AN Amazing Nutrition Amazing Formulas

Pure L-citrulline provides a clean single-ingredient formula at a clearly disclosed amount. Compared with High Volume Melon Berry Twist, the larger citrulline serving without a proprietary blend provides a stronger ingredient-based fit for nitric-oxide or exercise support, although the amount still provides only moderate performance support.

67 Performance

Pump-Ocalypse Blue Raz

Bucked Up

Glycerol, citrulline, arginine, and agmatine form a coherent stimulant-free pump blend. Compared with High Volume Melon Berry Twist, the broader hydration and nitric-oxide ingredient profile provides a stronger ingredient-based fit for nitric-oxide or exercise support, although several amounts are moderate and a mushroom blend is opaque.

65 Performance

High Volume Blue Frost

PEScience

L-citrulline, arginine nitrate, and agmatine create a substantial stimulant-free pump formula. Compared with High Volume Melon Berry Twist, the broader pump-oriented combination of citrulline, nitrate, and agmatine provides a stronger ingredient-based fit for nitric-oxide or exercise support, although part of the matrix is hidden and arginine nitrate may interact with nitrate or blood-pressure medicines.

79 Budget

L-Arginine + L-Citrulline 750 mg

Nutricost

Clearly separated L-arginine and L-citrulline provide a simple nitric-oxide-support combination. The supplied data does not show a lower cost per serving than High Volume Melon Berry Twist; it is included because fewer than three eligible lower-cost products are available, and both amounts are too low for targeted performance use without multiple capsules.

78 Budget

L-Arginine L-Citrulline Complex 1000 mg

Best Naturals

L-arginine hydrochloride and free-form L-citrulline create a focused two-amino-acid formula. The supplied data does not show a lower cost per serving than High Volume Melon Berry Twist; it is included because fewer than three eligible lower-cost products are available, and the citrulline amount is far below targeted performance use.

78 Budget

Arginine & Citrulline 500 mg / 250 mg

NOW Sports

Clearly disclosed L-arginine and L-citrulline provide a concise nitric-oxide-support formula. The supplied data does not show a lower cost per serving than High Volume Melon Berry Twist; it is included because fewer than three eligible lower-cost products are available, and both serving amounts are far below targeted performance ranges.

79 Value

L-Citrulline 1000 mg

Nutricost

Pure L-citrulline provides a clean and transparent single-ingredient formula. Compared with High Volume Melon Berry Twist, its ingredient advantages and the simple formula and clearly disclosed citrulline amount support a more favorable quality-to-cost balance, although the amount remains below common performance use.

77 Value

L-Citrulline 500 mg

California Gold Nutrition

Pure L-citrulline provides a clean, easy-to-assess single-ingredient formula. Compared with High Volume Melon Berry Twist, its ingredient advantages and the transparent single-ingredient design support a more favorable quality-to-cost balance, although the citrulline amount is well below common performance use.

78 Value

L-Arginine L-Citrulline Complex

Source Naturals

A focused L-arginine and L-citrulline combination offers clearly disclosed amino-acid support. Compared with High Volume Melon Berry Twist, its ingredient advantages and the concise arginine-citrulline pairing support a more favorable quality-to-cost balance, although citrulline is far below targeted use and arginine may add to blood-pressure-lowering medicines.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.
    Xie S; Li S; Shaharudin S · Journal of sports science & medicine · 2023
    Meta-analysis303 participants7 studies pooledFitness forCitrulline
  2. Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study.
    Haugen ME; Vårvik FT; Grgic J; Studsrud H; Austheim E; Zimmermann EM; Falch HN; Larsen S; van den Tillaar R; Bjørnsen T · European journal of nutrition · 2023
    Randomized trial35 participantsFitness forCitrulline
  3. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
    Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
    Meta-analysis415 participants15 studies pooledCardiovascular Support forCitrulline
  4. Micronutrient Supplementation to Reduce Cardiovascular Risk.
    An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
    Meta-analysis883,627 participants884 studies pooledCardiovascular Support forCitrulline
  5. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
    Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Randomized trial10 participantsCardiovascular Support forCitrulline
  6. Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
    Randomized trial25 participantsCardiovascular Support Heart Health forCitrulline
  7. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
    Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
    Randomized trial15 participantsCardiovascular Support forCitrulline
  8. Vitamin C may reduce troponin and CKMB levels after PCI and CABG: a meta-analysis.
    Rozemeijer S; Hemilä H; van Baaren M; de Man AME · BMC cardiovascular disorders · 2023
    Meta-analysis872 participants7 studies pooledCardiovascular Support forVitamin C
  9. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.
    Taddei S; Virdis A; Ghiadoni L; Magagna A; Salvetti A · Circulation · 1998
    Clinical trial49 participantsCardiovascular Support forVitamin C
  10. Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study.
    Boonthongkaew C; Tong-Un T; Kanpetta Y; Chaungchot N; Leelayuwat C; Leelayuwat N · The Chinese journal of physiology · 2021
    Randomized trial24 participantsCardiovascular Support forVitamin C
  11. Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial.
    Ren J; Liang J; Wang J; Yin B; Zhang F; Li X; Zhu S; Tian H; Cui Q; Song J; Liu G; Ling W; Ma Y · Ecotoxicology and environmental safety · 2022
    Randomized trial58 participantsCardiovascular Support forVitamin C
  12. Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes.
    Mullan BA; Young IS; Fee H; McCance DR · Hypertension (Dallas, Tex. : 1979) · 2003
    Randomized trial30 participantsCardiovascular Support forVitamin C
  13. Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.
    Vårvik FT; Bjørnsen T; Gonzalez AM · International journal of sport nutrition and exercise metabolism · 2021
    Meta-analysis137 participants8 studies pooledEnergy forCitrulline
  14. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study.
    Suzuki T; Morita M; Kobayashi Y; Kamimura A · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial22 participantsEnergy forCitrulline
  15. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
    Pérez-Guisado J; Jakeman PM · Journal of strength and conditioning research · 2010
    Randomized trial41 participantsEnergy forCitrulline
  16. Citrulline/malate promotes aerobic energy production in human exercising muscle.
    Bendahan D; Mattei JP; Ghattas B; Confort-Gouny S; Le Guern ME; Cozzone PJ · British journal of sports medicine · 2002
    Single-arm trial18 participantsEnergy forCitrulline
  17. The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
    Farney TM; Bliss MV; Hearon CM; Salazar DA · Journal of strength and conditioning research · 2019
    Randomized trial12 participantsEnergy forCitrulline
  18. Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.
    Buckinx F; Gouspillou G; Carvalho LP; Marcangeli V; El Hajj Boutros G; Dulac M; Noirez P; Morais JA; Gaudreau P; Aubertin-Leheudre M · Journal of clinical medicine · 2020
    Randomized trial56 participantsFitness Muscle Gain forCitrulline
  19. Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.
    Buckinx F; Marcangeli V; Pinheiro Carvalho L; Dulac M; Hajj Boutros G; Gouspillou G; Gaudreau P; Morais J; Noirez P; Aubertin-Leheudre M · Nutrients · 2020
    Randomized trial73 participantsFitness forCitrulline
  20. Effects of Citrulline alone or combined with exercise on muscle mass, muscle strength, and physical performance among older adults: a systematic review.
    Aubertin-Leheudre M; Buckinx F · Current opinion in clinical nutrition and metabolic care · 2021
    Systematic review250 participants6 studies pooledFitness Muscle Gain forCitrulline
  21. Combined Vs. Single Supplementation of L-Citrulline and Sodium Bicarbonate During Sprint Interval Training in Basketball Players: Effects on Physical Performance and Hormonal Adaptations.
    Wang Y; Wang Y; Qian K · Journal of sports science & medicine · 2025
    Randomized trial40 participantsFitness forCitrulline
  22. Inter-individual variability in redox and performance responses after antioxidant supplementation: A randomized double blind crossover study.
    Margaritelis NV; Nastos GG; Vasileiadou O; Chatzinikolaou PN; Theodorou AA; Paschalis V; Vrabas IS; Kyparos A; Fatouros IG; Nikolaidis MG · Acta physiologica (Oxford, England) · 2023
    Randomized trial44 participantsFitness forVitamin C
  23. Antioxidant supplementation, redox deficiencies and exercise performance: A falsification design.
    Margaritelis NV; Paschalis V; Theodorou AA; Kyparos A; Nikolaidis MG · Free radical biology & medicine · 2021
    Randomized trial73 participantsFitness forVitamin C
  24. A significant relationship between plasma vitamin C concentration and physical performance among Japanese elderly women.
    Saito K; Yokoyama T; Yoshida H; Kim H; Shimada H; Yoshida Y; Iwasa H; Shimizu Y; Kondo Y; Handa S; Maruyama N; Ishigami A; Suzuki T · The journals of gerontology. Series A, Biological sciences and medical sciences · 2012
    Cross-sectional study655 participantsFitness forVitamin C
  25. Low vitamin C values are linked with decreased physical performance and increased oxidative stress: reversal by vitamin C supplementation.
    Paschalis V; Theodorou AA; Kyparos A; Dipla K; Zafeiridis A; Panayiotou G; Vrabas IS; Nikolaidis MG · European journal of nutrition · 2016
    Clinical trial20 participantsFitness forVitamin C
  26. Low dietary vitamin C intake is associated with low muscle strength among elderly Korean women.
    Park CY; Shin S · Nutrition research (New York, N.Y.) · 2024
    Cross-sectional study14,844 participantsFitness forVitamin C
  27. Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trials.
    Yang HH; Li XL; Zhang WG; Figueroa A; Chen LH; Qin LQ · Nutrition & metabolism · 2022
    Meta-analysis8 studies pooledHeart Health forCitrulline
  28. Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.
    Rodríguez-Carrillo AA; Espinoza-Vargas MR; Vargas-Ortiz K; Ibarra-Reynoso LDR; Olvera-Juárez M; Gómez-Ojeda A; Garay-Sevilla ME; Figueroa A · Nutrients · 2025
    Randomized trial44 participantsHeart Health forCitrulline
  29. Vascular effects of l-citrulline supplementation in healthy adults are largely influenced by the prehypertensive range of blood pressure: A double-blind, randomized, placebo-controlled, parallel-group study.
    Nogimura D; Nagaoka K; Ogino K; Ogino N; Moriyasu K; Morita M · Nutrition research (New York, N.Y.) · 2026
    Randomized trial66 participantsHeart Health forCitrulline
  30. The Assessment of short-term effect of L-Citrulline on endothelial function via FMD to NMD ratio in known CAD patients: A randomized, cross-over clinical trial (Clinical trial number: NCT02638727).
    Safi M; Mahjoob MP; Nateghi S; Khaheshi I; Akbarzadeh MA; Naderian M · Romanian journal of internal medicine = Revue roumaine de medecine interne · 2017
    Randomized trial30 participantsHeart Health forCitrulline
  31. Impact of L-citrulline supplementation and whole-body vibration training on arterial stiffness and leg muscle function in obese postmenopausal women with high blood pressure.
    Figueroa A; Alvarez-Alvarado S; Ormsbee MJ; Madzima TA; Campbell JC; Wong A · Experimental gerontology · 2015
    Randomized trial41 participantsMuscle Gain forCitrulline
  32. Citrulline Supplementation Improves Microvascular Function and Muscle Strength in Middle-Aged and Older Adults with Type 2 Diabetes.
    Figueroa A; Dillon KN; Levitt DE; Kang Y · Nutrients · 2025
    Randomized trial16 participantsMuscle Gain forCitrulline
  33. Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.
    Jourdan M; Nair KS; Carter RE; Schimke J; Ford GC; Marc J; Aussel C; Cynober L · Clinical nutrition (Edinburgh, Scotland) · 2016
    Randomized trial8 participantsMuscle Gain forCitrulline
  34. Effects of Citrulline Supplementation on Body Weight in Patients With Hepatobiliary Pancreatic Surgery.
    Yang JA; Lee KE; Park JH; Yee J; Kim JY; Gwak HS · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2020
    Cohort study138 participantsWeight Gain forCitrulline
  35. Impact of high-intensity interval training with or without l-citrulline on physical performance, skeletal muscle, and adipose tissue in obese older adults.
    Marcangeli V; Youssef L; Dulac M; Carvalho LP; Hajj-Boutros G; Reynaud O; Guegan B; Buckinx F; Gaudreau P; Morais JA; Mauriège P; Noirez P; Aubertin-Leheudre M; Gouspillou G · Journal of cachexia, sarcopenia and muscle · 2022
    Clinical trial81 participantsWeight Gain forCitrulline
  36. Synergistic effect of long-term L-citruline supplementation combined with exercise on body composition in adults: A systematic review and meta-analysis of randomized controlled trials.
    Wang W; Cai S; Liu K; Luo P · Complementary therapies in medicine · 2026
    Meta-analysis9 studies pooledWeight Gain forCitrulline
  37. Effects of Citrulline or Watermelon Supplementation on Body Composition: A Systematic Review and Dose-Response Meta-Analysis.
    Ashtary-Larky D; Mohammadi S; Mousavi SAH; Hajizadeh L; Candow DG; Forbes SC; Afrisham R; Farrokhi V; Antonio J; Suzuki K · Nutrients · 2025
    Meta-analysis21 studies pooledWeight Gain forCitrulline
  38. Impact of 3-week citrulline supplementation on postprandial protein metabolism in malnourished older patients: The Ciproage randomized controlled trial.
    Bouillanne O; Melchior JC; Faure C; Paul M; Canouï-Poitrine F; Boirie Y; Chevenne D; Forasassi C; Guery E; Herbaud S; Le Corvoisier P; Neveux N; Nivet-Antoine V; Astier A; Raynaud-Simon A; Walrand S; Cynober L; Aussel C · Clinical nutrition (Edinburgh, Scotland) · 2020
    Randomized trial24 participantsWeight Gain forCitrulline