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Aquatic Beauty

NOW Solutions
4.0
★ ★ ★ ★ ★
(124 ratings)
Hyaluronic Acid 120 mg
Astaxanthin 2 mg
Collagen 2000 mg
Protein (unspecified) 2 Gram(s)
Product Image
Score80
A well-designed hydration and collagen blend uses clear forms and complementary actives, with moderate collagen and astaxanthin amounts.
How scoring works
Quantity:3 Ounce(s) • (27 servings)
Goals:
Skin Health
Anti-Aging
Joint Health

Score 80

A well-designed hydration and collagen blend uses clear forms and complementary actives, with moderate collagen and astaxanthin amounts.
How scoring works
$19.70($0.72 per serving)
Daily Vita
$ 19.70
Amazon
$ 24.22
iHerb
$ 0.00
Report prices

Analysis

The formula addresses hydration, structural protein, collagen formation, and antioxidant defense in one powder. Sodium hyaluronate reaches a useful 120 mg oral amount, making it the most convincingly dosed active.

Two grams of hydrolyzed fish collagen provide a modest but relevant contribution, and the declared protein supports label consistency. AstaReal supplies clearly identified astaxanthin, although 2 mg sits toward general rather than intensive antioxidant use.

The powder is a good fit for someone who wants a compact beauty and joint blend rather than a high-dose collagen-only product. Its combination is logical, but buyers needing a larger collagen serving would have to look elsewhere.

Who is it for
  • Adults seeking combined skin and joint support
  • People wanting hyaluronic acid with marine collagen
  • Users comfortable with a daily powder
Best for
  • Skin hydration support
  • Moderate marine collagen supplementation
  • Multi-pathway connective-tissue nutrition

Pros

  • Hyaluronic acid reaches a useful oral amount
  • Hydrolyzed fish collagen has a clear source
  • Vitamin C and branded astaxanthin add complementary support

Cons

  • Collagen amount is modest
  • Astaxanthin amount suits general support more than intensive use
  • Collagen type and peptide standard are not stated

Warnings

  • Fish collagen is unsuitable for people with a fish allergy.
  • Astaxanthin may add to the effects of blood-pressure-lowering medicines.
  • Vitamin C may cause stomach upset in sensitive users.

Nutrient quality

91 Highest impact

The formula uses appropriate forms across its main actives and avoids obviously aggressive dosing. Hyaluronic acid is especially well positioned, while collagen and astaxanthin serve as more moderate support.

.

Ingredient transparency

78 High impact

All actives carry specific amounts and no blend hides their doses. Collagen type, use directions, and inactive ingredients remain insufficiently described.

.

Customer satisfaction

64 Moderate impact

The average rating is positive, and the review volume is adequate for a useful signal. No review details were provided to identify common complaints or validate skin and joint experiences.

.

Value for money

84 Highest impact

The coherent multi-active design and useful hyaluronic acid dose broadly justify the cost. Moderate collagen and astaxanthin amounts prevent exceptional value, but the formula remains competitive.

.
Report analysis

Goals

Skin Health
Skin Health
Impact
Highest effect
A+ Goal FitA Strength of SupportA+ CoverageA+ Formula Quality
Hyaluronic Acid · 120 mgVitamin C · 100 mgCollagen · 2000 mgAstaxanthin · 2 mg

Hydrolyzed fish collagen, hyaluronic acid, and astaxanthin directly target structure, hydration, and oxidative defense. All three actives have human evidence relevant to elasticity, moisture, wrinkles, or photo-stress.

Hyaluronic acid reaches a preferred oral range, while collagen and astaxanthin provide useful supporting amounts. Hydrolyzed fish collagen, sodium hyaluronate, and branded astaxanthin are clearly disclosed, though collagen type is missing.

Study evidence
Astaxanthin Supportive 12 studies
Collagen Supportive 62 studies
Hyaluronic Acid Supportive 96 studies
Vitamin C Supportive 53 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitB+ Strength of SupportA- CoverageA+ Formula Quality
Astaxanthin · 2 mgCollagen · 2000 mg

Hydrolyzed fish collagen, hyaluronic acid, vitamin C, and astaxanthin form a targeted skin and connective-tissue aging formula. Hyaluronic acid is well dosed, while the collagen and astaxanthin amounts are more moderate than amounts often used for robust effects.

Each active is clearly disclosed, and vitamin C supports collagen formation while astaxanthin adds antioxidant protection. Fish-derived collagen creates a specific allergen concern for people with fish allergy.

Study evidence
Astaxanthin Supportive 4 studies
Collagen Supportive 33 studies
Hyaluronic Acid Supportive 76 studies
Vitamin C Supportive 30 studies
Joint Health
Joint Health
Impact
Highest effect
A Goal FitB Strength of SupportA- CoverageA+ Formula Quality
Collagen · 2000 mgHyaluronic Acid · 120 mg

Collagen, hyaluronic acid, vitamin C, and astaxanthin cover structural support, lubrication, synthesis, and antioxidant protection in a coherent joint formula. The breadth is unusually relevant because each ingredient has a distinct role.

Hyaluronic acid reaches a useful oral amount, while the collagen serving is modest and astaxanthin is suited more to general antioxidant support. Clear amounts and well-chosen forms strengthen confidence despite those dose limitations.

Study evidence
Astaxanthin Supportive 2 studies
Collagen Supportive 49 studies
Hyaluronic Acid Supportive 156 studies
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Protein
2 Gram(s)
Vitamin C (Sodium Ascorbate)
 100 mg
Collagen, Hydrolyzed, Powder (Fish)
 2000 mg
Hyaluronic Acid (Sodium Hyaluronate)
 120 mg
AstaReal (Astaxanthin, Powder)
 2 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Hyaluronic Acid (Sodium Hyaluronate) · 120 mg OverallScore77
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Sodium hyaluronate provides a stable oral form, though no low-molecular-weight processing is claimed. The amount reaches the preferred clinical range. The source is undisclosed despite clear amount labeling. The serving cost is reasonable for the amount supplied.

View ingredientView products
Astaxanthin (Astaxanthin, Powder) · 2 mg OverallScore62
C+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

A clearly identified natural algal source supports ingredient quality. The clearly stated active amount is suited to general antioxidant support. The low active amount produces poor astaxanthin-focused value.

View ingredientView products
Collagen (Fish) · 2000 mg OverallScore45
C+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Hydrolyzed fish collagen offers an absorbable form with a clear marine source, though the collagen type and branded peptide standard are not stated. The 2,000 mg amount is modest, but its matching 2 g protein declaration supports label accuracy. Value is middling, and people with fish allergy should avoid this fish-derived collagen.

View ingredientView products
Loading alternative details
83 Performance

High Potency Maxi-Collagen 7000

Country Life
<p>Seven grams of total collagen, including 2,500 mg Verisol peptides, plus vitamins A and C and biotin provide substantially deeper collagen support. Hyaluronic acid and astaxanthin are absent, and the serving cost is slightly higher.</p>
76 Performance

Grass Fed Collagen Super Beauty Blueberry Acai Flavor

Garden of Life
<p>Ten grams of collagen and 10 mg astaxanthin provide much higher amounts of two key beauty actives than the original. It lacks hyaluronic acid, costs more per serving, and uses a different collagen source.</p>
84 Performance

Bone Food Unflavored

California Gold Nutrition
<p>Five grams of hydrolyzed marine collagen with 60 mg sodium hyaluronate and vitamin C delivers a larger collagen dose while retaining hydration support. Added vitamin D, vitamin K, calcium, magnesium, and zinc shift part of the formula toward bone support.</p>
87 Budget

Collagen + C 2500 mg

Spring Valley
<p>Verisol collagen at 2,500 mg and vitamin C provide a slightly larger collagen dose at a much lower serving cost. It omits hyaluronic acid and astaxanthin, so the savings come with narrower skin and joint coverage.</p>
75 Budget

Collagen

youtheory men
<p>Five grams of hydrolyzed collagen plus vitamin C and biotin provide more collagen at a lower serving cost. Hyaluronic acid and astaxanthin are absent, while the added Fo-Ti extract has no clearly stated role in the supplied analysis.</p>
80 Budget

Maxi-Skin Collagen + C&A Powder Flavorless

Country Life
<p>Verisol collagen at 2,500 mg with vitamins A and C offers a focused skin formula at a lower serving cost. It lacks both hyaluronic acid and astaxanthin, making it less complete for the original’s hydration emphasis.</p>
79 Value

Hydration Rescue

NOW Solutions
<p>The same 120 mg sodium hyaluronate amount is available at a lower serving cost, making it a focused hydration value. Collagen falls to 200 mg and vitamin C and astaxanthin are absent, so it is not a complete replacement.</p>
84 Value

Tri-Layer Maxi-Skin Collagen + C & A

Country Life
<p>Verisol collagen rises to 2,500 mg with vitamins A and C while the serving cost remains similar. It leaves out hyaluronic acid and astaxanthin but offers more collagen for the money.</p>
66 Value

Hydrolyzed Collagen Powder Unflavored

Green Foods
<p>Hydrolyzed bovine types I and III collagen provide a simple collagen source at a lower serving cost. The disclosed collagen amount is lower than the original and the formula omits vitamin C, hyaluronic acid, and astaxanthin, so the benefit is mainly economy.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy and Safety of Topical or Oral Hydrolyzed Collagen in Women with Dermatoporosis: A Randomized, Double-Blind, Factorial Design Study.
    Guadanhim LRS; Miot HA; Soares JLM; Silva SAM; Leonardi GR; Lopes RD; Bagatin E · Dermatology and therapy · 2023
    Randomized trial56 participantsSkin Health forCollagen
  2. Exploring the Impact of Hydrolyzed Collagen Oral Supplementation on Skin Rejuvenation: A Systematic Review and Meta-Analysis.
    Dewi DAR; Arimuko A; Norawati L; Yenny SW; Setiasih NL; Perdiyana A; Arkania N; Nadhira F; Wiliantari N · Cureus · 2024
    Meta-analysis967 participants14 studies pooledSkin Health forCollagen
  3. Oral Supplementation of Low-Molecular-Weight Collagen Peptides Reduces Skin Wrinkles and Improves Biophysical Properties of Skin: A Randomized, Double-Blinded, Placebo-Controlled Study.
    Kim J; Lee SG; Lee J; Choi S; Suk J; Lee JH; Yang JH; Yang JS; Kim J · Journal of medicinal food · 2022
    Randomized trial100 participantsSkin Health forCollagen
  4. The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Wang Y; Zhu W; Luo W; Ma Y; Zhou Y · Journal of cosmetic dermatology · 2025
    Randomized trial77 participantsSkin Health forCollagen
  5. Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis.
    Pu SY; Huang YL; Pu CM; Kang YN; Hoang KD; Chen KH; Chen C · Nutrients · 2023
    Meta-analysis1,721 participants26 studies pooledSkin Health forCollagen
  6. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.
    Proksch E; Segger D; Degwert J; Schunck M; Zague V; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial69 participantsSkin Health Anti-Aging forCollagen
  7. Management and Amelioration of Knee Joint Osteoarthritis in Adults Using a Novel High-Functional Bovine Collagen Peptide as a Nutritional Therapy: A Double-Blind, Prospective, Multicentric, Randomized, Active and Placebo Controlled, Five-Arm, Clinical Study to Evaluate the Efficacy, Safety, and Tolerability.
    Devasia S; Joseph JT; P S S; Koizumi S; Clarke L; V T S; Kailas AP; Madhavan S · Cartilage · 2024
    Randomized trial100 participantsJoint Health forCollagen
  8. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.
    Proksch E; Schunck M; Zague V; Segger D; Degwert J; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial114 participantsSkin Health Anti-Aging forCollagen
  9. The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial.
    Zdzieblik D; Brame J; Oesser S; Gollhofer A; König D · Nutrients · 2021
    Randomized trial180 participantsJoint Health forCollagen
  10. Efficacy and safety of low-molecular-weight collagen peptides in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial.
    Park SY; Lee SH; Kim HT; Park HJ; Kim DU; Kim SU; Heo I · Frontiers in nutrition · 2025
    Randomized trial80 participantsJoint Health forCollagen
  11. [Efficacy and safety of undenatured type II collagen in patients with knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial].
    Alekseeva LI; Kashevarova NG; Taskina EA; Strebkova EA; Korotkova TA; Sharapova EP; Savushkina NM; Lila AM; Shostak NA; Mazurov VI; Nesterovich II; Dedkova VA; Vasilyuk VB; Egorova NV; Leontyeva MA; Yakupova SP; Vinogradova IB; Sorotskaya VN; Shirokova LY · Terapevticheskii arkhiv · 2024
    Randomized trial212 participantsJoint Health forCollagen
  12. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study.
    Kim DU; Chung HC; Choi J; Sakai Y; Lee BY · Nutrients · 2018
    Randomized trial64 participantsSkin Health forCollagen
  13. Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
    Danessa G; Notario D; Regina R · Indian journal of dermatology, venereology and leprology · 2025
    Meta-analysis646 participants10 studies pooledSkin Health forCollagen
  14. Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study.
    Lee M; Kim E; Ahn H; Son S; Lee H · Food & function · 2023
    Randomized trial100 participantsSkin Health Anti-Aging forCollagen
  15. Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double-blind, placebo-controlled trial.
    Luo C; Su W; Song Y; Srivastava S · Journal of experimental orthopaedics · 2023
    Randomized trial101 participantsJoint Health forCollagen
  16. Function of the normal meniscus and consequences of meniscal resection.
    Aagaard H; Verdonk R · Scandinavian journal of medicine & science in sports · 1999
    Narrative reviewJoint Health forCollagen
  17. Role of collagen hydrolysate in bone and joint disease.
    Moskowitz RW · Seminars in arthritis and rheumatism · 2001
    Narrative reviewJoint Health forCollagen
  18. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort.
    Benito-Ruiz P; Camacho-Zambrano MM; Carrillo-Arcentales JN; Mestanza-Peralta MA; Vallejo-Flores CA; Vargas-López SV; Villacís-Tamayo RA; Zurita-Gavilanes LA · International journal of food sciences and nutrition · 2012
    Randomized trial250 participantsJoint Health forCollagen
  19. [Experience with the use of undenatured type II collagen in patients with stage III knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial].
    Alekseeva LI; Kashevarova NG; Taskina EA; Strebkova EA; Korotkova TA; Sharapova EP; Savushkina NM; Lila AM; Shostak NA; Nesterovich II; Dedkova VA; Vasilyuk VB; Egorova NV; Leontyeva MA; Yakupova SP; Vinogradova IB; Sorotskaya VN; Shirokova LI; Rudakova AV · Terapevticheskii arkhiv · 2025
    Randomized trial50 participantsJoint Health forCollagen
  20. Increased urinary excretion of C-telopeptides of type II collagen (CTX-II) predicts cartilage loss over 21 months by MRI.
    Dam EB; Byrjalsen I; Karsdal MA; Qvist P; Christiansen C · Osteoarthritis and cartilage · 2009
    Cohort study158 participantsJoint Health forCollagen
  21. Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin.
    Petyaev IM; Klochkov VA; Chalyk NE; Pristensky DV; Chernyshova MP; Kyle NH; Bashmakov YK · The journal of nutrition, health & aging · 2019
    Randomized trial32 participantsAnti-Aging forAstaxanthin
  22. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.
    Phetcharat L; Wongsuphasawat K; Winther K · Clinical interventions in aging · 2016
    Randomized trial34 participantsAnti-Aging Skin Health forAstaxanthin
  23. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential.
    Kidd P · Alternative medicine review : a journal of clinical therapeutic · 2012
    Narrative reviewAnti-Aging forAstaxanthin
  24. Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing.
    Zhou X; Cao Q; Orfila C; Zhao J; Zhang L · Nutrients · 2021
    Meta-analysis11 studies pooledAnti-Aging forAstaxanthin
  25. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
    de Miranda RB; Weimer P; Rossi RC · International journal of dermatology · 2021
    Meta-analysis1,125 participants19 studies pooledAnti-Aging Skin Health forCollagen
  26. Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Lee E; Ahn DK; Kim JH; Lee S; Kim HJ; Lee HK; Shin JH · Journal of microbiology and biotechnology · 2025
    Randomized trial70 participantsAnti-Aging forCollagen
  27. Effectiveness and Safety of a Cross-linked Hyaluronic Acid Plus Mannitol Filler for the Correction of Nasolabial Folds in Chinese Subjects: A Randomized, Blinded, Controlled Study.
    Wu Y; Ascher B; Yang Z; Bi H; Li L; Zhao H; Wang H; Zhang J; Luo SK · Aesthetic surgery journal · 2026
    Randomized trial390 participantsAnti-Aging forHyaluronic Acid
  28. A hyaluronic acid-based micro-filler improves superficial wrinkles and skin quality: a randomized prospective controlled multicenter study.
    Fanian F; Deutsch JJ; Bousquet MT; Boisnic S; Andre P; Catoni I; Beilin G; Lemmel C; Taieb M; Gomel-Toledano M; Issa H; Garcia P · The Journal of dermatological treatment · 2023
    Randomized trial146 participantsAnti-Aging forHyaluronic Acid
  29. Safety and Effectiveness of a Crosslinked Hyaluronic Acid Filler in Korean Patients for the Correction of Nasolabial Folds: A Randomized, Patient- and Evaluator-Blinded, Paired Study.
    Lee SH; Park E; Won CH · Aesthetic surgery journal · 2026
    Randomized trial100 participantsAnti-Aging forHyaluronic Acid
  30. Safety and Efficacy of Hyaluronic Acid-Based Filler for Neck Wrinkles: A Prospective, Multicenter, Randomized, Parallel-Controlled Non-Inferiority Trial.
    Jiang M; Cheng H; Li Y; Ai H; Li J; Liang Y; Xu W · Clinical, cosmetic and investigational dermatology · 2026
    Randomized trial188 participantsAnti-Aging forHyaluronic Acid
  31. A randomized study showing improved skin quality and aesthetic appearance of dorsal hands after hyaluronic acid gel treatment in a Chinese population.
    Wu Y; Tian Y; Xu J; Zhong S; Wang R; Wu W · Journal of cosmetic dermatology · 2021
    Randomized trial100 participantsAnti-Aging forHyaluronic Acid
  32. Study on the Multiple Efficacies of Vitamin C Serum in Anti-Glycation, Anti-Carbonylation, Antioxidation, and Anti-Inflammation of Human Skin Based on In Vivo Tests.
    Zi Y; Liu J; Liu Q; Pan Y; Jiang X · Journal of cosmetic dermatology · 2026
    Randomized trial66 participantsAnti-Aging forVitamin C
  33. Evaluation of the anti-wrinkle effect of a lipophilic pro-vitamin C derivative, tetra-isopalmitoyl ascorbic acid.
    Yokota M; Yahagi S · Journal of cosmetic dermatology · 2022
    Randomized trial69 participantsAnti-Aging forVitamin C
  34. The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach.
    Crisan D; Roman I; Crisan M; Scharffetter-Kochanek K; Badea R · Clinical, cosmetic and investigational dermatology · 2015
    Clinical trial60 participantsAnti-Aging forVitamin C
  35. In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound.
    Vergilio MM; Aiello LM; Furlan AS; Caritá AC; Azevedo JR; Bolzinger MA; Chevalier Y; Leonardi GR · Journal of cosmetic dermatology · 2022
    Randomized trial25 participantsAnti-Aging forVitamin C
  36. Clinical Applications of Vitamin C in Dermatology: A Systematic Review.
    Boghosian T; Mendez H; Boghosian N; Sayegh M; Beer J; Tosti A · The Journal of clinical and aesthetic dermatology · 2026
    Systematic review44 studies pooledAnti-Aging forVitamin C
  37. Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial.
    Grigorian A; Tabatabaeyan A; Salesi M; Feizi A; Ahmadi AR; Kafeshani M · Food & function · 2025
    Randomized trial60 participantsJoint Health forAstaxanthin
  38. A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.
    Hill WS; Dohnalek MH; Ha Y; Kim SJ; Jung JC; Kang SB · Nutrients · 2023
    Randomized trial100 participantsJoint Health forAstaxanthin
  39. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
    Lugo JP; Saiyed ZM; Lane NE · Nutrition journal · 2016
    Randomized trial191 participantsJoint Health forCollagen
  40. Oral Hyaluronic Acid in Osteoarthritis and Low Back Pain: A Systematic Review.
    de Carvalho JF; Davidson J · Mediterranean journal of rheumatology · 2025
    Systematic review597 participants11 studies pooledJoint Health forHyaluronic Acid
  41. Single intra-articular injection of lightly cross-linked hyaluronic acid reduces knee pain in symptomatic knee osteoarthritis: a multicenter, double-blind, randomized, placebo-controlled trial.
    Petterson SC; Plancher KD · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Randomized trial369 participantsJoint Health forHyaluronic Acid
  42. High molecular weight sodium hyaluronate (hyalectin) in osteoarthritis of the knee: a 1 year placebo-controlled trial.
    Dougados M; Nguyen M; Listrat V; Amor B · Osteoarthritis and cartilage · 1996
    Randomized trial110 participantsJoint Health forHyaluronic Acid
  43. Intra-articular hyaluronic acid compared with corticoid injections for the treatment of rhizarthrosis.
    Fuchs S; Mönikes R; Wohlmeiner A; Heyse T · Osteoarthritis and cartilage · 2006
    Randomized trial56 participantsJoint Health forHyaluronic Acid
  44. Platelet-rich plasma versus hyaluronic acid injection following arthrocentesis for temporomandibular joint disorders under sedation: a comparative clinical study.
    Mahdi MS; Abdulsattar MS · Oral and maxillofacial surgery · 2026
    Randomized trial60 participantsJoint Health forHyaluronic Acid
  45. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsJoint Health forVitamin C
  46. Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty.
    Han G; Ye Y; Kang P · Drug design, development and therapy · 2025
    Randomized trial100 participantsJoint Health forVitamin C
  47. Osteoarthritis prevalence and modifiable factors: a population study.
    Plotnikoff R; Karunamuni N; Lytvyak E; Penfold C; Schopflocher D; Imayama I; Johnson ST; Raine K · BMC public health · 2016
    Cross-sectional study4,733 participantsJoint Health forVitamin C
  48. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial.
    Ramón R; Holguín E; Chiriboga JD; Rubio N; Ballesteros C; Ezechieli M · Journal of personalized medicine · 2023
    Randomized trial110 participantsJoint Health forVitamin C
  49. Musculoskeletal manifestations of scurvy.
    Fain O · Joint bone spine · 2005
    Narrative reviewJoint Health forVitamin C
  50. The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial.
    Ito N; Seki S; Ueda F · Nutrients · 2018
    Randomized trial23 participantsSkin Health forAstaxanthin
  51. Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo.
    Yoon HS; Cho HH; Cho S; Lee SR; Shin MH; Chung JH · Journal of medicinal food · 2015
    Randomized trial44 participantsSkin Health forAstaxanthin
  52. Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers.
    Chalyk NE; Klochkov VA; Bandaletova TY; Kyle NH; Petyaev IM · Nutrition research (New York, N.Y.) · 2018
    Single-arm trial31 participantsSkin Health forAstaxanthin
  53. Cosmetic benefits of astaxanthin on humans subjects.
    Tominaga K; Hongo N; Karato M; Yamashita E · Acta biochimica Polonica · 2012
    Other66 participantsSkin Health forAstaxanthin
  54. Efficacy and Safety of Sodium Hyaluronate Gel for Facial Skin Rejuvenation.
    Liao Z; Hong W; Wang S; Hou Y; Lu S; Chen R; Zhang Y; Chen J; Liu Y; Luo S · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2026
    Randomized trial420 participantsSkin Health forHyaluronic Acid
  55. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study.
    Hsu TF; Su ZR; Hsieh YH; Wang MF; Oe M; Matsuoka R; Masuda Y · Nutrients · 2021
    Randomized trial40 participantsSkin Health forHyaluronic Acid
  56. Safety and efficacy of hyaluronic acid injectable filler in the treatment of nasolabial fold wrinkle: a randomized, double-blind, self-controlled clinical trial.
    Li XZ; Chiang CF; Lin YH; Chen TM; Wang CH; Tzeng YS; Cui HY · The Journal of dermatological treatment · 2023
    Randomized trial95 participantsSkin Health forHyaluronic Acid
  57. A Split-Face Study of the Effects of a Stabilized Hyaluronic Acid-Based Gel of Nonanimal Origin for Facial Skin Rejuvenation Using a Stamp-Type Multineedle Injector: A Randomized Clinical Trial.
    Roh NK; Kim MJ; Lee YW; Choe YB; Ahn KJ · Plastic and reconstructive surgery · 2016
    Randomized trial25 participantsSkin Health forHyaluronic Acid
  58. Long-term Safety and Effectiveness of Cold-Crosslinked Hyaluronic Acid Fillers: Multicenter, Randomized, Controlled, Double-Blind Study.
    Kaminer MS; Avelar RL; Baumann L; Callender V; Dayan SH; Green JB; Grekin SK; Guyon S · Aesthetic surgery journal · 2025
    Randomized trial140 participantsSkin Health forHyaluronic Acid
  59. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  60. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  61. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  62. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  63. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C