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5-HTP 5-Hydroxytryptophan 50 mg

Natural Factors Stress-Relax
4.6
★ ★ ★ ★ ★
(359 ratings)
5-HTP 50 mg
Product Image
Score90

A gentle 50 mg 5-HTP tablet for flexible and mild neurotransmitter support.

How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Stress Relief
Sleep Support
Mood Support

Score 90

A gentle 50 mg 5-HTP tablet for flexible and mild neurotransmitter support.

How scoring works

Also available as

2 options
100 mg • 120 Tablet(s) servings 5-HTP 100 mg • 120 Tablet(s) • 120 servings $32.19 ($0.26 per serving) 100 mg • 60 Tablet(s) servings 5-HTP 100 mg • 60 Tablet(s) • 60 servings $19.29 ($0.32 per serving)
$13.97($0.23 per serving)
Vitacost
$ 19.95
iHerb
$ 13.97
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Analysis

A 50 mg dose can be a perfect 'top-up' for your serotonin levels without being overwhelming. The tablet format is easy to take, and the inclusion of a small amount of calcium helps with the structure of the supplement.

This is a practical choice for individuals who may be sensitive to higher doses of amino acid precursors. It allows for gentle support of emotional balance and a more regulated sleep-wake cycle.

Pros

  • Flexible 50 mg dose
  • Includes a small amount of calcium
  • Natural botanical origin
  • Trusted brand for relaxation

Cons

  • Lower dose might be insufficient for some
  • Tablet format contains binders

Warnings

  • May cause mild sleepiness
  • Monitor for any digestive changes

Nutrient quality

86 Highest impact

Standardized botanical extracts provide the active precursor in a well-regarded and reliable form. The 50 mg dose offers a conservative approach to supplementation, which is ideal for those assessing individual tolerance.

Ingredient transparency

98 Highest impact

Labeling clearly identifies the dose and natural origin of the active ingredient with no proprietary mixtures used. Precise component naming and clear usage directions ensure a high level of transparency for the consumer.

Customer satisfaction

88 Highest impact

Consistent consumer ratings suggest solid satisfaction with the quality and effectiveness of the 50 mg dose. Feedback confirms that the results consistently align with the intended purpose of emotional and sleep support.

Value for money

87 Highest impact

The cost per serving is reasonable for a gentle 50 mg dose from a well-established and trusted brand. It offers solid value for individuals prioritizing safety and a starting-level approach to serotonin support.

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Goals

Stress Relief
Impact
Highest effect
A- Goal FitB- Strength of SupportC CoverageA+ Formula Quality

Provides 50 mg of 5-HTP derived from Griffonia simplicifolia as a gentle starting dose for mood and stress support. Serotonin synthesis is critical for emotional resilience and evening relaxation.

While the 50 mg dose is supportive, it falls on the lower end of the clinical therapeutic range for many adults. The formula is straightforward and offers a clean, single-ingredient option for those new to 5-HTP supplementation.

View goal →
Sleep Support
Impact
High effect
B+ Goal FitB- Strength of SupportB- CoverageA+ Formula Quality

5-HTP is provided in a 50mg dose to support the precursor pathway to serotonin and melatonin.

Starting with a lower dose may contribute to a safer transition for those new to using sleep-supportive precursors.

View goal →
Mood Support
Impact
High effect
A- Goal FitC+ Strength of SupportC CoverageA+ Formula Quality

5-HTP (50mg) derived from Griffonia simplicifolia.

This lower-dose serotonin precursor is suitable for individuals beginning support for emotional balance and stress resilience.

View goal →

Ingredients

IngredientAmount per serving
Calcium (Dicalcium Phosphate)
 35 mg
5-Hydroxytryptophan (Griffonia simplicifolia)
 50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
5-HTP (Griffonia simplicifolia) · 50 mg OverallScore65
C+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
This lower-dose 5-HTP option is ideal for individuals who are new to the supplement and wish to start with a conservative 50mg serving. It provides a natural source of the compound to support emotional balance and relaxation throughout the day.
View ingredientView products
96 Value

5-HTP 100 mg Extra Strength

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Moving up to a 100 mg dose at a similar price point provides better value for those who find the 50 mg concentration insufficient. It is highly effective for promoting evening tranquility and emotional balance.
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96 Value

5-HTP 100 mg

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Selecting a high-volume 120-count bottle of the standard 100 mg dose maximizes daily value and utility. It provides reliable, clinically-relevant support for psychological stability and evening sleep.
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96 Value

5-HTP 100 mg

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5-HTP Enhanced with Vitamins B6 and C

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Advanced Sleep Melatonin + 5-HTP Time Release

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5-HTP Plus+ 200 mg

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94 Budget

5-HTP 50 mg

NOW
4.7
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Selecting this larger 90-count bottle of the same 50 mg dose provides immediate savings per capsule. It is an ideal way to maintain a consistent starting dose of 5-HTP while staying on a budget.
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5-HTP 50 mg

NOW
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(14177 ratings)
Opting for the 180-count bulk format offers the best long-term economy for individuals using a moderate dose. This ensures a consistent supply of neurotransmitter precursors for half a year.
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93 Budget

5-HTP 50 mg

Swanson Premium Brand
4.6
★★★★★
(923 ratings)
This highly-rated alternative offers a gentle 50 mg dose in an affordable capsule format. It is a practical and budget-conscious way to support the body's natural serotonin synthesis.
Other sellers (1)
96 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
★★★★★
(7340 ratings)
Moving up to a 100 mg dose at a similar price point provides better value for those who find the 50 mg concentration insufficient. It is highly effective for promoting evening tranquility and emotional balance.
Other sellers (2)
96 Value

5-HTP 100 mg

NOW
4.7
★★★★★
(52220 ratings)
Selecting a high-volume 120-count bottle of the standard 100 mg dose maximizes daily value and utility. It provides reliable, clinically-relevant support for psychological stability and evening sleep.
Other sellers (4)
96 Value

5-HTP 100 mg

Doctor's Best
4.7
★★★★★
(13025 ratings)
This 180-count bottle of 100 mg capsules provides excellent longevity and cost-per-serving. It is more effective for individuals who find a low concentration insufficient for consistent daily results.
Other sellers (2)
96 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
4.8
★★★★★
(5550 ratings)
Adding critical metabolic cofactors like Vitamin B6 and C helps the body's synthesis pathways function better than the amino acid alone. The 100 mg concentration offers more robust support for mood and rest.
Other sellers (3)
92 Performance

Advanced Sleep Melatonin + 5-HTP Time Release

Natrol
4.5
★★★★★
(8510 ratings)
Employing time-release technology ensures that the 5-HTP is delivered steadily throughout the night for better sleep continuity. The addition of Vitamin B6 further facilitates neurotransmitter production.
Other sellers (3)
94 Performance

5-HTP Plus+ 200 mg

NatureWise
4.5
★★★★★
(5703 ratings)
Combining high-potency 200 mg 5-HTP with active Pyridoxal 5-Phosphate (P-5-P) offers significantly more potent assistance for mood and rest. The bioactive form of B6 ensures faster biological utilization.
Other sellers (4)
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