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Neuro Fuel

NS Natural Stacks
4.6
★ ★ ★ ★ ★
(104 ratings)
Phenylalanine 500 mg
Acetyl L-Carnitine 750 mg
Product Image
Score72
ALCAR and phenylalanine provide purposeful cognitive-energy support. Very high cost and important PKU, blood-pressure, and bleeding precautions limit its appeal.
How scoring works
Quantity:45 Capsule(s) • (15 servings)
Goals:
Energy
Brain Health
Mental Focus
Productivity Boost
Cognitive Support
Anti-Aging
Metabolism Boost
Weight Loss

Score 72

ALCAR and phenylalanine provide purposeful cognitive-energy support. Very high cost and important PKU, blood-pressure, and bleeding precautions limit its appeal.
How scoring works
$29.95($1.99 per serving)
iHerb
$ 29.95
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Analysis

Acetyl-L-carnitine HCl at 750 mg supports brain and cellular energy, while 500 mg L-phenylalanine supplies a neurotransmitter precursor. P5P at 5 mg provides a relevant metabolic cofactor.

Artichoke cynarin and forskolin add a secondary signaling concept, though evidence for the full combination is less established. The stack fits focus and productivity better than sustainable weight loss.

All actives are clearly quantified in a three-capsule serving. Only 15 servings and a high serving cost make it poor value compared with similar formulas.

Who is it for
  • Adults seeking a focused nootropic stack
  • People wanting ALCAR with phenylalanine
  • Users less sensitive to high serving cost
Best for
  • Mental energy
  • Productivity
  • Focus support

Pros

  • Provides 750 mg ALCAR HCl
  • Includes 500 mg L-phenylalanine
  • Uses active P5P
  • Discloses botanical markers

Cons

  • Only 15 servings
  • Very high serving cost
  • ALCAR purity assurance is absent
  • Limited direct weight-loss evidence

Warnings

  • People with phenylketonuria must not use phenylalanine
  • Phenylalanine can interact with MAO inhibitors
  • Forskolin may lower blood pressure
  • Forskolin may increase bleeding tendency with anticoagulants or antiplatelet medicines

Nutrient quality

86 Highest impact

Pyridoxal phosphate, marker-standardized artichoke, and acetyl-L-carnitine hydrochloride provide strong form detail. Artichoke, acetyl-L-carnitine, and phenylalanine are meaningful, while forskolin is a smaller support.

.

Ingredient transparency

82 Highest impact

Active amounts are stated and no proprietary blend hides a core dose. Missing excipient details and complete use directions leave the supplied label information incomplete.

.

Customer satisfaction

61 Moderate impact

The supplied aggregate satisfaction average provides a broad signal, while the response volume determines how stable it appears. No comment-level evidence is available to assess repeated complaints or confirm intended-use experiences.

.

Value for money

53 Moderate impact

Quality, safety trade-offs, or serving economics materially weaken value. The formula is focused and its supporting ingredients have plausible nootropic roles.

.
Report analysis

Goals

Energy
Energy
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC CoverageB+ Formula Quality
Acetyl L-Carnitine · 750 mg

Acetyl L-Carnitine provides relevant support for energy. Acetyl L-Carnitine contributes to physiological processes relevant to energy.

The formula supplies clearly identified ALCAR HCl at a useful standard-range amount. The high serving cost produces poor ALCAR efficiency, and the companion ingredients do not qualify for a premium value adjustment.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Brain Health
Brain Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB CoverageA- Formula Quality
Vitamin B6 · 5 mg

Acetyl-L-carnitine, phenylalanine, active B6, and forskolin create a targeted cognitive-energy and neurotransmitter formula. The two main amino-acid-related actives are clearly identified at useful amounts, supporting alertness and mental performance under demand.

Purity and manufacturing standards are not disclosed, and the formula lacks direct structural brain support. Phenylalanine is unsuitable for people with phenylketonuria, yet the supplied label details do not show that warning.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Phenylalanine Adverse 77 studies
Mental Focus
Mental Focus
Impact
Highest effect
B Goal FitA- Strength of SupportB CoverageB+ Formula Quality
Vitamin B6 · 5 mgAcetyl L-Carnitine · 750 mg

Acetyl-L-carnitine, L-phenylalanine, and active vitamin B6 create a focused stack for brain energy and neurotransmitter production. Their disclosed amounts are meaningful, while forskolin and artichoke extract add a secondary signaling strategy.

Evidence is strongest for the core nutrient mechanisms and less certain for the full combined nootropic effect. People with phenylketonuria must avoid the L-phenylalanine in this formula because they cannot safely metabolize that amino acid.

Study evidence
Acetyl L-Carnitine Supportive 7 studies
Phenylalanine No effect 7 studies
Vitamin B6 Disputed 6 studies
Productivity Boost
Productivity Boost
Impact
Highest effect
B Goal FitB+ Strength of SupportB+ CoverageB+ Formula Quality
Vitamin B6 · 5 mgAcetyl L-Carnitine · 750 mgAcetyl L-Carnitine · 750 mg

Acetyl-L-carnitine and phenylalanine directly support brain energy and catecholamine production, giving the formula a credible productivity focus. Active vitamin B6 adds a relevant cofactor, while artichoke and forskolin target a secondary signaling pathway with less direct performance evidence.

The main amounts are substantial and fully disclosed. Forskolin may lower blood pressure and can affect bleeding, so people using antihypertensive, anticoagulant, or antiplatelet medicines need clinical guidance.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Acetyl L-Carnitine Supportive 1 study
Vitamin B6 Disputed 6 studies
Cognitive Support
Cognitive Support
Impact
High effect
B- Goal FitB Strength of SupportB CoverageB Formula Quality
Vitamin B6 · 5 mgAcetyl L-Carnitine · 750 mg

Acetyl-L-carnitine, phenylalanine, P5P, and forskolin target mitochondrial energy and neurotransmitter support. The main actives are disclosed at useful amounts, although the artichoke-forskolin strategy has less direct cognitive evidence.

The formula covers energy, catecholamine precursors, and signaling pathways with reasonable depth. It is purposefully built, but stronger standardization and purity details would improve confidence.

Study evidence
Acetyl L-Carnitine Supportive 20 studies
Anti-Aging
Anti-Aging
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageB Formula Quality

A useful 750 mg acetyl-L-carnitine amount directly supports mitochondrial energy and may help preserve cognitive function with age. Artichoke and vitamin B6 add metabolic context, while phenylalanine supports neurotransmitter production.

The formula does not cover several other major longevity pathways such as glycation defense or broad inflammatory control. Coleus is lightly dosed, and source or purity assurance for acetyl-L-carnitine is not provided.

Study evidence
Acetyl L-Carnitine Supportive 1 study

Ingredients

IngredientAmount per serving
Vitamin B-6 (Pyridoxal 5-Phosphate)
 5 mg
Artichoke Leaf Extract (Cynarin)
 900 mg
Acetyl-L-Carnitine (Acetyl-L-Carnitine HCl)
 750 mg
L-Phenylalanine
500 mg
Coleus forskohlii Root Extract (Forskolin)
 20 mg
Adults 18–50 Women
Report overview
Phenylalanine · 500 mg OverallScore82
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

A targeted nootropic formula supplies a full 500 mg of clearly identified L-phenylalanine without competing protein or BCAAs. P5P and forskolin add relevant formula value, although the cost for the active amount remains high. The supplied label details lack a PKU warning, an important omission for people with phenylketonuria.

View ingredientView products
Acetyl L-Carnitine (Acetyl-L-Carnitine HCl) · 750 mg OverallScore75
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The formula supplies clearly identified ALCAR HCl at a useful standard-range amount. Its exact dose is fully disclosed, though no manufacturing or purity assurance is supplied. The high serving cost produces poor ALCAR efficiency, and the companion ingredients do not qualify for a premium value adjustment.

View ingredientView products
Loading alternative details
73 Performance

Vital Brain Powder

Vital Nutrients
<p>Acetyl-L-carnitine, glycerophosphocholine, and phosphatidylserine provide more direct cognitive membrane and neurotransmitter support than the original's artichoke and forskolin components. The carnitine amount is also slightly higher, but the serving cost is high and phenylalanine is absent.</p>
81 Performance

CoQ10 + Alpha Lipoic Acid + Acetyl L-Carnitine HCl

Nature's Lab
<p>Acetyl-L-carnitine, CoQ10, and alpha-lipoic acid create a more focused mitochondrial and antioxidant combination than the original. The formula omits phenylalanine and the artichoke-forskolin pair, while alpha-lipoic acid may compound glucose-lowering medicines.</p>
82 Performance

Optimized Carnitine

Life Extension
<p>Three specific carnitine forms provide broader mitochondrial and circulation support at a higher total carnitine amount than the original. The dose is aggressive for routine use, and the formula does not retain phenylalanine, artichoke, forskolin, or vitamin B6.</p>
87 Budget

Acetyl L-Carnitine 500 mg

Swanson
<p>A much lower serving cost retains acetyl-L-carnitine hydrochloride in a simple, clearly dosed formula. The amount is lower than the original and it omits phenylalanine, artichoke, forskolin, and vitamin B6, so it suits focused carnitine use rather than a complete nootropic stack.</p>
87 Budget

L-Phenylalanine 500 mg

NOW
<p>A much lower serving cost matches the original's phenylalanine amount without unrelated additions. It leaves out acetyl-L-carnitine and the other nootropic ingredients, and people with phenylketonuria should avoid supplemental phenylalanine.</p>
86 Budget

Acetyl L-Carnitine 500 mg

Source Naturals
<p>A substantially lower serving cost provides a clear acetyl-L-carnitine hydrochloride dose for energy and cognitive support. The focused design is easier to assess than the original blend, but it supplies less carnitine and omits phenylalanine, artichoke, forskolin, and vitamin B6.</p>
84 Value

Acetyl L-Carnitine & Alpha-Lipoic Acid

Source Naturals
<p>A lower serving cost combines acetyl-L-carnitine with a meaningful alpha-lipoic acid amount, improving mitochondrial and antioxidant breadth. It provides less carnitine than the original and omits phenylalanine, artichoke, forskolin, and active vitamin B6; alpha-lipoic acid may also lower blood sugar alongside medicines.</p>
84 Value

Acetyl-L-Carnitine Arginate

Life Extension
<p>Two clearly identified acetyl-L-carnitine salts provide a substantial focused serving at much better recurring value than the original. The total carnitine amount is somewhat lower, and the simpler design does not include phenylalanine or the original botanical pathways.</p>
86 Value

Acetyl-L-Carnitine 500 mg

The Vitamin Shoppe
<p>A much lower serving cost preserves a clearly identified acetyl-L-carnitine hydrochloride dose without extra ingredients. It is a better-value choice for focused carnitine use, though the amount is lower and the original's phenylalanine, botanicals, and active vitamin B6 are absent.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsCognitive Support Brain Health forAcetyl L-Carnitine
  2. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  3. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsEnergy forAcetyl L-Carnitine
  4. Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach.
    Brooks JO; Yesavage JA; Carta A; Bravi D · International psychogeriatrics · 1998
    Randomized trial334 participantsCognitive Support forAcetyl L-Carnitine
  5. A 1-year controlled trial of acetyl-l-carnitine in early-onset AD.
    Thal LJ; Calvani M; Amato A; Carta A · Neurology · 2000
    Randomized trial229 participantsCognitive Support forAcetyl L-Carnitine
  6. Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia.
    Rai G; Wright G; Scott L; Beston B; Rest J; Exton-Smith AN · Current medical research and opinion · 1990
    Randomized trial36 participantsBrain Health forAcetyl L-Carnitine
  7. Carnitine for fatigue in multiple sclerosis.
    Tejani AM; Wasdell M; Spiwak R; Rowell G; Nathwani S · The Cochrane database of systematic reviews · 2012
    Systematic review1 studies pooledEnergy forAcetyl L-Carnitine
  8. Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine.
    Passeri M; Iannuccelli M; Ciotti G; Bonati PA; Nolfe G; Cucinotta D · International journal of clinical pharmacology research · 1989
    Randomized trial30 participantsBrain Health forAcetyl L-Carnitine
  9. Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients.
    Rossini M; Di Munno O; Valentini G; Bianchi G; Biasi G; Cacace E; Malesci D; La Montagna G; Viapiana O; Adami S · Clinical and experimental rheumatology · 2007
    Randomized trial102 participantsEnergy forAcetyl L-Carnitine
  10. The Effect of Acylcarnitines on Cognitive Function: A Two-Sample Mendelian Randomization Study.
    Luan S; Zhang J; Wang C; Wang Z; Zhou J · Brain and behavior · 2025
    OtherBrain Health forAcetyl L-Carnitine
  11. Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort.
    Montanari S; Jansen R; Schranner D; Kastenmüller G; Arnold M; Janiri D; Sani G; Bhattacharyya S; Mahmoudian Dehkordi S; Dunlop BW; Rush AJ; Penninx BWHJ; Kaddurah-Daouk R; Milaneschi Y · Translational psychiatry · 2025
    Cohort study2,574 participantsEnergy forAcetyl L-Carnitine
  12. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsAnti-Aging forAcetyl L-Carnitine
  13. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  14. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  15. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  16. The Association between Dietary Amino Acid Intake and Cognitive Decline 8 Years Later in Japanese Community-Dwelling Older Adults.
    Kinoshita K; Otsuka R; Takada M; Tsukamoto-Yasui M; Nishita Y; Tange C; Tomida M; Shimokata H; Kuzuya M; Imaizumi A; Arai H · The journal of nutrition, health & aging · 2021
    Cohort study427 participantsBrain Health forPhenylalanine
  17. Magnetic resonance imaging in phenylketonuria: reversal of cerebral white matter change.
    Cleary MA; Walter JH; Wraith JE; White F; Tyler K; Jenkins JP · The Journal of pediatrics · 1995
    Non-randomized trial41 participantsBrain Health forPhenylalanine
  18. [Cross-sectional association between the amino acid intake and episodic memory in middle- and old-aged community dwellers].
    Kinoshita K; Otsuka R; Takada M; Tsukamoto-Yasui M; Nishita Y; Tange C; Tomida M; Shimokata H; Imaizumi A; Arai H · Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics · 2021
    Cross-sectional study2,082 participantsBrain Health forPhenylalanine
  19. Improved dietary control results in improvements in indices of white matter structure in adults with phenylketonuria: the ReDAPT study.
    Kang MJY; Adamson C; Malpas CB; Winton-Brown T; Burgess N; Fazio T; Velakoulis D; Desmond P; Venkatraman V; De Jong G; Walterfang M · Acta neuropsychiatrica · 2026
    Single-arm trial7 participantsBrain Health forPhenylalanine
  20. [Brain white matter lesions of children with phenylketonuria before and after treatment].
    Wang ZX; Zhou ZS; Yu WM · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2006
    Single-arm trial19 participantsBrain Health forPhenylalanine
  21. A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
    Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
    Randomized trial63 participantsCognitive Support forAcetyl L-Carnitine
  22. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
    Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
    Randomized trial96 participantsCognitive Support forAcetyl L-Carnitine
  23. The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
    Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  24. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
    Randomized trial67 participantsEnergy forAcetyl L-Carnitine
  25. A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
    Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
    Randomized trial239 participantsEnergy forAcetyl L-Carnitine
  26. Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
    Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
    Systematic reviewEnergy forAcetyl L-Carnitine
  27. Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
    Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
    Randomized trial62 participantsMental Focus Productivity Boost forAcetyl L-Carnitine
  28. [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
    Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
    Non-randomized trial17 participantsMental Focus forAcetyl L-Carnitine
  29. Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
    Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
    Randomized trial112 participantsMental Focus forAcetyl L-Carnitine
  30. Acetyl-L-carnitine for patients with hepatic encephalopathy.
    Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
    Meta-analysis398 participants5 studies pooledMental Focus forAcetyl L-Carnitine
  31. Cognition after a 4-week high phenylalanine intake in adults with phenylketonuria - a randomized controlled trial.
    Trepp R; Muri R; Maissen-Abgottspon S; Haynes AG; Hochuli M; Everts R · The American journal of clinical nutrition · 2024
    Randomized trial30 participantsMental Focus forPhenylalanine
  32. A systematic review of cognitive functioning in early treated adults with phenylketonuria.
    Hofman DL; Champ CL; Lawton CL; Henderson M; Dye L · Orphanet journal of rare diseases · 2019
    Systematic review16 studies pooledMental Focus forPhenylalanine
  33. Are Functional Brain Networks Sensitive to High Phenylalanine in Adults With Phenylketonuria?
    Vallesi V; Morishima Y; Winiger L; Trepp R; Everts R; Muri R · JIMD reports · 2026
    Randomized trial23 participantsMental Focus forPhenylalanine
  34. Sustained attention in untreated non-PKU-hyperphenylalaninemia.
    Weglage J; Schmidt E; Fünders B; Pietsch M; Ullrich K · Journal of clinical and experimental neuropsychology · 1997
    Case-control study48 participantsMental Focus forPhenylalanine
  35. Effects of L-histidine depletion and L-tyrosine/L-phenylalanine depletion on sensory and motor processes in healthy volunteers.
    van Ruitenbeek P; Sambeth A; Vermeeren A; Young SN; Riedel WJ · British journal of pharmacology · 2009
    Clinical trial17 participantsMental Focus forPhenylalanine
  36. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.
    Deijen JB; van der Beek EJ; Orlebeke JF; van den Berg H · Psychopharmacology · 1995
    Randomized trial76 participantsMental Focus forVitamin B6
  37. The effect of vitamin B6 on cognition.
    Malouf R; Grimley Evans J · The Cochrane database of systematic reviews · 2004
    Systematic review109 participants2 studies pooledMental Focus forVitamin B6
  38. Antiemetic use during pregnancy and child neurodevelopment: population-based birth cohort study.
    Cho Y; Choi EY; Han JY; Kim H; Choe YJ; Shin JY · BMC medicine · 2025
    Cohort study630,904 participantsMental Focus forVitamin B6
  39. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
    Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
    Randomized trial44 participantsMental Focus Productivity Boost forVitamin B6
  40. B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial
    Tammy M Scott, Graham Rogers, Daniel E Weiner, Kathryn Livingston, Jacob Selhub, Paul F Jacques, Irwin H Rosenberg, Aron M Troen · The Journal of Prevention of Alzheimer's Disease · 2017
    Randomized trial584 participantsMental Focus forVitamin B6
  41. Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
    Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
    Randomized trialMetabolism Boost forAcetyl L-Carnitine
  42. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  43. Dietary one-carbon metabolism nutrients and risk of MASLD progression: a prospective cohort study.
    Shen L; Wang K; Li R; Li Y; Guo Y; Li F; Yuan J; Yang Z; Xia B; Lin X · European journal of clinical nutrition · 2026
    Cohort study46,800 participantsMetabolism Boost forVitamin B6
  44. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
    Kim H; Enrione EB; Narayanan V; Li T; Campa A · Nutrients · 2022
    Cross-sectional study461 participantsMetabolism Boost forVitamin B6
  45. Influence of oral contraceptives, pyridoxine (vitamin B6), and tryptophan on carbohydrate metabolism.
    Adams PW; Wynn V; Folkard J; Seed M · Lancet (London, England) · 1976
    Clinical trial46 participantsMetabolism Boost forVitamin B6
  46. Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
    Rose DP; Leklem JE; Brown RR; Linkswiler HM · The American journal of clinical nutrition · 1975
    Clinical trialMetabolism Boost forVitamin B6
  47. Vitamin B6, B9, and B12 Intakes and Cognitive Performance in Elders: National Health and Nutrition Examination Survey, 2011-2014.
    Xu H; Wang S; Gao F; Li C · Neuropsychiatric disease and treatment · 2022
    Cross-sectional study2,421 participantsProductivity Boost forVitamin B6
  48. Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults.
    Coburn SP; Schaltenbrand WE; Mahuren JD; Clausman RJ; Townsend D · The American journal of clinical nutrition · 1983
    Non-randomized trialProductivity Boost forVitamin B6
  49. Identifying Key Predictors of Cognitive Dysfunction in Older People Using Supervised Machine Learning Techniques: Observational Study.
    Rankin D; Black M; Flanagan B; Hughes CF; Moore A; Hoey L; Wallace J; Gill C; Carlin P; Molloy AM; Cunningham C; McNulty H · JMIR medical informatics · 2024
    Cohort studyProductivity Boost forVitamin B6
  50. Inappropriate nutrients intake is associated with lower functional status and inferior quality of life in older adults with depression.
    Guligowska A; Pigłowska M; Fife E; Kostka J; Sołtysik BK; Kroc Ł; Kostka T · Clinical interventions in aging · 2017
    Case-control study49 participantsProductivity Boost forVitamin B6