Product Image

Qualia Mind

Neurohacker Collective
4.5
★ ★ ★ ★ ★
(48 ratings)
Theobromine 100 mg
Theanine 200 mg
Acetyl L-Carnitine 500 mg
Rhodiola
Taurine 200 mg
Alpha-GPC 200 mg
Ginkgo
Product Image
Score58
A deep nootropic stack is well aligned with daytime focus, mental energy, and stress-related cognitive fatigue. High capsule burden, several underdosed supporting ingredients, and a complex interaction profile limit its practicality.
How scoring works
Quantity:105 Capsule(s) • (15 servings)
Goals:
Energy
Mental Focus
Mood Support
Cognitive Support
Brain Health
Productivity Boost
Anti-Aging
Stress Relief
Metabolism Boost
Weight Loss

Score 58

A deep nootropic stack is well aligned with daytime focus, mental energy, and stress-related cognitive fatigue. High capsule burden, several underdosed supporting ingredients, and a complex interaction profile limit its practicality.
How scoring works
$99.00($6.60 per serving)
Pure Formulas
$ 99.00
iHerb
$ 0.00
Report prices

Analysis

Cognitive and mental-energy support are the clear strengths. Acetyl-L-carnitine at 500 mg, bacopa and rhodiola at 300 mg each, L-theanine at 200 mg, citicoline at 150 mg, phosphatidylserine at 100 mg, and active B-vitamin forms cover memory, stress resilience, calm attention, and cellular energy.

Several supporting ingredients are less convincing than the headline stack. Alpha-GPC is modest at 200 mg, ginkgo is only 50 mg with incomplete marker detail, taurine is low at 200 mg, and algae-derived DHA reaches just 80 mg, so these components should not be treated as full standalone doses.

Seven capsules combine coffee fruit, theobromine, phenylalanine, N-acetyl-L-tyrosine, mucuna-derived L-Dopa, huperzine, choline donors, and calming ingredients in one serving. That complexity may suit experienced users seeking strong daytime focus, but it makes individual effects hard to predict and is a poor match for sleep support or medication-sensitive users.

Who is it for
  • Experienced supplement users seeking broad daytime cognitive support
  • Adults whose focus and mental energy decline under stress
  • People willing to use a seven-capsule serving and assess tolerance carefully
Best for
  • Daytime mental focus and productivity
  • Stress-related cognitive fatigue
  • Broad multi-pathway nootropic support

Pros

  • Strong 500 mg acetyl-L-carnitine amount
  • Bacopa, rhodiola, and L-theanine are present at meaningful doses
  • Combines citicoline, Alpha-GPC, and phosphatidylserine for cholinergic and membrane support
  • Uses active forms of vitamin B6 and B12
  • Individual active weights are broadly disclosed
  • Algae provides a non-fish DHA source

Cons

  • Requires seven capsules per serving
  • Only fifteen servings per bottle
  • Ginkgo, taurine, Alpha-GPC, and DHA are modest for focused use
  • Several botanical marker percentages are missing
  • Very crowded formula makes individual effects hard to identify
  • Poor fit for sleep, vision, weight loss, or dedicated DHA support

Warnings

  • Ginkgo may increase bleeding risk when combined with anticoagulant or antiplatelet medicines.
  • Mucuna-derived L-Dopa can interact with dopaminergic medicines, MAO inhibitors, and some psychiatric medicines; users of those treatments should have the combination reviewed before use.
  • Huperzine A and the two choline donors may intensify cholinergic effects or conflict with anticholinergic medicines.
  • Coffee fruit, theobromine, tyrosine-related precursors, rhodiola, and L-Dopa may cause jitteriness, anxiety, a fast heartbeat, or sleep disruption in sensitive users.
  • Twenty milligrams of vitamin B6 is a meaningful long-term supplemental amount; stop use and seek guidance if tingling, numbness, or other nerve symptoms develop.
  • The activating profile makes late-day use a poor choice for people prone to insomnia.

Nutrient quality

57 Moderate impact

Active B vitamins, citicoline, acetyl-L-carnitine, theanine, bacopa, and rhodiola provide substantial nootropic depth. Underdosed DHA, ginkgo, taurine, and Alpha-GPC combine with an implausibly high Huperzine A listing and a crowded mix of competing effects.

Ingredient transparency

73 High impact

Individual ingredient weights are listed without a proprietary blend. Missing marker percentages, unclear active yields, absent excipient details, and incomplete use directions still limit interpretation.

Customer satisfaction

61 Moderate impact

The average rating is good, but the review count is limited for a complex premium formula. No review text is supplied to assess recurring complaints, tolerance, or alignment with the many stated purposes.

Value for money

37 Lower impact

Several premium and meaningfully dosed nootropics partly support the high cost. The very costly serving, heavy capsule burden, uneven dosing, and incomplete extract detail make the formula weak value for any single purpose.

Report analysis

Goals

Energy
Essential Energy Nutrients
Energy
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA+ CoverageB- Formula Quality
Vitamin D · 25 mcgVitamin B5 · 50 mgThiamin · 50 mgVitamin B12 · 1000 mcgAcetyl L-Carnitine · 500 mg

High-dose methylcobalamin, acetyl-L-carnitine, rhodiola, tyrosine, cholinergic compounds, coffee fruit, and theobromine cover metabolic energy, focus, alertness, and stress resilience. Several ingredients have useful human evidence and meaningful disclosed amounts.

Many actives use named standardized or branded forms, and key doses are transparent. The seven-capsule formula stacks numerous neurologically active ingredients, increasing interaction and overstimulation risk despite substantial dose depth. Coffee-derived stimulants, theobromine, mucuna-derived L-Dopa, and huperzine may produce excessive stimulation or drug interactions, particularly with dopaminergic or cholinergic medicines.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Rhodiola Supportive 18 studies
Theobromine Adverse 1 study
Mental Focus
Mental Focus
Impact
Highest effect
A+ Goal FitA- Strength of SupportA CoverageB Formula Quality
Vitamin B6 · 20 mgVitamin D · 25 mcgVitamin B12 · 1000 mcgAlpha-GPC · 200 mgAcetyl L-Carnitine · 500 mgTheanine · 200 mg

Acetyl-L-carnitine, bacopa, rhodiola, theanine, cholinergic compounds, tyrosine-related precursors, phosphatidylserine, theobromine, and coffee fruit create exceptionally broad cognitive coverage. Many headline ingredients are supplied at useful amounts and use recognized forms.

Several ingredients remain below preferred focused doses, including Alpha-GPC and ginkgo, while the seven-capsule formula is very dense and partly redundant. Ginkgo may increase bleeding risk when combined with anticoagulant or antiplatelet medicines.

Study evidence
Acetyl L-Carnitine Supportive 7 studies
Alpha-GPC Supportive 1 study
Ginkgo Supportive 28 studies
Rhodiola Supportive 15 studies
Theanine Supportive 19 studies
Mood Support
Mood Support
Impact
Highest effect
A- Goal FitA Strength of SupportA CoverageC+ Formula Quality
Vitamin B6 · 20 mgVitamin B12 · 1000 mcgVitamin D · 25 mcg

Rhodiola, L-theanine, active vitamin B6, methylcobalamin, bacopa, taurine, and phosphatidylserine provide strong mood-related coverage. Rhodiola at 300 mg, L-theanine at 200 mg, and several other actives reach meaningful supplemental amounts.

The formula spans stress adaptation, calm attention, neurotransmitter cofactors, and neuronal membrane support. Calming and adaptogenic actives are paired with active B-vitamin cofactors and structural brain nutrients.

Study evidence
Rhodiola Supportive 15 studies
Theanine Supportive 12 studies
Vitamin B6 Supportive 19 studies
Cognitive Support
Mental Energy
Cognitive Support
Impact
Highest effect
A Goal FitB Strength of SupportA CoverageC Formula Quality
Thiamin · 50 mgVitamin B6 · 20 mgVitamin B12 · 1000 mcgVitamin D · 25 mcgAcetyl L-Carnitine · 500 mgAlpha-GPC · 200 mgTheanine · 200 mg

Bacopa, rhodiola, acetyl-L-carnitine, citicoline, theanine, phosphatidylserine, and several precursors create unusually broad cognitive coverage. Strong amounts support memory, stress resilience, brain energy, and neurotransmitter pathways, while ginkgo and Alpha-GPC are comparatively light.

The stack discloses individual weights but omits several botanical marker percentages and active-yield details. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines, and the crowded formula makes interaction review important.

Study evidence
Acetyl L-Carnitine Supportive 20 studies
Alpha-GPC Supportive 15 studies
Ginkgo Supportive 87 studies
Rhodiola Supportive 7 studies
Theanine Supportive 25 studies
Brain Health
Essential Brain Nutrition
Brain Health
Impact
Highest effect
A Goal FitB Strength of SupportB+ CoverageC Formula Quality
Vitamin B12 · 1000 mcgVitamin B6 · 20 mgVitamin D · 25 mcgThiamin · 50 mgAlpha-GPC · 200 mg

A broad set of nootropics targets memory, focus, stress resilience, neurotransmitter production, and cellular energy. Bacopa, rhodiola, phosphatidylserine, choline donors, acetyl-L-carnitine, and theanine create unusually strong goal alignment.

Many important actives are supplied at useful amounts, but several extracts omit marker percentages and some ingredients appear modest. The formula is thoughtfully layered yet extremely crowded, making interactions and the contribution of each component harder to judge.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Rhodiola Supportive 8 studies
Theanine Supportive 17 studies
Productivity Boost
Cognitive Energy and Stamina
Productivity Boost
Impact
High effect
A- Goal FitB+ Strength of SupportB+ CoverageC Formula Quality
Vitamin B12 · 1000 mcgVitamin B12 · 1000 mcgVitamin B6 · 20 mgAcetyl L-Carnitine · 500 mgAcetyl L-Carnitine · 500 mgAlpha-GPC · 200 mgTheanine · 200 mg

A broad nootropic stack directly targets memory, attention, mental energy, and stress resilience. Bacopa, rhodiola, theanine, citicoline, alpha-GPC, acetyl-L-carnitine, and phosphatidylserine provide multiple evidence-based components.

Many doses are meaningful, though some actives are modest and the very large stack makes individual effects difficult to predict. Mucuna-derived L-Dopa and huperzine A can interact with dopaminergic or cholinergic medicines and may increase adverse effects.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Acetyl L-Carnitine Supportive 1 study
Alpha-GPC Supportive 2 studies
Rhodiola Supportive 7 studies
Theanine Supportive 5 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 100 mg
Vitamin D3 (Cholecalciferol)
 25 mcg
Thiamine (Thiamine Hydrochloride)
 50 mg
Niacin (Niacinamide)
 50 mg
Vitamin B6 (Pyridoxal 5-Phosphate)
 20 mg
Vitamin B12 (Methylcobalamin)
 1000 mcg
Pantothenic Acid (Calcium Pantothenate)
 50 mg
Acetyl-L-Carnitine HCl
500 mg
Artichoke leaf extract (Cynarin, Flavonoids)
 500 mg
Bacopa monnieri leaf extract (Bacosides)
 300 mg
Rhodiola rosea root extract (Rosavins, Salidroside)
 300 mg
DL-Phenylalanine
300 mg
Uridine-5'-Monophosphate Heptahydrate Disodium
250 mg
N-Acetyl-L-Tyrosine
250 mg
Taurine
200 mg
L-Theanine
200 mg
Alpha-Glycerylphosphorylcholine
200 mg
Cognizin Citicoline
150 mg
organic Coffeeberry whole Coffee (Coffea arabica) fruit extract
129 mg
Velvet Bean (Mucuna pruriens) seed extract (L-Dopa)
 100 mg
Phosphatidylserine (Sunflower Lecithin)
 100 mg
Theobromine
100 mg
Docosahexaenoic Acid (Algae)
 80 mg
Celastrus paniculatus seed extract
60 mg
Ginkgo biloba leaf extract (Glycosides)
 50 mg
Coleus forskohlii root extract (Forskolin)
 20 mg
Pyrroloquinoline Quinone Disodium
10 mg
Huperzia serrata leaf extract (Huperzine A)
 5 mg
Adults 18–50 Women
Report overview
Theobromine · 100 mg OverallScore86
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Standalone theobromine reaches a well-aligned amount and is fully disclosed within a broad cognitive-support formula. Numerous substantial supporting ingredients add value, but no theobromine purity percentage is provided. The very high serving cost makes it poor value for theobromine alone, even though the formula is not primarily a theobromine supplement.

View ingredientView products
Theanine · 200 mg OverallScore82
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Explicit L-theanine identity confirms the active isomer, but no branded source or purity testing is shown. The clearly disclosed amount falls within the optimal range for calm and focused support. Several clinically dosed premium nootropic ingredients partly offset the very high serving cost.

View ingredientView products
Acetyl L-Carnitine · 500 mg OverallScore79
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The formula supplies ALCAR HCl at an effective standard-range amount. Its exact dose is clearly disclosed, though no manufacturing or purity assurance is provided. Cost per effective ALCAR amount is excessive, but several premium, well-dosed cognitive ingredients partly justify the broader formula price.

View ingredientView products

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsAnti-Aging forAcetyl L-Carnitine
  2. Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women.
    Chupel MU; Minuzzi LG; Furtado GE; Santos ML; Ferreira JP; Filaire E; Teixeira AM · Amino acids · 2021
    Randomized trial48 participantsAnti-Aging forTaurine
  3. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70.
    Abud GF; De Carvalho FG; Batitucci G; Travieso SG; Bueno Junior CR; Barbosa Junior F; Marchini JS; de Freitas EC · Nutrition (Burbank, Los Angeles County, Calif.) · 2022
    Randomized trial24 participantsAnti-Aging forTaurine
  4. Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study.
    Domoto T; Kise K; Oyama Y; Furuya K; Kato Y; Nishita Y; Kozakai R; Otsuka R · Frontiers in nutrition · 2024
    Cohort studyAnti-Aging forTaurine
  5. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  6. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  7. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  8. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  9. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  10. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  11. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  12. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  13. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health Productivity Boost forRhodiola
  14. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  15. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support forTheanine
  16. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  17. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  18. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  19. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  20. A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
    Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
    Randomized trial63 participantsCognitive Support forAcetyl L-Carnitine
  21. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
    Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
    Randomized trial96 participantsCognitive Support forAcetyl L-Carnitine
  22. Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
    Lee W; Kim M · Medicine · 2024
    Randomized trial119 participantsCognitive Support forAlpha-GPC
  23. Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
    Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
    Meta-analysis8 studies pooledCognitive Support forAlpha-GPC
  24. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forAlpha-GPC
  25. [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
    Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
    Meta-analysis10 studies pooledCognitive Support forAlpha-GPC
  26. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
    Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
    Cohort study7,659 participantsCognitive Support forAlpha-GPC
  27. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledCognitive Support forGinkgo
  28. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  29. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support forGinkgo
  30. Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
    Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
    Randomized trial410 participantsCognitive Support forGinkgo
  31. Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
    Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
    Randomized trial410 participantsCognitive Support forGinkgo
  32. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  33. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  34. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support Stress Relief forRhodiola
  35. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  36. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  37. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  38. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsEnergy forAcetyl L-Carnitine
  39. The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
    Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  40. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
    Randomized trial67 participantsEnergy forAcetyl L-Carnitine
  41. A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
    Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
    Randomized trial239 participantsEnergy forAcetyl L-Carnitine
  42. Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
    Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
    Systematic reviewEnergy forAcetyl L-Carnitine
  43. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  44. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  45. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  46. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy Stress Relief forRhodiola
  47. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  48. Sleep symptoms associated with intake of specific dietary nutrients.
    Grandner MA; Jackson N; Gerstner JR; Knutson KL · Journal of sleep research · 2014
    Cross-sectional study4,552 participantsEnergy forTheobromine
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    Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
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    Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
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    Kerksick CM · Nutrients · 2024
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    Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
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    Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
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    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
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    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
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