St. John's Wort Extended Release
NaturesPlus Herbal Actives
St. John's Wort Extended Release
4.6
★ ★ ★ ★ ★
(394 ratings)
St. John's Wort 450 mg
Score 88.0
A high-dose, extended-release standardized St. John's Wort extract for sustained effects, offering premium quality at a high cost.
Quantity: 60 Tablet(s)Servings size: 1 Extended Release Tablet(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 88.0
A high-dose, extended-release standardized St. John's Wort extract for sustained effects, offering premium quality at a high cost.
insights Analysis
NaturesPlus Herbal Actives St. John's Wort features a 450mg extract, standardized to Hypericin, in an extended-release tablet form. The higher dosage, combined with the extended-release mechanism, is designed to provide sustained therapeutic levels of active compounds throughout the day, potentially leading to more consistent mood support and stress relief. This formulation is a significant advantage for those seeking prolonged benefits and convenience. However, these premium features contribute to a very high price per serving, making it one of the most expensive options available for St. John's Wort.
- Extended-release formulation ensures sustained delivery of active compounds, potentially offering more consistent daily effects.
- Higher 450mg dosage of standardized extract, which can be beneficial for more robust support.
- Convenient once-daily dosing due to extended-release mechanism.
- Very high price per serving, making it less economical for long-term use compared to non-ER alternatives.
- Fewer reviews compared to some popular brands, which may indicate a smaller user base.
- St. John's Wort can interact significantly with numerous medications, including antidepressants (SSRIs, MAOIs), oral contraceptives, blood thinners, and immunosuppressants, potentially leading to serious side effects like serotonin syndrome.
- It can cause increased sensitivity to sunlight (photosensitivity), making skin more prone to sunburn or rash, especially in fair-skinned individuals.
$23.76($0.39 per serving)
 iHerb | $ 23.76 | |
 Vitacost | $ 23.76 | |
 Walmart | $ 23.76 | |
 Amazon | $ 23.76 |
bolt Effectiveness for goals
Some research suggests St. John's Wort may be effective for mild to moderate depression. Its use for severe depression is not well-supported by evidence. Consultation with a healthcare professional is advisable before considering use.
For mild to moderate depression, some studies suggest St. John's Wort can be similarly effective to certain conventional antidepressants. However, it may have a different side effect profile and significant drug interactions. This comparison does not extend to all types or severities of depression.
Scientific research indicates that St. John's Wort extracts can be effective for treating mild to moderate depression, often showing comparable efficacy to some standard antidepressants. However, results can vary depending on the extract used and the specific study design. Research on its effectiveness for other conditions is less conclusive.
For mild to moderate depression, some studies suggest St. John's Wort may be as effective as certain prescription antidepressants. However, results can vary, and it is not generally recommended as a substitute for standard care for severe depression.
Clinical studies indicate that St. John's Wort can be effective for relieving symptoms of mild depression. Its efficacy in this context has been compared to that of some conventional antidepressants. However, individual responses may vary.
schedule Dosage, timing & forms
Common dosages of St. John's Wort extract often range from 300 mg to 900 mg per day. These dosages typically provide standardized amounts of active compounds like hypericin or hyperforin. It's important to check the product label for specific recommendations.
The effects of St. John's Wort are generally not immediate and may take several weeks to become noticeable. Individuals typically report feeling benefits after two to four weeks of consistent daily use. It's important to continue taking it as directed for the recommended duration.
The effects of St. John's Wort are typically not immediate and may take several weeks to become noticeable. Individuals often report initial changes within 2 to 4 weeks, with more pronounced benefits potentially appearing after 4 to 6 weeks of consistent use. This gradual onset is common for many herbal supplements.
Common dosages for St. John's Wort extracts, often standardized to hypericin or hyperforin, typically range from 300 mg to 900 mg per day. These doses are usually divided into two or three administrations throughout the day. The specific dosage can vary based on the extract's standardization and the product's concentration.
St. John's Wort is typically taken two to three times per day. Dividing the daily dose helps maintain consistent levels of its active compounds in the body. Always follow the specific instructions provided on the supplement's label or by a qualified healthcare professional.
health_and_safety Safety & interactions
No, St. John's Wort should not be taken with antidepressant medications, especially selective serotonin reuptake inhibitors (SSRIs). Combining them can lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high fever. Always consult a healthcare professional before combining St. John's Wort with any prescription drugs.
Yes, St. John's Wort can interact significantly with many antidepressant medications. This interaction may lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high blood pressure. It is crucial to consult a healthcare professional before combining St. John's Wort with any antidepressant.
St. John's Wort can interact significantly with many medications, reducing their effectiveness or increasing side effects. Common side effects may include photosensitivity, upset stomach, fatigue, and restlessness. It is important to discuss its use with a healthcare provider.
Yes, St. John's Wort significantly interacts with medications used for HIV/AIDS (e.g., protease inhibitors, NNRTIs) and immunosuppressants used after organ transplantation (e.g., cyclosporine). It can dramatically reduce the levels and effectiveness of these critical drugs. Such combinations are generally contraindicated and should be strictly avoided.
Yes, St. John's Wort is known to reduce the effectiveness of hormonal contraceptives, including birth control pills. This interaction can potentially lead to unintended pregnancy. It is recommended to use an alternative or additional method of contraception while taking St. John's Wort.
Ingredients
| Ingredient | Amount per serving |
|---|---|
St. John's Wort | 450 mg |
Categories
St. John's Wort 88.0
A high-quality, innovative St. John's Wort product with an extended-release feature, positioning it as a premium option in the category for sustained benefits.
Goals
Mood Support 90.0
The combination of high-dose standardization and extended-release provides consistent and prolonged mood regulation benefits throughout the day.
Stress Relief 90.0
Sustained release of active compounds offers more continuous relief from daily stressors, enhancing its effectiveness for stress management.
Sleep Support 90.0
Consistent management of mood and stress throughout the day, facilitated by the extended-release, can significantly lead to better quality and more restorative sleep.
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