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Organic Stinging Nettle

Dr. Mercola
4.7
★ ★ ★ ★ ★
(70 ratings)
Stinging Nettle 500 mg
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Score78
A tablet best suited to leaf-oriented histamine and inflammatory support. The leaf identity is clear, which is the main limitation for matching the formula to a specific goal.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
Anti-Inflammatory Support
Testosterone Support

Score 78

A tablet best suited to leaf-oriented histamine and inflammatory support. The leaf identity is clear, which is the main limitation for matching the formula to a specific goal.
How scoring works
$19.99($0.33 per serving)
Vitacost
$ 24.99
iHerb
$ 0.00
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$ 19.99
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Analysis

The label provides 500 mg organic nettle leaf powder. The leaf identity is clear, while raw powder is less concentrated and less predictable than a characterized extract.

Leaf material is better aligned with histamine and inflammatory signaling than with testosterone support. Human evidence remains situational, and it should not be viewed as a comprehensive inflammation formula.

Stinging nettle may add to the effects of diuretic medicines and increase fluid or electrolyte changes. The good value should be weighed against the leaf identity is clear and the resulting uncertainty about goal-specific potency.

Who is it for
  • Leaf-oriented histamine and inflammatory support
  • People who prefer a tablet
  • Users who accept the stated value trade-off
Best for
  • Leaf-oriented histamine and inflammatory support
  • Leaf-oriented botanical use
  • Simple single-herb routines

Pros

  • 500 mg organic nettle leaf powder is disclosed
  • Plant part is clearly identified
  • Focused nettle-only design

Cons

  • The leaf identity is clear
  • Raw powder is less concentrated and less predictable than a characterized extract
  • Limited direct evidence for testosterone support

Warnings

  • Stinging nettle may add to the effects of diuretic medicines and could increase fluid or electrolyte changes.
  • Do not rely on nettle as a testosterone treatment; direct human evidence is limited.
  • Use should match the clearly identified plant part because root and leaf are not interchangeable for every goal.

Nutrient quality

78 High impact

A substantial, clearly identified leaf amount supports basic nettle use. Raw powder without active-marker data offers less predictable potency than a characterized extract.

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Ingredient transparency

81 Highest impact

The leaf identity and amount are clear without a hidden blend. Full directions, active-marker data, and inactive ingredients remain absent.

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Customer satisfaction

67 High impact

Customer sentiment is very strong. The rating base provides reasonable confidence in the average, while no narrative feedback was supplied.

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Value for money

84 Highest impact

Serving economics are reasonable. Formula quality supports fair practical value.

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Report analysis

Goals

Anti-Inflammatory Support
Impact
Moderate effect
D+ Goal FitC- Strength of SupportF CoverageA- Formula Quality

Organic nettle leaf offers plausible but limited anti-inflammatory support. Raw powder is less concentrated and less clinically defined than a standardized extract.

The substantial amount and single-ingredient design are clear strengths. Missing active markers, extraction details, and contaminant testing limit confidence in potency and consistency.

Study evidence
Stinging Nettle Supportive 5 studies
Testosterone Support
Impact
Moderate effect
F Goal FitD Strength of SupportF CoverageA+ Formula Quality

Stinging nettle has a proposed role in free-hormone and prostate pathways, but direct human evidence for raising testosterone is limited. The raw leaf powder does not provide a standardized extract or a clearly established active dose.

The single-ingredient formula is transparent and free from distracting additions. Its value is better suited to basic nettle use than evidence-led testosterone support.

Study evidence

Ingredients

IngredientAmount per serving
organic Stinging Nettle leaf powder
500 mg
Adults 18–50 Organic
Report overview
Stinging Nettle · 500 mg OverallScore66
D Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB+ Value

Clear leaf identification supports informed use, while the standalone positioning does not favor one specific goal. A substantial raw-powder amount offers useful depth without the potency advantages of a concentrated extract. The low serving cost makes it a good-value basic nettle option.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  2. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  3. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  4. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  5. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle