Product Image

B-50

NOW
4.7
★ ★ ★ ★ ★
(34420 ratings)
Niacin 50 mg
PABA 25 mg
Vitamin B6 50 mg
Riboflavin 50 mg
Thiamin 50 mg
Vitamin B5 50 mg
Choline 25 mg
Product Image
Score77
Complete and economical B-vitamin coverage is offset by conventional forms and a 50 mg vitamin B6 dose that is too aggressive for routine long-term use.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Energy
Metabolism Boost

Score 77

Complete and economical B-vitamin coverage is offset by conventional forms and a 50 mg vitamin B6 dose that is too aggressive for routine long-term use.
How scoring works
$8.00($0.08 per serving)
Pure Formulas
$ 11.30
Vitacost
$ 12.63
iHerb
$ 11.62
Daily Vita
$ 11.00
Daily Vita
$ 8.00
Report prices

Analysis

Thiamine, riboflavin, niacinamide, vitamin B6, folate, vitamin B12, biotin, and pantothenic acid create broad support for normal energy metabolism. Most core B vitamins are supplied at 50 mg or a similarly high multiple of daily needs, so the formula is better described as high potency than balanced maintenance nutrition.

Pyridoxine hydrochloride and cyanocobalamin are conventional forms that require conversion before use. Choline at 25 mg is only a small addition, and PABA and inositol provide limited practical depth beside the main B vitamins.

Folate at 667 mcg DFE is clearly stated and provides substantial coverage. The simple serving and complete disclosure support ease of use, but the dose pattern is more aggressive than most adults need every day.

Who is it for
  • Adults seeking a high-potency B-complex for limited or clinician-directed use
  • People who value a simple once-daily serving
  • Users who have checked total vitamin B6 and folic acid intake from other products
Best for
  • Broad B-vitamin coverage
  • Supporting normal energy metabolism when intake is inadequate
  • Users prioritizing low serving cost over premium coenzyme forms

Pros

  • Includes all core B vitamins with stated amounts
  • Uses non-flushing niacinamide
  • Provides substantial thiamine, riboflavin, and pantothenic acid
  • Simple daily serving is easy to follow

Cons

  • 50 mg pyridoxine is unnecessarily high for a daily maintenance formula
  • Uses conventional cyanocobalamin and pyridoxine hydrochloride
  • Choline is modest at 25 mg
  • PABA and inositol add little to the core energy rationale

Warnings

  • Prolonged use of 50 mg vitamin B6 may cause tingling, numbness, or other nerve symptoms; stop use and seek advice if these occur.
  • Niacinamide at this amount may cause nausea or stomach discomfort in sensitive users.
  • PABA can interfere with sulfonamide antibiotics, so concurrent use should be reviewed with the prescriber.

Nutrient quality

73 High impact

The broad B-vitamin pattern provides substantial, focused coverage. Basic forms and an aggressive B6 amount reduce form quality and long-term balance.

.

Ingredient transparency

71 High impact

Active amounts are broadly disclosed without a hidden blend. Repeated vitamin names, missing directions, and absent tablet excipients reduce full clarity.

.

Customer satisfaction

71 High impact

The aggregate satisfaction signal is strong and supported by extensive volume. Missing review details prevent assessment of recurring complaints or purpose fit.

.

Value for money

96 Highest impact

The large supply delivers broad dosing at excellent serving value. Basic forms and high B6 remain the only major disadvantages against gentler options.

.
Report analysis

Goals

Energy
Impact
High effect
B+ Goal FitB- Strength of SupportC CoverageA Formula Quality
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

A complete B-complex supports the nutrient-dependent steps that convert food into cellular energy. High amounts of thiamin, riboflavin, niacin, and pantothenic acid provide focused metabolic coverage.

Standard vitamin forms and a B12 amount below the targeted energy threshold limit the advantage over basic deficiency support. The concentrated vitamin B6 amount also makes long-term daily use less suitable without a clear need.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Metabolism Boost
Impact
High effect
C Goal FitB Strength of SupportC CoverageA- Formula Quality
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

The high-potency B-vitamin blend supplies several cofactors used to turn food into cellular energy. Its role is foundational, so it is more relevant to correcting inadequate intake than directly raising metabolic rate.

Amounts are substantial and fully disclosed, but most vitamins use standard precursor forms. The focused formula is coherent, although it does not cover thermogenesis, thyroid support, or glycemic control.

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Hydrochloride, Vitamin B1)
50 mg
Riboflavin (Vitamin B2)
50 mg
Niacin (Niacinamide, Vitamin B3)
50 mg
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (Calcium Pantothenate)
50 mg
Choline (Choline Bitartrate)
25 mg
PABA
25 mg
Inositol
25 mg
Gluten Free Adults 18–50 Vegan Kosher Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The B-complex uses clearly named niacinamide at a useful general-support amount. A standard capsule offers no special release control, but niacinamide itself has low flush potential. The serving cost is especially favorable for the included B-vitamin profile.

PABA · 25 mg OverallScore88
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The clearly listed 25 mg PABA amount fits a standard B-complex or high-potency combination dose. No purity grade is stated, but immediate release is appropriate and the exact amount is easy to verify. Cost efficiency is moderate, although the active amount does not reach the leading value tier.

C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

A 50 mg dose fits the preferred range for focused vitamin B6 support. Pyridoxine HCl is not the active coenzyme form, though the included riboflavin may support its conversion. A single capsule and a low serving cost keep the formula practical.

Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  2. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  3. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  4. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  5. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  6. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  7. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  8. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  9. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  10. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  11. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  12. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin