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B-Complex '50'

Solgar
4.8
★ ★ ★ ★ ★
(2497 ratings)
Niacin 50 mg
Vitamin B6 50 mg
Riboflavin 50 mg
Thiamin 50 mg
Vitamin B5 50 mg
Choline 21 mg
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Score74
Broad B-50 coverage comes in a convenient capsule, but the 50 mg B6 amount is not a sensible long-term maintenance dose. Active-form and choline quality are also limited.
How scoring works
Quantity:250 Capsule(s) • (250 servings)
Goals:
Energy
Metabolism Boost

Score 74

Broad B-50 coverage comes in a convenient capsule, but the 50 mg B6 amount is not a sensible long-term maintenance dose. Active-form and choline quality are also limited.
How scoring works
$25.87($0.10 per serving)
Walmart
$ 28.29
Vitacost
$ 27.39
Vitacost
$ 27.39
Daily Vita
$ 27.44
iHerb
$ 25.87
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Analysis

Most major B vitamins are supplied at high amounts, with folate, B12, D-biotin, pantothenic acid, choline, and inositol also included. The formula is broad enough for general B-complex use without unrelated ingredients.

Pyridoxine hydrochloride, cyanocobalamin, and unspecified folate are functional but less desirable than active forms. Choline bitartrate is present at only 21 mg and should not be treated as a meaningful choline serving.

A 50 mg vitamin B6 amount is unnecessarily aggressive for everyday maintenance. The one-capsule format is easy to use, but the large package encourages prolonged exposure to a dose better reserved for a defined need.

Who is it for
  • Adults seeking a high-potency B complex
  • People planning limited-duration use
  • Users comfortable with conventional vitamin forms
Best for
  • Short-term high-potency supplementation
  • One-capsule B-complex coverage
  • General metabolic nutrient support

Pros

  • Covers all core B vitamins
  • Includes D-biotin
  • Provides inositol and choline
  • Uses a simple one-capsule serving

Cons

  • Vitamin B6 is high for daily long-term use
  • Uses cyanocobalamin
  • Folate form is not disclosed
  • Choline is lightly dosed

Warnings

  • The 50 mg vitamin B6 amount may cause tingling, numbness, or other nerve symptoms with prolonged daily use.
  • Do not combine it with another high-B6 formula unless a clinician has set the total intake.

Nutrient quality

65 Moderate impact

The formula relies on pyridoxine hydrochloride, cyanocobalamin, and other conventional B-vitamin forms. The high vitamin B6 amount creates a meaningful neuropathy concern with long-term use.

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Ingredient transparency

79 High impact

Named vitamins have exact amounts, while the herbal blend components do not. A small herbal blend hides its ingredients, though it is not central to the formula.

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Customer satisfaction

71 High impact

The supplied aggregate rating is very strong. No complaint themes or purpose-specific experience details are supplied.

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Value for money

81 Highest impact

The formula offers reasonable value despite important quality or dose trade-offs. The tiny herbal blend and modest choline add little to the core formula.

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Goals

Energy
Impact
High effect
B+ Goal FitB- Strength of SupportC CoverageA- Formula Quality
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

A complete B-complex supports the nutrient-dependent steps that convert food into cellular energy. High amounts of thiamin, riboflavin, niacin, and pantothenic acid provide focused metabolic coverage.

Standard vitamin forms and a B12 amount below the targeted energy threshold limit the advantage over basic deficiency support. The concentrated vitamin B6 amount also makes long-term daily use less suitable without a clear need.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Metabolism Boost
Impact
High effect
C Goal FitB Strength of SupportC CoverageA- Formula Quality
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

The high-potency B-vitamin blend supplies several cofactors used to turn food into cellular energy. Its role is foundational, so it is more relevant to correcting inadequate intake than directly raising metabolic rate.

Amounts are substantial and fully disclosed, but most vitamins use standard precursor forms. The focused formula is coherent, although it does not cover thermogenesis, thyroid support, or glycemic control.

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Mononitrate, Vitamin B1)
50 mg
Riboflavin (Vitamin B2)
50 mg
Niacin (Niacinamide, Vitamin B3)
50 mg
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg
Folate
666 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin (D-Biotin)
50 mcg
Pantothenic Acid (D-Calcium Pantothenate, Vitamin B5)
50 mg
Choline (Choline Bitartrate)
21 mg
Inositol
50 mg
Herbal Powdered Blend
3.5 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

The B-complex uses clearly named niacinamide at a useful general-support amount. A standard capsule offers no special release control, but niacinamide itself has low flush potential. The large package delivers particularly favorable value per serving.

C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Pyridoxine hydrochloride is less metabolically ready than P-5-P, but riboflavin may help support conversion. The 50 mg serving is well aligned with the preferred dose range and needs only one capsule. Low serving cost offers strong value.

D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Standard riboflavin requires enzymatic conversion before it becomes metabolically active, while the capsule should dissolve readily. The amount reaches the high-potency range for metabolic support. The low serving cost makes the clearly stated dose highly efficient.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin B6 metabolism.
    Whyte MP; Zhang F; Mack KE; Wenkert D; Gottesman GS; Ericson KL; Cole JT; Coburn SP · Bone · 2024
    Non-randomized trial149 participantsMetabolism Boost forVitamin B6
  2. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  3. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  4. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  5. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  6. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  7. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  8. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  9. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  10. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  11. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  12. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  13. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin