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Vitamin D3 + K2 50 mcg (2000 IU) & 90 mcg

4.9
★ ★ ★ ★ ★
(2312 ratings)
Vitamin K 90 mcg
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Score84
A balanced, clearly labeled D3 and MK-7 combination offers useful daily support, with dry delivery and incomplete bone-nutrient breadth as trade-offs.
How scoring works
Capsule
Quantity:120 Capsule(s) • (60 servings)
Goals:
Bone Health
Heart Health
Cardiovascular Support

Score 84

A balanced, clearly labeled D3 and MK-7 combination offers useful daily support, with dry delivery and incomplete bone-nutrient breadth as trade-offs.
How scoring works
$27.63($0.46 per serving)
iHerb
$ 27.63
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Analysis

Vitamin D3 supports calcium absorption, while 90 mcg of MK-7 supports calcium placement through vitamin-K-dependent proteins. Both amounts are meaningful without being as aggressive as some high-dose combinations.

The two-active formula is coherent and easy to assess. Its dry capsules lack a built-in lipid carrier, and the supplied label does not identify a branded MK-7 source.

Adults seeking a balanced D3 and K2 formula are the clearest fit. It complements adequate calcium, magnesium, and protein intake rather than replacing those building blocks.

Who is it for
  • Adults seeking a balanced D3 and K2 combination
  • People focused on bone and vascular support
  • Users who obtain calcium and magnesium elsewhere
Best for
  • Daily calcium-handling support
  • Moderate-strength D3 plus MK-7
  • A compact two-active formula

Pros

  • Provides 90 mcg of MK-7
  • Includes 50 mcg of vitamin D3
  • Clearly discloses both active forms
  • Uses a coherent two-nutrient pairing

Cons

  • Dry-capsule delivery gives no built-in fat source for this fat-soluble nutrient
  • The supplied label does not identify a branded or verified all-trans MK-7 source
  • Does not provide calcium or magnesium
  • Requires two capsules per serving

Warnings

  • Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants; use requires prescriber-guided consistency.
  • Count the 50 mcg vitamin D3 serving alongside fortified foods and other supplements.
  • Fat-malabsorption conditions can make vitamin K uptake unreliable, so response may need clinical monitoring.

Nutrient quality

92 Highest impact

Well-regarded forms and meaningful doses create a focused combination. The formula is balanced and avoids unrelated active ingredients.

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Ingredient transparency

82 Highest impact

The active forms and amounts are clear with no proprietary blend. Missing intake directions and capsule excipients are the main disclosure gaps.

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Customer satisfaction

73 High impact

Aggregate satisfaction is very strong and supported by an extensive evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment cannot be checked.

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Value for money

86 Highest impact

Useful forms and a sound serving position support good value. The package remains competitive in its category.

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Goals

Bone Health
Bone Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin D3 and MK-7 form a well-matched pair for calcium absorption and its use in bone. Both nutrients have established roles in skeletal mineral handling.

The clearly stated amounts appear substantial, and MK-7 is a well-defined vitamin K2 form. The formula does not provide calcium, magnesium, or collagen, so users still depend on other sources for the structural materials.

Study evidence
Vitamin K Supportive 78 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitA Strength of SupportB- CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin K2 as MK-7 provides direct calcium-management support that is relevant to arterial health. Vitamin D3 complements that pathway by supporting calcium absorption and regulation.

The 90 mcg MK-7 amount is clearly disclosed, and the MK-7 form has a long duration of action. The pairing is compact and logically constructed. Vitamin K can counteract warfarin and other vitamin K antagonist medicines, so users of those drugs need clinician-guided intake. No other meaningful product-specific concern is evident from the supplied formula.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 90 mcgVitamin D · 50 mcg

Vitamin D3 and MK-7 form a strong calcium-handling combination with clear vascular relevance. Evidence supports nutrient status and calcification-related markers, while direct cardiovascular outcome evidence is still limited.

The 50 mcg D3 and 90 mcg MK-7 amounts are both meaningful. The pairing is highly coherent, but vitamin K2 can oppose warfarin and other vitamin K antagonist anticoagulants.

Study evidence
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
 50 mcg
Vitamin K2 (Menaquinone-7)
 90 mcg
Gluten Free Adults 18–50 Women
Report overview
Vitamin K (Menaquinone-7) · 90 mcg OverallScore83
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

A clinically aligned 90 mcg MK-7 dose is paired with Vitamin D3 for complementary bone support. The generic MK-7 source is clearly identified but lacks branded or all-trans verification. Dry capsules without meal guidance limit absorption optimization.

View ingredientView products
Loading alternative details
86 Performance

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
Compared with 50 mcg of vitamin D3 with 90 mcg of MK-7 vitamin K2, the alternative provides 90 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
86 Performance

Vitamins D3 1000 IU (25 mcg) & K2 100 mcg

NaturesPlus
Compared with 50 mcg of vitamin D3 with 90 mcg of MK-7 vitamin K2, the alternative provides 25 mcg of vitamin D3 with 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its dry capsule lacks a lipid carrier, and MK-7 requires consistent intake for people using warfarin.
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
Compared with 50 mcg of vitamin D3 with 90 mcg of MK-7 vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants.
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
The supplied serving cost is lower, while the formula provides 100 mcg of MK-7 vitamin K2. Vitamin K2 can interfere with warfarin-type anticoagulants.
89 Budget

Mega D-3 5000 IU & MK-7 180 mcg

NOW
The supplied serving cost is lower, while the formula provides 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2. High vitamin D remains the main dosing limitation, while the dry capsule lacks stated fat-intake guidance.
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
The supplied serving cost is lower, while the formula provides vitamin k2. Its vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake.
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
62.5 mcg of vitamin D3 with 120 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its dry tablet lacks a lipid carrier, and MK-7 requires consistent intake for people using warfarin.
88 Value

D3 + K2 Green Apple

EZ Melts
125 mcg of vitamin D3 with 120 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. High vitamin D and absent fat-based delivery guidance are the main limitations, while value is favorable.
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
125 mcg of vitamin D3 with 100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Vitamin K2 can interfere with warfarin-type anticoagulants.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  3. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  4. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  5. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  6. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  7. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support forVitamin D
  8. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  9. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  10. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  11. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support forVitamin D
  12. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  13. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  14. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  15. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  16. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  17. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K