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Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
4.8
★ ★ ★ ★ ★
(5590 ratings)
Vitamin K 100 mcg
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Score86
Best suited to adults with a defined high-vitamin-D need who also want MK-7; vitamin D reaches the usual adult daily upper limit, so the strong value does not make it an appropriate routine dose for everyone.
How scoring works
Quantity:120 Softgel(s) • (120 servings)
Goals:
General Health
Anti-Aging
Heart Health
Bone Health
Cardiovascular Support

Score 86

Best suited to adults with a defined high-vitamin-D need who also want MK-7; vitamin D reaches the usual adult daily upper limit, so the strong value does not make it an appropriate routine dose for everyone.
How scoring works
$14.95($0.12 per serving)
iHerb
$ 14.95
Walmart
$ 14.95
Vitacost
$ 14.95
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Analysis

A softgel combines 100 mcg MK-7 with 125 mcg vitamin D3 in a coherent, exceptionally economical formula. The label provides enough detail to judge the central vitamin strategy.

Vitamin D reaches the usual adult daily upper limit, so the strong value does not make it an appropriate routine dose for everyone. Format, dose, and companion nutrients determine whether it is appropriate for daily use.

The best fit is adults with a defined high-vitamin-D need who also want MK-7. Vitamin K and vitamin D support normal physiology, but the practical benefit depends on baseline intake and individual need.

Who is it for
  • Adults with a defined high-vitamin-D need who also want MK-7
  • Adults whose current vitamin intake matches the listed potency
  • Users able to account for vitamin K medication interactions
Best for
  • Long-acting MK-7 form
  • Softgel supports fat-soluble delivery
  • Users who accept that vitamin d amount is high

Pros

  • Long-acting MK-7 form
  • Softgel supports fat-soluble delivery
  • Large 120-serving supply
  • Very strong serving value

Cons

  • Vitamin D amount is high
  • Not suited to casual supplement stacking
  • MK-7 source and carrier are not supplied
  • No lower-dose D3 option within the serving

Warnings

  • The 125 mcg vitamin D3 serving reaches the usual adult daily upper limit and should not be stacked casually with other vitamin D products.
  • The 100 mcg MK-7 serving can counteract warfarin and related vitamin K antagonist anticoagulants.
  • High vitamin D intake may worsen hypercalcemia or some kidney-stone risks, particularly when calcium intake is also high.

Nutrient quality

86 Highest impact

Cholecalciferol and MK-7 are useful forms delivered in a suitable softgel, and the 100 mcg MK-7 amount is meaningful, while the 125 mcg vitamin D3 amount is concentrated. The vitamin D3 amount reaches a concentrated daily level that may be excessive when status is already adequate, while vitamin D3 and K2 form a coherent combination for calcium handling and bone support.

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Ingredient transparency

85 Highest impact

Every listed active ingredient has a specific amount, and no proprietary blend hides the dose of a listed active ingredient. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

75 High impact

The supplied average rating is strong, and extensive review volume makes the average rating more dependable. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

96 Highest impact

The ingredient forms and dosing generally justify the product positioning, and the very low serving cost provides excellent practical value. The focused active profile is not inflated by low-value additions, while the formula and serving value compare well with similar products.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitB+ Strength of SupportB+ CoverageA+ Formula Quality
Vitamin D · 125 mcgVitamin K · 100 mcg

MK-7 and vitamin D3 directly support calcium handling and foundational bone health. Both active amounts are stated clearly, and the softgel is a practical format for fat-soluble nutrients.

The vitamin D amount is high for routine unsupervised use and can raise calcium exposure in susceptible users. Vitamin K can interfere with warfarin and other vitamin K antagonist medicines, so dosing must remain clinician-guided and consistent for those users.

Study evidence
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 125 mcg

MK-7 and vitamin D3 form a strong bone-and-calcium partnership that supports function with age. Its healthy-aging value is mainly foundational for skeletal and vascular function rather than a direct cellular-longevity effect.

Both amounts are clearly disclosed, though the D3 dose is at the high end for daily maintenance. Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants, so medicine dosing requires clinician-guided consistency.

Study evidence
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 125 mcg

Menaquinone-7 and vitamin D3 form a complementary calcium-management pair relevant to vascular and bone health. The MK-7 amount is useful and clearly disclosed in a fat-compatible softgel.

Vitamin D3 is supplied at 125 mcg, which is above the usual adult upper intake level for unsupervised daily use. Vitamin K can oppose warfarin and related vitamin K antagonist medicines, so users of those drugs need clinician-guided consistency.

Study evidence
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Bone Health
Bone Health
Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 125 mcg

Menaquinone-7 and vitamin D3 form a focused pair for calcium handling and bone signaling. The vitamin K2 amount fits common supplemental use and the named MK-7 form is long acting.

Vitamin D3 is supplied at a high daily amount that may be unsuitable without considering total intake and clinical need. No calcium, magnesium, or protein-matrix ingredient is present, so the formula supports regulation rather than supplying bone-building material.

Study evidence
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B- Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 100 mcgVitamin D · 125 mcg

MK-7 may support arterial calcium handling, with a stronger cardiovascular rationale than vitamin K1 or short-acting MK-4. Human evidence supports vascular calcification markers, though direct cardiovascular outcome evidence remains developing.

The MK-7 amount reaches a practical daily range. Menaquinone-7 and its amount are clear, but source and all-trans isomer quality are not identified.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
 125 mcg
Vitamin K (Menaquinone-7)
 100 mcg
Gluten Free Adults 18–50 Vegetarian
Report overview
Vitamin K (Menaquinone-7) · 100 mcg OverallScore90
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The MK-7 dose sits in the useful daily range and is paired with vitamin D3, which supports a bone-focused use case. The very low serving cost adds strong value, although the MK-7 source and isomer quality are not identified. Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants, so users of these medicines need clinician-guided consistency.

View ingredientView products
Loading alternative details
87 Performance

Vitamin K2 100 mcg

SR Sports Research
<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Performance

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
<p>The formula provides 90 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K (Menaquinone-7), making it a practical budget alternative to the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Budget

MK-7 Vitamin K-2 100 mcg

NOW
<p>Although it is not strictly cheaper per serving, this is among the lowest-cost eligible options and provides 100 mcg of Vitamin K2 (Menaquinone-7) as an alternative to 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
<p>Although it is not strictly cheaper per serving, this is among the lowest-cost eligible options and provides 100 mcg of Vitamin K2 (Natto) as an alternative to 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>The formula combines 120 mcg of Vitamin K2 (Menaquinone-7) and 62.50 mcg of Vitamin D3 (Cholecalciferol) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
<p>The formula combines 100 mcg of Vitamin K-2 (Menaquinone-7) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Value

Low Dose Vitamin K2 (MK-7) 45 mcg

Life Extension
<p>The formula combines 45 mcg of Vitamin K2 (Menaquinone-7) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  2. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  3. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  4. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  5. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  6. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  7. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  8. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  9. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  10. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  11. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  12. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  13. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  14. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  15. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  16. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  17. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  20. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  21. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  22. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  23. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  24. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  25. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  26. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  27. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  28. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  29. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  30. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  31. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  32. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  33. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  34. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  35. Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
    Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
    Randomized trial1,537 participantsHeart Health forVitamin D
  36. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsHeart Health forVitamin D
  37. Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
    Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
    Meta-analysis81 studies pooledHeart Health forVitamin D
  38. Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
    Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
    Meta-analysis45 studies pooledHeart Health forVitamin D
  39. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forVitamin D
  40. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K