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Vitamin K2 MK-7 100 mcg

Nutricost
4.8
★ ★ ★ ★ ★
(15616 ratings)
Vitamin K 100 mcg
Product Image
Score88
Best suited to value-focused users who want a large supply of standalone MK-7; dry delivery and an unnamed MK-7 source are the main compromises.
How scoring works
Quantity:240 Capsule(s) • (240 servings)
Goals:
General Health
Heart Health
Bone Health
Anti-Aging
Cardiovascular Support

Score 88

Best suited to value-focused users who want a large supply of standalone MK-7; dry delivery and an unnamed MK-7 source are the main compromises.
How scoring works
$16.16($0.06 per serving)
Vitacost
$ 17.95
iHerb
$ 17.95
Walmart
$ 16.16
iHerb
$ 17.95
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Analysis

A clearly disclosed 100 mcg MK-7 capsule provides focused long-acting vitamin K2 support with exceptional long-term value. The label provides enough detail to judge the central vitamin strategy.

Dry delivery and an unnamed MK-7 source are the main compromises. Format, dose, and companion nutrients determine whether it is appropriate for daily use.

The best fit is value-focused users who want a large supply of standalone MK-7. Vitamin K and vitamin D support normal physiology, but the practical benefit depends on baseline intake and individual need.

Who is it for
  • Value-focused users who want a large supply of standalone MK-7
  • Adults whose current vitamin intake matches the listed potency
  • Users able to account for vitamin K medication interactions
Best for
  • Long-acting MK-7 form
  • Useful daily amount
  • Users who accept that dry capsule lacks a fat carrier

Pros

  • Long-acting MK-7 form
  • Useful daily amount
  • Large 240-serving supply
  • Excellent serving value

Cons

  • Dry capsule lacks a fat carrier
  • MK-7 source is not identified
  • No companion vitamin D
  • Inactive ingredients are not supplied

Warnings

  • The 100 mcg vitamin K serving can counteract warfarin and related vitamin K antagonist anticoagulants.
  • Bile-acid sequestrants and orlistat can reduce absorption of fat-soluble vitamin K, which may make this capsule less reliable.
  • People with fat-malabsorption conditions may not absorb the listed vitamin K consistently and should use an individualized plan.

Nutrient quality

94 Highest impact

MK-7 is a well-regarded long-acting form, though the dry capsule has no stated lipid carrier, and the 100 mcg MK-7 amount is meaningful for daily vitamin K2 support. The vitamin K2 amount is not obviously excessive for general supplementation, while the single active is tightly focused on vitamin K2 support without mismatched additions.

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Ingredient transparency

84 Highest impact

Every listed active ingredient has a specific amount, and no proprietary blend hides the dose of a listed active ingredient. Serving count is supplied, but complete daily-use directions are not provided, while inactive ingredients and excipients are not included in the supplied label details.

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Customer satisfaction

76 High impact

The supplied average rating is strong, and extensive review volume makes the average rating more dependable. Specific review themes are unavailable, so repeated negatives and real-world fit remain uncertain.

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Value for money

97 Highest impact

The ingredient forms and dosing generally justify the product positioning, and the very low serving cost provides excellent practical value. The focused active profile is not inflated by low-value additions, while the formula and serving value compare well with similar products.

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Goals

General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 provides a long-acting vitamin K2 form at a useful daily amount. Exact form and dose disclosure support confident use for calcium metabolism.

The source lacks an all-trans purity guarantee, and conflicting capsule and softgel details leave lipid-based delivery uncertain. Vitamin K can interfere with warfarin and other vitamin K antagonist medicines, so users of those drugs need clinician-guided consistency.

Study evidence
Vitamin K Supportive 34 studies
Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 100 mcg

Menaquinone-7 provides a preferred long-acting vitamin K2 form for calcium regulation and vascular support. The 100 mcg amount is useful for a focused daily formula.

The label does not identify an all-trans purity standard or traceable MK-7 source, and the capsule description conflicts with the stated softgel serving. Vitamin K can oppose warfarin and related vitamin K antagonist medicines, so users of those drugs need clinician-guided consistency.

Study evidence
Vitamin K Mixed 62 studies
Bone Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC- CoverageB+ Formula Quality
Vitamin K · 100 mcg

Menaquinone-7 directly supports activation of calcium-binding proteins used in bone tissue. The supplied amount is well aligned with common MK-7 supplementation and the long-acting form is clearly disclosed.

No vitamin D, calcium, magnesium, or protein-matrix ingredient accompanies it. The product therefore offers meaningful depth in one signaling pathway but little broader skeletal coverage.

Study evidence
Vitamin K Supportive 78 studies
Anti-Aging
Impact
High effect
B+ Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 supports vitamin K-dependent calcium handling and long-term skeletal maintenance. Its healthy-aging value is mainly foundational for skeletal and vascular function rather than a direct cellular-longevity effect.

The 100 mcg amount is useful, but generic sourcing and conflicting delivery details leave absorption quality uncertain. Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants, so medicine dosing requires clinician-guided consistency.

Study evidence
Vitamin K Supportive 27 studies
Cardiovascular Support
Impact
High effect
C+ Goal FitA- Strength of SupportD CoverageA- Formula Quality
Vitamin K · 100 mcg

MK-7 may support arterial calcium handling, with a stronger cardiovascular rationale than vitamin K1 or short-acting MK-4. Human evidence supports vascular calcification markers, though direct cardiovascular outcome evidence remains developing.

The MK-7 amount reaches a practical daily range. Menaquinone-7 and its amount are clear, but source and all-trans isomer quality are not identified.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin K (Menaquinone-7)
100 mcg
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The disclosed MK-7 dose fits the useful daily range and the very low serving cost makes it economical. Generic sourcing leaves purity and all-trans isomer quality uncertain, while conflicting capsule and softgel details weaken confidence in lipid-based delivery. Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants, so users of these medicines need clinician-guided consistency.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  2. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  3. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  4. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  5. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  6. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  7. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  8. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  9. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  10. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  11. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  12. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  13. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  14. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  15. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  16. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  17. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  18. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  19. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  20. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K