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Magnesium Glycinate

NOW
4.8
★ ★ ★ ★ ★
(41745 ratings)
Magnesium 200 mg
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Score84
Glycinate is well absorbed and often gentler on digestion than oxide or larger citrate servings. No patented chelation standard is named, and two tablets are required for the full amount.
How scoring works
Quantity:180 Tablet(s) • (90 servings)
Goals:
Heart Health
General Health
Energy
Stress Relief
Cardiovascular Support
Digestive Health
Testosterone Support
Bone Health

Score 84

Glycinate is well absorbed and often gentler on digestion than oxide or larger citrate servings. No patented chelation standard is named, and two tablets are required for the full amount.
How scoring works
$18.50($0.20 per serving)
Vitacost
$ 20.95
iHerb
$ 19.59
Walmart
$ 19.99
Pure Formulas
$ 19.04
Daily Vita
$ 18.50
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Analysis

Two tablets provide 200 mg of elemental magnesium in the named glycinate form. Glycinate is well absorbed and often gentler on digestion than oxide or larger citrate servings.

The moderate amount suits routine stress, muscle, and general magnesium support while leaving room for dietary intake. A focused formula, large bottle, and low serving cost give it strong everyday value.

No patented chelation standard is named, and two tablets are required for the full amount. Choosing a dose that matches personal intake and tolerance is more useful than relying on the headline amount alone.

Who is it for
  • Adults seeking a well-absorbed magnesium form
  • People sensitive to oxide or large citrate servings
  • Users who want a moderate daily amount
Best for
  • Routine daily magnesium
  • Stress and muscle-support routines
  • Users who value digestive tolerance

Pros

  • Uses well-absorbed magnesium glycinate
  • Moderate 200 mg elemental amount
  • Likely gentler than high-dose oxide products
  • Large bottle and low serving cost

Cons

  • No patented chelation standard is identified
  • Two tablets are required per serving
  • Lower dose may not suit users seeking a large supplemental amount

Warnings

  • Magnesium glycinate can still cause stomach discomfort or loose stools in sensitive users, especially alongside other magnesium products.
  • Supplemental magnesium can accumulate with significant kidney impairment; use only with medical guidance in that situation.
  • Magnesium can reduce absorption of levothyroxine and tetracycline or quinolone antibiotics, so separate the doses as directed by a pharmacist.

Nutrient quality

94 Highest impact

Magnesium glycinate is a well-absorbed form that is often gentle on digestion. The 200 mg elemental amount is meaningful for supplemental use.

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Ingredient transparency

79 High impact

The elemental amount is clearly stated and no proprietary blend hides the dose. Missing other ingredients and complete intake directions leave important label details unresolved.

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Customer satisfaction

67 High impact

The supplied average rating is strong and the rating volume provides an aggregate signal. No comment-level evidence is provided to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

96 Highest impact

The form and usable amount support favorable serving value. The supplied active formula is not inflated by obvious low-value extras.

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Goals

Heart Health
Healthy Blood Pressure
Heart Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 200 mg

A useful magnesium amount directly supports normal heart rhythm, vascular tone, and energy metabolism. Glycinate offers strong absorption and digestive tolerance.

The focused formula is easy to assess and avoids competing minerals. It supports one important cardiovascular pathway rather than lipid management or antioxidant protection.

Study evidence
Magnesium Supportive 158 studies
General Health
Stress Resilience
General Health
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 200 mg

Magnesium is a foundational nutrient involved in energy metabolism, muscle function, and nervous-system regulation. The glycinate format supplies a useful daily amount in a focused formula.

The elemental amount is clear and the glycinate form generally supports good absorption and tolerance. Its narrow scope is appropriate for correcting or preventing a magnesium gap rather than acting as a comprehensive multivitamin.

Study evidence
Magnesium Supportive 114 studies
Energy
Energy
Impact
Highest effect
B Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Magnesium · 200 mg

Magnesium glycinate provides a well-absorbed mineral form at the stated energy threshold. Magnesium is essential for ATP-dependent reactions and may help when low intake contributes to fatigue.

The single-mineral design does not address alertness, mitochondrial cofactors, or stress resilience. It remains a strong focused option for magnesium support rather than a comprehensive energy product.

Study evidence
Magnesium Supportive 4 studies
Stress Relief
Stress Relief
Impact
Highest effect
B Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Magnesium · 200 mg

Magnesium supports nervous-system regulation and muscle relaxation, and the 200 mg amount is meaningful. Its stress-relief benefit is most likely when dietary intake or magnesium status is low.

Magnesium glycinate is a well-absorbed form, although no patented chelation standard is identified. The focused single-mineral formula does not cover adaptogen or neurotransmitter pathways.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageA+ Formula Quality
Magnesium · 200 mg

Magnesium glycinate provides direct support for vascular tone and normal cardiac rhythm. The clearly disclosed elemental amount reaches a useful daily range.

Glycinate offers favorable absorption and tolerability, strengthening practical contribution. The clean single-mineral design has strong depth but does not address lipids or endothelial antioxidant support.

Study evidence
Magnesium Supportive 123 studies
Digestive Health
Digestive Health
Impact
High effect
C+ Goal FitB+ Strength of SupportD- CoverageA+ Formula Quality
Magnesium · 200 mg

Magnesium glycinate supplies a well-absorbed, well-tolerated form at a meaningful daily amount. It may support normal motility, although glycinate is less directly suited to stool softening than citrate.

The focused formula is fully disclosed and avoids unnecessary ingredients. Its narrow action means it does not address fiber intake, food breakdown, microbiome support, or gut-barrier repair.

Study evidence
Magnesium Supportive 50 studies

Ingredients

IngredientAmount per serving
Magnesium
200 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Magnesium · 200 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

Magnesium glycinate provides a highly bioavailable form at a clearly stated elemental amount. The focused formula avoids competing minerals and suits routine supplementation, though no patented chelation standard is named. A low serving cost and premium form combine to provide strong value.

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Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  2. Hospital-Acquired Dysmagnesemia and In-Hospital Mortality.
    Cheungpasitporn W; Thongprayoon C; Chewcharat A; Petnak T; Mao MA; Davis PW; Bathini T; Vallabhajosyula S; Qureshi F; Erickson SB · Medical sciences (Basel, Switzerland) · 2024
    Cohort study26,020 participantsGeneral Health forMagnesium
  3. Magpie Trial in the UK: methods and additional data for women and children at 2 years following pregnancy complicated by pre-eclampsia.
    Smyth RM; Spark P; Armstrong N; Duley L · BMC pregnancy and childbirth · 2009
    Randomized trial1,601 participantsGeneral Health forMagnesium
  4. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledGeneral Health Cardiovascular Support forMagnesium
  5. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  6. Effects of zinc and magnesium supplements on postpartum depression and anxiety: A randomized controlled clinical trial.
    Fard FE; Mirghafourvand M; Mohammad-Alizadeh Charandabi S; Farshbaf-Khalili A; Javadzadeh Y; Asgharian H · Women & health · 2017
    Randomized trial99 participantsStress Relief forMagnesium
  7. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
    Rawji A; Peltier MR; Mourtzanakis K; Awan S; Rana J; Pothen NJ; Afzal S · Cureus · 2024
    Systematic review15 studies pooledStress Relief forMagnesium
  8. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  9. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  10. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  11. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  12. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  13. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  14. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  15. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  16. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  17. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  18. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  19. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  20. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  21. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  22. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  23. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  24. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  25. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  26. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  27. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  28. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  29. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  30. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  31. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  32. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  33. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  34. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  35. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  36. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  37. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  38. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  39. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  40. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  41. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  42. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  43. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  44. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  45. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium