Product Image

Life Extension Mix Tablets without Copper

Life Extension
4.7
★ ★ ★ ★ ★
(148 ratings)
Iodine 150 mcg
Ashwagandha 125 mg
Chromium 500 mcg
Selenium 200 mcg
Zinc 35 mg
Thiamin 125 mg
Biotin 3000 mcg
Product Image
Score70
Broad high-potency coverage is paired with a deliberately copper-free design. High zinc without copper and very high vitamin B6 make long-term self-directed use difficult to support.
How scoring works
Quantity:240 Tablet(s) • (30 servings)
Goals:
Heart Health
Detoxification
General Health
Anti-Inflammatory Support
Metabolism Boost
Stress Relief
Energy
Testosterone Support

Score 70

Broad high-potency coverage is paired with a deliberately copper-free design. High zinc without copper and very high vitamin B6 make long-term self-directed use difficult to support.
How scoring works
$55.45($1.84 per serving)
Pure Formulas
$ 55.50
iHerb
$ 55.50
Vitacost
$ 55.50
Amazon
$ 55.45
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Analysis

The formula retains the original tablet version's extensive vitamin, mineral, antioxidant, and botanical coverage. Active folate and B12, several mineral forms, decaffeinated green tea, and N-acetyl cysteine are notable strengths.

The copper-free design is useful only when copper avoidance is intentional. With 35 mg zinc and no copper, prolonged use could worsen copper balance, while vitamin B6 at 105 mg adds a separate nerve-symptom concern.

Eight tablets per serving and many aggressive amounts make this a demanding regimen. It best fits a user following a specific nutrition plan rather than someone choosing a general-purpose multivitamin.

Who is it for
  • Adults intentionally avoiding supplemental copper
  • Experienced users seeking a broad high-potency formula
  • People following a monitored nutrient plan
Best for
  • Copper-free high-potency coverage
  • Multiple antioxidant extracts
  • Users who value active B-vitamin forms

Pros

  • Copper-free option for a specific need
  • Uses methylfolate and methylcobalamin
  • Includes N-acetyl cysteine and EGCG-marked green tea
  • Provides several magnesium forms

Cons

  • Eight-tablet serving
  • 35 mg zinc is not balanced by copper
  • Vitamin B6 amount is unusually high
  • Many nutrients leave little room for stacking

Warnings

  • Vitamin B6 at 105 mg may cause nerve symptoms with prolonged use
  • Long-term 35 mg zinc without copper may impair copper status
  • High niacin intake can cause flushing or digestive effects
  • Biotin can interfere with some laboratory tests

Nutrient quality

69 High impact

Methylfolate, methylcobalamin, several chelated minerals, natural vitamin E, and characterized extracts are strong form choices. High vitamin B6 and niacin doses make the daily profile unnecessarily aggressive.

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Ingredient transparency

78 High impact

Nearly all actives have exact amounts, while one fruit and berry blend lacks component doses. The fruit and berry proprietary blend hides its internal allocation.

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Customer satisfaction

69 High impact

The supplied aggregate rating is very strong. No complaint themes or purpose-specific experience details are supplied.

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Value for money

61 Moderate impact

The unusually broad formula supports some premium value, but aggressive dosing and complexity reduce its practical appeal. Several small specialty extracts add cost without matching the importance of the core nutrients.

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Goals

Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportA- CoverageC+ Formula Quality
Magnesium · 420 mgVitamin B12 · 600 mcgVitamin B6 · 105 mgTaurine · 200 mgGreen Tea · 325 mgFolate · 400 mcg DFEVitamin D · 50 mcg

A substantial magnesium amount, methylfolate, methylcobalamin, taurine, green tea, and grape polyphenols give the copper-free tablet broad cardiovascular relevance. The formula addresses mineral status, homocysteine metabolism, and vascular antioxidant pathways.

Several magnesium forms are useful, although oxide is included and taurine remains modest. Numerous small botanicals and phytonutrients in the copper-free version broaden the label without matching the dose depth of magnesium and B vitamins.

Study evidence
Green Tea Supportive 84 studies
Magnesium Supportive 158 studies
Taurine Supportive 25 studies
Detoxification
Detoxification
Impact
Highest effect
A- Goal FitB Strength of SupportA CoverageB- Formula Quality
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin B6 · 105 mgMolybdenum · 125 mcgSelenium · 200 mcgMagnesium · 420 mgVitamin E · 60 mgZinc · 35 mgVitamin C · 970 mgTaurine · 200 mgRiboflavin · 50 mg

NAC, broccoli compounds, calcium D-glucarate, selenium, molybdenum, vitamin C, silymarin, and betaine create unusually broad detoxification support. The formula addresses glutathione production, conjugation, antioxidant recycling, and liver protection with several meaningful amounts.

The copper-free design pairs a high zinc amount with no copper, which may be unsuitable for prolonged use without attention to total mineral intake. Vitamin B6 is also listed near or above a chronic-use safety ceiling, so long-term daily use alongside other B6 sources may increase neuropathy risk.

Study evidence
Green Tea Disputed 16 studies
Molybdenum Adverse 1 study
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Zinc Supportive 30 studies
General Health
General Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportB+ CoverageC+ Formula Quality
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin D · 50 mcgMagnesium · 420 mgBoron · 3 mgSelenium · 200 mcgTaurine · 200 mgAshwagandha · 125 mgZinc · 35 mgVitamin C · 970 mg

The copper-free formula still offers extensive coverage through vitamins, minerals, antioxidants, and a studied ashwagandha extract. Magnesium, zinc, selenium, vitamin C, vitamin D, and active B vitamins provide substantial foundational support.

Removing copper may suit a specific need, but it weakens mineral balance beside the robust zinc amount. The very high vitamin B6 amount may raise the risk of tingling or numbness during prolonged daily use.

Study evidence
Ashwagandha Supportive 31 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitB+ Strength of SupportA- CoverageC+ Formula Quality
Vitamin D · 50 mcgVitamin E · 60 mgTaurine · 200 mgVitamin C · 970 mgGreen Tea · 325 mg

Standardized green tea EGCG, broccoli concentrate, tart cherry, vitamin C, vitamin D, vitamin E, selenium, zinc, and several polyphenols provide strong multi-pathway support. The direct anti-inflammatory value comes mainly from EGCG and the antioxidant network rather than the many small secondary extracts.

Most key amounts and active constituents are clear, but the formula is extremely crowded. The copper-free design combined with substantial zinc makes long-term stacking with other zinc products a concern.

Study evidence
Apigenin No effect 1 study
Bromelain Supportive 12 studies
Green Tea Mixed 16 studies
Selenium Supportive 34 studies
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B+ Goal FitB+ Strength of SupportA CoverageC+ Formula Quality
Biotin · 3000 mcgNiacin · 190 mg NEVitamin B12 · 600 mcgRiboflavin · 50 mgThiamin · 125 mgVitamin B5 · 600 mgVitamin B6 · 105 mgVitamin D · 50 mcgZinc · 35 mgMagnesium · 420 mgGreen Tea · 325 mg

Green tea, branded chromium, iodine, selenium, magnesium, B vitamins, and Sensoril address fat oxidation, glycemic control, thyroid support, and cellular energy. Several major actives reach useful amounts across distinct metabolic pathways.

The eight-tablet copper-free serving and very broad formula reduce convenience and focus, while the high vitamin B6 amount may raise nerve-symptom risk with prolonged use. Decaffeinated green tea avoids stimulant exposure, but the label does not consistently establish a precise EGCG yield.

Study evidence
Chromium Supportive 47 studies
Green Tea Supportive 31 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Selenium Mixed 28 studies
Vitamin B6 Supportive 16 studies
Stress Relief
Stress Relief
Impact
High effect
A- Goal FitB+ Strength of SupportB+ CoverageC- Formula Quality
Vitamin D · 50 mcgAshwagandha · 125 mgMagnesium · 420 mgFolate · 400 mcg DFEVitamin B12 · 600 mcgVitamin B6 · 105 mgVitamin C · 970 mg

Clinically studied Sensoril ashwagandha and substantial magnesium directly support stress response and nervous-system function. Sensoril has relevant human evidence for perceived stress and cortisol, while magnesium provides established foundational support.

Sensoril is supplied in its usual target range and magnesium is substantial, although the very high vitamin B6 amount raises long-term nerve-damage concern. The branded ashwagandha and mixed glycinate, taurate, citrate, and other magnesium forms are useful, but oxide lowers consistency.

Study evidence
Ashwagandha Supportive 47 studies
Magnesium Supportive 13 studies
Taurine Supportive 5 studies
Vitamin B6 Supportive 10 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene, Vitamin A Acetate)
 1500 mcg RAE
Vitamin C (Acerola Extract, Ascorbic Acid, Ascorbyl Palmitate, Calcium Ascorbate, Magnesium Ascorbate, Niacinamide Ascorbate)
 970 mg
Vitamin D3 (Cholecalciferol)
 50 mcg
Vitamin E (D-Alpha-Tocopherol, D-Alpha-Tocopheryl Succinate)
 67 mg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 125 mg
Riboflavin (Riboflavin 5-Phosphate)
 50 mg
Niacin (Niacinamide, Niacinamide Ascorbate)
 190 mg NE
Vitamin B6
105 mg
Folate (L-5-Methyltetrahydrofolate, Calcium Salt)
 400 mcg DFE
Vitamin B12 (Methylcobalamin)
 600 mcg
Biotin
3000 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 600 mg
Calcium (Calcium Ascorbate, Calcium D-Glucarate, Calcium D-Pantothenate, Dicalcium Phosphate)
 500 mg
Iodine (Potassium Iodide)
 150 mcg
Magnesium (Magnesium Arginate, Magnesium Ascorbate, Magnesium Citrate, Magnesium Glycinate, Magnesium Oxide, Magnesium Taurinate)
 420 mg
Zinc (L-OptiZinc Zinc Mono-L-Methionine Sulfate, Zinc Citrate)
 35 mg
Selenium (Se-Methyl L-Selenocysteine, SelenoExcell High Selenium Yeast, Sodium Selenite)
 200 mcg
Manganese (Manganese Citrate, Manganese Gluconate)
 1 mg
Chromium (Crominex 3+ Chromium)
 500 mcg
Molybdenum (Molybdenum Amino Acid Chelate)
 125 mcg
Potassium (Potassium Citrate)
 35 mg
Broccoli concentrate blend (Broccoli powder, extract, Calcium D-Glucarate)
 725 mg
N-Acetyl-L-Cysteine
600 mg
decaffeinated Green Tea extract (Epigallocatechin Gallate)
 325 mg
Acerola extract
300 mg
Inositol
250 mg
Bitter Orange Citrus Bioflavonoids (Hesperidin)
 200 mg
Fruit/Berry Proprietary Blend
200 mg
Taurine
200 mg
Wild Blueberry Anthocyanin extract
150 mg
Sensoril Ashwagandha extract (Glycoside Conjugates, Oligosaccharides)
 125 mg
Silymarin (Milk Thistle extract)
 100 mg
Trimethylglycine (Betaine Anhydrous)
 100 mg
CherryPure Sour Cherry (Tart Cherry) Proanthocyanidin extract
85 mg
Pomella Pomegranate extract (Punicalagins)
 85 mg
natural Mixed Tocopherols (Alpha-Tocopherol, Beta-Tocopherol, Delta Tocopherol, Gamma-Tocopherol)
 60 mg
MirtoSelect Bilberry extract
30 mg
BioVin Grape Proanthocyanidin extract
25 mg
Leucoselect Grape seed Proanthocyanidin extract
25 mg
Bio-Quercetin Phytosome
15 mg
Bromelain (Pineapple)
 15 mg
Lutein (Marigold extract)
 15 mg
Olive extract (Hydroxytyrosol, Oleuropein, Polyphenols, Tyrosol)
 12.5 mg
Sesame seed Lignan extract
10 mg
Luteolin (Japanese Sophora)
 8 mg
Apigenin
5 mg
Boron (Boron Amino Acid Chelate)
 3 mg
Lycopene (LycoBeads natural Tomato extract)
 3 mg
Delphinidins (Delphinol Maqui berry (Aristotelia chilensis) extract)
 2 mg
Cyanidin-3-Glucoside (Black Currant extract)
 1.25 mg
Adults 18–50
Report overview
Iodine (Potassium Iodide) · 150 mcg OverallScore85
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Potassium iodide supplies a stable and readily absorbed iodine source at a suitable daily amount. The eight-tablet serving adds substantial pill burden and modest dosing risk. Selenium adds relevant cofactor value, while the serving remains expensive.

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Chromium (Crominex 3+ Chromium) · 500 mcg OverallScore82
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

Crominex 3+ provides a recognized, stabilized chromium source with strong quality signals. The disclosed amount reaches the target range for metabolic support, but the label gives only one weight and leaves elemental yield somewhat ambiguous. The active-dose cost is only moderately competitive for chromium-focused use.

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Ashwagandha (Glycoside Conjugates, Oligosaccharides) · 125 mg OverallScore82
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
+6

A clinically studied Sensoril extract is supplied at a dose aligned with its usual target range. No dedicated enhancer is listed for Ashwagandha absorption. The copper-free multinutrient formula serves a specific preference, but its high cost limits Ashwagandha-specific value.

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Adrenal Fatigue Fighter

RidgeCrest Herbals
<p>The lower serving cost makes it the only listed cheaper option, and its listed B6 and niacin amounts are less aggressive than those in the original. A very high pantothenic acid amount and opaque herbal blends remain meaningful trade-offs.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health forBiotin
  2. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  3. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  4. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  5. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  6. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  7. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  8. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  9. Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.
    Ali A; Ma Y; Reynolds J; Wise JP; Inzucchi SE; Katz DL · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2011
    Randomized trial59 participantsMetabolism Boost forChromium
  10. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  11. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males.
    Lopresti AL; Drummond PD; Smith SJ · American journal of men's health · 2020
    Randomized trial57 participantsAnti-Aging forAshwagandha
  12. Green tea and coffee intake and risk of cognitive decline in older adults: the National Institute for Longevity Sciences, Longitudinal Study of Aging.
    Shirai Y; Kuriki K; Otsuka R; Kato Y; Nishita Y; Tange C; Tomida M; Imai T; Ando F; Shimokata H · Public health nutrition · 2021
    Cohort study1,305 participantsAnti-Aging forGreen Tea
  13. Associations of green tea, coffee, and soft drink consumption with longitudinal changes in leukocyte telomere length.
    Sohn I; Shin C; Baik I · Scientific reports · 2023
    Cohort study1,952 participantsAnti-Aging forGreen Tea
  14. Can teatime increase one's lifetime?
    Nakachi K; Eguchi H; Imai K · Ageing research reviews · 2003
    Cohort studyAnti-Aging forGreen Tea
  15. Influences of tea consumption on self-rated health and life satisfaction among older adults: Evidence from the CLHLS.
    Zou M; Sun C; Yang M; Li C; Wang S; Zheng D; Wang J; Yu L; Sun L; Wang Y; Chen H; Zeng Y · PsyCh journal · 2025
    Cohort study78,345 participantsAnti-Aging forGreen Tea
  16. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin.
    Chiu AE; Chan JL; Kern DG; Kohler S; Rehmus WE; Kimball AB · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial40 participantsAnti-Aging forGreen Tea
  17. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsAnti-Aging forZinc
  18. The immune system and the impact of zinc during aging.
    Haase H; Rink L · Immunity & ageing : I & A · 2010
    Narrative reviewAnti-Aging forZinc
  19. Associations between serum trace elements and biological age acceleration in the Chinese elderly: A community-based study investigating the mediating role of inflammatory markers and the moderating effect of physical activity.
    Wang Y; Zhu W; Zhang T; Liu Q; Zou M; Xie Y; Wang M; Wang TS; Pang Y; Jing T; Zhang R · Journal of hazardous materials · 2025
    Observational studyAnti-Aging forZinc
  20. Bidirectional associations of zinc supplement intake with biological ageing interacted by metabolic equivalent of task: A large-scale population-based Biobank study.
    Zhou Y; Zhou J; Li Z; Wang J; Li H; Yin X; Gao J; Wu Y; Li J; Sun YX; Li Y; Wang W; Eser PO; Assimes TL; He J; Chen G · Clinical nutrition (Edinburgh, Scotland) · 2025
    Cross-sectional study68,947 participantsAnti-Aging forZinc
  21. Zinc, metallothioneins, longevity: effect of zinc supplementation on antioxidant response: a Zincage study.
    Mocchegiani E; Zincage Consortium · Rejuvenation research · 2008
    Narrative reviewAnti-Aging forZinc
  22. Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysis.
    Song Y; Manson JE; Buring JE; Sesso HD; Liu S · Journal of the American College of Nutrition · 2005
    Cohort study38,018 participantsAnti-Inflammatory Support forApigenin
  23. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  24. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  25. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  26. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  27. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  28. The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials.
    Kim S; Park TH; Kim WI; Park S; Kim JH; Cho MK · Phytotherapy research : PTR · 2021
    Meta-analysis247 participants5 studies pooledAnti-Inflammatory Support forGreen Tea
  29. Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis.
    Kapoor MP; Sugita M; Fukuzawa Y; Timm D; Ozeki M; Okubo T · Molecules (Basel, Switzerland) · 2021
    Meta-analysis100 participants6 studies pooledAnti-Inflammatory Support Skin Health forGreen Tea
  30. Efficacy of (-)-epigallocatechin gallate delivered by a new-type scaler tip during scaling and root planing on chronic periodontitis: a split-mouth, randomized clinical trial.
    Wang Y; Zeng J; Yuan Q; Luan Q · BMC oral health · 2021
    Randomized trial20 participantsAnti-Inflammatory Support forGreen Tea
  31. Camellia Sinensis Mouthwashes in Oral Care: a Systematic Review.
    Tafazoli A; Tafazoli Moghadam E · Journal of dentistry (Shiraz, Iran) · 2020
    Systematic review69 studies pooledAnti-Inflammatory Support forGreen Tea
  32. Skin photoprotection by green tea: antioxidant and immunomodulatory effects.
    Katiyar SK · Current drug targets. Immune, endocrine and metabolic disorders · 2004
    Narrative reviewAnti-Inflammatory Support forGreen Tea
  33. Selenium and the course of mild Graves' orbitopathy.
    Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
    Randomized trial159 participantsAnti-Inflammatory Support forSelenium
  34. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsAnti-Inflammatory Support Metabolism Boost forSelenium
  35. Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
    Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
    Randomized trial60 participantsAnti-Inflammatory Support forSelenium
  36. The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
    Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
    Meta-analysis656 participants11 studies pooledAnti-Inflammatory Support forSelenium
  37. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
    Randomized trial33 participantsAnti-Inflammatory Support forSelenium
  38. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support Joint Health forVitamin C
  39. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  40. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  41. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  42. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  43. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  44. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  45. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  46. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  47. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  48. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  49. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  50. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  51. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  52. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  53. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  54. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  55. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  56. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  57. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  58. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  59. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  60. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  61. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  62. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  63. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  64. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  65. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  66. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  67. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  68. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  69. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  70. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  71. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  72. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  73. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  74. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  75. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
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    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  77. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  78. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  79. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  80. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  81. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  82. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  83. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  84. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  85. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  86. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  87. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  88. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  89. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  90. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  91. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  92. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  93. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  94. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  95. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  96. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  97. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  98. Antenatal magnesium sulfate and neuroprotection.
    Doyle LW · Current opinion in pediatrics · 2012
    Meta-analysis6,145 participants5 studies pooledBrain Health forMagnesium
  99. No. 376-Magnesium Sulphate for Fetal Neuroprotection.
    Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020
    Guideline / consensus4,446 participantsBrain Health forMagnesium
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    Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA · Obstetrics and gynecology · 2024
    Systematic review5,917 participants6 studies pooledBrain Health forMagnesium
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    Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A · BJOG : an international journal of obstetrics and gynaecology · 2020
    Meta-analysis5,917 participants6 studies pooledBrain Health forMagnesium
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    Chollat C; Marret S · Neural regeneration research · 2020
    Narrative reviewBrain Health forMagnesium
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    Zhang C; Luo J; Yuan C; Ding D · Journal of Alzheimer's disease : JAD · 2021
    Meta-analysis21 studies pooledBrain Health forVitamin B6
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    Itoh K; Kuwabara A; Otsuka R; Sugimoto T; Sakurai T; Niida S; Ao M; Tanaka K; Takenaka S; Kanouchi H · Journal of clinical biochemistry and nutrition · 2025
    Cross-sectional study266 participantsBrain Health forVitamin B6
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    Dhivya K; Sarumathy S; Manigandan G · Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Randomized trial180 participantsBrain Health forVitamin B6
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    Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL · The Journal of nutrition · 2020
    Cohort study949 participantsBrain Health forVitamin B6
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    Iolascon G; Gimigliano R; Bianco M; De Sire A; Moretti A; Giusti A; Malavolta N; Migliaccio S; Migliore A; Napoli N; Piscitelli P; Resmini G; Tarantino U; Gimigliano F · The journal of nutrition, health & aging · 2017
    Scoping review12 studies pooledBrain Health forVitamin B6
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    Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
    Randomized trial69 participantsBrain Health Cognitive Support Detoxification forZinc
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    Randomized trial372 participantsBrain Health Cognitive Support forZinc
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    Marchetti MF; Silva GMD; Freiria CN; Borim FSA; Brito TRP; Milanski M; Corona LP · Ciencia & saude coletiva · 2022
    Cross-sectional study591 participantsBrain Health forZinc
  111. Zinc status, psychological and nutritional assessment in old people recruited in five European countries: Zincage study.
    Marcellini F; Giuli C; Papa R; Gagliardi C; Dedoussis G; Herbein G; Fulop T; Monti D; Rink L; Jajte J; Mocchegiani E · Biogerontology · 2007
    Cross-sectional study853 participantsBrain Health forZinc
  112. Zinc alleviates stroke development through autophagy-mediated modulation of immune microenvironment.
    Qiu Z; Liu X; Li J; Yin H; Luo J; Lin Z; Rexiati M; Abulaiti A; Yasen A; Xing L; Aili D; Meng B; Li X; You Z; He J; Huang C; Qian Z; Chen J · Frontiers in immunology · 2025
    OtherBrain Health forZinc
  113. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
    Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
    Randomized trial240 participantsCardiovascular Support Weight Loss forGreen Tea
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    Zamani M; Kelishadi MR; Ashtary-Larky D; Amirani N; Goudarzi K; Torki IA; Bagheri R; Ghanavati M; Asbaghi O · Frontiers in nutrition · 2023
    Meta-analysis55 studies pooledCardiovascular Support forGreen Tea
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    Yıldırım Ayaz E; Dincer B; Mesci B · Alternative therapies in health and medicine · 2023
    Meta-analysis680 participants9 studies pooledCardiovascular Support Heart Health forGreen Tea
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    Li A; Wang Q; Li P; Zhao N; Liang Z · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2024
    Meta-analysis1,818 participants15 studies pooledCardiovascular Support Heart Health forGreen Tea
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    Pang J; Zhang Z; Zheng TZ; Bassig BA; Mao C; Liu X; Zhu Y; Shi K; Ge J; Yang YJ; Dejia-Huang; Bai M; Peng Y · International journal of cardiology · 2016
    Meta-analysis259,267 participants9 studies pooledCardiovascular Support forGreen Tea
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    Inoue T; Yoshida K; Sasaki E; Aizawa K; Kamioka H · Journal of food science · 2021
    Meta-analysis854 participants11 studies pooledCardiovascular Support forLycopene
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    Yoshida K; Nakazawa Y; Takahashi S; Suzuki S · Food & function · 2025
    Randomized trial75 participantsCardiovascular Support forLycopene
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    Cheng HM; Koutsidis G; Lodge JK; Ashor A; Siervo M; Lara J · Atherosclerosis · 2017
    Meta-analysis21 studies pooledCardiovascular Support forLycopene
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    Cheng HM; Koutsidis G; Lodge JK; Ashor AW; Siervo M; Lara J · Critical reviews in food science and nutrition · 2019
    Meta-analysis25 studies pooledCardiovascular Support forLycopene
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    Song B; Liu K; Gao Y; Zhao L; Fang H; Li Y; Pei L; Xu Y · Molecular nutrition & food research · 2018
    Meta-analysis14 studies pooledCardiovascular Support forLycopene
  123. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
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    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  125. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  126. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  127. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
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    Rayman MP; Stranges S; Griffin BA; Pastor-Barriuso R; Guallar E · Annals of internal medicine · 2011
    Randomized trial501 participantsCardiovascular Support forSelenium
  129. Association of selenium and cadmium with heart failure and mortality based on the National Health and Nutrition Examination Survey.
    Xing X; Xu M; Yang L; Shao C; Wang Y; Qi M; Niu X; Gao D · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Cohort study15,689 participantsCardiovascular Support forSelenium
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    Zhu D; Zhong Q; Lin T; Song T · Frontiers in nutrition · 2023
    Cohort study3,063 participantsCardiovascular Support forSelenium
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    Kuria A; Tian H; Li M; Wang Y; Aaseth JO; Zang J; Cao Y · Critical reviews in food science and nutrition · 2021
    Meta-analysis13 studies pooledCardiovascular Support forSelenium
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    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledCardiovascular Support General Health forSelenium
  133. Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study.
    Sun Q; Wang B; Li Y; Sun F; Li P; Xia W; Zhou X; Li Q; Wang X; Chen J; Zeng X; Zhao Z; He H; Liu D; Zhu Z · Hypertension (Dallas, Tex. : 1979) · 2016
    Randomized trial120 participantsCardiovascular Support Heart Health forTaurine
  134. Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
    Li Y; Wang Q; Liu Y; Li Q; Xia W; Lin S; Yang Q; Scholze A; Zhao Z; He H; Zhang H; Yan Z; Tepel M; Mu H; Zhu Z; Liu D · iScience · 2025
    Randomized trial165 participantsCardiovascular Support Heart Health forTaurine
  135. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Tzang CC; Chi LY; Lin LH; Lin TY; Chang KV; Wu WT; Özçakar L · Nutrition & diabetes · 2024
    Meta-analysis1,024 participants25 studies pooledCardiovascular Support forTaurine
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    Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S · Nutrition reviews · 2025
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    Taddei S; Virdis A; Ghiadoni L; Magagna A; Salvetti A · Circulation · 1998
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  141. Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial.
    Ren J; Liang J; Wang J; Yin B; Zhang F; Li X; Zhu S; Tian H; Cui Q; Song J; Liu G; Ling W; Ma Y · Ecotoxicology and environmental safety · 2022
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    Mullan BA; Young IS; Fee H; McCance DR · Hypertension (Dallas, Tex. : 1979) · 2003
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  143. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
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  145. Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.
    de la Torre R; de Sola S; Hernandez G; Farré M; Pujol J; Rodriguez J; Espadaler JM; Langohr K; Cuenca-Royo A; Principe A; Xicota L; Janel N; Catuara-Solarz S; Sanchez-Benavides G; Bléhaut H; Dueñas-Espín I; Del Hoyo L; Benejam B; Blanco-Hinojo L; Videla S; Fitó M; Delabar JM; Dierssen M; TESDAD study group · The Lancet. Neurology · 2017
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    Liu X; Du X; Han G; Gao W · Oncotarget · 2018
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  147. Investigating the Impact of Tea Consumption on Cognitive Function and Exploring Tea-Genetic Interactions in Older Adults Aged 65-105 Years: Findings from the 2002-2018 CLHLS Data.
    Yu L; Yang M; Ye KX; Li C; Zou M; Wang J; Yuan X; Zheng D; Sun C; Zhang Y; Feng Q; Maier AB; Sun L; Feng L; Wang Y; Chen H; Zeng Y · The journal of prevention of Alzheimer's disease · 2024
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  148. Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline.
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  149. Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study.
    Tomata Y; Sugiyama K; Kaiho Y; Honkura K; Watanabe T; Zhang S; Sugawara Y; Tsuji I · The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
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    Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
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    Zhang C; Sun L; Sun H · Medicine · 2022
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  152. Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
    Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
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  153. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
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  154. Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
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  159. The Effect of Green Tea Extract Supplementation on Liver Enzymes in Patients with Nonalcoholic Fatty Liver Disease.
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  160. Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients: a double-blind placebo-controlled study.
    Sakata R; Nakamura T; Torimura T; Ueno T; Sata M · International journal of molecular medicine · 2014
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  161. Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotype.
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    Chow HH; Hakim IA; Vining DR; Crowell JA; Tome ME; Ranger-Moore J; Cordova CA; Mikhael DM; Briehl MM; Alberts DS · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2007
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  172. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
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  184. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
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    Systematic review84 studies pooledGeneral Health forVitamin D
  229. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  230. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  231. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  232. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  233. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  234. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  235. [Evaluation of the role of dietary intake in the occurrence of alopecia].
    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
    Case-control study272 participantsHair Health forIodine
  236. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  237. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  238. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  239. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  240. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  241. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  242. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  243. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  244. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  245. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  246. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  247. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  248. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  249. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  250. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  251. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  252. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  253. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  254. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  255. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  256. Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials.
    Khalesi S; Sun J; Buys N; Jamshidi A; Nikbakht-Nasrabadi E; Khosravi-Boroujeni H · European journal of nutrition · 2015
    Meta-analysis13 studies pooledHeart Health forGreen Tea
  257. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients.
    Bogdanski P; Suliburska J; Szulinska M; Stepien M; Pupek-Musialik D; Jablecka A · Nutrition research (New York, N.Y.) · 2012
    Randomized trial56 participantsHeart Health forGreen Tea
  258. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials.
    Zheng XX; Xu YL; Li SH; Liu XX; Hui R; Huang XH · The American journal of clinical nutrition · 2011
    Meta-analysis1,136 participants14 studies pooledHeart Health forGreen Tea
  259. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  260. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  261. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
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  262. Seafood diets: hypolipidemic and antiatherogenic effects of taurine and n-3 fatty acids.
    Elvevoll EO; Eilertsen KE; Brox J; Dragnes BT; Falkenberg P; Olsen JO; Kirkhus B; Lamglait A; Østerud B · Atherosclerosis · 2009
    Randomized trial80 participantsHeart Health forTaurine
  263. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.
    Guan L; Miao P · European journal of pharmacology · 2021
    Meta-analysis12 studies pooledHeart Health forTaurine
  264. The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis.
    Waldron M; Patterson SD; Tallent J; Jeffries O · Current hypertension reports · 2019
    Meta-analysis103 participants7 studies pooledHeart Health forTaurine
  265. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  266. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  267. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  268. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  269. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  270. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  271. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  272. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  273. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  274. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  275. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  276. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  277. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  278. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  279. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  280. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  281. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  282. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  283. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  284. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  285. Essentiality of boron for healthy bones and joints.
    Newnham RE · Environmental health perspectives · 1995
    Randomized trial20 participantsJoint Health forBoron
  286. Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study
    Zbigniew Pietrzkowski, Michael J Phelan, Robert Keller, Cynthia Shu, Ruby Argumedo, Tania Reyes-Izquierdo · Clinical Interventions in Aging · 2014
    Randomized trial60 participantsJoint Health forBoron
  287. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis
    Romulus Scorei, Paul Mitrut, Iulian Petrisor, Iulia Scorei · Biological Trace Element Research · 2011
    Randomized trial60 participantsJoint Health forBoron
  288. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  289. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  290. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  291. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  292. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain
  293. Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis.
    Zeng C; Li YS; Wei J; Xie DX; Xie X; Li LJ; Gao SG; Luo W; Xiong YL; Xiao WF; Lei GH · Scientific reports · 2018
    Meta-analysis16 studies pooledJoint Health forMagnesium
  294. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
    Zeng C; Wei J; Terkeltaub R; Yang T; Choi HK; Wang YL; Xie DX; Hunter DJ; Zhang Y; Li H; Cui Y; Li LJ; Lei GH · Arthritis research & therapy · 2018
    Cross-sectional study13,947 participantsJoint Health forMagnesium
  295. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
    Shmagel A; Onizuka N; Langsetmo L; Vo T; Foley R; Ensrud K; Valen P · Osteoarthritis and cartilage · 2019
    Cohort study2,548 participantsJoint Health forMagnesium
  296. Associations of magnesium depletion score with the incidence and mortality of osteoarthritis: a nationwide study.
    Ma R; Zhang C; Liu J; Ren J; Huang H; Wang G; Ding Y; Li X · Frontiers in immunology · 2025
    Observational study19,394 participantsJoint Health forMagnesium
  297. Associations of Dietary Macroelements with Knee Joint Structures, Symptoms, Quality of Life, and Comorbid Conditions in People with Symptomatic Knee Osteoarthritis.
    Zhang Y; Chen T; Luo P; Li S; Zhu J; Xue S; Cao P; Zhu Z; Li J; Wang X; Wluka AE; Cicuttini F; Ruan G; Ding C · Nutrients · 2022
    Cohort study392 participantsJoint Health forMagnesium
  298. Identification for heavy metals exposure on osteoarthritis among aging people and Machine learning for prediction: A study based on NHANES 2011-2020.
    Xia F; Li Q; Luo X; Wu J · Frontiers in public health · 2022
    Cross-sectional studyJoint Health forManganese
  299. Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis
    A. Das Jr., T. A. Hammad · Osteoarthritis and Cartilage · 2000
    Randomized trial93 participantsJoint Health forManganese
  300. Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
    C. T. Leffler, A. F. Philippi, S. G. Leffler, J. C. Mosure, P. D. Kim · Military Medicine · 1999
    Randomized trial34 participantsJoint Health forManganese
  301. Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty.
    Han G; Ye Y; Kang P · Drug design, development and therapy · 2025
    Randomized trial100 participantsJoint Health forVitamin C
  302. Osteoarthritis prevalence and modifiable factors: a population study.
    Plotnikoff R; Karunamuni N; Lytvyak E; Penfold C; Schopflocher D; Imayama I; Johnson ST; Raine K · BMC public health · 2016
    Cross-sectional study4,733 participantsJoint Health forVitamin C
  303. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial.
    Ramón R; Holguín E; Chiriboga JD; Rubio N; Ballesteros C; Ezechieli M · Journal of personalized medicine · 2023
    Randomized trial110 participantsJoint Health forVitamin C
  304. Musculoskeletal manifestations of scurvy.
    Fain O · Joint bone spine · 2005
    Narrative reviewJoint Health forVitamin C
  305. The influence of zinc and iron intake on osteoarthritis patients' subchondral sclerosis progression: A prospective observational study using data from the osteoarthritis Initiative.
    Zheng Z; Luo H; Sun C; Xue Q · Heliyon · 2023
    Cohort study474 participantsJoint Health forZinc
  306. Oral zinc sulphate in rheumatoid arthritis.
    Simkin PA · Lancet (London, England) · 1976
    Randomized trial24 participantsJoint Health forZinc
  307. Psoriatic arthritis treated with oral zinc sulphate.
    Clemmensen OJ; Siggaard-Andersen J; Worm AM; Stahl D; Frost F; Bloch I · The British journal of dermatology · 1981
    Randomized trial24 participantsJoint Health forZinc
  308. Dietary antioxidants and comorbidity of cardiovascular disease and osteoarthritis: A machine learning analysis with SHAP interpretation.
    Sheng G; Liu Y; Dou X; Zhang Y; Zhang J; Zhang D · Medicine · 2026
    Cross-sectional study7,682 participantsJoint Health forZinc
  309. The Daily Intake Levels of Copper, Selenium, and Zinc Are Associated with Osteoarthritis but Not with Rheumatoid Arthritis in a Cross-sectional Study.
    Yang WM; Lv JF; Wang YY; Xu YM; Lin J; Liu J; Chen JJ; Wang XZ · Biological trace element research · 2023
    Cross-sectional study4,200 participantsJoint Health forZinc
  310. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  311. Relationship between Whole-Blood Magnesium and Cognitive Performance among Chinese Adults.
    Lu Z; He R; Zhang Y; Li B; Li F; Fu Y; Rong S · Nutrients · 2023
    Cross-sectional study1,006 participantsMental Focus forMagnesium
  312. Serum Magnesium and Cognitive Function Among Qatari Adults.
    Al-Ghazali K; Eltayeb S; Musleh A; Al-Abdi T; Ganji V; Shi Z · Frontiers in aging neuroscience · 2020
    Cross-sectional study1,000 participantsMental Focus forMagnesium
  313. Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis.
    Effatpanah M; Rezaei M; Effatpanah H; Effatpanah Z; Varkaneh HK; Mousavi SM; Fatahi S; Rinaldi G; Hashemi R · Psychiatry research · 2019
    Meta-analysisMental Focus forMagnesium
  314. The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial.
    Hemamy M; Pahlavani N; Amanollahi A; Islam SMS; McVicar J; Askari G; Malekahmadi M · BMC pediatrics · 2021
    Randomized trial33 participantsMental Focus forMagnesium
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    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsMental Focus Productivity Boost forMagnesium
  316. The Role of Iron and Zinc in the Treatment of ADHD among Children and Adolescents: A Systematic Review of Randomized Clinical Trials.
    Granero R; Pardo-Garrido A; Carpio-Toro IL; Ramírez-Coronel AA; Martínez-Suárez PC; Reivan-Ortiz GG · Nutrients · 2021
    Systematic review9 studies pooledMental Focus forZinc
  317. Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder?
    Arnold LE; Pinkham SM; Votolato N · Journal of child and adolescent psychopharmacology · 2001
    Randomized trialMental Focus forZinc
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    Talebi S; Miraghajani M; Ghavami A; Mohammadi H · Critical reviews in food science and nutrition · 2022
    Meta-analysis489 participants6 studies pooledMental Focus forZinc
  319. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  320. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  321. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium Metabolism Boost forSelenium
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    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
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    Liu K; Zhou R; Wang B; Chen K; Shi LY; Zhu JD; Mi MT · The American journal of clinical nutrition · 2013
    Meta-analysis1,133 participants17 studies pooledMetabolism Boost forGreen Tea
  324. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans.
    Venables MC; Hulston CJ; Cox HR; Jeukendrup AE · The American journal of clinical nutrition · 2008
    Randomized trial23 participantsMetabolism Boost forGreen Tea
  325. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
    Dulloo AG; Duret C; Rohrer D; Girardier L; Mensi N; Fathi M; Chantre P; Vandermander J · The American journal of clinical nutrition · 1999
    Randomized trial10 participantsMetabolism Boost forGreen Tea
  326. A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
    Rondanelli M; Gasparri C; Perna S; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Cavioni A; Mansueto F; Oberto L; Patelli Z; Tartara A; Riva A · Nutrients · 2022
    Randomized trial28 participantsMetabolism Boost forGreen Tea
  327. Epigallocatechin gallate alleviates non-alcoholic fatty liver disease through the inhibition of the expression and activity of Dipeptide kinase 4.
    Yang M; Yan R; Sha R; Wang X; Zhou S; Li B; Zheng Q; Cao Y · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trialMetabolism Boost forGreen Tea
  328. Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
    Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
    Randomized trial163 participantsMetabolism Boost forIodine
  329. Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
    Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
    Single-arm trial51 participantsMetabolism Boost forIodine
  330. Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
    Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
    Cross-sectional study1,197 participantsMetabolism Boost forIodine
  331. Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
    Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
    OtherMetabolism Boost forIodine
  332. Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
    Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
    Non-randomized trial109 participantsMetabolism Boost forIodine
  333. Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
    Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W · Diabetes/metabolism research and reviews · 2021
    Meta-analysis1,168 participants26 studies pooledMetabolism Boost forMagnesium
  334. Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.
    Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Meta-analysis4 studies pooledMetabolism Boost forMagnesium
  335. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
    Meta-analysis384 participants5 studies pooledMetabolism Boost forMagnesium
  336. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
    Rodríguez-Morán M; Guerrero-Romero F · Diabetes care · 2003
    Randomized trial63 participantsMetabolism Boost forMagnesium
  337. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsMetabolism Boost forMagnesium
  338. Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
    Jamilian M; Razavi M; Fakhrie Kashan Z; Ghandi Y; Bagherian T; Asemi Z · Clinical endocrinology · 2016
    Randomized trial70 participantsMetabolism Boost forSelenium
  339. The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Karamali M; Dastyar F; Badakhsh MH; Aghadavood E; Amirani E; Asemi Z · Biological trace element research · 2021
    Randomized trial36 participantsMetabolism Boost forSelenium
  340. Glycemic and lipid responses to selenium-enriched vs. zeaxanthin-enriched eggs in patients with type 2 diabetes: a 12-week randomized controlled trial.
    Niu X; Zhang Y; Liu Y; Zhu Y; Fang B; Hu C; Xu X; Wang R; Sang Y; Zhang Q; Guo J · Frontiers in nutrition · 2026
    Randomized trial58 participantsMetabolism Boost forSelenium
  341. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  342. Dietary one-carbon metabolism nutrients and risk of MASLD progression: a prospective cohort study.
    Shen L; Wang K; Li R; Li Y; Guo Y; Li F; Yuan J; Yang Z; Xia B; Lin X · European journal of clinical nutrition · 2026
    Cohort study46,800 participantsMetabolism Boost forVitamin B6
  343. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
    Kim H; Enrione EB; Narayanan V; Li T; Campa A · Nutrients · 2022
    Cross-sectional study461 participantsMetabolism Boost forVitamin B6
  344. Influence of oral contraceptives, pyridoxine (vitamin B6), and tryptophan on carbohydrate metabolism.
    Adams PW; Wynn V; Folkard J; Seed M · Lancet (London, England) · 1976
    Clinical trial46 participantsMetabolism Boost forVitamin B6
  345. Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
    Rose DP; Leklem JE; Brown RR; Linkswiler HM · The American journal of clinical nutrition · 1975
    Clinical trialMetabolism Boost forVitamin B6
  346. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  347. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  348. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  349. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  350. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  351. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  352. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  353. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  354. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  355. Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.
    Yosaee S; Clark CCT; Keshtkaran Z; Ashourpour M; Keshani P; Soltani S · General hospital psychiatry · 2022
    Meta-analysisMood Support forZinc
  356. Dietary zinc and iron intake and risk of depression: A meta-analysis.
    Li Z; Li B; Song X; Zhang D · Psychiatry research · 2017
    Meta-analysis9 studies pooledMood Support forZinc
  357. Zinc sulphate: A reasonable choice for depression management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.
    Salari S; Khomand P; Arasteh M; Yousefzamani B; Hassanzadeh K · Pharmacological reports : PR · 2016
    Randomized trial43 participantsMood Support forZinc
  358. Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.
    Cheng YC; Huang WL; Chen WY; Huang YC; Kuo PH; Tu YK · Psychological medicine · 2025
    Meta-analysis17,437 participants192 studies pooledMood Support forZinc
  359. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
    Sarris J; Ravindran A; Yatham LN; Marx W; Rucklidge JJ; McIntyre RS; Akhondzadeh S; Benedetti F; Caneo C; Cramer H; Cribb L; de Manincor M; Dean O; Deslandes AC; Freeman MP; Gangadhar B; Harvey BH; Kasper S; Lake J; Lopresti A; Lu L; Metri NJ; Mischoulon D; Ng CH; Nishi D; Rahimi R; Seedat S; Sinclair J; Su KP; Zhang ZJ; Berk M · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2022
    Guideline / consensusMood Support forZinc
  360. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  361. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forZinc
  362. Acute selenium toxicity associated with a dietary supplement.
    MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
    Observational study201 participantsNail Health forSelenium
  363. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  364. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost Sleep Support forAshwagandha
  365. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  366. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC · European journal of nutrition · 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  367. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J · Neuropsychiatric disease and treatment · 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  368. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A · Cureus · 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  369. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J · Journal of the American Medical Directors Association · 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  370. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial.
    Stockfleth E; Beti H; Orasan R; Grigorian F; Mescheder A; Tawfik H; Thielert C · The British journal of dermatology · 2008
    Randomized trial503 participantsSkin Health forGreen Tea
  371. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis.
    Tzellos TG; Sardeli C; Lallas A; Papazisis G; Chourdakis M; Kouvelas D · Journal of the European Academy of Dermatology and Venereology : JEADV · 2011
    Meta-analysis1,247 participants3 studies pooledSkin Health forGreen Tea
  372. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women.
    Heinrich U; Moore CE; De Spirt S; Tronnier H; Stahl W · The Journal of nutrition · 2011
    Randomized trial60 participantsSkin Health forGreen Tea
  373. Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial.
    Zhao H; Zhu W; Zhao X; Li X; Zhou Z; Zheng M; Meng X; Kong L; Zhang S; He D; Xing L; Yu J · JAMA dermatology · 2022
    Randomized trial180 participantsSkin Health forGreen Tea
  374. Systemic and skin-targeting beneficial effects of lycopene-enriched ice cream: A pilot study.
    Chernyshova MP; Pristenskiy DV; Lozbiakova MV; Chalyk NE; Bandaletova TY; Petyaev IM · Journal of dairy science · 2019
    Randomized trialSkin Health forLycopene
  375. Topical lycopene emulgel significantly improves biophysical parameters of human skin.
    Sohail M; Muhammad Faran Ashraf Baig M; Akhtar N; Chen Y; Xie B; Li B · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2022
    Clinical trialSkin Health forLycopene
  376. Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema.
    Aust O; Stahl W; Sies H; Tronnier H; Heinrich U · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2005
    Randomized trialSkin Health forLycopene
  377. Association of Vitamin A Intake With Cutaneous Squamous Cell Carcinoma Risk in the United States.
    Kim J; Park MK; Li WQ; Qureshi AA; Cho E · JAMA dermatology · 2024
    Cohort study123,570 participantsSkin Health forLycopene
  378. β-Carotene and other carotenoids in protection from sunlight.
    Stahl W; Sies H · The American journal of clinical nutrition · 2013
    Narrative reviewSkin Health forLycopene
  379. Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
    Chu AC · Dermatologica · 1985
    Randomized trial38 participantsSkin Health forSelenium
  380. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
    Randomized trial1,312 participantsSkin Health forSelenium
  381. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forSelenium Skin Health forVitamin E Skin Health forZinc
  382. A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
    Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
    Randomized trial121 participantsSkin Health forSelenium
  383. The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
    Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
    Clinical trial31 participantsSkin Health forSelenium
  384. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  385. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  386. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  387. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  388. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  389. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  390. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  391. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  392. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  393. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  394. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  395. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  396. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  397. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  398. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  399. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  400. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  401. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  402. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  403. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  404. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  405. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  406. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  407. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  408. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6
  409. The effects of iron and/or zinc supplementation on maternal reports of sleep in infants from Nepal and Zanzibar.
    Kordas K; Siegel EH; Olney DK; Katz J; Tielsch JM; Kariger PK; Khalfan SS; LeClerq SC; Khatry SK; Stoltzfus RJ · Journal of developmental and behavioral pediatrics : JDBP · 2009
    Randomized trial1,444 participantsSleep Support forZinc
  410. Effect of zinc supplementation on quality of life and sleep quality in young women with premenstrual syndrome: a randomized, double-blind, placebo-controlled trial.
    Jafari F; Tarrahi MJ; Farhang A; Amani R · Archives of gynecology and obstetrics · 2020
    Randomized trial60 participantsSleep Support forZinc
  411. Skin-protective effects of a zinc oxide-functionalized textile and its relevance for atopic dermatitis.
    Wiegand C; Hipler UC; Boldt S; Strehle J; Wollina U · Clinical, cosmetic and investigational dermatology · 2013
    Non-randomized trialSleep Support forZinc
  412. Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011-2016.
    Deng MG; Liu F; Liang Y; Chen Y; Nie JQ; Chai C; Wang K · Journal of affective disorders · 2023
    Cross-sectional study3,660 participantsSleep Support forZinc
  413. Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.
    Al-Musharaf S; Aldhwayan MM; Mazi TA; Abujabir O; Alfawaz W; Aljuraiban GS · Nutrients · 2026
    Cross-sectional study1,041 participantsSleep Support forZinc
  414. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  415. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  416. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  417. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  418. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  419. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  420. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium Stress Relief forVitamin B6
  421. Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical trial.
    Moludi J; Qaisar SA; Kadhim MM; Ahmadi Y; Davari M · Nutrition & metabolism · 2022
    Randomized trial120 participantsStress Relief forTaurine
  422. Effects of taurine supplementation on VDT work induced visual stress.
    Zhang M; Bi LF; Ai YD; Yang LP; Wang HB; Liu ZY; Sekine M; Kagamimori S · Amino acids · 2005
    Randomized trial25 participantsStress Relief forTaurine
  423. Taurine supplementation attenuates delayed increase in exercise-induced arterial stiffness.
    Ra SG; Choi Y; Akazawa N; Ohmori H; Maeda S · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017
    Randomized trial29 participantsStress Relief forTaurine
  424. Correlations between dietary taurine intake and life stress in Korean college students.
    Sung MJ; Chang KJ · Advances in experimental medicine and biology · 2009
    Observational studyStress Relief forTaurine
  425. Profiling inflammatory and oxidative stress biomarkers following taurine supplementation: a systematic review and dose-response meta-analysis of controlled trials.
    Faghfouri AH; Seyyed Shoura SM; Fathollahi P; Shadbad MA; Papi S; Ostadrahimi A; Faghfuri E · European journal of clinical nutrition · 2022
    Meta-analysisStress Relief forTaurine
  426. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsStress Relief forVitamin B6
  427. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  428. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  429. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6
  430. Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledTestosterone Support forAshwagandha
  431. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
    Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
    Randomized trial50 participantsTestosterone Support forAshwagandha
  432. Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
    Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
    Systematic review32 studies pooledTestosterone Support forAshwagandha
  433. Do "testosterone boosters" really increase serum total testosterone? A systematic review.
    Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
    Systematic review3 studies pooledTestosterone Support forAshwagandha
  434. Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
    Randomized trial40 participantsTestosterone Support forAshwagandha
  435. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  436. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  437. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  438. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  439. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  440. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  441. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  442. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  443. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  444. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  445. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  446. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  447. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  448. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  449. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  450. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  451. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C Vision Support forVitamin E
  452. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  453. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
  454. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
    Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
    Cohort study35,551 participantsVision Support forVitamin E
  455. Long-term nutrient intake and 5-year change in nuclear lens opacities.
    Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
    Cohort study408 participantsVision Support forVitamin E
  456. Dietary intake of antioxidants and risk of age-related macular degeneration.
    van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
    Cohort study4,765 participantsVision Support forVitamin E
  457. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  458. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  459. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  460. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  461. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc
  462. Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.
    Pakhale K; Pakhale R; Srivathsan M; Langade J; Langade D · Journal of medicine and life · 2026
    Randomized trial100 participantsWeight Loss forAshwagandha
  463. Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial.
    Choudhary D; Bhattacharyya S; Joshi K · Journal of evidence-based complementary & alternative medicine · 2017
    Randomized trial52 participantsWeight Loss forAshwagandha
  464. Impact of ashwagandha (Withania somnifera L.) supplementation on serum lipid concentrations and anthropometric parameters in adults with overweight and obesity: a double-blind, placebo-controlled pilot study.
    Ballesteros-Torres JM; Vázquez-Aguilar A; Luzardo-Ocampo I; Escalante-Aburto A; Caballero-Prado CJ · Nutrition & metabolism · 2025
    Randomized trial43 participantsWeight Loss forAshwagandha
  465. Adjunctive Ashwagandha (Withania somnifera) Supplementation and Resistance-Training Adaptations in Healthy Adults: A Systematic Review and Random-Effects Meta-Analysis of Muscular Strength, Chest Circumference, and Body Composition.
    Lee JC; Heo AS · Nutrients · 2026
    Meta-analysis161 participants4 studies pooledWeight Loss forAshwagandha
  466. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  467. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsWeight Loss forChromium
  468. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  469. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium
  470. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium
  471. Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial.
    Kobayashi M; Kawano T; Ukawa Y; Sagesaka YM; Fukuhara I · Food & function · 2016
    Randomized trial126 participantsWeight Loss forGreen Tea
  472. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
    Maki KC; Reeves MS; Farmer M; Yasunaga K; Matsuo N; Katsuragi Y; Komikado M; Tokimitsu I; Wilder D; Jones F; Blumberg JB; Cartwright Y · The Journal of nutrition · 2009
    Randomized trial132 participantsWeight Loss forGreen Tea
  473. Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial.
    Xie L; Tang Q; Yao D; Gu Q; Zheng H; Wang X; Yu Z; Shen X · Frontiers in endocrinology · 2022
    Randomized trial62 participantsWeight Loss forGreen Tea
  474. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
    Auvichayapat P; Prapochanung M; Tunkamnerdthai O; Sripanidkulchai BO; Auvichayapat N; Thinkhamrop B; Kunhasura S; Wongpratoom S; Sinawat S; Hongprapas P · Physiology & behavior · 2008
    Randomized trial60 participantsWeight Loss forGreen Tea
  475. Iodine deficiency among Belgian pregnant women not fully corrected by iodine-containing multivitamins: a national cross-sectional survey.
    Vandevijvere S; Amsalkhir S; Mourri AB; Van Oyen H; Moreno-Reyes R · The British journal of nutrition · 2013
    Cross-sectional study1,311 participantsWeight Loss forIodine
  476. Iodine Intake Estimated by 24 h Urine Collection in the Italian Adult Population: 2008-2012 Survey.
    Iacone R; Iaccarino Idelson P; Formisano P; Russo O; Lo Noce C; Donfrancesco C; Macchia PE; Palmieri L; Galeone D; di Lenarda A; Giampaoli S; Strazzullo P · Nutrients · 2021
    Cross-sectional study2,378 participantsWeight Loss forIodine
  477. Iodine intake in adults: Sociodemographic and dietary determinants from a National Health survey.
    Durán-Agüero S; Daga R · Clinical nutrition ESPEN · 2026
    Cross-sectional study1,230 participantsWeight Loss forIodine