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5-HTP

Nature's Way
4.5
★ ★ ★ ★ ★
(847 ratings)
5-HTP 100 mg
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Score91

A well-balanced 100 mg 5-HTP tablet enhanced with Vitamin C and B6 for metabolic support.

How scoring works
Quantity:30 Tablet(s) • (15 servings)
Goals:
Mood Support
Sleep Support
Weight Loss

Score 91

A well-balanced 100 mg 5-HTP tablet enhanced with Vitamin C and B6 for metabolic support.

How scoring works
$10.19($0.67 per serving)
iHerb
$ 11.49
Amazon
$ 10.99
Vitacost
$ 11.49
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Analysis

I often suggest looking for B6 alongside 5-HTP because it acts as a cofactor that helps the brain utilize the amino acid more effectively. The addition of Vitamin C further supports general wellness and neurotransmitter stability, making this a balanced choice for mood support.

It is provided in a tablet format which is sturdy and easy to carry. This is a reliable option for those who want more than just 5-HTP but don't need a massive list of extra herbs.

Pros

  • Includes essential B6 and C cofactors
  • Standardized 100 mg 5-HTP dose
  • Reputable, long-standing brand
  • Clear labeling of ingredients

Cons

  • Higher price per serving than some capsules
  • Tablet format may have more binders

Warnings

  • Take with food to avoid stomach upset
  • Do not combine with other serotonin-boosters

Nutrient quality

93 Highest impact

The inclusion of vitamin B6 and vitamin C facilitates the optimal conversion of the serotonin precursor. A 100mg dose is meaningfully aligned with standard maintenance goals for mood and sleep.

Ingredient transparency

97 Highest impact

Labeling clearly identifies the concentrations of the amino acid and supporting vitamin cofactors. Serving instructions are explicit and provide clear guidance for daily supplementation.

Customer satisfaction

92 Highest impact

Consistent ratings reflect a high degree of user trust in the brand's reliability. Feedback confirms that the addition of cofactors contributes to meaningful improvements in mood and relaxation.

Value for money

81 Highest impact

The cost per serving is higher than budget alternatives, reflecting the premium positioning of the brand. While the cofactors provide value, more efficient options exist for pure milligram content.

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Goals

Mood Support
Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA+ Formula Quality

5-HTP, Vitamin B6, and Vitamin C are pointed out for their synergistic roles in the production of serotonin, a core regulator of mood. The 100 mg dose of 5-HTP per serving aligns with standard clinical recommendations for emotional balance.

Including essential vitamin cofactors ensures that the metabolic conversion from 5-HTP to active serotonin is properly supported. This multi-nutrient approach provides a balanced method for maintaining psychological well-being and stress resilience.

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Sleep Support
Impact
Highest effect
A- Goal FitA Strength of SupportB- CoverageA+ Formula Quality

5-HTP derived from Griffonia supports the endogenous production of serotonin and melatonin for sleep.

Combined with Vitamin B6 and Vitamin C, this 100mg dose appears well aligned with facilitating a balanced nervous system before rest.

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Weight Loss
Impact
High effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality

Appetite regulation and satiety are targeted through 100mg of 5-HTP, supported by vitamins B6 and C. These ingredients facilitate the production and conversion of serotonin, which is clinically shown to help manage food cravings and calorie intake during weight management.

Providing 120mg of ascorbic acid and 8mg of vitamin B6 provides the necessary cofactors for this metabolic pathway. This balanced approach is helpful for individuals who find appetite management to be a major challenge in their weight loss progress.

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Ingredients

IngredientAmount per serving
Total Carbohydrates
1 NP
Vitamin C (Ascorbic Acid)
 120 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 8 mg
5-HTP (Griffonia)
 100 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Children 4+ Vegetarian
Report overview
5-HTP (Griffonia) · 100 mg OverallScore72
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
This multi-nutrient 5-HTP formula includes Vitamin C and B6 to support serotonin synthesis. While it provides an ideal dose and natural source, its higher price-per-serving makes it a premium option.
View ingredientView products
96 Value

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5-HTP Enhanced with Vitamins B6 and C

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5-HTP 100 mg

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Opting for this bulk 120-count supply significantly reduces the daily cost of neurotransmitter precursors. It focuses on the primary active ingredient for those who may already get cofactors from other sources.
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96 Value

5-HTP 100 mg Extra Strength

Swanson
4.8
★★★★★
(7340 ratings)
Choosing this highly-rated 100 mg capsule provides excellent foundational support at a very competitive price. It is a reliable and straightforward alternative for maintaining evening tranquility.
Other sellers (2)
92 Value

Healthy Mood 5-HTP Elite 100 mg Natural Raspberry Flavor

Carlson
4.6
★★★★★
(392 ratings)
Including two forms of Vitamin B6, such as active P-5-P, ensures that the metabolic cofactors are highly bioavailable. It offers superior nutrient forms at a better value than standard vitamin blends.
Other sellers (4)
93 Value

5-HTP 100 mg Time Release

Natrol
4.6
★★★★★
(8263 ratings)
Utilizing time-release technology provides a more sustained delivery of nutrients, which is often preferred for maintaining psychological stability through the day or night. It offers steady support in a single tablet.
Other sellers (2)
94 Performance

5-HTP Plus+ 200 mg

NatureWise
4.5
★★★★★
(5703 ratings)
Using bioactive Pyridoxal 5-Phosphate (P-5-P) as the cofactor is superior for direct metabolic use in the serotonin pathway. The higher 200 mg dose of 5-HTP provides more powerful support for emotional balance.
Other sellers (4)
95 Performance

Double Strength 5-HTP 200 mg

NOW
4.8
★★★★★
(16873 ratings)
A potent blend of 200 mg 5-HTP along with Glycine, Taurine, and Inositol addresses mood and relaxation from multiple neurological angles. This comprehensive formula is more robust for those needing significant support.
Other sellers (4)
96 Performance

5-HTP 200 mg

NutraBio
4.7
★★★★★
(771 ratings)
Combining a double dose of the primary amino acid with high levels of Vitamin B6 maximizes the efficiency of serotonin production. It is a better choice for individuals seeking higher potency and metabolism-focused support.
Other sellers (1)
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