Product Image

Men's Pure Pack

Pure Encapsulations
4.4
★ ★ ★ ★ ★
(28 ratings)
Vanadium 50 mcg
Boron 1 mg
Stinging Nettle 200 mg
Astragalus 50 mg
Saw Palmetto 320 mg
Green Tea 25 mg
Fish Oil 1000 mg
Product Image
Score66
A technically strong but sprawling men’s packet with active B vitamins, magnesium, CoQ10, and prostate botanicals. Eight capsules, premium cost, and undercharacterized fish oil and extracts limit practicality.
How scoring works
Quantity:30 Packet(s) • (30 servings)
Goals:
Cardiovascular Support
Hair Health
Anti-Inflammatory Support
Testosterone Support

Score 66

A technically strong but sprawling men’s packet with active B vitamins, magnesium, CoQ10, and prostate botanicals. Eight capsules, premium cost, and undercharacterized fish oil and extracts limit practicality.
How scoring works
$92.50($3.08 per serving)
Pure Formulas
$ 92.50
Report prices

Analysis

Methylfolate, methylcobalamin, active B6, magnesium citrate, vitamin D3, and natural vitamin E give the nutrient base strong form quality. CoQ10 and prostate-focused saw palmetto, pumpkin oil, nettle, and pygeum add meaningful breadth.

The fish oil does not quantify EPA or DHA, and saw palmetto lacks fatty-acid standardization. Green tea caffeine is not disclosed, while several botanicals are too lightly dosed to justify the packet’s very high serving cost.

The pack fits men who want an all-in-one regimen and accept eight capsules at a time. Focused users can obtain prostate, cardiovascular, or hormone-related ingredients more transparently and efficiently in separate products.

Who is it for
  • Men seeking an all-in-one packet
  • Users who value active B vitamins and magnesium citrate
  • People comfortable taking eight capsules
Best for
  • Broad men’s daily nutrition
  • Prostate-oriented botanicals
  • Combined micronutrients and CoQ10

Pros

  • Uses active folate, B12, and B6
  • Includes magnesium citrate and vitamin D3
  • Provides saw palmetto, pumpkin oil, nettle, and CoQ10

Cons

  • Requires eight capsules
  • Very high serving cost
  • EPA, DHA, caffeine, and several extract details are missing

Warnings

  • Vitamin K intake should remain consistent for people using warfarin.
  • Green tea caffeine is not disclosed, so stimulant-sensitive users cannot plan total caffeine reliably.
  • Saw palmetto may require medical review with hormone-sensitive therapy.
  • Fish oil makes the packet unsuitable for people with fish allergy.

Nutrient quality

75 High impact

Magnesium, CoQ10, saw palmetto, pumpkin oil, nettle, and fish oil have useful amounts, while several antioxidants are token doses. Potentially additive vitamin D, vitamin E, niacin, B6, and fish-oil entries create an aggressive and unclear total load.

Ingredient transparency

70 High impact

Nearly all actives have amounts, but repeated source entries make several totals ambiguous. Only the tiny mixed-carotenoid blend hides component amounts, while the major actives are disclosed.

Customer satisfaction

58 Moderate impact

The favorable rating is based on a small review pool. No review text is available to assess recurring complaints or firsthand results.

Value for money

58 Moderate impact

Premium forms and several substantive actives support quality, but formula crowding limits efficiency. The serving is expensive even after accounting for the multi-product packet format.

Report analysis

Goals

Impact
High effect
B+ Goal FitC+ Strength of SupportB CoverageD+ Formula Quality
Vitamin K · 50 mcgPotassium · 50 mgMagnesium · 250 mgVitamin D · 37.5 mcgCoenzyme Q-10 · 60 mgFish Oil · 1000 mgSelenium · 100 mcgVitamin B12 · 250 mcgVitamin B6 · 10.4 mgVitamin E · 40 mgLycopene · 500 mcgFolate · 667 mcg DFENiacin · 37.5 mgVitamin C · 125 mg

Magnesium, CoQ10, active B vitamins, antioxidant nutrients, and fish oil provide unusually broad cardiovascular coverage. Several forms are favorable, including methylfolate, methylcobalamin, active vitamin B6, and magnesium citrate.

EPA and DHA are not quantified, CoQ10 is moderate, and many plant antioxidants are supplied at small amounts. The large packet includes substantial prostate and general-health ingredients that dilute its cardiovascular focus.

Study evidence
Fish Oil Supportive 185 studies
Magnesium Supportive 123 studies
Vitamin B6 Supportive 35 studies
Impact
High effect
B- Goal FitB- Strength of SupportB CoverageD+ Formula Quality
Biotin · 400 mcgVitamin D · 37.5 mcgZinc · 7.5 mgVitamin C · 125 mg

Saw palmetto, pumpkin oil, nettle, and pygeum create a plausible hormone-focused approach for pattern hair loss. Biotin, vitamin D, zinc, and selenium add nutritional support, although benefits are most likely when a relevant deficiency exists.

The saw palmetto amount is strong, but its fatty-acid standardization and oil-based delivery are not confirmed. A very broad packet adds many general-health ingredients that do not materially strengthen hair support.

Study evidence
Biotin Supportive 4 studies
Saw Palmetto Supportive 5 studies
Selenium Disputed 7 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Anti-Inflammatory Support
Impact
Moderate effect
B+ Goal FitD Strength of SupportC+ CoverageD Formula Quality
Vitamin D · 37.5 mcgFish Oil · 1000 mgCoenzyme Q-10 · 60 mgVitamin E · 40 mgVitamin C · 125 mgGreen Tea · 25 mg

Fish oil, nettle, green tea markers, CoQ10, vitamin D, vitamin E, and other antioxidants provide wide anti-inflammatory coverage. Several ingredients have useful amounts, but EPA, DHA, and specific EGCG are not disclosed.

The packet combines lipid mediators, antioxidant defense, immune modulation, and botanical signaling. Its very large ingredient list and numerous general-health components dilute focus and leave important actives undercharacterized.

Study evidence
Fish Oil Supportive 68 studies
Green Tea Mixed 16 studies
Stinging Nettle Supportive 5 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Impact
Moderate effect
C Goal FitC- Strength of SupportC CoverageD Formula Quality
Magnesium · 250 mgZinc · 7.5 mgVitamin D · 37.5 mcgBoron · 1 mgFish Oil · 1000 mg

Vitamin D3, magnesium, zinc, boron, nettle, and maca cover several endocrine-related pathways. Most goal-specific ingredients are modest, and the formula is primarily a comprehensive men’s health packet.

Strong nutrient forms improve quality, while low zinc, low boron, uncharacterized nettle, and undisclosed EPA and DHA limit effective depth. Saw palmetto and other prostate-focused ingredients further blur the testosterone goal.

Study evidence
Boron Disputed 3 studies
Fish Oil Supportive 3 studies
Magnesium Disputed 5 studies
Vitamin D Supportive 56 studies
Zinc Disputed 7 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
2 Gram(s)
Cholesterol
5 mg
Vitamin A (Beta-Carotene)
1125 mcg
Vitamin C (Ascorbic Acid)
125 mg
Vitamin D (Cholecalciferol, Vitamin D3)
37.5 mcg
Vitamin E (D-Alpha-Tocopherol Succinate, Tocopherol)
40 mg
Vitamin K (Vitamin K1)
50 mcg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
12.5 mg
Riboflavin (Riboflavin 5' Phosphate)
17.35 mg
Niacin (Niacinamide)
37.5 mg
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
10.4 mg
Folate (Metafolin)
667 mcg DFE
Vitamin B12 (Methylcobalamin)
250 mcg
Biotin
400 mcg
Pantothenic Acid (Calcium Pantothenate, Vitamin B5)
25 mg
Choline (Choline Bitartrate)
20 mg
Calcium (Calcium Citrate)
100 mg
Iodine (Potassium Iodide)
100 mcg
Magnesium (Magnesium Citrate)
250 mg
Zinc (Zinc Citrate)
7.5 mg
Selenium (Selenium Yeast)
100 mcg
Manganese (Manganese Citrate)
1 mg
Chromium (Chromium Polynicotinate)
100 mcg
Potassium (Potassium Citrate)
50 mg
Boron Glycinate
1 mg
Vanadium (Bis-Glycinato OxoVanadium)
50 mcg
Proprietary Mixed Carotenoid Blend
212 mcg
Inositol
62.5 mg
Alpha Lipoic Acid
37.5 mg
Coenzyme Q10
60 mg
FloraGLO Lutein
3 mg
Zeaxanthin
500 mcg
Lycopene
500 mcg
Green Tea (Camellia sinensis) extract (Epigallocatechin, total Tea Catechins)
25 mg
Red Wine Grape (Vitis vinifera) concentrate (total Polyphenols)
50 mg
Grape (Vitis vinifera) extract (Polyphenols)
50 mg
Pomegranate (Punica granatum) extract (Punicosides)
25 mg
Maca (Lepidium meyenii) extract
100 mg
Astragalus (Astragalus membranaceus) extract
50 mg
Saw Palmetto (Serenoa repens) extract
320 mg
Pumpkin (Cucurbita pepo) Oil
320 mg
Nettle (Urtica dioica) extract
200 mg
Pygeum (Pygeum africanum) extract
45 mg
Fish Oil concentrate (Anchovies, Mackerel, Sardines)
1000 mg
Gluten Free Men 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Bis-glycinato oxovanadium is an advanced organic complex with strong form quality. The 50 mcg amount is moderate and clearly disclosed, while an eight-capsule packet adds a substantial pill burden. No manufacturing or testing standard is provided, and serving value is poor.

Boron · 1 mg OverallScore48
C Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Boron glycinate offers a useful organic chelate, but no premium source verification is provided. The 1 mg amount is below maintenance and clinical target ranges but not entirely negligible. A very high packet cost and low boron amount make it inefficient for boron-focused use.

Stinging Nettle · 200 mg OverallScore46
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

A near-median nettle extract amount appears alongside several prostate-focused actives. The label does not identify root or give a concentration ratio, so alignment and potency remain uncertain. Very high serving cost and a large packet burden make the nettle component poor value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Regular use of fish oil supplements and course of cardiovascular diseases: prospective cohort study.
    Chen G; Qian ZM; Zhang J; Zhang S; Zhang Z; Vaughn MG; Aaron HE; Wang C; Lip GY; Lin H · BMJ medicine · 2024
    Cohort study415,737 participantsCardiovascular Support forFish Oil
  2. Marine n-3 fatty acid treatment for carotid plaques in patients with type 2 diabetes.
    Zhuang P; Liu X; Jia W; Zheng W; Wan X; Chen W; Gu J; Li Y; Lan X; Li H; Tong W; Wu Y; Wu X; Ao Y; Ye H; Wu F; Zhu L; Zhang L; Li Y; Meng D; Tian Y; Wang A; Wu S; Zhu F; Zhang Y; Shi H; Yu X; Zhang F; Zhang Y; Jiao J · Cardiovascular diabetology · 2026
    Randomized trial415 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  5. Vitamin D, Marine n-3 Fatty Acids, and Primary Prevention of Cardiovascular Disease Current Evidence.
    Manson JE; Bassuk SS; Cook NR; Lee IM; Mora S; Albert CM; Buring JE; VITAL Research Group · Circulation research · 2020
    Randomized trial25,871 participantsCardiovascular Support forFish Oil
  6. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  7. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  8. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  9. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  10. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  11. The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials.
    Kim S; Park TH; Kim WI; Park S; Kim JH; Cho MK · Phytotherapy research : PTR · 2021
    Meta-analysis247 participants5 studies pooledAnti-Inflammatory Support forGreen Tea
  12. Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis.
    Kapoor MP; Sugita M; Fukuzawa Y; Timm D; Ozeki M; Okubo T · Molecules (Basel, Switzerland) · 2021
    Meta-analysis100 participants6 studies pooledAnti-Inflammatory Support forGreen Tea
  13. Efficacy of (-)-epigallocatechin gallate delivered by a new-type scaler tip during scaling and root planing on chronic periodontitis: a split-mouth, randomized clinical trial.
    Wang Y; Zeng J; Yuan Q; Luan Q · BMC oral health · 2021
    Randomized trial20 participantsAnti-Inflammatory Support forGreen Tea
  14. Camellia Sinensis Mouthwashes in Oral Care: a Systematic Review.
    Tafazoli A; Tafazoli Moghadam E · Journal of dentistry (Shiraz, Iran) · 2020
    Systematic review69 studies pooledAnti-Inflammatory Support forGreen Tea
  15. Skin photoprotection by green tea: antioxidant and immunomodulatory effects.
    Katiyar SK · Current drug targets. Immune, endocrine and metabolic disorders · 2004
    Narrative reviewAnti-Inflammatory Support forGreen Tea
  16. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  17. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  18. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  19. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  20. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  21. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  22. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  23. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  24. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  25. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  26. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  27. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  28. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  29. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  30. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  31. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  32. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  33. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  34. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  35. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  36. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support forMagnesium
  37. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support forMagnesium
  38. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  39. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
    Cohort studyCardiovascular Support forVitamin B6
  40. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  41. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  42. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsCardiovascular Support forVitamin B6
  43. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6
  44. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  45. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  46. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  47. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  48. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  49. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  50. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  51. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  52. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  53. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  54. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  55. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  56. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  57. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  58. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  59. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  60. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  61. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  62. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  63. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  64. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  65. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  66. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  67. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  68. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  69. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  70. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  71. Dietary supplementation with docosahexaenoic acid rich fish oil increases circulating levels of testosterone in overweight and obese men.
    Abbott K; Burrows TL; Acharya S; Thota RN; Garg ML · Prostaglandins, leukotrienes, and essential fatty acids · 2021
    Randomized trial61 participantsTestosterone Support forFish Oil
  72. Fish oil produces an atherogenic lipid profile in hypertensive men.
    Hughes GS; Ringer TV; Watts KC; DeLoof MJ; Francom SF; Spillers CR · Atherosclerosis · 1991
    Randomized trial26 participantsTestosterone Support forFish Oil
  73. Associations of Fish Oil Supplement Use With Testicular Function in Young Men.
    Jensen TK; Priskorn L; Holmboe SA; Nassan FL; Andersson AM; Dalgård C; Petersen JH; Chavarro JE; Jørgensen N · JAMA network open · 2020
    Cross-sectional study1,679 participantsTestosterone Support forFish Oil
  74. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  75. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  76. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  77. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  78. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  79. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  80. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  81. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  82. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  83. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D
  84. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  85. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  86. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  87. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  88. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc