St. John's Wort 375 mg
Swanson Premium Brand
St. John's Wort 375 mg
4.7
★ ★ ★ ★ ★
(2868 ratings)
St. John's Wort 375 mg
Score 60.0
An extremely budget-friendly whole herb St. John's Wort option from a popular brand, offering good value per serving but lacking explicit extract standardization.
Quantity: 60 Capsule(s)Servings size: 1 Capsule(s) (60 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 60.0
An extremely budget-friendly whole herb St. John's Wort option from a popular brand, offering good value per serving but lacking explicit extract standardization.
insights Analysis
This Swanson product offers a very economical entry point into St. John's Wort supplementation at just $0.04 per serving. While its 375mg dose is of the whole herb and not specified as a standardized extract, which nutritionists often prefer for consistent potency, it provides a foundational amount of the herb. The high review count suggests consumer satisfaction with its value proposition. However, users may need to take multiple servings to reach doses typically associated with clinical efficacy for mood support.
- Very low price per serving
- High number of positive reviews
- From a reputable brand
- Not a standardized extract
- Dosage (375mg) is on the lower side for potential efficacy if not an extract
- St. John's Wort can interact with numerous medications, including antidepressants, birth control, and blood thinners. Consult a healthcare professional before use, especially if on other medications.
- Photosensitivity may occur.
$2.59($0.04 per serving)
 iHerb | $ 2.59 |
bolt Effectiveness for goals
Some research suggests St. John's Wort may be effective for mild to moderate depression. Its use for severe depression is not well-supported by evidence. Consultation with a healthcare professional is advisable before considering use.
For mild to moderate depression, some studies suggest St. John's Wort can be similarly effective to certain conventional antidepressants. However, it may have a different side effect profile and significant drug interactions. This comparison does not extend to all types or severities of depression.
Scientific research indicates that St. John's Wort extracts can be effective for treating mild to moderate depression, often showing comparable efficacy to some standard antidepressants. However, results can vary depending on the extract used and the specific study design. Research on its effectiveness for other conditions is less conclusive.
For mild to moderate depression, some studies suggest St. John's Wort may be as effective as certain prescription antidepressants. However, results can vary, and it is not generally recommended as a substitute for standard care for severe depression.
Clinical studies indicate that St. John's Wort can be effective for relieving symptoms of mild depression. Its efficacy in this context has been compared to that of some conventional antidepressants. However, individual responses may vary.
schedule Dosage, timing & forms
Common dosages of St. John's Wort extract often range from 300 mg to 900 mg per day. These dosages typically provide standardized amounts of active compounds like hypericin or hyperforin. It's important to check the product label for specific recommendations.
The effects of St. John's Wort are generally not immediate and may take several weeks to become noticeable. Individuals typically report feeling benefits after two to four weeks of consistent daily use. It's important to continue taking it as directed for the recommended duration.
The effects of St. John's Wort are typically not immediate and may take several weeks to become noticeable. Individuals often report initial changes within 2 to 4 weeks, with more pronounced benefits potentially appearing after 4 to 6 weeks of consistent use. This gradual onset is common for many herbal supplements.
Common dosages for St. John's Wort extracts, often standardized to hypericin or hyperforin, typically range from 300 mg to 900 mg per day. These doses are usually divided into two or three administrations throughout the day. The specific dosage can vary based on the extract's standardization and the product's concentration.
St. John's Wort is typically taken two to three times per day. Dividing the daily dose helps maintain consistent levels of its active compounds in the body. Always follow the specific instructions provided on the supplement's label or by a qualified healthcare professional.
health_and_safety Safety & interactions
No, St. John's Wort should not be taken with antidepressant medications, especially selective serotonin reuptake inhibitors (SSRIs). Combining them can lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high fever. Always consult a healthcare professional before combining St. John's Wort with any prescription drugs.
Yes, St. John's Wort can interact significantly with many antidepressant medications. This interaction may lead to a serious condition called serotonin syndrome, which involves symptoms like confusion, rapid heart rate, and high blood pressure. It is crucial to consult a healthcare professional before combining St. John's Wort with any antidepressant.
St. John's Wort can interact significantly with many medications, reducing their effectiveness or increasing side effects. Common side effects may include photosensitivity, upset stomach, fatigue, and restlessness. It is important to discuss its use with a healthcare provider.
Yes, St. John's Wort significantly interacts with medications used for HIV/AIDS (e.g., protease inhibitors, NNRTIs) and immunosuppressants used after organ transplantation (e.g., cyclosporine). It can dramatically reduce the levels and effectiveness of these critical drugs. Such combinations are generally contraindicated and should be strictly avoided.
Yes, St. John's Wort is known to reduce the effectiveness of hormonal contraceptives, including birth control pills. This interaction can potentially lead to unintended pregnancy. It is recommended to use an alternative or additional method of contraception while taking St. John's Wort.
Ingredients
| Ingredient | Amount per serving |
|---|---|
St. John's Wort | 375 mg |
Categories
St. John's Wort 60.0
As a whole herb product without standardization, it is a less refined form of St. John's Wort compared to standardized extracts available. However, its extremely low price makes it an accessible entry point for those seeking the herb.
Goals
Mood Support 60.0
While St. John's Wort is known for mood support, this product is an unstandardized whole herb at a relatively low dose (375mg), which may not provide consistent or strong enough effects compared to standardized extracts or higher doses.
Stress Relief 55.0
Similar to mood support, the unstandardized nature and lower dosage might mean less predictable outcomes for significant stress relief compared to more potent, standardized alternatives.
Sleep Support 50.0
St. John's Wort's effect on sleep is often indirect, improving sleep by alleviating mood or stress issues. This product's unstandardized form and lower dosage may yield limited direct sleep benefits.
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