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Adrenal Response

Innate Response Formulas
4.8
★ ★ ★ ★ ★
(52 ratings)
Ashwagandha 250 mg
Rhodiola
Astragalus 150 mg
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Score66
A strong Sensoril-and-rhodiola core supports a credible adaptogen formula. Opaque extras and premium cost weaken an otherwise useful design.
How scoring works
Quantity:90 Tablet(s) • (45 servings)
Goals:
Stress Relief
Brain Health
Mood Support
Energy
Cognitive Support
Productivity Boost
Mental Focus

Score 66

A strong Sensoril-and-rhodiola core supports a credible adaptogen formula. Opaque extras and premium cost weaken an otherwise useful design.
How scoring works
$57.99($1.28 per serving)
Pure Formulas
$ 57.99
Walmart
$ 63.79
Vitacost
$ 57.99
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Analysis

Sensoril ashwagandha is supplied at a well-aligned amount, while rhodiola, holy basil, astragalus, and schisandra broaden the stress-response strategy. The pairing is relevant to stress-related energy, mood, and mental stamina.

Rhodiola lacks rosavin and salidroside values, while astragalus has limited identity and extract information. A separate foods-and-extracts blend hides its individual contents and amounts, adding uncertainty without clear benefit.

The formula may suit people who value the branded ashwagandha core and broad botanical support. High serving cost and opaque extras make it less attractive than a simpler standardized blend.

Who is it for
  • Adults seeking branded Sensoril ashwagandha
  • Users wanting broad stress support
  • People comfortable with a multi-herb tablet
Best for
  • Stress resilience
  • Mood and energy support under pressure
  • Users prioritizing a studied ashwagandha extract

Pros

  • Well-aligned Sensoril amount
  • Practical rhodiola dose
  • Holy basil and schisandra add relevant breadth

Cons

  • Additional foods-and-extracts blend is opaque
  • Rhodiola markers are not stated
  • High serving cost

Warnings

  • Ashwagandha warrants professional guidance during pregnancy or when thyroid or liver concerns are present.
  • Rhodiola, eleuthero, or ginseng may feel stimulating and can be a poor fit near bedtime or with other stimulants.
  • Introduce multi-herb adaptogen blends cautiously because sensitivity to one ingredient can be difficult to identify.

Nutrient quality

81 Highest impact

Sensoril is a well-characterized ashwagandha extract, while several other botanicals lack marker standardization. Sensoril and rhodiola have meaningful amounts, with the supporting botanicals present at moderate levels.

Ingredient transparency

64 Moderate impact

The main botanicals have individual amounts, but the foods-and-extracts component is only disclosed as a total. Non-active tablet ingredients are not provided.

Customer satisfaction

64 Moderate impact

The supplied average rating is very strong. The small rating sample limits confidence in the average.

Value for money

51 Moderate impact

A strong Sensoril and rhodiola core adds quality, though incomplete characterization limits the premium formula. The high serving cost weakens value despite meaningful lead adaptogen amounts.

Report analysis

Goals

Stress Relief
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageA- Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha and Rhodiola rosea form a strong adaptogen core for perceived stress and stress-related fatigue. Holy basil, schisandra, and astragalus broaden resilience support without adding stimulants.

Rhodiola lacks active-marker standardization, and the additional food blend is not broken down. The formula is coherent but concentrates on adaptogens rather than direct inhibitory-neurotransmitter support.

Study evidence
Ashwagandha Supportive 47 studies
Rhodiola Supportive 16 studies
Brain Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha and Rhodiola rosea provide a well-aligned adaptogenic base for stress resilience and mental fatigue. Astragalus, holy basil, and schisandra add broader stress-response support.

Rhodiola marker percentages and several botanical standardization details are missing, while the extra blend is not individually disclosed. It is a coherent adaptogen formula but does not address memory, membrane health, or neuronal energy directly.

Study evidence
Ashwagandha Supportive 12 studies
Rhodiola Supportive 8 studies
Mood Support
Impact
Highest effect
A- Goal FitB Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha and rhodiola directly support stress resilience and stress-related fatigue. Holy basil, schisandra, and astragalus broaden adaptogenic support, though most act through overlapping stress-response pathways.

The two leading adaptogens have meaningful amounts, but rhodiola lacks active-marker standardization and several supporting extracts are incompletely characterized. The formula is coherent for stress-related mood strain, with less relevance to serotonin or structural brain support.

Study evidence
Ashwagandha Supportive 29 studies
Rhodiola Supportive 15 studies
Energy
Impact
Highest effect
A- Goal FitB+ Strength of SupportB CoverageB+ Formula Quality

Rhodiola and ashwagandha directly support stress resilience and may reduce fatigue linked to sustained pressure. Sensoril ashwagandha and clinically relevant rhodiola have useful human evidence, while the other adaptogens are less consistently supported.

Sensoril at 250 mg and rhodiola at 200 mg are meaningful, with the remaining herbs supplied at moderate supporting amounts. The branded ashwagandha is well specified, but rhodiola lacks rosavin and salidroside standardization and one blend hides its details.

Study evidence
Ashwagandha Supportive 9 studies
Rhodiola Supportive 18 studies
Cognitive Support
Impact
Highest effect
B+ Goal FitB Strength of SupportB CoverageB+ Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha and rhodiola directly target stress-related fatigue and cognitive strain. Holy basil, schisandra, and astragalus broaden resilience support without adding acute stimulation.

The lead adaptogens reach useful amounts, though rhodiola active-marker percentages are missing. A small mixed-food blend is not transparent enough to add confidence.

Study evidence
Ashwagandha Supportive 17 studies
Rhodiola Supportive 7 studies
Productivity Boost
Impact
High effect
B+ Goal FitB Strength of SupportB CoverageB- Formula Quality

The adaptogen blend is well aligned with productivity during sustained stress and mental fatigue. Sensoril ashwagandha and rhodiola reach useful amounts, with holy basil and schisandra adding broader stress support.

The main doses are disclosed, but rhodiola marker standardization and the additional food blend remain unclear. The formula does not provide a direct stimulant or neurotransmitter precursor for immediate task focus.

Study evidence
Ashwagandha Supportive 6 studies
Rhodiola Supportive 7 studies
Mental Focus
Impact
High effect
B- Goal FitB Strength of SupportB- CoverageB Formula Quality

Sensoril ashwagandha and Rhodiola rosea provide a solid adaptogen base for mental stamina under stress. Both use amounts that align reasonably with common human research, although rhodiola marker standardization is not shown.

Holy basil, schisandra, and astragalus broaden stress support but do not create an acute alertness or neurotransmitter pathway. A small foods-and-extracts blend reduces transparency, while the named primary botanicals remain individually disclosed.

Study evidence
Ashwagandha Supportive 12 studies
Rhodiola Supportive 15 studies

Ingredients

IngredientAmount per serving
Sensoril Ashwagandha root & leaf extract
250 mg
Rhodiola rosea root extract
200 mg
Astragalus
150 mg
Holy Basil
150 mg
Schisandra
100 mg
Additional Foods & Extracts
145 mg
Gluten Free Adults 18–50 Kosher Dairy Free Vegetarian
Report overview
Ashwagandha · 250 mg OverallScore80
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

A clinically studied Sensoril extract is supplied at a well-aligned dose. The label clearly states the amount, though it lacks a dedicated absorption aid. A substantial cost premium and the multi-ingredient focus weaken its value as a dedicated ashwagandha choice.

Rhodiola · 200 mg OverallScore61
C Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Rhodiola rosea root extract is clearly identified at an amount aligned with common clinical use. Missing rosavin and salidroside standardization leaves potency consistency uncertain. Value for Rhodiola cannot be established, and the supplied facts omit other ingredients.

Astragalus · 150 mg OverallScore35
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

The 150 mg amount is clearly stated, but the label does not identify an extract, root, species, or active-marker standardization. That limited identity and potency detail makes the ingredient hard to compare with well-characterized astragalus extracts. Cost efficiency is weak for astragalus alone because the serving price covers a broader adaptogen blend.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  2. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  3. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  4. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  5. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Stress Relief forAshwagandha
  6. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  7. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  8. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  9. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health Productivity Boost forRhodiola
  10. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  11. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  12. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  13. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  14. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  15. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support Stress Relief forRhodiola
  16. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  17. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy Mood Support forAshwagandha
  18. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  19. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  20. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy Productivity Boost forAshwagandha
  21. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  22. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  23. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  24. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy Stress Relief forRhodiola
  25. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  26. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  27. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  28. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  29. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  30. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  31. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  32. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  33. Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
    Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
    Meta-analysis1,049 participants2 studies pooledMood Support forRhodiola
  34. The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
    Clinical trial10 participantsMood Support forRhodiola
  35. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
    Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
    Systematic review66 studies pooledMood Support forRhodiola
  36. Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
    Moragrega I; Ríos JL · Planta medica · 2022
    Systematic reviewMood Support forRhodiola
  37. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
    Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
    Single-arm trial118 participantsMood Support forRhodiola
  38. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledProductivity Boost forAshwagandha
  39. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost forAshwagandha
  40. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  41. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialProductivity Boost forRhodiola
  42. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewProductivity Boost Stress Relief forRhodiola
  43. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  44. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  45. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  46. Stress management and the role of Rhodiola rosea: a review.
    Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
    Narrative reviewStress Relief forRhodiola
  47. Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
    Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
    Narrative reviewStress Relief forRhodiola