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Pharma GABA 100 mg

Natural Factors Stress-Relax
4.5
★ ★ ★ ★ ★
(5133 ratings)
GABA 200 mg
Product Image
Score81
A focused fermented PharmaGABA product delivering 200 mg in a two-tablet chewable. The product title states 100 mg while the supplied serving data state 200 mg.
How scoring works
Quantity:60 Tablet(s) • (30 servings)
Goals:
Stress Relief
Sleep Support
Mood Support

Score 81

A focused fermented PharmaGABA product delivering 200 mg in a two-tablet chewable. The product title states 100 mg while the supplied serving data state 200 mg.
How scoring works

Also available as

1 option
120 servings GABA 200 mg • 120 Tablet(s) • 60 servings $40.59 ($0.67 per serving)
$23.09($0.76 per serving)
Vitacost
$ 23.09
Pure Formulas
$ 23.09
Vitacost
$ 23.09
iHerb
$ 23.09
Amazon
$ 23.09
iHerb
$ 23.09
Report prices

Analysis

The two-tablet chewable supplies 200 mg of fermented PharmaGABA. The formula also has four grams of carbohydrate per serving.

PharmaGABA provides a clearly identified fermented source at a practical calming amount. A branded source improves ingredient confidence, although individual response to oral GABA can still vary.

The main limitation is that the product title states 100 mg while the supplied serving data state 200 mg. The product fits adults who prefer a chewable fermented GABA product, provided sedative stacking and next-day drowsiness are considered.

Who is it for
  • adults who prefer a chewable fermented GABA product
  • people seeking focused relaxation support without a multi-herb blend
Best for
  • evening relaxation
  • supporting a calmer bedtime routine

Pros

  • Clearly states 200 mg of GABA
  • Two-tablet chewable is easy to use
  • Uses a named fermented PharmaGABA source

Cons

  • The product title states 100 mg while the supplied serving data state 200 mg
  • Oral GABA effects may differ substantially between users
  • Chewable serving contributes four grams of carbohydrate

Warnings

  • The chewable serving contributes four grams of carbohydrate.
  • Verify the original label because the product title and supplied serving data show different GABA amounts.
  • GABA may cause drowsiness, dizziness, or reduced alertness.
  • Alcohol, sleep medicines, benzodiazepines, antihistamines, or other sedatives may intensify drowsiness when combined with GABA.

Nutrient quality

89 Highest impact

Branded fermented PharmaGABA and chewable delivery provide strong form quality. The GABA amount is meaningful for focused calming support, and the formula offers focused calming support through one primary pathway.

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Ingredient transparency

86 Highest impact

Every listed active has a specific amount and no proprietary blend obscures the formula. Complete intake directions and inactive ingredients are not supplied, leaving part of the label unverified.

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Customer satisfaction

71 High impact

The supplied aggregate satisfaction level is strong. The extensive feedback volume makes the aggregate dependable.

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Value for money

71 High impact

Premium form quality only partly supports the high cost. The serving is expensive for a single calming active, and other premium-form GABA products offer stronger value.

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Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA Formula Quality
GABA · 200 mg

Branded fermented GABA provides focused support for inhibitory signaling and may help with short-term feelings of tension. The chewable format may aid oral absorption, although evidence for supplemental GABA remains less settled than for leading stress ingredients.

The active amount is clearly disclosed and well targeted for a premium GABA product. GABA may add to the effects of alcohol, sleep medicines, or other sedatives and can reduce alertness, so caution is warranted before driving.

Study evidence
GABA Supportive 6 studies
Sleep Support
Sleep Support
Impact
High effect
C- Goal FitB+ Strength of SupportC- CoverageA- Formula Quality

Branded PharmaGABA at 200 mg provides a clearly disclosed relaxation ingredient with better source transparency than generic GABA. Direct evidence for oral GABA improving sleep remains limited despite the fermented branded form.

The chewable tablet gives one calming pathway useful depth but does not address circadian timing or mineral support. The chewable base adds carbohydrates without strengthening the sleep mechanism.

Study evidence
GABA Supportive 4 studies
Mood Support
Mood Support
Impact
Moderate effect
D- Goal FitB- Strength of SupportF CoverageB- Formula Quality

Oral PharmaGABA may promote calm, but evidence for sustained mood regulation is limited. The 200 mg amount is clearly disclosed and is not hidden in a blend.

Oral GABA has uncertain access to the brain, which limits confidence in a direct neurotransmitter effect. The single-ingredient formula is focused but covers no stress-adaptation or anti-inflammatory pathway.

Study evidence
GABA Supportive 12 studies

Ingredients

IngredientAmount per serving
Calories
10 mg
Total Carbohydrates
4 grams
Pharma GABA
200 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
GABA · 200 mg OverallScore84
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

The 200 mg fermented PharmaGABA amount suits premium calming use, but the serving cost is high. Chewable delivery may support absorption through the mouth, and no artificial additive is disclosed in the supplied ingredients. PharmaGABA may add to the effects of alcohol or sedating medicines and reduce alertness.

View ingredientView products
Loading alternative details
74 Performance

Liposomal GABA

Quicksilver Scientific
<p>240 mg GABA with 100 mg L-theanine and phosphatidylcholine broadens the original's single-ingredient approach and may better support relaxation through complementary pathways. The supplied data do not establish how much the liposomal delivery changes absorption, and the serving cost is high.</p>
85 Performance

Pharma GABA 250 mg

Natural Factors Stress-Relax
<p>250 mg fermented branded GABA provides a higher targeted amount than the original and may offer greater calming depth. The branded source improves ingredient definition, although oral GABA effects can vary and drowsiness remains possible.</p>
84 Performance

GABA 500 mg

NOW
<p>500 mg GABA with 2 mg vitamin B6 provides a higher targeted amount than the original and may offer greater calming depth. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
84 Budget

GABA

NOW
<p>Lower serving cost and 500 mg GABA make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
81 Budget

GABA 750 mg

Source Naturals Serene Science
<p>Lower serving cost and 750 mg GABA make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, while the high amount may increase drowsiness.</p>
83 Budget

GABA 500 mg

Nutricost
<p>Lower serving cost and 500 mg GABA with 2 mg vitamin B6 make this a more economical option for the same GABA-focused sleep and stress goals. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
83 Value

GABA 500 mg

NOW
<p>Lower serving cost paired with 500 mg GABA with 2 mg vitamin B6 creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
83 Value

GABA 500 mg

Swanson
<p>Lower serving cost paired with 500 mg GABA creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, and drowsiness remains possible.</p>
81 Value

GABA Powder

Source Naturals Serene Science
<p>Lower serving cost paired with 750 mg GABA creates a stronger balance of focused calming support and value than the original. Generic sourcing and uncertain oral brain availability limit confidence, while the high amount may increase drowsiness.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsStress Relief Mood Support forGABA
  2. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  3. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  4. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  5. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  6. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  7. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  8. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  9. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  10. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  11. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  12. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA