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Target-Mins Calcium Magnesium Potassium 500 mg : 500 mg : 99 mg

Country Life
4.6
★ ★ ★ ★ ★
(13085 ratings)
Phosphorus 250 mg
Calcium 500 mg
Magnesium 500 mg
Potassium 99 mg
Product Image
Score81
A concentrated calcium-magnesium blend with several useful forms and added phosphorus. High magnesium, included oxide, and missing vitamin cofactors limit everyday suitability.
How scoring works
Quantity:90 Tablet(s) • (45 servings)
Goals:
Bone Health
General Health
Energy
Cardiovascular Support
Stress Relief
Heart Health

Score 81

A concentrated calcium-magnesium blend with several useful forms and added phosphorus. High magnesium, included oxide, and missing vitamin cofactors limit everyday suitability.
How scoring works
$16.57($0.36 per serving)
iHerb
$ 19.49
Amazon
$ 16.57
Walmart
$ 20.46
Vitacost
$ 19.49
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Analysis

Calcium and magnesium are each supplied at 500 mg, supported by 250 mg phosphorus and a small potassium contribution. Citrate, taurinate, hydroxyapatite, and amino-acid-related forms give the blend more depth than an oxide-only product.

Magnesium oxide still weakens the absorption profile, and 500 mg of supplemental magnesium may be difficult to tolerate in one serving. The 99 mg potassium amount is nutritionally modest and does not make the formula a meaningful potassium supplement.

Two tablets deliver substantial mineral coverage for people with a defined intake gap. The product omits vitamin D and K, so it is less complete for bone support than formulas that pair minerals with those cofactors.

Who is it for
  • Adults needing substantial calcium and magnesium
  • People who prefer a multi-form tablet blend
Best for
  • Bone-mineral intake
  • Muscle and nerve support
  • Combined calcium-magnesium supplementation

Pros

  • Provides substantial calcium and magnesium
  • Includes citrate and taurinate forms
  • Adds hydroxyapatite-derived phosphorus
  • Fully discloses mineral amounts

Cons

  • Contains magnesium oxide
  • Potassium amount is very small
  • Does not include vitamin D or K
  • Large mineral dose may be hard to tolerate

Warnings

  • The 500 mg supplemental magnesium amount may cause diarrhea, cramping, or nausea.
  • People with kidney disease or a clinician-directed potassium, phosphorus, or calcium restriction should verify that the mineral load is appropriate.
  • Calcium and magnesium can reduce absorption of levothyroxine and tetracycline or quinolone antibiotics, so doses should be separated as directed.

Nutrient quality

82 Highest impact

Citrate, hydroxyapatite, taurate, and other named forms provide good mineral-form breadth and substantial core doses. Magnesium is high for a single serving, and the potassium amount adds limited practical depth.

Ingredient transparency

81 Highest impact

Every listed active has a stated amount, and no proprietary blend obscures the core formula. Daily-use directions and non-active ingredients are missing from the supplied details.

Customer satisfaction

70 High impact

The supplied average rating is strong and is supported by an exceptionally large review count. No detailed feedback is available to assess recurring concerns or purpose-specific experiences.

Value for money

89 Highest impact

Substantial mineral amounts and several useful forms provide good value. The modest potassium dose and included magnesium oxide are the main quality trade-offs.

Report analysis

Goals

Bone Health
Bone Health
Impact
Highest effect
A Goal FitA- Strength of SupportB CoverageB+ Formula Quality
Phosphorus · 250 mgMagnesium · 500 mgCalcium · 500 mg

Equal amounts of calcium and magnesium plus bone-like hydroxyapatite phosphorus provide strong structural mineral support. Several organic mineral forms improve the absorption profile.

The formula is well dosed for its main minerals but omits vitamin D and vitamin K cofactors. Magnesium oxide lowers consistency within an otherwise high-quality mineral blend.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Phosphorus Supportive 44 studies
Potassium Supportive 39 studies
General Health
General Health
Impact
High effect
A- Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Magnesium · 500 mg

The mineral blend supplies substantial magnesium and calcium alongside a smaller potassium amount. Several organic magnesium forms support absorption, but included magnesium oxide lowers the quality of the blend.

The combination addresses muscle, nerve, and structural needs more broadly than a single-mineral supplement. The magnesium amount is above the preferred range, so digestive tolerance may limit routine use for some people.

Study evidence
Magnesium Supportive 114 studies
Energy
Energy
Impact
High effect
A- Goal FitB- Strength of SupportC CoverageB- Formula Quality
Magnesium · 500 mgPotassium · 99 mg

Magnesium directly supports ATP-producing enzymes, while calcium and potassium contribute to muscle and nerve function. The disclosed mineral amounts are substantial.

Several organic magnesium forms are mixed with poorly absorbed magnesium oxide, and the 500 mg magnesium amount may cause digestive effects. The formula supports electrolyte and mineral status but does not cover alertness or stress-resilience pathways.

Study evidence
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitB Strength of SupportD+ CoverageC- Formula Quality
Potassium · 99 mgMagnesium · 500 mg

Magnesium supports heart rhythm, vascular relaxation, and blood-pressure regulation, while potassium adds a small electrolyte contribution. Multiple organic and chelated forms are included, but magnesium oxide lowers the expected absorption quality.

The formula is weighted toward calcium and bone minerals and does not address lipids, omega-3 status, arterial calcium handling, or antioxidant protection. The large supplemental magnesium amount may cause diarrhea or cramping, and people with impaired kidney function may not clear magnesium or potassium normally.

Study evidence
Magnesium Supportive 123 studies
Potassium Supportive 117 studies
Stress Relief
Stress Relief
Impact
High effect
B Goal FitB Strength of SupportD+ CoverageC- Formula Quality
Magnesium · 500 mg

Magnesium provides direct foundational support for nerve regulation and muscle relaxation, while the high disclosed amount may matter most when intake is inadequate. Citrate, taurate, aspartate, and other organic forms improve the blend, but included oxide lowers absorption quality.

Calcium, phosphorus, and the modest potassium amount broaden mineral support without adding a strong independent stress-relief pathway. The high supplemental magnesium amount may cause diarrhea or cramping, with greater concern for people whose kidneys cannot clear magnesium normally.

Study evidence
Magnesium Supportive 13 studies
Heart Health
Heart Health
Impact
High effect
C+ Goal FitB Strength of SupportC- CoverageC Formula Quality
Magnesium · 500 mg

Magnesium and potassium support vascular tone, normal heart rhythm, and blood-pressure regulation. The large calcium component makes the formula more bone focused and it lacks lipid, nitric-oxide, or cardiac-energy support.

The product name indicates substantial magnesium but modest potassium, while the label repeats totals across multiple forms and obscures each form’s contribution. High magnesium may cause diarrhea, and potassium requires caution with kidney disease or potassium-raising medicines.

Study evidence
Magnesium Supportive 158 studies
Potassium Supportive 182 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Alpha-Ketoglutarate, Calcium Aspartate, Calcium Citrate, Calcium Hydroxyapatite, Calcium Lysinate)
 500 mg
Phosphorus (Calcium Hydroxyapatite)
 250 mg
Magnesium (Magnesium Alpha-Ketoglutarate, Magnesium Aspartate, Magnesium Citrate, Magnesium Oxide, Magnesium Taurinate)
 500 mg
Potassium (Potassium Alpha-Ketoglutarate, Potassium Aspartate, Potassium Citrate)
 99 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
Phosphorus (Calcium Hydroxyapatite) · 250 mg OverallScore100
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Calcium hydroxyapatite supplies a bone-like phosphorus form at a targeted and clearly stated dose. Two tablets deliver the full serving without an excessive pill count. The per-serving cost compares very favorably with the collection benchmark.

View ingredientView products
Calcium (Calcium Alpha-Ketoglutarate, Calcium Aspartate, Calcium Citrate, Calcium Hydroxyapatite, Calcium Lysinate) · 500 mg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The calcium blend includes hydroxyapatite and citrate alongside several other named forms, supporting good absorption potential. A 500 mg serving is well aligned with efficient single-dose absorption, and the elemental amount is clear despite the blend details being condensed. The serving cost remains favorable, and no concerning additives are shown in the supplied data.

View ingredientView products
Magnesium (Magnesium Alpha-Ketoglutarate, Magnesium Aspartate, Magnesium Citrate, Magnesium Oxide, Magnesium Taurinate) · 500 mg OverallScore71
D Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value

The blend includes taurate, citrate, and aspartate but also magnesium oxide, creating mixed absorption potential. The elemental amount is clear but sits above the preferred therapeutic range, while the equal calcium amount avoids the stated competition concern. A below-median serving cost supports good value, although no patented material is identified.

View ingredientView products
Loading alternative details
86 Performance

Calcium & Magnesium Citrate Powder with Vitamin D3

NOW
<p>Balanced calcium and magnesium citrate with vitamin D3 provides a more coherent bone-support strategy than the original’s mixed forms and very high magnesium amount. Potassium and phosphorus are absent, but the core minerals use consistently useful forms.</p>
82 Performance

Calcium & Magnesium Mineral Complex

Nature's Way
<p>Calcium citrate and malate plus magnesium bisglycinate and citrate improve average form quality compared with the original’s inclusion of magnesium oxide. Carbonate and oxide still appear, but the more moderate amounts may be easier to tolerate.</p>
80 Performance

Bone Builder Forte

Metagenics
<p>Microcrystalline hydroxyapatite and vitamin D3 offer focused calcium-phosphorus support with clear, practical amounts. Magnesium and potassium are absent and serving cost is higher, but the bone-specific design is more precise than the original’s oversized mineral combination.</p>
85 Budget

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a balanced mineral combination at a much lower serving cost than the original. The formula omits potassium and phosphorus, but its focused design and favorable forms suit routine calcium-magnesium support.</p>
88 Budget

Calcium Hydroxyapatite Caps

NOW
<p>Hydroxyapatite supplies calcium with naturally paired phosphorus in a simple capsule at lower daily cost. It does not provide the original’s substantial magnesium or modest potassium, but bone-mineral form quality and dose clarity are strong.</p>
80 Budget

Calcium Mag & D Complex

Nature's Way
<p>Citrate, malate, and aspartate improve the calcium-magnesium mix while keeping daily cost below the original. Carbonate and oxide remain in the blend and the vitamin D amount is small, but the mineral serving is less aggressive.</p>
85 Value

Cal/Mag Caps

NaturesPlus
<p>Chelated calcium and magnesium provide balanced amounts and strong form quality at a lower serving cost than the original. The formula omits phosphorus and potassium, yet its simpler design offers a cleaner quality-to-cost trade-off.</p>
80 Value

Liquid Calcium Magnesium Citrate with Vitamin D3 Natural Strawberry Flavor

Solgar
<p>Calcium and magnesium citrate with vitamin D3 create a coherent liquid option at roughly comparable daily value. Duplicate vitamin D entries and carbohydrate labeling reduce clarity, but the core forms are more consistent than the original’s mixed magnesium blend.</p>
80 Value

Target-Mins Calcium Magnesium Complex

Country Life
<p>Substantial calcium, magnesium, and phosphorus provide a close bone-mineral match at a lower serving cost. Magnesium oxide and missing vitamin D remain weaknesses, but the formula removes the original’s lightly dosed potassium and improves practical value.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association between phosphorus intake and bone health in the NHANES population.
    Lee AW; Cho SS · Nutrition journal · 2016
    Cross-sectional studyBone Health forPhosphorus
  2. Dairy product consumption, eating habits, sedentary behaviour and physical activity association with bone mineral density among adolescent boys: a cross-sectional observational study.
    Kopiczko A; Czapla M; Juárez-Vela R; Ross C; Uchmanowicz B · BMC pediatrics · 2024
    Cross-sectional study115 participantsBone Health forPhosphorus
  3. Association between serum phosphorus levels and pelvic bone mineral density in U.S. adults aged 18-59 years.
    Jiang T; Pan Y; Xu J; Ge J; Ji S; Li T; Zhang Y · BMC musculoskeletal disorders · 2025
    Cross-sectional study5,589 participantsBone Health forPhosphorus
  4. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forPhosphorus
  5. Management of Hyperphosphatemia in End-Stage Renal Disease: A New Paradigm.
    Rastogi A; Bhatt N; Rossetti S; Beto J · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2021
    Systematic reviewBone Health forPhosphorus
  6. Phosphate Metabolism in Health and Disease.
    Peacock M · Calcified tissue international · 2021
    Narrative reviewBone Health forPhosphorus
  7. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  8. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  9. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  10. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  11. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  12. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  13. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  14. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  15. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  16. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  17. Burosumab Improved Histomorphometric Measures of Osteomalacia in Adults with X-Linked Hypophosphatemia: A Phase 3, Single-Arm, International Trial.
    Insogna KL; Rauch F; Kamenický P; Ito N; Kubota T; Nakamura A; Zhang L; Mealiffe M; San Martin J; Portale AA · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Single-arm trial14 participantsBone Health forPhosphorus
  18. Early high calcium and phosphorus intake by parenteral nutrition prevents short-term bone strength decline in preterm infants.
    Pereira-da-Silva L; Costa A; Pereira L; Filipe A; Virella D; Leal E; Moreira A; Rosa M; Mendes L; Serelha M · Journal of pediatric gastroenterology and nutrition · 2011
    Randomized trialBone Health forPhosphorus
  19. Expert consensus on clinical management of metabolic bone disease of prematurity (2021).
    Yan-Mei C; Xin-Zhu L; Rong Z; Xi-Hong L; Xiao-Mei T; Ping-Yang C; Zhi-Chun F; Nutritional Committee of Neonatology Branch of Chinese Medical Doctor Association; Neonatal Nutrition and Health Management Group, Professional Committee of Child Health, Chinese Medical Doctor Association; Editorial Committee of Chinese Journal of Contemporary Pediatrics. · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Guideline / consensusBone Health forPhosphorus
  20. Effect of potassium citrate on bone density, microarchitecture, and fracture risk in healthy older adults without osteoporosis: a randomized controlled trial.
    Jehle S; Hulter HN; Krapf R · The Journal of clinical endocrinology and metabolism · 2013
    Randomized trial201 participantsBone Health forPotassium
  21. Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women.
    Frassetto L; Morris RC; Sebastian A · The Journal of clinical endocrinology and metabolism · 2005
    Randomized trial170 participantsBone Health forPotassium
  22. Partial neutralization of the acidogenic Western diet with potassium citrate increases bone mass in postmenopausal women with osteopenia.
    Jehle S; Zanetti A; Muser J; Hulter HN; Krapf R · Journal of the American Society of Nephrology : JASN · 2007
    Randomized trial161 participantsBone Health forPotassium
  23. Potassium citrate supplementation results in sustained improvement in calcium balance in older men and women.
    Moseley KF; Weaver CM; Appel L; Sebastian A; Sellmeyer DE · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013
    Randomized trial52 participantsBone Health forPotassium
  24. Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
    He FJ; Marciniak M; Carney C; Markandu ND; Anand V; Fraser WD; Dalton RN; Kaski JC; MacGregor GA · Hypertension (Dallas, Tex. : 1979) · 2010
    Randomized trial42 participantsBone Health forPotassium
  25. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  26. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  27. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  28. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  29. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  30. Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies.
    Gan L; Zhao B; Inoue-Choi M; Liao LM; Graubard BI; Weinstein SJ; Albanes D; Huang J · BMC medicine · 2024
    Meta-analysis416,104 participantsCardiovascular Support forPotassium
  31. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledCardiovascular Support Heart Health forPotassium
  32. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials.
    Geleijnse JM; Kok FJ; Grobbee DE · Journal of human hypertension · 2003
    Meta-analysis27 studies pooledCardiovascular Support forPotassium
  33. Twenty-Four-Hour Urinary Sodium and Potassium Excretion and Their Associations With Blood Pressure Among Adults in China: Baseline Survey of Action on Salt China.
    Li Y; Zhang P; Wu J; Ma J; Xu J; Zhang X; Luo R; Liu M; Sun Y; Li X; Tan M; He FJ; MacGregor GA; Li X · Hypertension (Dallas, Tex. : 1979) · 2021
    Cross-sectional study5,353 participantsCardiovascular Support forPotassium
  34. Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program.
    Wang DD; Li Y; Nguyen XT; Song RJ; Ho YL; Hu FB; Willett WC; Wilson PWF; Cho K; Gaziano JM; Djoussé L; On Behalf Of The Va Million Veteran Program · Nutrients · 2022
    Cohort study180,156 participantsCardiovascular Support forPotassium
  35. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  36. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  37. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  38. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  39. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  40. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  41. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  42. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  43. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  44. [Efficacy of potassium N-acetylaminosuccinate (Cogitum) in the treatment of asthenic syndrome: results of double-blind placebo-controlled trial].
    Esin RG; Khayrullin IK; Esin OR; Fatykhova AF; Gismatullina EI; Isaeva YN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2023
    Randomized trial37 participantsEnergy forPotassium
  45. Human resting energy expenditure in relation to dietary potassium.
    Dériaz O; Thériault G; Lavallée N; Fournier G; Nadeau A; Bouchard C · The American journal of clinical nutrition · 1991
    Randomized trial8 participantsEnergy forPotassium
  46. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  47. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  48. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  49. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  50. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  51. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  52. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  53. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  54. Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
    Poorolajal J; Zeraati F; Soltanian AR; Sheikh V; Hooshmand E; Maleki A · PloS one · 2017
    Meta-analysis1,213 participants23 studies pooledHeart Health forPotassium
  55. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study.
    O'Donnell M; Mente A; Rangarajan S; McQueen MJ; O'Leary N; Yin L; Liu X; Swaminathan S; Khatib R; Rosengren A; Ferguson J; Smyth A; Lopez-Jaramillo P; Diaz R; Avezum A; Lanas F; Ismail N; Yusoff K; Dans A; Iqbal R; Szuba A; Mohammadifard N; Oguz A; Yusufali AH; Alhabib KF; Kruger IM; Yusuf R; Chifamba J; Yeates K; Dagenais G; Wielgosz A; Lear SA; Teo K; Yusuf S; PURE Investigators · BMJ (Clinical research ed.) · 2019
    Cohort study103,570 participantsHeart Health forPotassium
  56. Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies.
    D'Elia L; Cappuccio FP; Masulli M; La Fata E; Rendina D; Galletti F · Nutrients · 2023
    Meta-analysis332 participants5 studies pooledHeart Health forPotassium
  57. Effects of potassium supplementation on office, home, and 24-h blood pressure in patients with essential hypertension.
    Kawano Y; Minami J; Takishita S; Omae T · American journal of hypertension · 1999
    Randomized trial55 participantsHeart Health forPotassium
  58. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  59. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  60. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  61. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  62. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  63. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  64. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  65. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  66. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  67. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium