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RxOmega-3

Natural Factors
4.7
★ ★ ★ ★ ★
(14613 ratings)
DHA 200 mg
Fish Oil 1170 mg
Omega-3 630 mg
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Score80
A useful daily omega-3 amount and named small-fish sources are positives, but ethyl ester delivery and ambiguous fatty-acid labeling limit confidence.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Cardiovascular Support
Anti-Inflammatory Support
Skin Health

Score 80

A useful daily omega-3 amount and named small-fish sources are positives, but ethyl ester delivery and ambiguous fatty-acid labeling limit confidence.
How scoring works
$18.17($0.30 per serving)
Vitacost
$ 18.17
iHerb
$ 18.17
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Analysis

The daily softgel provides 630 mg of total omega-3 from 1,170 mg of fish-oil concentrate. Named anchovy, mackerel, and sardine sources add useful sourcing detail, while the listed pharmaceutical-grade description offers some quality context.

The active listing is the main limitation. Two ethyl ester entries are both called DHA, so a distinct EPA amount is not available, and ethyl esters are generally less efficiently absorbed than triglyceride forms.

The formula fits routine cardiovascular, inflammatory-balance, or skin-barrier support better than high-potency targeted use. No antioxidant protection or independent purity verification is included in the supplied details, leaving oxidation and contaminant control uncertain.

Who is it for
  • Adults seeking moderate daily marine omega-3 support
  • People who prefer a one-softgel serving
  • Value-focused shoppers who accept an ethyl ester oil
Best for
  • Everyday cardiovascular support
  • Inflammatory-balance support
  • Skin-barrier lipid support

Pros

  • Provides 630 mg total omega-3 per serving
  • Names anchovy, mackerel, and sardine sources
  • Concentrates active omega-3 within the fish oil

Cons

  • Lists two DHA entries without a distinct EPA amount
  • Uses the less readily absorbed ethyl ester form
  • Does not state antioxidant or independent purity testing

Warnings

  • Avoid if allergic to fish because the oil comes from anchovy, mackerel, and sardine
  • Fish oil may add to bleeding risk with anticoagulant or antiplatelet medicines

Nutrient quality

87 Highest impact

The concentrated oil supplies a useful active amount from named small-fish sources. Ethyl-ester delivery and an unclear EPA-to-DHA split limit quality.

Ingredient transparency

71 High impact

Important active-label details are incomplete or ambiguous. Complete use directions and inactive-ingredient details are not available.

Customer satisfaction

72 High impact

The aggregate satisfaction measure is favorable, with response volume determining how much confidence it deserves. Comment-level evidence is absent, so recurring complaints and purpose fit cannot be verified.

Value for money

90 Highest impact

A substantial active amount and modest serving cost create strong value. The basic ethyl-ester form and ambiguous fatty-acid split keep it from leading the category.

Report analysis

Goals

Cardiovascular Support
Impact
High effect
A Goal FitC+ Strength of SupportC+ CoverageA- Formula Quality
Fish Oil · 1170 mg

Marine omega-3 fatty acids directly support lipid management and endothelial health, giving the formula strong cardiovascular relevance. The disclosed 630 mg total is a moderate daily amount rather than a concentrated therapeutic serving.

The label lists two DHA entries but no distinct EPA amount, making the active balance unclear. Ethyl ester delivery is less efficiently absorbed than triglyceride oil, and independent oxidation testing is not disclosed.

Study evidence
Fish Oil Supportive 185 studies
Anti-Inflammatory Support
Impact
High effect
A- Goal FitC Strength of SupportD- CoverageA- Formula Quality
Fish Oil · 1170 mg

The concentrated fish oil provides a meaningful disclosed omega-3 amount from named small fish. Omega-3 fatty acids support the production of compounds that help resolve inflammatory signaling.

Two entries are both labeled as DHA and no separate EPA amount is shown, so the active balance is unclear. The ethyl ester form may absorb less efficiently than triglyceride forms, and no independent testing or antioxidant protection is stated.

Study evidence
Fish Oil Supportive 68 studies
Skin Health
Impact
High effect
B- Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Omega-3 · 630 mg

630 mg of total omega-3 may support the skin lipid barrier and a balanced inflammatory response. Evidence is relevant to barrier function, but the formula does not address collagen structure or direct hydration-binding ingredients.

The ethyl ester form offers moderate absorption and small-fish sources are named, but EPA and DHA are not clearly separated. Missing antioxidant protection and independent purity evidence reduce quality confidence.

Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Polyunsaturated Fat
1 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate
1170 mg
Omega-3 Fatty Acids
630 mg
Docosahexaenoic Acid Ethyl Ester
200 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 200 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

The two disclosed DHA entries together provide a high serving amount from named small-fish sources. The ethyl ester form is less readily absorbed than triglyceride forms, and no protective antioxidant is listed. The smaller package combines strong active-ingredient value with pharmaceutical-grade purity disclosure.

Fish Oil · 1170 mg OverallScore52
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB+ Value

The pharmaceutical-grade oil comes from named small fish, but its ethyl ester form is less efficiently absorbed than triglyceride oil. The supplied data show two DHA entries and no distinct EPA amount, making the active profile unclear despite a moderate combined quantity. Cost efficiency appears favorable using the disclosed fatty-acid amounts, while independent testing and oxidation protection are not stated.

Omega-3 · 630 mg OverallScore48
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The named ethyl ester form offers moderate absorption potential rather than the preferred triglyceride forms. Small-fish sources are disclosed, but antioxidant protection and independent purity verification are not stated. The active concentration falls just below the collection's middle potency band, although the cost per active amount is favorable.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  2. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  3. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  4. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  5. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  6. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  7. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  8. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  9. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  10. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3