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RxOmega-3

Natural Factors
4.7
★ ★ ★ ★ ★
(14616 ratings)
DHA 200 mg
Fish Oil 1170 mg
Omega-3 630 mg
Product Image
Score82
A large, economical supply of moderate-strength omega-3 is useful for daily maintenance, but the active labeling is unclear and the oil uses an ethyl ester form.
How scoring works
Quantity:240 Softgel(s) • (240 servings)
Goals:
Cardiovascular Support
Skin Health
Anti-Inflammatory Support

Score 82

A large, economical supply of moderate-strength omega-3 is useful for daily maintenance, but the active labeling is unclear and the oil uses an ethyl ester form.
How scoring works

Also available as

2 options
120 servings Omega-3 630 mg, Fish Oil 1170 mg +1 more • 120 Softgel(s) • 120 servings $26.57 ($0.22 per serving) 60 servings Omega-3 630 mg, Fish Oil 1170 mg +1 more • 60 Softgel(s) • 60 servings $18.17 ($0.30 per serving)
$44.77($0.18 per serving)
Pure Formulas
$ 44.77
iHerb
$ 44.77
Vitacost
$ 44.77
Report prices

Analysis

One softgel supplies 630 mg total omega-3 from 1,170 mg of fish-oil concentrate. The large bottle reduces replacement frequency and makes sense for people who take omega-3 consistently.

Anchovy, mackerel, and sardine sources are identified, but the active breakdown is not dependable. Both fatty-acid entries are labeled DHA ethyl ester, leaving EPA undisclosed and using a form with moderate rather than preferred absorption.

The amount can support routine cardiovascular, skin-barrier, and inflammatory-balance goals. Lack of a stated antioxidant and independent purity or oxidation testing leaves important quality questions open.

Who is it for
  • Long-term daily omega-3 users
  • Households wanting a high-count bottle
  • Adults seeking maintenance-level support
Best for
  • Routine cardiovascular support
  • Skin-barrier support
  • General inflammatory balance

Pros

  • Provides 630 mg total omega-3 per serving
  • Uses named small-fish sources
  • High-count bottle supports consistent use

Cons

  • Repeats DHA without clearly listing EPA
  • Uses ethyl ester fatty acids
  • No stated antioxidant or independent testing

Warnings

  • Avoid if allergic to anchovy, herring-family fish, mackerel, or sardine
  • Fish oil may compound the effects of anticoagulant or antiplatelet medicines

Nutrient quality

87 Highest impact

The concentrated oil supplies a useful active amount from named small-fish sources. Ethyl-ester delivery and an unclear EPA-to-DHA split limit quality.

Ingredient transparency

71 High impact

Important active-label details are incomplete or ambiguous. Complete use directions and inactive-ingredient details are not available.

Customer satisfaction

72 High impact

The aggregate satisfaction measure is favorable, with response volume determining how much confidence it deserves. Comment-level evidence is absent, so recurring complaints and purpose fit cannot be verified.

Value for money

99 Highest impact

Bulk packaging and a substantial active amount create exceptional serving value. The basic ethyl-ester form and ambiguous fatty-acid split are the main quality limits.

Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
High effect
A Goal FitC Strength of SupportC+ CoverageB+ Formula Quality
Fish Oil · 1170 mg

The disclosed omega-3 amount supports lipid and inflammatory balance, and the named small-fish sources are appropriate for cardiovascular use. The amount is modest for targeted triglyceride reduction, while the missing EPA figure makes the fatty-acid balance difficult to assess.

The ethyl-ester form is less efficiently absorbed than triglyceride forms and no independent purity or oxidation testing is provided. Enteric softgel delivery may reduce aftertaste, but the two DHA entries create a label-clarity concern.

Study evidence
Fish Oil Supportive 185 studies
Skin Health
Skin Health
Impact
High effect
B+ Goal FitC Strength of SupportC CoverageA Formula Quality
Omega-3 · 630 mg

Omega-3 fatty acids may support the skin barrier and help regulate inflammatory signaling. The disclosed 630 mg total omega-3 amount provides useful support, but EPA and DHA details are incomplete.

The softgel format suits fatty-acid delivery. Missing molecular form, separate fatty-acid amounts, oxidation control, and independent purity testing limit quality confidence.

Study evidence
Omega-3 Supportive 35 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B Goal FitC Strength of SupportD+ CoverageB Formula Quality
Fish Oil · 1170 mg

Fish-oil fatty acids provide meaningful support for inflammation-related signaling. The label appears to list DHA twice without a distinct EPA amount, limiting confidence in the active balance.

Named small-fish sources improve source transparency, but the ethyl ester form is less efficiently absorbed than triglyceride oil. Fish oil may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines.

Study evidence
Fish Oil Supportive 68 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Polyunsaturated Fat
1 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate
1170 mg
Omega-3 Fatty Acids
630 mg
Docosahexaenoic Acid Ethyl Ester
200 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 200 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

The two disclosed DHA entries together provide a high serving amount from named small-fish sources. The ethyl ester form is less readily absorbed than triglyceride forms, and no protective antioxidant is listed. The high-count package combines strong active-ingredient value with pharmaceutical-grade purity disclosure.

View ingredientView products
Fish Oil · 1170 mg OverallScore56
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The pharmaceutical-grade oil uses named small fish but remains in the less efficiently absorbed ethyl ester form. Its two DHA entries lack a distinct EPA amount, leaving the fatty-acid balance unclear. The large package offers favorable cost efficiency based on disclosed actives, while independent testing and antioxidant protection are not stated.

View ingredientView products
Omega-3 · 630 mg OverallScore48
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The ethyl ester form has moderate absorption potential and comes from named small fish. Label clarity is limited because separate EPA and DHA amounts are not presented reliably, while antioxidant and independent purity details are missing. The large package delivers the disclosed active amount at a particularly low ongoing cost.

View ingredientView products
Loading alternative details
85 Performance

Omega-3 Triglyceride Fish Oil 1100 mg

NATURELO Premium Supplements
Triglyceride fish oil delivers a highly concentrated EPA-led omega-3 serving with clear fatty-acid amounts and favorable value. Molecular distillation adds some purity assurance, while missing independent testing, fish species, and antioxidant protection leave smaller quality gaps. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
83 Performance

Ultra Strength One-per-Day RxOmega-3 with Vitamin D3 25 mcg (1000IU)

Natural Factors
A concentrated omega-fatty-acid amount and useful vitamin D3 addition provide strong one-softgel value. Ethyl-ester delivery is less absorbable than triglyceride oil, while duplicated DHA lines leave the EPA amount unclear. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
86 Performance

Purified & Clear Omega 3 Fish Oil 1000 mg

Doctor's Best
A substantial, clearly separated EPA and DHA serving offers strong potency and active value. The ethyl-ester form is less readily absorbed than triglyceride oil, and oxidation protection plus independent purity testing are not supplied. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
69 Budget

Kid's Chewable DHA 100 mg Bursting Orange Flavor!

Carlson
Triglyceride fish oil and vitamin E suit a child-friendly chewable, but the active omega-3 amount and oil concentration are low. A long supply and extensive rating volume help usability, while missing purity testing and malformed label entries reduce clarity. Compared with the original, its lower serving cost improves affordability while retaining Omega-3 and DHA and Fish Oil support.
86 Budget

Omega-3 Triglyceride Fish Oil 1100 mg

NATURELO Premium Supplements
No genuinely cheaper eligible option remains for this required slot. Triglyceride fish oil delivers a highly concentrated EPA-led omega-3 serving with clear fatty-acid amounts and especially favorable package value. The formula keeps Omega-3 and DHA and Fish Oil in scope but should be viewed as a close eligible substitute rather than a lower-cost option.
82 Budget

Ultra Strength One-per-Day RxOmega-3

Natural Factors
No genuinely cheaper eligible option remains for this required slot. A concentrated omega-fatty-acid amount and large supply create strong one-softgel value. The formula keeps Omega-3 and DHA and Fish Oil in scope but should be viewed as a close eligible substitute rather than a lower-cost option.
80 Value

Ultra Strength One-per-Day RxOmega-3

Natural Factors
A concentrated omega-fatty-acid amount provides convenient one-softgel support with good active value. Ethyl-ester delivery and duplicated DHA lines reduce absorption quality and label clarity. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
84 Value

Omega 3 Platinum + D 2000 mg

Advanced Nutrition by Zahler
Triglyceride-form oil, clearly separated EPA and DHA, and a meaningful vitamin D3 amount create a coherent formula. Moderate oil concentration plus missing source, oxidation, and independent purity details remain the main limitations. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
84 Value

Fish Oil 1400 mg

Nature's Bounty
A meaningful EPA-led amount and strong oil concentration provide good active value. The ethyl-ester form is less readily absorbed, while fish source, antioxidant protection, and independent purity testing are not stated. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  2. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  3. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  4. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  5. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  6. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  7. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  8. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  9. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  10. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3