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RxOmega-3

Natural Factors
4.7
★ ★ ★ ★ ★
(14614 ratings)
DHA 200 mg
Fish Oil 1170 mg
Omega-3 630 mg
Product Image
Score81
The larger package offers practical value for a moderate omega-3 dose, but the duplicated DHA listing and ethyl ester form are meaningful drawbacks.
How scoring works
Quantity:120 Softgel(s) • (120 servings)
Goals:
Cardiovascular Support
Anti-Inflammatory Support
Skin Health

Score 81

The larger package offers practical value for a moderate omega-3 dose, but the duplicated DHA listing and ethyl ester form are meaningful drawbacks.
How scoring works

Also available as

2 options
240 servings Omega-3 630 mg, Fish Oil 1170 mg +1 more • 240 Softgel(s) • 240 servings $44.77 ($0.18 per serving) 60 servings Omega-3 630 mg, Fish Oil 1170 mg +1 more • 60 Softgel(s) • 60 servings $18.17 ($0.30 per serving)
$26.57($0.22 per serving)
Vitacost
$ 26.57
iHerb
$ 26.57
Report prices

Analysis

Each softgel supplies 630 mg of total omega-3 from 1,170 mg of concentrated fish oil. Anchovy, mackerel, and sardine are named, and the larger bottle suits people planning consistent daily use.

Two entries are both identified as DHA ethyl ester, with no clear separate EPA amount. That labeling issue prevents a confident assessment of fatty-acid balance, while the ethyl ester form is not as readily absorbed as preferred triglyceride forms.

The dose is practical for general cardiovascular, inflammatory-balance, and skin support, though it is not especially high for focused use. Antioxidant protection and independent purity testing are not stated in the supplied information.

Who is it for
  • Regular omega-3 users who want a larger bottle
  • Adults seeking maintenance-level marine fats
  • Shoppers comfortable with an ethyl ester formula
Best for
  • Long-term daily use
  • Basic cardiovascular support
  • General inflammatory balance

Pros

  • Delivers 630 mg total omega-3 per softgel
  • Uses named small-fish sources
  • Larger package improves practical value

Cons

  • Does not clearly disclose a separate EPA amount
  • Uses an ethyl ester oil
  • Omits stated antioxidant and independent testing details

Warnings

  • Not suitable for people with an allergy to the named fish sources
  • Fish oil can increase bleeding tendency when combined with blood-thinning medicines

Nutrient quality

87 Highest impact

The concentrated oil supplies a useful active amount from named small-fish sources. Ethyl-ester delivery and an unclear EPA-to-DHA split limit quality.

Ingredient transparency

71 High impact

Important active-label details are incomplete or ambiguous. Complete use directions and inactive-ingredient details are not available.

Customer satisfaction

72 High impact

The aggregate satisfaction measure is favorable, with response volume determining how much confidence it deserves. Comment-level evidence is absent, so recurring complaints and purpose fit cannot be verified.

Value for money

95 Highest impact

The large supply and substantial active amount create excellent value. The basic ethyl-ester form and ambiguous fatty-acid split are the main trade-offs.

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Goals

Cardiovascular Support
Cardiovascular Support
Impact
High effect
A Goal FitC+ Strength of SupportC+ CoverageA- Formula Quality
Fish Oil · 1170 mg

Marine omega-3 fatty acids directly support lipid management and endothelial health, giving the formula strong cardiovascular relevance. The disclosed 630 mg total is a moderate daily amount rather than a concentrated therapeutic serving.

The label lists two DHA entries but no distinct EPA amount, making the active balance unclear. Ethyl ester delivery is less efficiently absorbed than triglyceride oil, and independent oxidation testing is not disclosed.

Study evidence
Fish Oil Supportive 185 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
A- Goal FitC Strength of SupportD- CoverageA- Formula Quality
Fish Oil · 1170 mg

The concentrated fish oil provides a meaningful disclosed omega-3 amount from named small fish. Omega-3 fatty acids support the production of compounds that help resolve inflammatory signaling.

Two entries are both labeled as DHA and no separate EPA amount is shown, so the active balance is unclear. The ethyl ester form may absorb less efficiently than triglyceride forms, and no independent testing or antioxidant protection is stated.

Study evidence
Fish Oil Supportive 68 studies
Skin Health
Skin Health
Impact
High effect
B- Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Omega-3 · 630 mg

630 mg of total omega-3 may support the skin lipid barrier and a balanced inflammatory response. Evidence is relevant to barrier function, but the formula does not address collagen structure or direct hydration-binding ingredients.

The ethyl ester form offers moderate absorption and small-fish sources are named, but EPA and DHA are not clearly separated. Missing antioxidant protection and independent purity evidence reduce quality confidence.

Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Polyunsaturated Fat
1 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate
1170 mg
Omega-3 Fatty Acids
630 mg
Docosahexaenoic Acid Ethyl Ester
200 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 200 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

The two disclosed DHA entries together provide a high serving amount from named small-fish sources. The ethyl ester form is less readily absorbed than triglyceride forms, and no protective antioxidant is listed. The larger package combines strong active-ingredient value with pharmaceutical-grade purity disclosure.

View ingredientView products
Fish Oil · 1170 mg OverallScore56
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The pharmaceutical-grade oil uses named small-fish sources, though the ethyl ester form is less efficiently absorbed than triglyceride oil. Two DHA entries are shown without a distinct EPA amount, so the active balance is not transparent. The larger package delivers favorable active-fatty-acid value, but independent testing and oxidation protection are not stated.

View ingredientView products
Omega-3 · 630 mg OverallScore48
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The disclosed ethyl ester form provides moderate absorption potential, while the small-fish sources add useful sourcing detail. Separate EPA and DHA amounts remain unclear, and neither antioxidant protection nor independent purity verification is stated. A low cost per active amount supports good value despite the modest concentration.

View ingredientView products
Loading alternative details
86 Performance

Omega-3 Triglyceride Fish Oil 1100 mg

NATURELO Premium Supplements
Triglyceride fish oil delivers a highly concentrated EPA-led omega-3 serving with clear fatty-acid amounts and especially favorable package value. Molecular distillation adds some purity assurance, while missing independent testing, fish species, and antioxidant protection leave smaller quality gaps. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
82 Performance

Ultra Strength One-per-Day RxOmega-3

Natural Factors
A concentrated omega-fatty-acid amount and large supply create strong one-softgel value. Ethyl-ester delivery remains less absorbable than triglyceride oil, and duplicated DHA lines obscure the EPA amount. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
86 Performance

Purified & Clear Omega 3 Fish Oil 1000 mg

Doctor's Best
A substantial, clearly separated EPA and DHA serving offers strong potency and active value. The ethyl-ester form is less readily absorbed than triglyceride oil, and oxidation protection plus independent purity testing are not supplied. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and stronger formulation depth make it a better quality-focused match.
82 Budget

RxOmega-3

Natural Factors
A substantial omega-fatty-acid amount from named small fish and a bulk supply create exceptional recurring value. Ethyl-ester delivery and duplicated DHA lines still limit absorption and label clarity. Compared with the original, its lower serving cost improves affordability while retaining Omega-3 and DHA and Fish Oil support.
84 Budget

Omega 3 Fish Oil Concentrate

Solgar
The triglyceride form supports absorption and the individual fatty acids are clearly disclosed. Active concentration is modest, but low serving cost creates attractive value despite missing source, oxidation, and purity details. Compared with the original, its lower serving cost improves affordability while retaining Omega-3 and DHA and Fish Oil support.
69 Budget

Kid's Chewable DHA 100 mg Bursting Orange Flavor!

Carlson
Triglyceride fish oil and vitamin E suit a child-friendly chewable, but the active omega-3 amount and oil concentration are low. A long supply and extensive rating volume help usability, while missing purity testing and malformed label entries reduce clarity. Compared with the original, its lower serving cost improves affordability while retaining Omega-3 and DHA and Fish Oil support.
85 Value

Omega-3 Triglyceride Fish Oil 1100 mg

NATURELO Premium Supplements
Triglyceride fish oil delivers a highly concentrated EPA-led omega-3 serving with clear fatty-acid amounts and favorable value. Molecular distillation adds some purity assurance, while missing independent testing, fish species, and antioxidant protection leave smaller quality gaps. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
83 Value

Ultra Strength One-per-Day RxOmega-3 with Vitamin D3 25 mcg (1000IU)

Natural Factors
A concentrated omega-fatty-acid amount and useful vitamin D3 addition provide strong one-softgel value. Ethyl-ester delivery is less absorbable than triglyceride oil, while duplicated DHA lines leave the EPA amount unclear. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
84 Value

Omega 3 Platinum + D 2000 mg

Advanced Nutrition by Zahler
Triglyceride-form oil, clearly separated EPA and DHA, and a meaningful vitamin D3 amount create a coherent formula. Moderate oil concentration plus missing source, oxidation, and independent purity details remain the main limitations. Compared with the original, its Omega-3 and DHA and Fish Oil coverage and balance of formula depth and serving cost provide better practical value.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  2. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  3. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  4. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  5. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  6. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  7. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  8. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  9. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  10. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3