Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
Randomized trial201 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
Randomized trial60 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
Randomized trial77 participantsflagAnti-Inflammatory Support forscienceFish Oil
- The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
Randomized trial174 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
Meta-analysis49 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
Zhou A; Hyppönen E · International journal of epidemiology · 2023
Observational study294,970 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
Cross-sectional study9,809 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
Cohort study3,072 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
Meta-analysis127,477 participants13 studies pooledflagCardiovascular Support forscienceFish Oil
- Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
Randomized trial309 participantsflagCardiovascular Support forscienceFish Oil
- A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
Meta-analysis1,524 participants17 studies pooledflagCardiovascular Support forscienceFish Oil
- Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
Randomized trial422 participantsflagCardiovascular Support forscienceFish Oil
- Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
Meta-analysis6 studies pooledflagCardiovascular Support forscienceFish Oil
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceVitamin D
- A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
Randomized trial120 participantsflagCardiovascular Support forscienceVitamin D
- Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
Randomized trial224 participantsflagCardiovascular Support forscienceVitamin D
- Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
Randomized trial70 participantsflagCardiovascular Support forscienceVitamin D
- Paricalcitol and endothelial function in chronic kidney disease trial.
Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
Randomized trial88 participantsflagCardiovascular Support flagHeart Health forscienceVitamin D
- Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Saito Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Japan EPA lipid intervention study (JELIS) Investigators · Lancet (London, England) · 2007
Randomized trial18,645 participantsflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).
Saito Y; Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; JELIS Investigators, Japan · Atherosclerosis · 2008
Randomized trial14,981 participantsflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis.
Dinu M; Sofi F; Lotti S; Colombini B; Mattioli AV; Catapano AL; Casula M; Baragetti A; Wong ND; Steg PG; Ambrosio G · European journal of preventive cardiology · 2024
Meta-analysis134,144 participants18 studies pooledflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.
Matsuzaki M; Yokoyama M; Saito Y; Origasa H; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Matsuzawa Y; JELIS Investigators · Circulation journal : official journal of the Japanese Circulation Society · 2009
Randomized trialflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association.
Skulas-Ray AC; Wilson PWF; Harris WS; Brinton EA; Kris-Etherton PM; Richter CK; Jacobson TA; Engler MB; Miller M; Robinson JG; Blum CB; Rodriguez-Leyva D; de Ferranti SD; Welty FK; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology · Circulation · 2020
OtherflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
Randomized trial1,537 participantsflagHeart Health forscienceVitamin D
- Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
Meta-analysis81 studies pooledflagHeart Health forscienceVitamin D
- Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
Meta-analysis45 studies pooledflagHeart Health forscienceVitamin D
- Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
Randomized trial43 participantsflagJoint Health forscienceOmega-3
- Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
Randomized trial235 participantsflagJoint Health forscienceOmega-3
- Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
Meta-analysis1,018 participants18 studies pooledflagJoint Health forscienceOmega-3
- Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
Meta-analysis1,420 participants30 studies pooledflagJoint Health forscienceOmega-3
- A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
Goldberg RJ; Katz J · Pain · 2007
Meta-analysis17 studies pooledflagJoint Health forscienceOmega-3
- Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
Randomized trial413 participantsflagJoint Health forscienceVitamin D
- Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
Meta-analysis146,054 participants10 studies pooledflagJoint Health forscienceVitamin D
- Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
Meta-analysis1,599 participants6 studies pooledflagJoint Health forscienceVitamin D
- Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
Randomized trial413 participantsflagJoint Health forscienceVitamin D
- The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
Meta-analysis11,890 participants28 studies pooledflagJoint Health forscienceVitamin D
- The influence of n-3 polyunsaturated fatty acids on cognitive function in individuals without dementia: a systematic review and dose-response meta-analysis.
Suh SW; Lim E; Burm SY; Lee H; Bae JB; Han JW; Kim KW · BMC medicine · 2024
Meta-analysis9,660 participants24 studies pooledflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- EPA supplementation improves teacher-rated behaviour and oppositional symptoms in children with ADHD.
Gustafsson PA; Birberg-Thornberg U; Duchén K; Landgren M; Malmberg K; Pelling H; Strandvik B; Karlsson T · Acta paediatrica (Oslo, Norway : 1992) · 2011
Randomized trial92 participantsflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)-Should They Be Mandatory Supplements in Pregnancy?
Amza M; Haj Hamoud B; Sima RM; Dinu MD; Gorecki GP; Popescu M; Gică N; Poenaru MO; Pleș L · Biomedicines · 2024
Narrative reviewflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Supplementation with oil rich in eicosapentaenoic acid, but not in docosahexaenoic acid, improves global cognitive function in healthy, young adults: results from randomized controlled trials.
Patan MJ; Kennedy DO; Husberg C; Hustvedt SO; Calder PC; Khan J; Forster J; Jackson PA · The American journal of clinical nutrition · 2021
Randomized trial310 participantsflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial.
Castle M; Fiedler N; Pop LC; Schneider SJ; Schlussel Y; Sukumar D; Hao L; Shapses SA · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
Randomized trialflagMental Focus forscienceVitamin D
- Vitamin D and executive function: a preliminary report.
Hansen AL; Dahl L; Bakke L; Thayer JF · Perceptual and motor skills · 2012
Cross-sectional study25 participantsflagMental Focus forscienceVitamin D
- Effects of Vitamin D Supplementation on Cognitive Function in Older Adults: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Methodology-Assessed Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Behrouzi R; Shahinfar H; Jazayeri S · Nutrition reviews · 2026
Meta-analysis9 studies pooledflagMental Focus forscienceVitamin D
- Maternal vitamin D concentrations are associated with faster childhood reaction time and response speed, but not with motor fluency and flexibility, at the age of 5-6 years: the Amsterdam Born Children and their Development (ABCD) Study.
Brouwer-Brolsma EM; Vrijkotte TGM; Feskens EJM · The British journal of nutrition · 2019
Cohort study1,854 participantsflagMental Focus forscienceVitamin D
- Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study.
Granic A; Hill TR; Kirkwood TB; Davies K; Collerton J; Martin-Ruiz C; von Zglinicki T; Saxby BK; Wesnes KA; Collerton D; Mathers JC; Jagger C · European journal of neurology · 2015
Cohort study775 participantsflagMental Focus forscienceVitamin D
- Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
Meta-analysis331 participants6 studies pooledflagMetabolism Boost forscienceOmega-3
- Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
Randomized trial38 participantsflagMetabolism Boost forscienceOmega-3
- Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
Randomized trial60 participantsflagMetabolism Boost flagSkin Health forscienceOmega-3
- The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
Randomized trial60 participantsflagMetabolism Boost forscienceOmega-3
- A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
Randomized trial200 participantsflagMetabolism Boost forscienceOmega-3
- Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
Randomized trial120 participantsflagMetabolism Boost forscienceVitamin D
- Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
Randomized trialflagMetabolism Boost forscienceVitamin D
- Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
Randomized trial92 participantsflagMetabolism Boost forscienceVitamin D
- The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
Meta-analysis630 participants8 studies pooledflagMetabolism Boost forscienceVitamin D
- The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
Meta-analysis1,528 participants24 studies pooledflagMetabolism Boost forscienceVitamin D
- Dietetic intervention in psoriatic arthritis: the DIETA trial.
Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
Randomized trial97 participantsflagSkin Health forscienceOmega-3
- Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
Randomized trial49 participantsflagSkin Health forscienceOmega-3
- Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
Randomized trial50 participantsflagSkin Health forscienceOmega-3
- Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
Randomized trial42 participantsflagSkin Health forscienceOmega-3