Activated B-Complex High Bioavailability

Activated B-Complex High Bioavailability

Swanson4.9 (3,679 ratings)
Format:Capsule Quantity: 60 Veggie Cap(s) · 60 servings
Goals
$17.69 $0.29 per serving

Product analysis

67 out of 100

Activated B-Complex High Bioavailability supplies B vitamins that help fill dietary gaps and support normal energy use and blood formation. Its activated forms do not establish extra energy or better mental performance when intake is already adequate.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality56

Riboflavin, B6 and B5 use favorable ingredient forms. Other forms are unspecified or cannot be judged confidently, so the same quality conclusion does not apply to every ingredient.

Ingredient Transparency90

Amounts are disclosed for all listed ingredients, and most forms are named. The forms of biotin, thiamin and PABA remain unstated, which limits complete comparison.

Value For Money49

Riboflavin and B6 provide the clearest value strengths. Choline and B5 look costly for their contributions, leaving mixed value across the formula.

Customer Satisfaction91

Customer feedback is very positive across thousands of ratings. That provides a substantial view of satisfaction, without showing that activated vitamins work better.

Product Focus60

The broad vitamin mix is most clearly suited to filling nutritional gaps. Its links to mood, cognition, hair and energy depend largely on inadequate intake, rather than a reliable boost for well-nourished adults.

Format
Capsule
Container
60 Veggie Cap(s)
Per serving
$0.29
Customer rating
4.9 · 3,679 ratings
Report analysis

Goals

Impact
Moderate effect
C+ Ingredient FitF PathwaysB+ EvidenceA Formulation Logic
Vitamin B5 · 25 mgRiboflavin · 25 mgThiamin · 36 mgVitamin B12 · 250 mcg

B12, folate, niacin, B6 and riboflavin support normal nutritional functions related to energy and fatigue. Their clearest role is filling a dietary gap, with no extra energy benefit implied by high amounts or activated forms. Unresolved thiamin and B5 amounts limit assessment.

How this product is rated for Energy

Ingredient fit66

The relevant ingredients are closely focused on the assessed energy-related roles. Smaller or unresolved amounts limit the contribution in the saved dose assessment.
Goal fit
The relevant ingredients are closely focused on the assessed energy-related roles.
Dose adequacy
Smaller or unresolved amounts limit the contribution in the saved dose assessment.

Pathways0

No meaningful contribution was recorded for the assessed direct energy mechanisms; nutritional support is considered separately.
Depth
No meaningful contribution was recorded for the assessed direct energy mechanisms; nutritional support is considered separately.
Breadth
The saved findings show limited coverage across the different direct energy mechanisms.

Evidence81

Vitamin B12 provides the strongest evidence contribution among the assessed ingredients, with practical benefit depending on context.
Evidence strength
Vitamin B12 provides the strongest evidence contribution among the assessed ingredients, with practical benefit depending on context.
Studied preparation
The ingredients assessed at relevant amounts match preparations recognized in the saved findings.

Formulation logic93

The assessed ingredients can contribute independently or have their required partner.
Partner coverage
The assessed ingredients can contribute independently or have their required partner.
Conflicts
No configured ingredient conflicts were identified in the saved findings.
Effective doses
Some assessed ingredients fall below the saved minimum amount threshold: Vitamin B1 (Thiamin), Vitamin B5.
Study evidence
Thiamin Disputed 12 studies
Impact
Moderate effect
C+ Ingredient FitF PathwaysA+ EvidenceA Formulation Logic
Biotin · 25 mcgNiacin · 50 mg NEVitamin B12 · 250 mcgRiboflavin · 25 mgThiamin · 36 mgVitamin B5 · 25 mgVitamin B6 · 25 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Riboflavin (Riboflavin 5-Phosphate)
25 mg 91
Niacinamide (Inositol Hexanicotinate)
50 mg NE
Vitamin B6 (Pyridoxal 5-Phosphate)
25 mg 82
Folate (Calcium L-5-Methyltetrahydrofolate)
400 mcg DFE
Vitamin B12 (Methylcobalamin)
250 mcg 67
Biotin
25 mcg
Choline (Choline Dihydrogen Citrate)
25 mg 50
Benfotiamine
36 mg 73
PABA
25 mg 78
Pantethine (Pantesin)
25 mg 63
Inositol (Inositol Hexaniacinate)
12.5 mg
Adults 18–50
Report overview
A+ Ingredient Form & Label QualityC Dose, Safety & Label TransparencyA- Value
Each serving provides 25 mg of vitamin B6, at a relatively low cost per milligram. The source is pyridoxal 5-phosphate.
How this ingredient is rated

Ingredient Form & Label Quality100

The source is pyridoxal 5-phosphate. The listed ingredients do not include artificial colors, titanium dioxide, or talc.
Vitamin B6 Form Identification
The source is pyridoxal 5-phosphate.
Clean Label and Excipient Purity
The listed ingredients do not include artificial colors, titanium dioxide, or talc.

Dose, Safety & Label Transparency60

The label states 25 mg of B6 per serving. The source is also named.
Vitamin B6 Dose & Safety Policy
Each serving provides 25 mg of vitamin B6. It is a relatively high amount.
Label Transparency
The label states the amount and source.

Value87

The cost per milligram of B6 is relatively low.
Vitamin B6 Price Efficiency
The cost per milligram of B6 is relatively low.
PABA · 25 mg OverallScore78
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving supplies 25 mg of PABA, with a high estimated whole-product cost per 100 mg of PABA. The amount is stated, but no specific quality grade is available. No artificial colors, titanium dioxide or hydrogenated oils are recorded.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is named, but a specific quality grade is not stated.
PABA Source & Grade
PABA is named without a specified quality grade.

Dose, Safety & Label Transparency95

The serving lists 25 mg of PABA. No artificial colors, titanium dioxide or hydrogenated oils are recorded among the other ingredients.
PABA Dosage Alignment
The serving contains 25 mg of PABA.
Label Disclosure Clarity
The PABA amount is stated separately.
Additive and Excipient Quality
No artificial colors, titanium dioxide or hydrogenated oils are recorded among the other ingredients.

Value40

The estimated whole-product cost per 100 mg of PABA is high; it includes the cost of the other ingredients.
Price per 100mg PABA
The estimated whole-product cost per 100 mg of PABA is high; it includes the cost of the other ingredients.
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
Each serving provides 25 mg of riboflavin at a moderate cost per serving. The form is Riboflavin 5-Phosphate. No artificial additives are indicated in the available information.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The form is Riboflavin 5-Phosphate.
Riboflavin Form Quality
The form is Riboflavin 5-Phosphate.

Dose, Safety & Label Transparency88

The serving lists 25 mg of riboflavin. No artificial additives are indicated in the available information.
Dosage for Energy & Metabolism
Each serving provides 25 mg of riboflavin.
R5P Elemental Yield Transparency
The riboflavin amount and form are listed.
Additive Purity
No artificial additives are indicated in the available information.

Value80

The cost per serving is moderate.
Price per Serving Value
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin