CellularActive Coenzyme B-Complex

CellularActive Coenzyme B-Complex

Bluebonnet4.8 (337 ratings)
Format:Capsule Quantity: 50 Capsule(s) · 50 servings
Goals

Product analysis

68 out of 100

CellularActive Coenzyme B-Complex supplies B vitamins that may help fill nutrient gaps affecting energy, mood and concentration. Several mixed sources omit their proportions, making detailed comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality70

Clearly identified B6, biotin and B5 forms support a favorable quality picture. Other named sources and unspecified mixture proportions leave some differences unresolved.

Ingredient Transparency77

All amounts and nearly all forms are disclosed. Six mixed-source entries omit proportions, so their totals do not show each source’s contribution.

Value For Money49

Riboflavin and B6 compare favorably on cost, while B5 and choline offer weaker value. Several other contributions are middling or uncertain.

Customer Satisfaction78

Customer ratings are strongly favorable. A moderate review pool gives that impression context without proving mood or energy benefits.

Product Focus64

B vitamins share nutritional roles across energy, mood and cognitive needs. Benefits are mainly relevant when intake is low, and the broader ingredient list does not establish extra effects.

Format
Capsule
Container
50 Capsule(s)
Per serving
$0.31
Customer rating
4.8 · 337 ratings
Report analysis

Goals

Impact
High effect
B Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 25 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 250 mcg

B12, folate and B6 help fill nutritional gaps that can cause anaemia and fatigue. Riboflavin, niacin and pantothenic acid also contribute to normal nutritional functions relevant to tiredness. Larger amounts and the declared vitamin forms do not establish extra energy when intake is adequate.

How this product is rated for Energy

Ingredient fit76

The B vitamins have a relevant nutritional or fatigue-related connection, but the amount comparison cannot establish clinical benefit.
Goal fit
The B vitamins provide the relevant connection, while the product's wider purposes affect its focus on energy.
Dose adequacy
The known quantities make a partial combined contribution to the saved comparison, rather than establishing a fatigue-treatment dose.

Pathways0

No contribution was recorded for the configured energy pathways; correction of nutrient-related fatigue is a separate role.
Depth
No contribution was recorded for the configured energy pathways; correction of nutrient-related fatigue is a separate role.
Breadth
None of the configured alertness, exercise-energy or stress-fatigue pathways received coverage.

Evidence81

B12 leads the saved evidence finding; its nutritional fatigue role is conditional on low intake or deficiency.
Evidence strength
B12 leads the saved evidence finding; its nutritional fatigue role is conditional on low intake or deficiency.
Studied preparation
The declared nutrient preparations are accepted in the saved finding; this does not show the complete product was clinically tested for fatigue.

Formulation logic100

The included ingredients require no additional partner in the saved findings, and no matching conflict was identified. Their minimum amount check is satisfied.
Partner coverage
No additional partner is required for the included ingredients under the saved findings.
Conflicts
No matching conflict was identified by the supplied checks.
Effective doses
All ingredients included in this check meet its minimum amount threshold; that finding does not prove routine fatigue relief.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 300 mcgNiacin · 25 mgVitamin B12 · 250 mcgRiboflavin · 25 mgThiamin · 25 mgVitamin B5 · 25 mgVitamin B6 · 25 mg

B vitamins help the body use carbohydrate, fat and protein for normal energy metabolism. Replacing inadequate intake supports these normal processes, but extra B vitamins have not been shown here to raise energy expenditure when intake is adequate.

How this product is rated for Metabolism Support

Ingredient fit75

The formula supplies nutrients involved in normal metabolism. Its favorable saved amount findings should not be read as evidence of a direct metabolic-rate increase.
Goal fit
The formula includes nutrients needed for normal metabolism, alongside other ingredients; this does not establish direct stimulation of energy expenditure.
Dose adequacy
The declared amounts provide partial coverage of the saved comparison ranges, which are not proven doses for increasing metabolic rate.

Pathways0

No direct thermogenic pathway receives a contribution; B-vitamin support for normal metabolism is a separate function.
Depth
No direct thermogenic pathway receives a contribution; B-vitamin support for normal metabolism is a separate function.
Breadth
No pathway reaches the saved coverage threshold, so broad support across the evaluated mechanisms is absent.

Evidence100

Thiamin leads the saved evidence finding, but its normal metabolic role does not demonstrate a boost in energy expenditure.
Evidence strength
Thiamin leads the saved evidence finding, but its normal metabolic role does not demonstrate a boost in energy expenditure.
Studied preparation
The saved finding accepts the evaluated preparations; this does not demonstrate that the listed forms increase metabolic rate or outperform alternatives.

Formulation logic100

No unmet partner requirement or configured conflict was found, and the recognized ingredients meet the saved amount threshold.
Partner coverage
The recognized ingredients have no unmet partner requirement in the saved findings; this does not establish additional benefit from combining them.
Conflicts
No configured ingredient conflict was detected in the supplied facts.
Effective doses
The recognized ingredients reach the saved amount threshold; that threshold does not establish a clinically effective thermogenic dose.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Cocarboxylase, Thiamine Mononitrate)
25 mg 65
Riboflavin (Riboflavin 5-Phosphate)
25 mg 79
Niacin (Inositol Hexanicotinate, Niacinamide)
25 mg 66
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
25 mg 81
Folate ((6S)-5-Methyltetrahydrofolic Acid, Folic Acid)
600 mcg DFE
Vitamin B12 (Methylcobalamin)
250 mcg 67
Biotin (D-Biotin)
300 mcg 66
Pantothenic Acid (Calcium D-Pantothenate)
25 mg 61
Choline (Choline Bitartrate)
10 mg 50
Inositol (Inositol Hexanicotinate)
25 mg
Para-Aminobenzoic Acid
25 mg 78
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free No Allergies Vegetarian
Report overview
A+ Ingredient Form & Label QualityC Dose, Safety & Label TransparencyA- Value
A serving provides 25 mg of B6, exceeding the European adult daily upper limit. The identified sources are pyridoxal 5-phosphate and pyridoxine hydrochloride, but their proportions are unknown.
How this ingredient is rated

Ingredient Form & Label Quality100

The identified sources are pyridoxal 5-phosphate and pyridoxine hydrochloride; their proportions are unknown. The saved facts flag no artificial dyes, titanium dioxide or talc.
Vitamin B6 Form Identification
The identified sources are pyridoxal 5-phosphate and pyridoxine hydrochloride; their proportions are unknown.
Clean Label and Excipient Purity
The saved facts flag no artificial dyes, titanium dioxide or talc.

Dose, Safety & Label Transparency60

A serving provides 25 mg of B6, exceeding the European adult daily upper limit. The B6 source is identified on the label.
Vitamin B6 Dose & Safety Policy
A serving provides 25 mg of B6, exceeding the European adult daily upper limit.
Label Transparency
The B6 source is identified on the label.

Value86

The whole-product price is about $0.013 per mg of B6.
Vitamin B6 Price Efficiency
The whole-product price is about $0.013 per mg of B6.
PABA · 25 mg OverallScore78
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving lists 25 mg of PABA, with the amount stated individually. Scaled from the whole-product serving price, the cost is about $1.28 per 100 mg of PABA.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The saved facts identify PABA but do not record a pharmaceutical-grade or purity claim.
PABA Source & Grade
PABA is named, while no specific grade or purity designation is recorded in the saved facts.

Dose, Safety & Label Transparency95

The serving lists 25 mg of PABA. None of the three assessed additive categories are recorded.
PABA Dosage Alignment
The recorded PABA amount is 25 mg per serving.
Label Disclosure Clarity
The PABA amount is individually recorded as 25 mg per serving.
Additive and Excipient Quality
The evaluated facts record no FD&C dyes, titanium dioxide or hydrogenated oils.

Value40

The serving price corresponds to about $1.28 per 100 mg of PABA when scaled from the whole-product price.
Price per 100mg PABA
Based on the whole-product serving price, the equivalent cost is about $1.28 per 100 mg of PABA.
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
Each serving provides 25 mg of riboflavin from plain riboflavin and riboflavin 5-phosphate. The proportions of those forms are not established, and the whole-product serving costs about $0.32.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Both plain riboflavin and riboflavin 5-phosphate are listed, but their proportions are not established.
Riboflavin Form Quality
Both plain riboflavin and riboflavin 5-phosphate are listed, but their proportions are not established.

Dose, Safety & Label Transparency88

25 mg of riboflavin is listed per serving, and no artificial additives were flagged in the available other-ingredients information.
Dosage for Energy & Metabolism
A serving provides 25 mg of riboflavin, a moderate amount in this evaluation.
R5P Elemental Yield Transparency
The amount of riboflavin is disclosed, so its nutrient yield is known.
Additive Purity
No artificial additives were flagged in the available other-ingredients information.

Value80

A whole-product serving costs about $0.32, a lower price in this comparison.
Price per Serving Value
A whole-product serving costs about $0.32, a lower price in this comparison.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin