B-100

B-100

NOW4.8 (10,643 ratings)
Format:Capsule Quantity: 250 Capsule(s) · 250 servings
Goals

Product analysis

71 out of 100

B-100 may help fill B-vitamin gaps that contribute to tiredness and impaired normal nutrient functions.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Ingredient-form quality varies, with some clearly named sources alongside less clearly described ingredients. Folate, biotin, inositol and PABA forms are unspecified, limiting a complete quality comparison.

Ingredient Transparency86

All ingredient amounts and several forms are stated for comparison. Folate, biotin, inositol and PABA are less clear because their forms are unspecified.

Value For Money59

Value is mixed, with favorable costs for riboflavin and B6 but weaker value for B5, choline and PABA. Several other ingredients lack reliable cost comparisons.

Customer Satisfaction93

Customer feedback is very positive. Many thousands of reviews provide a broad picture of buyer satisfaction.

Product Focus69

The clearest use is filling B-vitamin gaps that contribute to fatigue or impaired normal nutrient functions. Large amounts do not establish greater benefits or suitability for every user.

Format
Capsule
Container
250 Capsule(s)
Per serving
$0.12
Customer rating
4.8 · 10,643 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 100 mgThiamin · 100 mgVitamin B12 · 100 mcg

Riboflavin, B5, folate and niacin can help address fatigue linked to low intake, alongside vitamin B6. Their roles in normal metabolism do not establish extra energy when intake is adequate or make high amounts more effective. Vitamin B12 is present but falls below the saved minimum amount criterion.

How this product is rated for Energy

Ingredient fit85

The relevant nutrients receive the main saved allowances. The counted amounts reach the full comparison ranges.
Goal fit
The relevant nutrients supply the main saved ingredient connection; other actives and broader product purposes affect focus.
Dose adequacy
The counted amounts reach the full saved comparison allowances; exceeding them does not establish added energy benefit.

Pathways0

No contribution is assigned to the configured energy pathways. Nutritional correction remains a distinct role.
Depth
No contribution is assigned to the configured energy pathways, despite the separate nutrient allowances.
Breadth
No configured energy pathway reaches the saved breadth criterion; this does not negate a nutrient’s role in correcting low intake.

Evidence78

The strongest relevant support concerns low-intake fatigue rather than extra energy with adequate nutrition. Saved allowances do not resolve the supplied limits for routine use.
Evidence strength
Vitamin B2 (Riboflavin) anchors the saved evidence finding; its allowance does not establish extra energy in adults with adequate intake.
Studied preparation
The counted preparations receive the saved comparison allowance, without establishing superior energy effects for a particular form.

Formulation logic100

The counted ingredients meet the minimum amount criterion and have no missing required partner or identified configured conflict.
Partner coverage
No required ingredient partner is missing for the counted ingredients.
Conflicts
No configured ingredient conflict was identified; this does not establish individual suitability.
Effective doses
The counted ingredients meet the saved minimum amount criterion; this threshold does not establish a fatigue-treatment dose.
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA Formulation Logic
Folate · 680 mcg DFEVitamin B12 · 100 mcg

The B vitamins provide nutrients used in normal energy metabolism, while folate and B12 contribute to nutritional availability for blood formation. This can help fill low dietary intake, without establishing extra energy or disease prevention when intake is adequate. The larger amounts do not establish larger health benefits.

How this product is rated for Everyday Health

Ingredient fit85

The formula mixes counted nutritional ingredients with ingredients for other purposes, broadening its focus. The counted amounts only partly cover the saved comparison range.
Goal fit
The formula mixes counted nutritional ingredients with ingredients for other purposes, broadening its focus.
Dose adequacy
The counted amounts only partly cover the saved comparison range.

Pathways80

The strongest assigned area is energy metabolism cofactors. This describes the main nutritional connection, not demonstrated broad health improvement.
Depth
The strongest assigned area is energy metabolism cofactors. This describes the main nutritional connection, not demonstrated broad health improvement.
Breadth
Two areas reach the saved breadth requirement.

Evidence82

Vitamin B9 (Folate) leads the saved evidence finding. Its contribution remains conditional on the supplied context, without assuming improved outcomes above nutritional adequacy.
Evidence strength
Vitamin B9 (Folate) leads the saved evidence finding. Its contribution remains conditional on the supplied context, without assuming improved outcomes above nutritional adequacy.
Studied preparation
The counted preparations match the saved comparison; no chemical form or delivery method is established as superior.

Formulation logic93

The vitamin B6 amount reaches the configured high-amount conflict threshold. No missing required partner reduces the counted contribution.
Partner coverage
No missing required partner reduces the counted ingredients’ contribution; this does not establish a combination benefit.
Conflicts
The vitamin B6 amount reaches the configured high-amount conflict threshold.
Effective doses
The counted ingredients meet the saved amount requirement, which is a comparison threshold rather than a proven effective dose.
Study evidence
Folate Supportive 80 studies
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 100 mcgNiacin · 100 mgVitamin B12 · 100 mcgRiboflavin · 100 mgThiamin · 100 mgVitamin B5 · 100 mgVitamin B6 · 100 mg

B vitamins help the body carry out normal energy metabolism: thiamin supports carbohydrate use, riboflavin supplies enzyme cofactors, and pantothenic acid supports coenzyme A production. These necessary functions do not establish that extra vitamins raise resting or daily energy expenditure when intake is adequate. Large amounts alone do not establish greater calorie burning.

How this product is rated for Metabolism Support

Ingredient fit79

Recognized metabolic ingredients sit within a broader formula, reducing its focus on this particular goal. The supplied amounts contribute partly to the saved comparison; comparison amounts are not proven doses for increased energy expenditure.
Goal fit
Recognized metabolic ingredients sit within a broader formula, reducing its focus on this particular goal.
Dose adequacy
The supplied amounts contribute partly to the saved comparison; comparison amounts are not proven doses for increased energy expenditure.

Pathways0

No contribution was recorded for the specific energy-expenditure mechanisms considered.
Depth
No contribution was recorded for the specific energy-expenditure mechanisms considered.
Breadth
No specific mechanism reached the required coverage level.

Evidence100

Vitamin B1 (Thiamin) leads the saved evidence finding; its supplied scientific limitations still apply to claims about metabolic rate.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence finding; its supplied scientific limitations still apply to claims about metabolic rate.
Studied preparation
The contributing preparations matched those recognized in the saved result, without establishing that the complete product reproduces a trial regimen.

Formulation logic100

No required partner or configured conflict reduced the recognized contributions. All counted amounts reached the minimum comparison threshold.
Partner coverage
No missing required partner reduced the recognized contributions; this does not establish additional benefit from combining ingredients.
Conflicts
No configured ingredient conflict was identified in the supplied calculation.
Effective doses
All counted ingredients reached the minimum comparison threshold, which is not a proven minimum dose for a metabolic boost.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
100 mg 82
Riboflavin
100 mg 72
Niacin (Niacinamide)
100 mg 83
Vitamin B6 (Pyridoxine Hydrochloride)
100 mg 72
Folate
680 mcg DFE
Vitamin B12 (Cyanocobalamin)
100 mcg 21
Biotin
100 mcg
Pantothenic Acid (Calcium Pantothenate)
100 mg 70
Choline (Choline Bitartrate)
10 mg 50
Inositol
10 mg
PABA
10 mg 68
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
Each serving provides 100 mg of thiamin, a high-potency amount. The cost per amount of thiamin is moderate. It uses Thiamine Hydrochloride, a standard water-soluble form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Hydrochloride is a standard water-soluble form. The listed ingredients have no flagged artificial sweeteners or colors.
Thiamin Chemical Form
Thiamine Hydrochloride is a standard water-soluble form of thiamin.
Excipient Purity
The listed ingredients have no flagged artificial sweeteners or colors.

Dose, Safety & Label Transparency100

Each serving provides 100 mg of thiamin, a high-potency amount. The thiamin amount is clearly stated.
Thiamin Dosage Potency
Each serving provides 100 mg of thiamin, a high-potency amount.
Label Transparency & Proprietary Blends
The thiamin amount per serving is clearly stated.

Value70

The cost per amount of thiamin is moderate.
Price per Declared Dose
The cost per amount of thiamin is moderate.
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyC Value
A serving provides 100 mg of niacin, and has a moderate cost per serving. It uses niacinamide, a named form of vitamin B3.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide is the form used for general support.
Niacin Form & Goal Alignment
Niacinamide is the form used for general support.
Precursor Source Quality
Niacinamide is a standard form of vitamin B3.

Dose, Safety & Label Transparency92

The serving provides 100 mg of niacin. The form is named, but no no-flush claim is stated.
Clarity of Chemical Form
The niacin form is clearly named as niacinamide.
Form-Specific Dosage Efficacy
The serving provides 100 mg of niacin.
Flush Risk & Safety Labeling
Niacinamide is used, but a no-flush claim is not stated.

Value60

The cost per serving is moderate.
Price Per Effective Serving
The cost per serving is moderate.
Riboflavin · 100 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
The serving provides 100 mg of riboflavin, a high amount, at a low cost per serving. It uses standard riboflavin, which needs conversion in the liver. The listed ingredients include no artificial colors, flavors or synthetic sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

Standard riboflavin requires conversion before use in energy metabolism.
Riboflavin Form Quality
It uses standard riboflavin, which needs conversion in the liver.

Dose, Safety & Label Transparency100

Each serving provides 100 mg of riboflavin. The ingredient list contains no listed artificial colors, flavors or synthetic sweeteners.
Dosage for Energy & Metabolism
A serving supplies 100 mg of riboflavin, a high amount.
R5P Elemental Yield Transparency
The compound-yield concern for riboflavin 5-phosphate does not apply to standard riboflavin.
Additive Purity
The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.

Value100

The cost per serving is low.
Price per Serving Value
The serving price is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate