Kyolic Omega-3

Kyolic Omega-3

Kyolic4.8 (1,913 ratings)
Format:Softgel Quantity: 180 Softgel(s) · 90 servings
Goals
$43.61 $0.48 per serving

Product analysis

54 out of 100

Kyolic Omega-3 provides EPA and DHA for heart-related nutritional support. Their amounts are below the larger exposures behind the lipid findings, so the practical effect may be limited.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality21

The EPA and DHA preparation details are unspecified, limiting comparisons between sources. The garlic preparation also lacks the detail needed for a source-quality judgment.

Ingredient Transparency58

EPA and DHA are separately quantified, helping you compare the main active amounts. The vitamin E amount and part of the mixture breakdown remain unclear.

Value For Money64

EPA compares favorably for cost, while DHA offers a more moderate value contribution. Garlic value cannot be judged reliably.

Customer Satisfaction87

Customer ratings show very favorable satisfaction. A substantial number of ratings makes buyer opinion more established.

Product Focus68

EPA and DHA give the formula a clear cardiovascular focus, with more limited brain-related support. Their nutritional roles do not imply an immediate improvement in concentration.

Format
Softgel
Container
180 Softgel(s)
Per serving
$0.48
Customer rating
4.8 · 1,913 ratings
Report analysis

Goals

Inflammation
Impact
Moderate effect
C- Ingredient FitF PathwaysC+ EvidenceA Formulation Logic
Fish Oil · 2000 mgVitamin E · 10 IU

EPA and DHA may lower some blood markers of inflammation. A change in those markers does not necessarily mean you’ll notice symptom relief or receive a broad anti-inflammatory benefit. The declared EPA and DHA amounts matter more for this connection than the total weight of fish oil.

How this product is rated for Inflammation

Ingredient fit58

EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Goal fit
EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Dose adequacy
One serving supplies 400 mg of DHA (docosahexaenoic acid); the numerical comparison alone does not demonstrate an anti-inflammatory effect.

Pathways16

EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Depth
EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Breadth
The described ingredient roles do not imply broad relief across different inflammatory conditions.

Evidence70

EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Evidence strength
EPA and DHA may lower inflammatory blood markers; symptom relief is a separate outcome.
Studied preparation
The relevant ingredient preparations permit comparison, but that does not guarantee a practical anti-inflammatory benefit.

Formulation logic92

No additional partner is required for the described roles, and no particular ingredient conflict is identified.
Partner coverage
No additional partner is required for the described ingredient roles.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Some amounts do not reach lower comparisons: Vitamin E. This is not proof of ineffectiveness.
Study evidence
Fish Oil Supportive 68 studies
Vitamin E Supportive 20 studies
Impact
High effect
C+ Ingredient FitC- PathwaysA+ EvidenceA+ Formulation Logic
EPA (Eicosapentaenoic Acid) · 600 mg

EPA is linked mainly to triglyceride-related support, while DHA has more limited lipid and vascular evidence. Their separately declared amounts establish active content, unlike total fish-oil mass. Routine supplementation has not established prevention of major cardiovascular events, and prescription EPA findings in selected high-risk patients do not transfer to this product. The two fats do not imply an extra benefit from their combination.

How this product is rated for Heart Health

Ingredient fit68

EPA and DHA provide the main recognized connection. EPA and DHA provide partial exposure coverage in the saved comparison, without establishing a proven effective dose.
Goal fit
EPA and DHA are the main recognized focus. Other actives broaden the formula beyond these heart-related roles.
Dose adequacy
EPA and DHA provide partial exposure coverage in the saved comparison, without establishing a proven effective dose.

Pathways56

The findings center on triglyceride handling, with narrow coverage across the evaluated functions.
Depth
The main recognized connection is triglyceride handling.
Breadth
The breadth finding centers on triglyceride handling, rather than broad coverage of different heart-health functions.

Evidence100

EPA supplies the strongest evidence finding here, chiefly for triglyceride support rather than routine event prevention.
Evidence strength
EPA supplies the strongest evidence finding here, chiefly for triglyceride support rather than routine event prevention.
Studied preparation
The saved preparation check recognizes the counted declarations; this does not establish product-specific trial results.

Formulation logic100

EPA and DHA have no identified required-partner gap or configured conflict. All ingredients counted for this check meet its minimum exposure criterion; that criterion is not proof of clinical benefit.
Partner coverage
No missing required partner was identified among the counted ingredients; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
All ingredients counted for this check meet its minimum exposure criterion; that criterion is not proof of clinical benefit.
Study evidence
Cardiovascular Support
Impact
High effect
B- Ingredient FitC PathwaysB+ EvidenceA Formulation Logic
Fish Oil · 2000 mgVitamin E · 10 IU

EPA and DHA contribute to triglyceride lowering, with the supplied studies using larger daily amounts of each fatty acid than this serving’s 600 mg EPA and 400 mg DHA. The separate declarations support a limited exposure comparison without inferring a combined fish-oil active amount. Their lipid-marker role does not establish prevention of cardiovascular events, and the unknown vitamin E amount adds no established cardiovascular benefit.

How this product is rated for Cardiovascular Support

Ingredient fit73

Relevant cardiovascular ingredients sit within a broader formula with other purposes. The declared amounts provide varying exposure to relevant ingredients; comparison with study amounts does not establish a daily regimen.
Goal fit
Relevant cardiovascular ingredients sit within a broader formula with other purposes.
Dose adequacy
The declared amounts provide varying exposure to relevant ingredients; comparison with study amounts does not establish a daily regimen.

Pathways60

Triglyceride metabolism is the strongest represented area, with benefit expectations limited to the supplied lipid-marker findings.
Depth
Triglyceride metabolism is the strongest represented area, with benefit expectations limited to the supplied lipid-marker findings.
Breadth
One cardiovascular area meets the saved coverage threshold, so the support is concentrated rather than broad.

Evidence83

EPA supports a triglyceride-marker role; the supplied evidence does not establish cardiovascular-event prevention.
Evidence strength
EPA supports a triglyceride-marker role; the supplied evidence does not establish cardiovascular-event prevention.
Studied preparation
The saved preparation comparison accepts the qualifying ingredients, but that finding does not extend the evidence beyond the populations and outcomes described.

Formulation logic92

The qualifying ingredients have no missing required partners or matched conflicts in the supplied checks.
Partner coverage
No required partner is missing for the credited ingredients; this does not establish an extra benefit from combining them.
Conflicts
No matching formulation conflict was identified in the supplied checks.
Effective doses
The other qualifying ingredients meet the saved amount threshold; vitamin E’s unresolved amount does not.
Study evidence
Fish Oil Supportive 185 studies
Vitamin E Mixed 79 studies
Mental Focus
Impact
Moderate effect
C Ingredient FitD+ PathwaysC- EvidenceA+ Formulation Logic

DHA and EPA contribute to brain-related nutritional support. The serving provides 400 mg DHA and 600 mg EPA, while the supplied evidence concerns repeated intake and does not support expecting an immediate improvement in focus.

How this product is rated for Mental Focus

Ingredient fit63

Focus-related ingredients sit within a formula serving broader purposes. The assessed quantities provide a meaningful but incomplete match to the saved benchmarks.
Goal fit
Focus-related ingredients sit within a formula serving broader purposes.
Dose adequacy
The assessed quantities provide a meaningful but incomplete match to the saved benchmarks.

Pathways50

The main recorded contribution relates to brain-cell maintenance and signalling. One main mechanism meets the saved coverage benchmark, so support is relatively focused.
Depth
The main recorded contribution relates to brain-cell maintenance and signalling.
Breadth
One main mechanism meets the saved coverage benchmark, so support is relatively focused.

Evidence56

EPA (Eicosapentaenoic Acid) provides the strongest evidence contribution among the assessed ingredients. EPA matches a studied preparation in the saved assessment; DHA does not.
Evidence strength
EPA (Eicosapentaenoic Acid) provides the strongest evidence contribution among the assessed ingredients.
Studied preparation
EPA matches a studied preparation in the saved assessment; DHA does not.

Formulation logic100

The assessed ingredients can contribute independently or have their required partners. No ingredient conflict was flagged by the saved checks.
Partner coverage
The assessed ingredients can contribute independently or have their required partners.
Conflicts
No ingredient conflict was flagged by the saved checks.
Effective doses
All counted ingredients meet the saved minimum amount threshold.
Study evidence

Ingredients

IngredientAmount per servingScore
Vitamin E (D-Alpha-Tocopherol)
10 IU 44
Omega-3 Fish Oil concentrate
2000 mg 63
Eicosapentaenoic Acid
600 mg 69
Docosahexaenoic Acid
400 mg 53
Aged Garlic extract powder
240 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
D+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyB+ Value
A serving provides 600 mg of EPA and 400 mg of DHA, giving it more EPA than DHA. Its EPA costs about $0.81 per gram.
How this ingredient is rated

Active Ingredient Quality & Bioavailability50

The EPA molecular form is unresolved in the available information. EPA is only part of the stated fish oil amount.
Molecular Form and Bioavailability
The available information does not establish the molecular form; an ethyl ester form cannot be assumed.
EPA Concentration Density
EPA makes up about 30% of the stated fish oil amount per serving.
Oxidation Protection
Tocopherols are included; their presence does not measure the oil’s freshness.

Dose, Safety & Label Transparency82

The serving provides 600 mg EPA and 400 mg DHA.
Absolute EPA Dose per Serving
Each serving provides 600 mg of EPA.
EPA-Centric Ratio
The serving has 600 mg of EPA and 400 mg of DHA, so it contains more EPA than DHA.
Purity and Contaminant Testing
The oil is described as purified, but the saved evaluation does not establish a qualifying contaminant-specific testing or certification claim.

Value80

At about $0.81 per gram of EPA, the EPA cost is relatively low in this comparison.
Price per Gram of EPA
The estimate uses the stated EPA amount and price per whole-product serving.
D Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB- Value
Fish Oil · 2000 mg OverallScore63
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyB+ Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  2. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  5. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  6. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  7. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  8. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  9. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  10. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  11. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
    Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Saito Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Japan EPA lipid intervention study (JELIS) Investigators · Lancet (London, England) · 2007
    Randomized trial18,645 participantsHeart Health forEPA (Eicosapentaenoic Acid)
  12. Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).
    Saito Y; Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; JELIS Investigators, Japan · Atherosclerosis · 2008
    Randomized trial14,981 participantsHeart Health forEPA (Eicosapentaenoic Acid)
  13. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis.
    Dinu M; Sofi F; Lotti S; Colombini B; Mattioli AV; Catapano AL; Casula M; Baragetti A; Wong ND; Steg PG; Ambrosio G · European journal of preventive cardiology · 2024
    Meta-analysis134,144 participants18 studies pooledHeart Health forEPA (Eicosapentaenoic Acid)
  14. Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.
    Matsuzaki M; Yokoyama M; Saito Y; Origasa H; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Matsuzawa Y; JELIS Investigators · Circulation journal : official journal of the Japanese Circulation Society · 2009
    Randomized trialHeart Health forEPA (Eicosapentaenoic Acid)
  15. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association.
    Skulas-Ray AC; Wilson PWF; Harris WS; Brinton EA; Kris-Etherton PM; Richter CK; Jacobson TA; Engler MB; Miller M; Robinson JG; Blum CB; Rodriguez-Leyva D; de Ferranti SD; Welty FK; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology · Circulation · 2020
    OtherHeart Health forEPA (Eicosapentaenoic Acid)
  16. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsInflammation forFish Oil
  17. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsInflammation forFish Oil
  18. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsInflammation forFish Oil
  19. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsInflammation forFish Oil
  20. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledInflammation forFish Oil