B-100 Complex

B-100 Complex

Nature Made4.6 (57 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$14.59 $0.24 per serving

Product analysis

67 out of 100

B-100 Complex may help with tiredness caused by low B-vitamin intake and supports normal use of food for energy. Several unspecified forms make ingredient comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Niacin and B6 are clearly identified, and B5 uses a favorable form. Some other forms are unspecified or cannot be judged confidently, leaving quality across the mixture less clear.

Ingredient Transparency88

Amounts are disclosed throughout the formula, allowing serving comparisons. Riboflavin, folate and biotin forms are omitted.

Value For Money56

B6 and the serving cost associated with riboflavin offer favorable value. Thiamin and B5 are less economical, giving the combination an uneven value picture.

Customer Satisfaction69

Customer ratings are positive, but come from a small number of buyers. The limited feedback makes the satisfaction picture less settled.

Product Focus71

The clearest role is filling B-vitamin gaps that can affect tiredness and normal use of food for energy. High amounts do not establish extra energy or greater calorie burning when intake is already adequate.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.24
Customer rating
4.6 · 57 ratings
Report analysis

Goals

Impact
High effect
A Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 100 mgThiamin · 100 mgVitamin B12 · 100 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
A- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 100 mcgNiacin · 100 mgVitamin B12 · 100 mcgRiboflavin · 100 mgThiamin · 100 mgVitamin B5 · 100 mgVitamin B6 · 100 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Mononitrate)
100 mg 76
Riboflavin
100 mg 72
Niacin (Niacinamide)
100 mg 83
Vitamin B6 (Pyridoxine Hydrochloride)
100 mg 72
Folate
665 mcg DFE
Vitamin B12 (Cyanocobalamin)
100 mcg
Biotin
100 mcg
Pantothenic Acid (D-Calcium Pantothenate)
100 mg 70
Calcium (Dibasic Calcium Phosphate)
70 mg
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving provides 100 mg of thiamin, a high amount, at a high cost for the amount. It uses Thiamine Mononitrate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Mononitrate is a standard water-soluble form of thiamin. The available ingredient information does not indicate the specified artificial colors or sweeteners.
Thiamin Chemical Form
Thiamine Mononitrate is a standard water-soluble form of thiamin.
Excipient Purity
The available ingredient information does not indicate the specified artificial colors or sweeteners.

Dose, Safety & Label Transparency100

A serving provides 100 mg of thiamin, a high amount for targeted metabolic support. The thiamin amount per serving is stated.
Thiamin Dosage Potency
A serving provides 100 mg of thiamin, a high amount for targeted metabolic support.
Label Transparency & Proprietary Blends
The thiamin amount per serving is stated.

Value40

The cost per amount of thiamin is high.
Price per Declared Dose
The cost per amount of thiamin is high.
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyC Value
A serving provides 100 mg of niacin. The cost per serving is moderate. The niacin source is Niacinamide. The form is clearly named.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin source is Niacinamide.
Niacin Form & Goal Alignment
The niacin source is Niacinamide.
Precursor Source Quality
The niacin source is Niacinamide.

Dose, Safety & Label Transparency92

A serving provides 100 mg of niacin. The form is named, but no explicit no-flush claim is available.
Clarity of Chemical Form
The niacin source is Niacinamide.
Form-Specific Dosage Efficacy
A serving provides 100 mg of niacin.
Flush Risk & Safety Labeling
No explicit no-flush claim is available.

Value60

The cost per serving is moderate.
Price Per Effective Serving
The cost per serving is moderate.
Riboflavin · 100 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
The 100 mg of riboflavin per serving is a high amount, at a low cost per serving. It uses standard riboflavin, which requires conversion in the liver. No artificial colors, flavors or synthetic sweeteners are listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

It uses standard riboflavin, which requires conversion in the liver.
Riboflavin Form Quality
It uses standard riboflavin, which requires conversion in the liver.

Dose, Safety & Label Transparency100

Each serving provides 100 mg of riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
Dosage for Energy & Metabolism
Each serving provides 100 mg of riboflavin, a high amount.
R5P Elemental Yield Transparency
The stated amount is riboflavin; phosphate yield ambiguity does not apply.
Additive Purity
No artificial colors, flavors or synthetic sweeteners are listed.

Value100

The cost per serving is low.
Price per Serving Value
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin