B-100 Complex

B-100 Complex

21st Century4.7 (4,991 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$9.49 $0.15 per serving

Product analysis

68 out of 100

B-100 Complex can help fill B-vitamin gaps relevant to normal energy use and blood-cell formation. It offers favorable value for B6 and riboflavin, though value varies across the blend.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality59

Several B-vitamin forms are clearly identified, allowing useful source comparisons. Other form quality remains uncertain, and the conventional riboflavin preparation does not establish a special advantage.

Ingredient Transparency73

Listed amounts and most ingredient forms are disclosed, supporting serving comparisons. Folate and biotin forms and the calcium-mixture proportions remain unspecified.

Value For Money56

Value is mixed, with favorable comparisons for B6 and riboflavin. B5 is relatively costly, and several other nutrient comparisons remain uncertain.

Customer Satisfaction89

Customer ratings are very positive across several thousand reviews. The broad feedback describes satisfaction without establishing an energy boost.

Product Focus73

The main purpose is meeting B-vitamin needs relevant to normal energy use and blood formation. B6 reaches a high amount per serving, raising a suitability concern without establishing extra benefit.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.15
Customer rating
4.7 · 4,991 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 100 mgThiamin · 100 mgVitamin B12 · 100 mcg

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin can help address tiredness associated with their respective deficiencies. Their normal roles in metabolism do not establish extra energy when nutritional intake is adequate. Higher amounts or particular vitamin forms do not establish additional fatigue relief.

How this product is rated for Energy

Ingredient fit90

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin supplies the relevant ingredient connection to this goal. The declared serving meets the saved amount references; more does not establish greater benefit.
Goal fit
Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin supplies the relevant ingredient connection to this goal.
Dose adequacy
The declared serving meets the saved amount references; more does not establish greater benefit.

Pathways0

No direct alertness or exercise-energy mechanism was identified; the relevant role is nutritional adequacy.
Depth
No direct alertness or exercise-energy mechanism was identified; the relevant role is nutritional adequacy.
Breadth
No evaluated mechanism reached the saved coverage requirement.

Evidence78

The relevant support concerns correcting nutrient deficiencies rather than boosting energy with adequate intake.
Evidence strength
The relevant support concerns correcting nutrient deficiencies rather than boosting energy with adequate intake.
Studied preparation
The saved preparation check found matches, without establishing general benefit or superiority of these forms.

Formulation logic100

No missing ingredient partner requirement was identified. None of the evaluated ingredient conflicts was identified.
Partner coverage
No missing ingredient partner requirement was identified.
Conflicts
None of the evaluated ingredient conflicts was identified.
Effective doses
All included ingredients meet the saved minimum amount requirement; this does not establish a clinically effective fatigue regimen.
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A Ingredient FitB+ PathwaysB+ EvidenceA Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 100 mcg

B vitamins contribute to normal energy metabolism, while folate and B12 contribute to blood formation. Calcium and vitamin D contribute to bone and mineral nutrition when intake falls short. These nutrients can help fill dietary gaps; amounts above nutritional adequacy do not establish additional general-health benefits. Vitamin B6 reaches 100 mg per serving, triggering the configured high-amount concern.

How this product is rated for Everyday Health

Ingredient fit90

The retained nutrients provide nutritional contributions, with the serving amounts determining how fully the saved references are covered.
Goal fit
The retained nutrients account for the formula’s active focus, although their nutritional roles extend beyond this goal.
Dose adequacy
Serving amounts provide uneven coverage of the saved references, with unresolved quantities contributing no amount coverage.

Pathways80

The strongest saved area is energy metabolism cofactors; breadth depends on the other retained nutrient contributions.
Depth
The saved findings are strongest for energy metabolism cofactors, reflecting the retained nutrients’ nutritional roles.
Breadth
The saved findings cover energy metabolism cofactors, one-carbon metabolism and blood formation.

Evidence82

Vitamin B9 (Folate) provides the strongest saved evidence connection, limited here to conditional nutritional usefulness.
Evidence strength
Vitamin B9 (Folate) leads the saved evidence finding; its practical general-health role is filling a dietary gap rather than guaranteeing disease prevention.
Studied preparation
The retained ingredients meeting the amount threshold match recognized preparation categories; no superior form or delivery benefit is established.

Formulation logic93

Vitamin B6 reaches 100 mg per serving, triggering the configured high-amount concern.
Partner coverage
The saved findings identify no missing required ingredient partner.
Conflicts
Vitamin B6 reaches 100 mg per serving, triggering the configured high-amount concern.
Effective doses
All retained nutrients meet the saved amount threshold, which is a comparison reference rather than proof of added health benefits.
Study evidence
Folate Supportive 80 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 100 mcgNiacin · 100 mgVitamin B12 · 100 mcgRiboflavin · 100 mgThiamin · 100 mgVitamin B5 · 100 mgVitamin B6 · 100 mg

B vitamins support the normal processes that turn food into usable energy. Their physiological roles and serving amounts do not establish a faster resting metabolic rate when intake is adequate. The supplied evidence therefore supports normal nutrient function rather than a demonstrated increase in whole-body energy expenditure.

How this product is rated for Metabolism Support

Ingredient fit83

The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.
Goal fit
The formula combines ingredients connected to metabolism with other actives, reducing its specific focus on energy expenditure.
Dose adequacy
The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.

Pathways0

No contribution is established across the assessed energy-expenditure pathways.
Depth
No contribution is established across the assessed energy-expenditure pathways.
Breadth
No assessed pathway reaches the saved coverage threshold, leaving broad energy-expenditure support unestablished.

Evidence100

Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Studied preparation
The contributing forms meet the saved preparation criteria; this does not transfer findings from other outcomes into a thermogenic benefit.

Formulation logic100

The contributing ingredients have no missing required partners or configured conflicts. Their amounts meet the saved minimum comparison threshold.
Partner coverage
No required partner is missing among contributing ingredients; this does not establish added thermogenesis from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied calculation.
Effective doses
All contributing ingredients meet the saved minimum amount threshold; this comparison threshold is not proof of a clinical thermogenic effect.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Vitamin B1 (Thiamine Mononitrate)
100 mg 76
Vitamin B2 (Riboflavin)
100 mg 72
Niacin (Niacinamide)
100 mg 83
Vitamin B6 (Pyridoxine Hydrochloride)
100 mg 70
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
100 mcg 21
Biotin
100 mcg
Pantothenic Acid (D-Calcium Pantothenate)
100 mg 70
Calcium (Calcium Carbonate, Dicalcium Phosphate)
160 mg
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving provides 100 mg of thiamin as thiamine mononitrate, a standard water-soluble form. The whole-product serving price works out to about $0.16 per 100 mg of thiamin.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The source is thiamine mononitrate, a standard water-soluble form. The evaluation found no configured sweetener or color flags in the available other-ingredient information.
Thiamin Chemical Form
The source is thiamine mononitrate, a standard water-soluble form of thiamin.
Excipient Purity
The evaluation found no configured sweetener or color flags in the available other-ingredient information.

Dose, Safety & Label Transparency100

A serving provides 100 mg of thiamin, with thiamine mononitrate identified as the source.
Thiamin Dosage Potency
A serving provides 100 mg of thiamin.
Label Transparency & Proprietary Blends
The thiamin amount is recorded as 100 mg per serving and thiamine mononitrate is identified as its source.

Value40

Based on the whole-product serving price, the cost is about $0.16 per 100 mg of thiamin.
Price per Declared Dose
Based on the whole-product serving price, the cost is about $0.16 per 100 mg of thiamin.
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyC Value
A serving provides 100 mg of niacin as niacinamide. Niacinamide is generally less associated with flushing than nicotinic acid.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin is supplied as niacinamide, a standard form of vitamin B3.
Niacin Form & Goal Alignment
Niacinamide provides niacin in a standard form for general use.
Precursor Source Quality
The identified source is niacinamide; the available facts do not identify an NR or NMN precursor.

Dose, Safety & Label Transparency92

A serving supplies 100 mg of niacin as niacinamide. Niacinamide is generally less associated with flushing than nicotinic acid.
Clarity of Chemical Form
The niacin amount and niacinamide form are identified in the stored information.
Form-Specific Dosage Efficacy
A serving supplies 100 mg of niacin as niacinamide.
Flush Risk & Safety Labeling
Niacinamide is generally less associated with flushing than nicotinic acid; the available facts do not identify a no-flush claim.

Value60

The whole-product price is about $0.16 per serving, a middle-range price for a niacin comparison.
Price Per Effective Serving
The whole-product price is about $0.16 per serving, a middle-range price for a niacin comparison.
Riboflavin · 100 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
A serving provides 100 mg of standard riboflavin, which the body converts to active forms. It costs about $0.16, a relatively low price per whole-product serving.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

The standard form of riboflavin needs conversion to active forms in the body.
Riboflavin Form Quality
The identified form is standard riboflavin, which the body converts to active forms.

Dose, Safety & Label Transparency100

Each serving lists 100 mg riboflavin. No artificial dyes or synthetic sweeteners were identified in the available other-ingredients information.
Dosage for Energy & Metabolism
A serving lists 100 mg of riboflavin.
R5P Elemental Yield Transparency
The separate phosphate-yield question does not apply to standard riboflavin.
Additive Purity
No artificial dyes or synthetic sweeteners were identified in the available other-ingredients information.

Value100

The price is about $0.16, a relatively low price per whole-product serving.
Price per Serving Value
The price is about $0.16 per whole-product serving.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate