B-50 Complex

B-50 Complex

21st Century4.7 (9,744 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$5.37 $0.08 per serving

Product analysis

67 out of 100

B-50 Complex supports normal use of food for energy when B-vitamin intake is low. Its low cost across several key B vitamins is more convincing than an expectation of extra energy with adequate nutrition.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality53

Several B vitamins have clearly identified sources, including niacinamide and pyridoxine hydrochloride. Folate and biotin preparation details remain unspecified, while other source comparisons are less certain.

Ingredient Transparency73

Most B-vitamin forms and all listed amounts are disclosed, helping serving comparisons. Folate and biotin details and the split between calcium sources are missing.

Value For Money63

Riboflavin, niacin and B6 compare favorably for cost. Thiamin is less compelling and several other contributions lack a reliable comparison, leaving some uncertainty about the extras.

Customer Satisfaction90

Customer ratings indicate favorable satisfaction. The large review pool gives a more established view of buyer opinion.

Product Focus70

The formula has a concentrated B-vitamin purpose across normal metabolism and energy use. Benefits mainly concern inadequate intake rather than a faster metabolic rate or added energy once needs are met.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.08
Customer rating
4.7 · 9,744 ratings
Report analysis

Goals

Impact
High effect
A Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 10 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin can help address tiredness associated with their respective deficiencies. Their normal roles in metabolism do not establish extra energy when nutritional intake is adequate. Higher amounts or particular vitamin forms do not establish additional fatigue relief.

How this product is rated for Energy

Ingredient fit92

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin supplies the relevant ingredient connection to this goal. The declared serving only partly meets the saved amount references; a serving does not establish repeated daily exposure.
Goal fit
Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5, riboflavin supplies the relevant ingredient connection to this goal.
Dose adequacy
The declared serving only partly meets the saved amount references; a serving does not establish repeated daily exposure.

Pathways0

No direct alertness or exercise-energy mechanism was identified; the relevant role is nutritional adequacy.
Depth
No direct alertness or exercise-energy mechanism was identified; the relevant role is nutritional adequacy.
Breadth
No evaluated mechanism reached the saved coverage requirement.

Evidence78

The relevant support concerns correcting nutrient deficiencies rather than boosting energy with adequate intake.
Evidence strength
The relevant support concerns correcting nutrient deficiencies rather than boosting energy with adequate intake.
Studied preparation
The saved preparation check found matches, without establishing general benefit or superiority of these forms.

Formulation logic100

No missing ingredient partner requirement was identified. None of the evaluated ingredient conflicts was identified.
Partner coverage
No missing ingredient partner requirement was identified.
Conflicts
None of the evaluated ingredient conflicts was identified.
Effective doses
All included ingredients meet the saved minimum amount requirement; this does not establish a clinically effective fatigue regimen.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
A- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 10 mgVitamin B6 · 50 mg

B vitamins support the normal processes that turn food into usable energy. Their physiological roles and serving amounts do not establish a faster resting metabolic rate when intake is adequate. The supplied evidence therefore supports normal nutrient function rather than a demonstrated increase in whole-body energy expenditure.

How this product is rated for Metabolism Support

Ingredient fit85

The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.
Goal fit
The formula combines ingredients connected to metabolism with other actives, reducing its specific focus on energy expenditure.
Dose adequacy
The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.

Pathways0

No contribution is established across the assessed energy-expenditure pathways.
Depth
No contribution is established across the assessed energy-expenditure pathways.
Breadth
No assessed pathway reaches the saved coverage threshold, leaving broad energy-expenditure support unestablished.

Evidence100

Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Studied preparation
The contributing forms meet the saved preparation criteria; this does not transfer findings from other outcomes into a thermogenic benefit.

Formulation logic100

The contributing ingredients have no missing required partners or configured conflicts. Their amounts meet the saved minimum comparison threshold.
Partner coverage
No required partner is missing among contributing ingredients; this does not establish added thermogenesis from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied calculation.
Effective doses
All contributing ingredients meet the saved minimum amount threshold; this comparison threshold is not proof of a clinical thermogenic effect.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Mononitrate)
50 mg 76
Riboflavin
50 mg 72
Niacin (Niacinamide)
50 mg 81
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 72
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (D-Calcium Pantothenate)
10 mg
Calcium (Calcium Carbonate, Dicalcium Phosphate)
130 mg
Gluten Free Adults 18–50
Report overview
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value
A serving provides 50 mg of niacin as niacinamide. Niacinamide is generally less associated with flushing than nicotinic acid.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin is supplied as niacinamide, a standard form of vitamin B3.
Niacin Form & Goal Alignment
Niacinamide provides niacin in a standard form for general use.
Precursor Source Quality
The identified source is niacinamide; the available facts do not identify an NR or NMN precursor.

Dose, Safety & Label Transparency67

A serving supplies 50 mg of niacin as niacinamide. Niacinamide is generally less associated with flushing than nicotinic acid.
Clarity of Chemical Form
The niacin amount and niacinamide form are identified in the stored information.
Form-Specific Dosage Efficacy
A serving supplies 50 mg of niacin as niacinamide.
Flush Risk & Safety Labeling
Niacinamide is generally less associated with flushing than nicotinic acid; the available facts do not identify a no-flush claim.

Value100

The whole-product price is about $0.09 per serving, a relatively low price for a niacin comparison.
Price Per Effective Serving
The whole-product price is about $0.09 per serving, a relatively low price for a niacin comparison.
A Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
The 50 mg of B6 per serving exceeds the European adult daily upper limit on its own. The source is pyridoxine hydrochloride, and talc is recorded among the other ingredients.
How this ingredient is rated

Ingredient Form & Label Quality94

The B6 source is identified as pyridoxine hydrochloride. Talc is recorded among the other ingredients.
Vitamin B6 Form Identification
The identified vitamin B6 source is pyridoxine hydrochloride.
Clean Label and Excipient Purity
Talc is recorded among the other ingredients.

Dose, Safety & Label Transparency37

The 50 mg of B6 per serving exceeds the European adult daily upper limit on its own. The B6 source is disclosed.
Vitamin B6 Dose & Safety Policy
The 50 mg of B6 per serving exceeds the European adult daily upper limit on its own.
Label Transparency
The chemical source of the B6 is identified.

Value100

At about $0.0018 per mg of B6, based on the whole-product price, the B6 cost is low in the comparison.
Vitamin B6 Price Efficiency
At about $0.0018 per mg of B6, based on the whole-product price, the B6 cost is low in the comparison.
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving provides 50 mg of thiamin as thiamine mononitrate, a standard water-soluble form. The whole-product serving price works out to about $0.18 per 100 mg of thiamin.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The source is thiamine mononitrate, a standard water-soluble form. The evaluation found no configured sweetener or color flags in the available other-ingredient information.
Thiamin Chemical Form
The source is thiamine mononitrate, a standard water-soluble form of thiamin.
Excipient Purity
The evaluation found no configured sweetener or color flags in the available other-ingredient information.

Dose, Safety & Label Transparency100

A serving provides 50 mg of thiamin, with thiamine mononitrate identified as the source.
Thiamin Dosage Potency
A serving provides 50 mg of thiamin.
Label Transparency & Proprietary Blends
The thiamin amount is recorded as 50 mg per serving and thiamine mononitrate is identified as its source.

Value40

Based on the whole-product serving price, the cost is about $0.18 per 100 mg of thiamin.
Price per Declared Dose
Based on the whole-product serving price, the cost is about $0.18 per 100 mg of thiamin.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin