Cal/Mag/Vit D3 with Vitamin K2

Cal/Mag/Vit D3 with Vitamin K2

NaturesPlus4.6 (2,666 ratings)
Format:Tablet Quantity: 180 Tablet(s) · 45 servings
Goals
$31.41 $0.69 per serving

Product analysis

69 out of 100

Cal/Mag/Vit D3 with Vitamin K2 may help cover nutritional gaps that affect normal bone and muscle function.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality56

Magnesium uses a reasonably favourable form, while calcium and vitamin K have more moderate form profiles. The named vitamin D preparation does not by itself establish a further quality advantage.

Ingredient Transparency100

All four nutrient amounts and forms are disclosed. That makes the combination straightforward to compare with other mineral supplements.

Value For Money47

Calcium, magnesium and vitamin K offer middling value at the full serving cost. The separate value of vitamin D remains uncertain.

Customer Satisfaction84

Customer feedback is positive. Thousands of ratings provide a broad base for judging satisfaction.

Product Focus66

The formula centres on normal bone and mineral nutrition, chiefly when intake is low. The large calcium and magnesium amounts do not establish extra benefit, and the MK-4 form cannot be assumed to match MK-7 bone findings.

Format
Tablet
Container
180 Tablet(s)
Per serving
$0.69
Customer rating
4.6 · 2,666 ratings
Report analysis

Goals

Bone Health
Impact
Highest effect
B+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin K · 100 mcgMagnesium · 600 mgCalcium · 1200 mgVitamin D · 25 mcg
Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Everyday Health
Impact
Highest effect
B Ingredient FitB+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin D · 25 mcgMagnesium · 600 mgVitamin K · 100 mcg
Study evidence
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Cardiovascular Support
Impact
High effect
C+ Ingredient FitD+ PathwaysB EvidenceA+ Formulation Logic
Vitamin K · 100 mcgMagnesium · 600 mgVitamin D · 25 mcg
Study evidence
Magnesium Supportive 123 studies
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies
Fitness
Impact
Moderate effect
C+ Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Magnesium · 600 mgVitamin D · 25 mcg
Study evidence
Magnesium Disputed 29 studies
Vitamin D Disputed 163 studies
Heart Health
Impact
High effect
C+ Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Vitamin K · 100 mcgMagnesium · 600 mgVitamin D · 25 mcg
Study evidence
Magnesium Supportive 158 studies
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Testosterone Support
Impact
High effect
C Ingredient FitB- PathwaysB+ EvidenceA+ Formulation Logic
Magnesium · 600 mgVitamin D · 25 mcg
Study evidence
Magnesium Disputed 5 studies
Vitamin D Supportive 56 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
25 mcg
Vitamin K2 (Menatetrenone)
100 mcg 41
Calcium (Calcium Amino Acid Chelate)
1200 mg 48
Magnesium (Magnesium Amino Acid Chelate)
600 mg 61
Gluten Free Adults 18–50
Report overview
C+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD+ Value
Each serving provides 1200 mg of calcium, a substantial amount, at a fairly high cost per serving. It uses Calcium Amino Acid Chelate. A flow agent is listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability65

The calcium amount is clearly stated. It uses Calcium Amino Acid Chelate.
Calcium Form & Absorption Potential
It uses Calcium Amino Acid Chelate.
Elemental Calcium Transparency
The label states 1200 mg of elemental calcium per serving.

Dose, Safety & Label Transparency30

The serving provides 1200 mg of calcium; some may not be absorbed in a single serving. A flow agent is listed.
Absorption-Optimized Serving Dose
The serving provides 1200 mg of calcium; some may not be absorbed in a single serving.
Formulation Purity & Additives
A flow agent is listed.

Value50

The cost per serving is fairly high.
Price Per Serving Efficiency
The cost per serving is fairly high.
D Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyD+ Value
+3
Each serving provides 600 mg of magnesium at a moderate cost. The magnesium amount is high, and the chelation standard is unspecified. The source is Magnesium Amino Acid Chelate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability49

Magnesium Amino Acid Chelate is the magnesium source; the chelation standard is unspecified.
Magnesium Form & Absorption Potential
It uses Magnesium Amino Acid Chelate.
Patented Materials & Chelation Quality
The chelation standard is unspecified.

Dose, Safety & Label Transparency79

The serving states 600 mg of magnesium and 1200 mg of calcium.
Elemental Yield Transparency
600 mg of elemental magnesium per serving is stated along with its source.
Therapeutic Dosage Alignment
Each serving provides 600 mg of elemental magnesium.
Synergistic Formulation Logic
It also provides 1200 mg of calcium per serving. A qualifying supporting ingredient is present.

Value50

The serving cost is moderate.
Price Per Elemental Quality
The serving cost is moderate.
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyD+ Value
The serving provides 100 mcg of vitamin K2 as MK-4 at a moderately high cost. It does not identify an MK-7 source.
How this ingredient is rated

Active Ingredient Quality & Bioavailability33

It provides vitamin K2 as MK-4. No MK-7 source is identified.
Vitamin K Form (MK-7 vs. MK-4 vs. K1)
It provides vitamin K2 as MK-4.
MK-7 Isomer Disclosure
No MK-7 source is identified.

Dose, Safety & Label Transparency44

No MK-7 amount is stated, and no MK-7 source is identified. The amount and form are stated.
Vitamin K2 (MK-7) Dosage Efficacy
No MK-7 amount is stated, and no MK-7 source is identified.
Form and Subtype Transparency
The amount and MK-4 form are stated.

Value50

The cost per serving is moderately high.
Price per Effective MK-7 Serving
The cost per serving is moderately high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  7. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  8. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  9. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  10. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  11. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  12. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  13. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  14. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  15. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  16. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  17. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  20. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K