True Calm

True Calm

NOW4.6 (4,662 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals

Product analysis

61 out of 100

True Calm may offer some short-term calming support through GABA, though the findings come from narrow settings. Several other ingredients are present in amounts too small to add meaningful support.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality35

Niacin’s form is clearly identified, while several other forms and herbal preparations are unspecified. The quality of B6 and magnesium also remains uncertain despite their named forms.

Ingredient Transparency77

All listed amounts are disclosed, allowing serving comparisons. Most non-vitamin preparations and forms are not specified.

Value For Money58

GABA and the labeled valerian serving are economical, while glycine and taurine offer weaker value. The low serving cost does not establish that the small added ingredients provide a useful effect.

Customer Satisfaction86

Customer ratings are generally positive. A large number of ratings gives a broader picture of customer satisfaction.

Product Focus69

GABA provides the clearest link to short-term calming, with limited evidence for lasting relief. Several other ingredients contribute little at their stated amounts, keeping sleep and mood benefits more uncertain.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.12
Customer rating
4.6 · 4,662 ratings
Report analysis

Goals

Stress Relief
Impact
Highest effect
A- Ingredient FitD+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 6.5 mgGlycine · 200 mgGABA · 200 mgVitamin B6 · 8 mg

GABA supplies the main connection to calming in this formula. Its support comes from limited short-term task-stress findings, and food preparations and narrow settings do not establish lasting benefit from a supplement. The other relevant ingredients, including magnesium, valerian, glycine, taurine and B6, are present in amounts too small to add a meaningful contribution in the supplied comparison.

How this product is rated for Stress Relief

Ingredient fit89

GABA drives the stress connection; the smaller calming ingredients contribute little.
Goal fit
The relevant ingredients give the formula a clear connection to stress relief, though its uses extend to other goals.
Dose adequacy
The selected serving provides partial amounts for some relevant ingredients, limiting their contribution compared with the supplied references.

Pathways53

Calming is the only substantially covered role in the saved findings.
Depth
Neural calming is the strongest role in the saved findings; this indicates emphasis, not a measured benefit.
Breadth
Calming is the only substantially covered role in the saved findings.

Evidence91

GABA provides the leading supported contribution. Short-term findings do not establish lasting supplement benefits.
Evidence strength
GABA provides the leading supported contribution. Short-term findings do not establish lasting supplement benefits.
Studied preparation
The relevant preparations are recognized in the supplied comparison; that does not guarantee the same benefit in every setting.

Formulation logic100

The relevant ingredients can contribute independently or have the partners required by the supplied comparison. No conflict among the combinations evaluated was identified in the supplied findings.
Partner coverage
The relevant ingredients can contribute independently or have the partners required by the supplied comparison.
Conflicts
No conflict among the combinations evaluated was identified in the supplied findings.
Effective doses
GABA provides a meaningful amount; magnesium, valerian, glycine, taurine and B6 are too small to contribute here.
Study evidence
GABA Supportive 6 studies
Glycine Supportive 1 study
Magnesium Supportive 13 studies
Taurine Supportive 5 studies
Valerian Supportive 18 studies
Sleep Support
Impact
Moderate effect
C Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic
Magnesium · 6.5 mgGlycine · 200 mg

True Calm may offer modest support across calming and precursor pathways, with GABA and vitamin B6 contributing most to its sleep-related profile. The amounts of glycine, magnesium, valerian, and taurine are too small to add much here.

This blend does not include melatonin for a separate sleep-timing role. Inositol and niacin are also present, but their sleep contribution is not established in the supplied facts.

How this product is rated for Sleep Support

Ingredient fit62

GABA and vitamin B6 are the main credited ingredients; inositol and niacin are additional actives without a reviewed sleep role.
Goal fit
Each credited ingredient is treated as able to contribute alone or with its listed partner.
Dose adequacy
Only two ingredients make a meaningful sleep contribution; the other listed amounts are too small in this context.

Pathways16

The formula touches calming and precursor pathways, but neither reaches broad coverage across sleep routes.
Depth
Calming and precursor pathways are represented, but neither is developed broadly by the blend.
Breadth
No pathway reaches broad coverage, despite the formula touching more than one route.

Evidence58

GABA has limited sleep-specific support, and vitamin B6’s normal metabolic role does not establish a direct sleep benefit.
Evidence strength
The strongest sleep-specific basis remains limited for GABA, while B6’s role is not a direct sleep claim.
Studied preparation
The contributing GABA and B6 forms are identified well enough for the saved ingredient profiles.

Formulation logic100

The credited ingredients have recognized forms, though the product does not add a preparation with stronger sleep-specific support.
Partner coverage
The credited ingredients have the partners they need or are treated as able to act alone.
Conflicts
No listed ingredient is flagged as a sleep-related conflict.
Effective doses
Glycine, magnesium, valerian, and taurine fall below the contribution threshold at their labeled amounts.
Study evidence
GABA Supportive 4 studies
Glycine Supportive 3 studies
Magnesium Supportive 23 studies
Taurine Not classified

No linked studies yet.

Valerian Supportive 31 studies
Mood Support
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B6 · 8 mgMagnesium · 6.5 mg

Niacin and vitamin B6 can help address dietary shortfalls associated with depressed mood or irritability; extra mood benefit is not established when intake is adequate. GABA has limited, preparation-specific stress research that does not establish the same effects for generic oral GABA. The small magnesium amount contributes little to filling a dietary gap, while glycine and valerian research mainly concerns sleep or relaxation rather than direct mood outcomes.

How this product is rated for Mood Support

Ingredient fit78

The recognized ingredients relate to mood support, although the product may also serve other goals. The serving amounts fall short of several saved comparisons, limiting the amount-based findings without proving ineffectiveness.
Goal fit
The recognized ingredients relate to mood support, although the product may also serve other goals.
Dose adequacy
The serving amounts fall short of several saved comparisons, limiting the amount-based findings without proving ineffectiveness.

Pathways16

The strongest represented aspect is monoamine signalling, with limited representation from the recognized ingredients. No aspect reaches the saved coverage comparison; the ingredient roles remain limited rather than broadly established.
Depth
The strongest represented aspect is monoamine signalling, with limited representation from the recognized ingredients.
Breadth
No aspect reaches the saved coverage comparison; the ingredient roles remain limited rather than broadly established.

Evidence96

Vitamin B6 provides the strongest recognized evidence here, subject to its population and preparation limitations. The saved result recognizes the qualifying preparations as studied; this does not establish benefit for every user.
Evidence strength
Vitamin B6 provides the strongest recognized evidence here, subject to its population and preparation limitations.
Studied preparation
The saved result recognizes the qualifying preparations as studied; this does not establish benefit for every user.

Formulation logic100

The recognized ingredients have their required partners or can stand alone, and no listed conflict was matched. Their amounts meet the saved minimum comparisons.
Partner coverage
The recognized ingredients do not lack a required partner under the supplied checks; this does not demonstrate synergy.
Conflicts
No listed ingredient conflict was matched. This check does not establish medication compatibility.
Effective doses
All recognized ingredients meet the saved minimum amount comparison, which is not a proven clinical effect threshold.
Study evidence
GABA Supportive 12 studies
Glycine Mixed 3 studies
Magnesium Supportive 60 studies
Valerian Supportive 17 studies
Vitamin B6 Supportive 19 studies

Ingredients

IngredientAmount per servingScore
Niacin (Niacinamide)
45 mg 73
Vitamin B6 (Pyridoxine Hydrochloride)
8 mg
Magnesium (Magnesium Bisglycinate)
6.5 mg
GABA
200 mg 81
Glycine
200 mg 48
Taurine
200 mg 53
Inositol
100 mg
Valerian
25 mg 64
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
Each serving provides 45 mg of niacin as niacinamide, a form that generally does not cause flushing. The whole-product serving costs about $0.13.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin comes as niacinamide, a standard form of vitamin B3.
Niacin Form & Goal Alignment
Niacinamide is a standard vitamin B3 form used for general nutrition.
Precursor Source Quality
The saved facts identify standard niacinamide as the niacin source.

Dose, Safety & Label Transparency67

The niacin amount and niacinamide form are identified: 45 mg per serving.
Clarity of Chemical Form
The saved facts identify the niacin form as niacinamide.
Form-Specific Dosage Efficacy
Each serving provides 45 mg of niacin as niacinamide.
Flush Risk & Safety Labeling
Niacinamide generally does not cause the flushing associated with nicotinic acid; no no-flush claim is recorded in the saved facts.

Value60

The whole-product price is about $0.13 per serving.
Price Per Effective Serving
A whole-product serving costs about $0.13; that price includes the rest of the product, not just niacin.
GABA · 200 mg OverallScore81
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value
The serving provides 200 mg of GABA. The whole-product serving costs about $0.13, a low price for the assessed GABA source.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The saved information identifies generic GABA, while its production method is unresolved.
GABA Source & Production Method
The saved information identifies generic GABA, while its production method is unresolved.

Dose, Safety & Label Transparency82

The serving provides 200 mg of GABA. The saved ingredient information includes a flow agent.
GABA Dosage Adequacy & Transparency
The serving provides 200 mg of GABA.
Label Purity & Excipient Quality
The saved ingredient information includes a flow agent.

Value100

A whole-product serving costs about $0.13, a low serving price for the assessed GABA source.
Price per Effective Dose
A whole-product serving costs about $0.13, a low serving price for the assessed GABA source.
Glycine · 200 mg OverallScore48
C Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value
Each serving lists 200 mg of glycine, a relatively small amount. The whole-product price works out to about $0.64 per gram of glycine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

The available facts include a GMP manufacturing claim for the glycine, but do not establish a specific purity grade or certification.
Glycine Sourcing and Purity Standards
The available facts include a GMP manufacturing claim for the glycine, but do not establish a specific purity grade or certification.

Dose, Safety & Label Transparency46

Each serving lists 200 mg of glycine, a relatively small amount. Ordinary excipients or capsule materials are recorded; that alone does not establish a minimal ingredient list.
Clinically Relevant Dosage
The serving provides 200 mg of glycine, a relatively small amount.
Label Transparency and Yield Disclosure
The glycine amount is explicitly listed as 200 mg per serving.
Clean Label and Excipient Quality
Ordinary excipients or capsule materials are recorded; that alone does not establish a minimal ingredient list.

Value30

Using the whole-product price, the cost works out to about $0.64 per gram of glycine.
Cost Efficiency per 1,000mg of Glycine
About $0.64 per gram of glycine, based on the whole-product price, is relatively costly on this measure.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  2. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  3. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  4. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  5. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  6. [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
    Strzelecki D; Kropiwnicki P; Rabe-Jabłońska J · Psychiatria polska · 2014
    Single-arm trial29 participantsMood Support forGlycine
  7. Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
    Pålsson E; Jakobsson J; Södersten K; Fujita Y; Sellgren C; Ekman CJ; Ågren H; Hashimoto K; Landén M · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2015
    Cross-sectional study327 participantsMood Support forGlycine
  8. Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
    Peselow ED; Deutsch SI; Stanley M; Banay-Schwartz M; Virgilio J; Fieve RR · Psychopharmacology · 1983
    Cross-sectional study27 participantsMood Support forGlycine
  9. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  10. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  11. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  12. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  13. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  14. Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study.
    Chandra Shekhar H; Joshua L; Thomas JV · Advances in therapy · 2024
    Randomized trial80 participantsMood Support Sleep Support Stress Relief forValerian
  15. Chemotypic diversity and neuroactive potential of Valeriana jatamansi Jones: a systematic review on phytochemistry, pharmacology and standardisation challenges.
    Nisar S; Jan N; Hassan I; Andleeb L; Shabir PA · Natural product research · 2026
    Meta-analysis12 studies pooledMood Support forValerian
  16. Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis.
    Shinjyo N; Waddell G; Green J · Journal of evidence-based integrative medicine · 2021
    Meta-analysis6,894 participants60 studies pooledMood Support forValerian
  17. Assessment of Valeriana officinalis l. (Valerian) for Conscious Sedation of Patients During the Extraction of Impacted Mandibular Third Molars: A Randomized, Split-Mouth, Double-Blind, Crossover Study.
    Farah GJ; Ferreira GZ; Danieletto-Zanna CF; Luppi CR; Jacomacci WP · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2020
    Randomized trial20 participantsMood Support forValerian
  18. Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review.
    Araújo JO; Bergamaschi CC; Lopes LC; Guimarães CC; de Andrade NK; Ramacciato JC; Motta RHL · BMJ open · 2021
    Systematic review327 participants12 studies pooledMood Support Stress Relief forValerian
  19. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  20. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support Stress Relief forVitamin B6