Coenzyme B-Complex Caps

Coenzyme B-Complex Caps

Country Life4.9 (36,989 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 60 servings
Goals

Product analysis

66 out of 100

Coenzyme B-Complex Caps supports normal energy use and blood formation when B-vitamin intake is low. Most forms are identified, but missing mixture proportions make close comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality63

Several B vitamins have clearly identified forms that the body can use. Missing mixture proportions and limited information on other ingredients prevent a more definite comparison.

Ingredient Transparency73

All amounts and most preparations are stated. Several mixtures lack proportions, and PABA, inositol and alpha lipoic acid have no named form.

Value For Money46

Vitamin B6 and riboflavin compare favorably on price. The serving looks expensive for niacin, vitamin B5 and choline, while several other comparisons remain uncertain.

Customer Satisfaction96

Customer feedback is very positive across a particularly large review history. The breadth of feedback describes satisfaction without proving extra benefits from coenzyme forms.

Product Focus61

The main benefits concern meeting B-vitamin needs across energy, blood formation and normal brain function. Extra nutrients and coenzyme forms do not establish better mood, thinking or work output when intake is adequate.

Format
Capsule
Container
120 Capsule(s)
Per serving
$0.43
Customer rating
4.9 · 36,989 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 500 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 500 mcg
Study evidence
Folate Supportive 80 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 200 mcgNiacin · 100 mgVitamin B12 · 500 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Hair Health
Impact
High effect
B+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Biotin · 200 mcg
Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per servingScore
Thiamin (Thiamine Cocarboxylase Chloride, Thiamine Hydrochloride)
50 mg 76
Riboflavin (Riboflavin 5-Phosphate)
50 mg 84
Niacin (Inositol Hexanicotinate)
100 mg 57
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Alpha-Ketoglutarate Hydrochloride, Pyridoxine Hydrochloride)
50 mg 74
Folate (L-5-Methyltetrahydrofolate)
667 mcg DFE
Vitamin B12 (Dibencozide, Methylcobalamin)
500 mcg 70
Biotin (D-Biotin)
200 mcg
Pantothenic Acid (Calcium D-Pantothenate, Pantethine)
50 mg 70
Choline (Choline Bitartrate)
55 mg 55
PABA
50 mg 78
Inositol
27 mg
Alpha-Lipoic Acid
100 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
Each serving provides 500 mcg of B12 at a high cost for the amount provided. It combines adenosylcobalamin and methylcobalamin, but their individual amounts are unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It combines adenosylcobalamin and methylcobalamin, but their individual amounts are unknown.
Bioactive B12 Form Selection
It combines adenosylcobalamin and methylcobalamin, but their individual amounts are unknown.

Dose, Safety & Label Transparency64

Each serving provides 500 mcg of vitamin B12. The total amount is stated, but the amount of each form is unknown.
Therapeutic Dosage Level
Each serving provides 500 mcg of vitamin B12.
Label and Form Transparency
The total amount is stated, but the amount of each form is unknown.

Value20

The cost is high for the amount of B12 provided. The individual form proportions are unknown.
Price per 1,000 mcg B12
The cost is high for the amount of B12 provided. The individual form proportions are unknown.
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Coenzyme B-Complex Caps provides 50 mg of riboflavin per serving at a moderate cost per serving. It combines standard riboflavin and riboflavin 5-phosphate, but their proportions aren't disclosed. The available Other Ingredients list names no artificial colors, flavors or synthetic sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

It combines standard riboflavin and riboflavin 5-phosphate, but their proportions aren't disclosed.
Riboflavin Form Quality
It combines standard riboflavin and riboflavin 5-phosphate, but their proportions aren't disclosed.

Dose, Safety & Label Transparency100

Each serving provides 50 mg of riboflavin. The available Other Ingredients list names no artificial colors, flavors or synthetic sweeteners.
Dosage for Energy & Metabolism
Each serving provides 50 mg of riboflavin, a high amount.
R5P Elemental Yield Transparency
The total riboflavin amount is stated, although the shares from each form are unknown.
Additive Purity
The available Other Ingredients list names no artificial colors, flavors or synthetic sweeteners.

Value80

The cost per serving is moderate.
Price per Serving Value
The cost per serving is moderate.
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
Each serving provides 50 mg of thiamin, but the cost relative to that amount is high. It combines thiamine cocarboxylase chloride and thiamine hydrochloride in unknown proportions. The listed amount is clear.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

It uses thiamine cocarboxylase chloride and thiamine hydrochloride, but their proportions are unknown. No configured artificial colors or sweeteners are listed.
Thiamin Chemical Form
It uses thiamine cocarboxylase chloride and thiamine hydrochloride, but their proportions are unknown.
Excipient Purity
No configured artificial colors or sweeteners are listed.

Dose, Safety & Label Transparency100

Each serving supplies 50 mg of thiamin. The amount is clearly stated.
Thiamin Dosage Potency
Each serving supplies 50 mg of thiamin.
Label Transparency & Proprietary Blends
The label states the thiamin amount and source.

Value40

The cost is high relative to the declared thiamin amount; the full serving price may overstate the cost attributable to thiamin.
Price per Declared Dose
The cost is high relative to the declared thiamin amount; the full serving price may overstate the cost attributable to thiamin.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate