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Vitamin D-3 5000 IU

Source Naturals
4.8
★ ★ ★ ★ ★
(3430 ratings)
Vitamin D 5000 IU
Product Image
Score82
A focused, economical D3 capsule provides a high 5,000 IU serving. The amount needs a clear reason and attention to total intake rather than automatic long-term daily use.
How scoring works
Quantity:240 Capsule(s) • (240 servings)
Goals:
General Health
Testosterone Support
Anti-Inflammatory Support
Anti-Aging
Immunity
Energy

Score 82

A focused, economical D3 capsule provides a high 5,000 IU serving. The amount needs a clear reason and attention to total intake rather than automatic long-term daily use.
How scoring works
$16.67($0.06 per serving)
iHerb
$ 17.85
Vitacost
$ 16.67
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Analysis

The formula provides only vitamin D3, keeping its purpose and amount easy to understand. A 5,000 IU serving can be useful in a targeted plan but is higher than many adults need every day.

No oil carrier or raw D3 source is disclosed. Taking the capsule with a fat-containing meal may support absorption, while source-conscious shoppers may want more traceability.

A large serving count and low per-serving burden create strong practical value. It fits adults using a clinician-guided or lab-informed higher-dose plan, not users simply looking for a default maintenance supplement.

Who is it for
  • Adults with a documented need for higher-dose D3
  • Users following a monitored vitamin D plan
  • People who prefer a simple one-active capsule
Best for
  • Targeted higher-dose vitamin D use
  • One-capsule convenience
  • Long-supply value

Pros

  • Uses vitamin D3
  • Clearly states a 5,000 IU amount
  • Contains no distracting active blend
  • Offers a large number of servings

Cons

  • The dose is high for routine unsupervised maintenance
  • No oil carrier is listed
  • The raw D3 source and complete excipients are not supplied

Warnings

  • Daily 5,000 IU use exceeds the common adult upper intake level and is best guided by measured need
  • Combining it with other D3 products can raise total intake enough to increase excessive-calcium risk
  • People with high calcium levels or disorders that increase vitamin D sensitivity need medical supervision

Nutrient quality

78 High impact

Cholecalciferol is a suitable form and the amount has clear potency. The aggressive daily dose reduces balance for routine unsupervised maintenance.

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Ingredient transparency

81 Highest impact

The active form and amount are fully clear without a hidden blend. Missing intake guidance and capsule ingredients prevent complete label transparency.

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Customer satisfaction

72 High impact

The aggregate satisfaction signal is exceptionally strong and supported by extensive volume. Missing review details prevent assessment of tolerance or ease of use.

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Value for money

98 Highest impact

High potency and a large supply create excellent value for users with a confirmed need. The aggressive amount reduces general category suitability despite strong economics.

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Report analysis

Goals

General Health
Impact
Highest effect
A+ Goal FitB Strength of SupportC CoverageA Formula Quality
Vitamin D · 5000 IU

Vitamin D3 supports foundational bone, immune, and muscle functions. The single vitamin influences bone, immune, and muscle pathways but does not fill multiple nutrient gaps.

The 5,000 IU vitamin D3 dose reaches the upper end of the preferred daily range. Cholecalciferol is the preferred D3 form and its amount is clear, but no oil carrier or raw source is disclosed.

Study evidence
Vitamin D Supportive 115 studies
Testosterone Support
Impact
Highest effect
A- Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Vitamin D · 5000 IU

Vitamin D3 provides a foundational nutrient involved in normal endocrine function. The high amount may be most relevant when deficiency has been confirmed.

Cholecalciferol is the preferred clearly disclosed form. Long-term daily use at 5000 IU can raise calcium too far in some users without monitoring.

Study evidence
Vitamin D Supportive 56 studies
Anti-Inflammatory Support
Impact
High effect
A- Goal FitB+ Strength of SupportD+ CoverageA Formula Quality
Vitamin D · 5000 IU

Vitamin D3 provides direct immune-regulating support relevant to inflammatory balance. The 5,000 IU serving reaches the upper end of common daily supplemental use.

The capsule lacks a stated oil carrier and raw vitamin source, so delivery quality cannot be fully judged. Prolonged use at this amount can raise calcium levels in susceptible users and is best guided by vitamin D testing.

Study evidence
Vitamin D Supportive 101 studies
Anti-Aging
Impact
High effect
B+ Goal FitC+ Strength of SupportB- CoverageA Formula Quality
Vitamin D · 5000 IU

Vitamin D3 supports bone, muscle, and immune functions that are important for healthy aging. It remains a foundational nutrient rather than a direct intervention for mitochondrial decline or other specialized aging pathways.

The 5,000 IU amount is potent but exceeds the common adult daily upper limit, so long-term use without confirming blood levels may increase the risk of excess calcium. Cholecalciferol is appropriate, while the capsule lacks a disclosed oil carrier or raw-source detail.

Study evidence
Vitamin D Supportive 50 studies
Immunity
Impact
High effect
A Goal FitB- Strength of SupportD CoverageA Formula Quality
Vitamin D · 5000 IU

The capsule provides 5,000 IU of vitamin D3, a direct regulator of immune signaling and barrier function. Cholecalciferol is a suitable form, and the amount may be useful for people with documented higher needs.

The dose sits at the upper end of routine supplementation and is less appropriate for indefinite use without knowing vitamin D status. No oil carrier is disclosed, which may make absorption more dependent on taking it with a fat-containing meal.

Study evidence
Vitamin D Supportive 85 studies
Energy
Impact
High effect
C Goal FitB Strength of SupportD CoverageA- Formula Quality
Vitamin D · 5000 IU

Vitamin D3 may improve fatigue and muscle function when low vitamin D is part of the problem. The substantial cholecalciferol serving gives this focused formula a plausible role in restoring low status, but it is not a broad or immediate energy formula.

Coverage is limited to one foundational pathway and does not include alertness, metabolic B vitamins, or stress support. Because 5,000 IU is a high daily amount, long-term use is best matched to measured vitamin D status to reduce the risk of excessive calcium levels.

Study evidence
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Cholecalciferol)
5000 IU
Gluten Free Adults 18–50 Dairy Free
Report overview
B- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

The 5,000 IU vitamin D3 dose reaches the upper end of the preferred daily range. The capsule lacks a listed oil carrier, and the raw vitamin source is not disclosed. Cost efficiency is excellent, though qualifying independent verification is not shown.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  2. Effects of Vitamin D3 Supplementation on Muscle Strength, Mass, and Physical Performance in Women with Vitamin D Insufficiency: A Randomized Placebo-Controlled Trial.
    Bislev LS; Langagergaard Rødbro L; Rolighed L; Sikjaer T; Rejnmark L · Calcified tissue international · 2019
    Randomized trial81 participantsGeneral Health forVitamin D
  3. Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline.
    Demay MB; Pittas AG; Bikle DD; Diab DL; Kiely ME; Lazaretti-Castro M; Lips P; Mitchell DM; Murad MH; Powers S; Rao SD; Scragg R; Tayek JA; Valent AM; Walsh JME; McCartney CR · The Journal of clinical endocrinology and metabolism · 2024
    Guideline / consensusGeneral Health forVitamin D
  4. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  5. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  6. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  7. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  8. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  9. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  10. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  11. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  12. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  13. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  14. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  15. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  16. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  17. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  18. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  19. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  20. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  21. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  22. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  23. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  24. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  25. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  26. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  27. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  28. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  29. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  30. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  31. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  32. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D