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Skin Nails & Hair 2

MegaFood
4.7
★ ★ ★ ★ ★
(1486 ratings)
Vitamin B5 20 mg
Biotin 300 mcg
Stinging Nettle 500 mg
Product Image
Score76
A well-formed beauty-nutrition product with useful zinc and antioxidants. Its stated goals do not match the formula well, and nettle quality remains unclear.
How scoring works
Quantity:60 Tablet(s) • (30 servings)
Goals:
Anti-Inflammatory Support
Testosterone Support

Score 76

A well-formed beauty-nutrition product with useful zinc and antioxidants. Its stated goals do not match the formula well, and nettle quality remains unclear.
How scoring works
$25.99($0.86 per serving)
Pure Formulas
$ 25.99
iHerb
$ 25.99
Vitacost
$ 27.45
Walmart
$ 25.99
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Analysis

Vitamin C, natural vitamin E, active B6, zinc bisglycinate, selenium, biotin, and B5 provide a coherent beauty-nutrition base. The ingredient forms are generally thoughtful and clearly disclosed.

Biotin is modest for targeted hair and nail use, and the label does not verify the active d-isomer. Nettle is present at 500 mg but lacks plant-part and preparation details, making its potency hard to judge.

The formula makes more sense for hair, skin, and nails than for testosterone or broad inflammatory support. Users buying for the stated goals may find the pathway coverage poorly aligned.

Who is it for
  • Adults seeking broad hair, skin, and nail nutrients
  • Users who value active B6 and chelated zinc
  • People comfortable taking two tablets
Best for
  • Beauty-focused micronutrient coverage
  • Zinc and antioxidant intake
  • Nettle-containing hair formulas

Pros

  • Uses P5P vitamin B6
  • Provides zinc bisglycinate
  • Includes natural vitamin E
  • Substantial nettle weight

Cons

  • Poor fit for stated testosterone goal
  • Biotin amount is modest for targeted use
  • Nettle plant part is undisclosed
  • Above-midpoint cost for nettle quality

Warnings

  • Biotin can interfere with some laboratory tests; tell the testing clinician before blood work
  • Nettle may affect diuretic, blood pressure, or blood sugar medicines
  • The nettle plant part and preparation are not supplied, limiting suitability review

Nutrient quality

87 Highest impact

Active vitamin B6, natural vitamin E, chelated zinc, and fermented selenium provide strong form quality. Nettle is substantial but incompletely characterized, while the formula remains focused and balanced.

Ingredient transparency

76 High impact

All active amounts are stated without a proprietary blend. Nettle plant part and preparation, complete directions, and non-active tablet ingredients remain missing.

Customer satisfaction

71 High impact

The supplied satisfaction metric is strong and response volume is large. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

68 High impact

Favorable forms and focused dosing partly justify the elevated serving cost. The product is reasonably competitive, though simpler beauty formulas may cost less.

Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C- Goal FitB Strength of SupportC+ CoverageB- Formula Quality
Vitamin E · 20 mgVitamin C · 200 mg

Vitamins C and E, zinc, selenium, and nettle create a broad antioxidant and immunomodulatory foundation. The formula may support inflammatory balance, but its main design remains skin, hair, and nail nutrition rather than targeted systemic inflammation.

The 500 mg nettle amount is substantial, yet plant part and preparation are missing, which prevents active-potency assessment. Biotin and pantothenic acid add little direct anti-inflammatory value and broaden the label without strengthening the main goal.

Study evidence
Selenium Supportive 34 studies
Stinging Nettle Supportive 5 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C- Goal FitC+ Strength of SupportD+ CoverageD+ Formula Quality
Zinc · 15 mg

Zinc bisglycinate at 15 mg supplies a well-absorbed foundational mineral, while 500 mg nettle may have some relevance to free-hormone pathways. Nettle plant part and preparation are not stated, so testosterone-specific activity cannot be judged.

Active vitamin B6 adds modest endocrine support, but most vitamins target skin, hair, and nails rather than hormones. The formula lacks vitamin D, boron, ashwagandha, or another well-defined stress or endocrine active.

Study evidence
Zinc Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 600 mcg RAE
Vitamin C (Ascorbic Acid)
 200 mg
Vitamin E (D-Alpha-Tocopherol)
 20 mg
Vitamin B6 (Pyridoxal-5-Phosphate)
 4 mg
Biotin
300 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 20 mg
Zinc (Zinc Bisglycinate)
 15 mg
Selenium (fermented Selenium Glycinate)
 50 mcg
Nettle (Urtica dioica)
 500 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Vitamin B5 (Calcium D-Pantothenate) · 20 mg OverallScore60
A- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Calcium D-pantothenate provides a stable, well-absorbed vitamin B5 source. 20 mg per serving provides only basic support. Value is poor when the broader skin, nail, and hair formula is judged by vitamin B5 delivery alone.

View ingredientView products
Biotin · 300 mcg OverallScore56
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The label lists biotin without verifying the biologically active d-isomer. The 300 mcg dose is below the range used for targeted hair and nail support. The tablet format has acceptable purity, while the broader formula receives neutral value treatment.

View ingredientView products
Stinging Nettle (Urtica dioica) · 500 mg OverallScore38
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

The nettle source lacks both plant-part and preparation details. A 500 mg amount is substantial, but the unknown form leaves its potency uncertain. The above-median cost weakens value for such limited disclosure.

View ingredientView products
Loading alternative details
75 Performance

Skin Nails & Hair 2

MegaFood
<p>Nettle, zinc, biotin, active vitamin B6, natural vitamin E, and vitamin C closely match the original’s beauty-focused ingredient pattern. Duplicate form entries create some uncertainty, but the candidate keeps the same coherent nutrient and botanical core at a lower serving cost.</p>
71 Performance

Hairfluence

ZHOU
<p>MSM, collagen, keratin, vitamin C, and biotin broaden the structural hair-support concept beyond the original’s micronutrients and nettle. The structural ingredients are modest and vitamin A is fairly aggressive, so the broader label does not guarantee greater practical benefit.</p>
72 Performance

Hair Volume

New Nordic
<p>Biotin, apple procyanidins, zinc, copper, horsetail, and methionine create a directly hair-focused alternative with more varied structural support. Zinc oxide and copper sulfate are basic forms, and concentrated biotin can interfere with laboratory tests.</p>
77 Budget

Vitamin B Complex

California Gold Nutrition
<p>Active riboflavin and vitamin B6, pantothenic acid, folate, and biotin provide broad B-vitamin coverage at a much lower serving cost. Duplicate nutrient entries cloud totals, and the formula omits the original’s zinc, selenium, vitamin C, vitamin E, and nettle.</p>
71 Budget

B Complex

NATURELO Premium Supplements
<p>Active vitamin B6, methylfolate, methylcobalamin, biotin, and moderate B vitamins provide a balanced base at a much lower serving cost. The hidden produce blend adds little, while the lack of nettle, zinc, selenium, and antioxidant vitamins makes it less beauty-focused than the original.</p>
69 Budget

Liquid Collagen Complex Healthy Hair Skin & Nails Delicious Grape Flavor

RejuviCare
<p>Biotin and pantothenic acid preserve two key beauty nutrients at a much lower serving cost. The collagen amount is too small for much structural depth and the formula omits the original’s well-chosen zinc, selenium, antioxidant vitamins, and nettle.</p>
79 Value

Sublingual Liquid B-12 2000 mcg with B-Complex

Solgar
<p>A broad liquid B-complex supplies active riboflavin plus biotin and pantothenic acid at a much lower serving cost. Cyanocobalamin, pyridoxine, and unspecified folate or biotin forms limit quality, while the original’s minerals and nettle are absent.</p>
79 Value

Respir-All

NOW
<p>Quercetin, nettle, bromelain, buffered vitamin C, and zinc retain the original’s nettle and antioxidant themes at a slightly lower serving cost. The formula is aimed more at seasonal support than beauty, and vitamin B6 plus licorice warrant caution with long-term use.</p>
67 Value

Raw B-Complex

Garden of Life Vitamin Code
<p>A complete B-vitamin profile with methylcobalamin provides biotin and pantothenic acid at a lower serving cost. Unspecified forms and opaque fruit, vegetable, probiotic, and enzyme blends weaken transparency, but the daily nutrient coverage remains economical.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium and the course of mild Graves' orbitopathy.
    Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
    Randomized trial159 participantsAnti-Inflammatory Support forSelenium
  2. Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
    Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
    Randomized trial70 participantsAnti-Inflammatory Support forSelenium
  3. Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
    Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
    Randomized trial60 participantsAnti-Inflammatory Support forSelenium
  4. The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
    Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
    Meta-analysis656 participants11 studies pooledAnti-Inflammatory Support forSelenium
  5. Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
    Randomized trial33 participantsAnti-Inflammatory Support forSelenium
  6. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  7. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  8. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  9. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  10. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  11. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  12. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  13. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  14. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  15. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  16. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  17. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  18. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  19. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  20. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  21. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  22. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  23. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  24. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  25. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc