Product Image

Raw B-Complex

Garden of Life Vitamin Code
4.8
★ ★ ★ ★ ★
(11842 ratings)
Niacin 45 mg
Biotin 325 mcg
Vitamin B12 133 mcg
Riboflavin 10 mg
Vitamin B5 45 mg
Folate 450 mcg
Product Image
Score67

A moderate B complex with methylcobalamin and fewer extreme doses. Opaque produce, probiotic, and enzyme blends are the main weakness.

How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Energy
Heart Health
General Health
Metabolism Boost

Score 67

A moderate B complex with methylcobalamin and fewer extreme doses. Opaque produce, probiotic, and enzyme blends are the main weakness.

How scoring works

Also available as

1 option
120 servings 2 Capsule(s) • 120 Capsule(s) • 60 servings $28.69 ($0.47 per serving)
$16.79($0.55 per serving)
iHerb
$ 16.79
Vitacost
$ 17.59
Pure Formulas
$ 16.79
Walmart
$ 18.42
Report prices

Analysis

The two-capsule serving provides moderate amounts of thiamine, riboflavin, niacin, vitamin B6, folate, methylcobalamin, biotin, and pantothenic acid. The 10 mg vitamin B6 amount is more restrained than many B-100 formulas.

A 360 mg fruit and vegetable blend and 60 mg probiotic and enzyme blend do not disclose their individual ingredients or doses. Their added benefits, tolerance, and relevance therefore cannot be judged well.

The product suits users who value moderate B-vitamin dosing and a food-based positioning. It is less suitable for people who require exact blend disclosure, allergy screening, or strong practical value.

Who is it for
  • Adults wanting moderate B-vitamin amounts
  • People seeking methylcobalamin
  • Users comfortable with proprietary food and probiotic blends
Best for
  • General B-vitamin coverage
  • Normal energy metabolism
  • Moderate-dose daily use

Pros

  • Moderate vitamin B6 amount
  • Uses methylcobalamin
  • Broad B-vitamin base
  • Avoids B-100-level dosing

Cons

  • Two opaque proprietary blends
  • Individual probiotic and enzyme amounts are absent
  • Requires two capsules
  • Weak practical value

Warnings

  • The probiotic and enzyme blend may not suit every digestive tolerance
  • Opaque blends make allergy and sensitivity screening harder
  • The 45 mg niacin amount may cause discomfort in sensitive users depending on its form

Nutrient quality

73 High impact

Broad B-vitamin coverage and methylcobalamin provide a useful nutritional base without extreme dosing. Unspecified forms and low-potency secondary blends limit quality and measurable depth.

Ingredient transparency

60 Moderate impact

The B vitamins have separate amounts, but several chemical forms are not identified. Fruit, vegetable, probiotic, and enzyme blends hide component doses and probiotic viability.

Customer satisfaction

78 High impact

The exceptional average rating is supported by an exceptionally large review base. No review excerpts describe tolerance, effectiveness, or repeated complaints, so those experiences remain uncertain.

Value for money

59 Moderate impact

Broad B-vitamin coverage provides reasonable value, but the formula charges a premium for opaque secondary blends. Unspecified vitamin forms also make quality less certain than the marketing suggests.

Report analysis

Goals

Energy
Essential Energy Nutrients
Energy
Impact
High effect
A- Goal FitB Strength of SupportC CoverageB Formula Quality
Vitamin B5 · 45 mgRiboflavin · 10 mgThiamin · 5 mgVitamin B12 · 133 mcg

A broad B-vitamin profile supports the enzymes that convert food into usable cellular energy. Methylcobalamin improves B12 form quality, but its amount remains below the stated focused energy target.

The formula provides strong metabolic coverage without an alertness or adaptogen pathway. Fruit, vegetable, probiotic, and enzyme blends add little measurable energy support.

Study evidence
Vitamin B12 Disputed 14 studies
Heart Health
Heart Health
Impact
High effect
B Goal FitB+ Strength of SupportB- CoverageB- Formula Quality
Vitamin B12 · 133 mcgVitamin B6 · 10 mgFolate · 450 mcg

B vitamins and folate support homocysteine metabolism and cellular energy, giving the formula some cardiovascular relevance. Methylcobalamin is a favorable B12 form and the vitamin amounts are clearly stated.

The folate form is not identified and the added fruit, vegetable, probiotic, and enzyme blends are underdisclosed. The formula lacks stronger heart-focused actives such as magnesium, omega-3 fats, coenzyme Q10, or vitamin K2.

Study evidence
Folate Supportive 116 studies
Vitamin B12 No effect 42 studies
General Health
General Health
Impact
High effect
B+ Goal FitB Strength of SupportB- CoverageB Formula Quality
Folate · 450 mcgVitamin B12 · 133 mcg

The complete B-complex is well suited to supporting energy metabolism and other linked nutrient pathways. Methylcobalamin and substantial amounts across the B-vitamin family provide useful depth.

The folate compound and several other vitamin forms are not specified, which leaves some uncertainty about form quality. Added produce, probiotic, and enzyme blends are secondary because their individual contributions are not disclosed.

Study evidence
Folate Supportive 80 studies
Vitamin B12 Adverse 66 studies
Metabolism Boost
Metabolic B-Vitamins
Metabolism Boost
Impact
High effect
C+ Goal FitC+ Strength of SupportC CoverageB- Formula Quality
Biotin · 325 mcgNiacin · 45 mgVitamin B12 · 133 mcgRiboflavin · 10 mgThiamin · 5 mgVitamin B5 · 45 mgVitamin B6 · 10 mg

A complete B-vitamin base supports carbohydrate, fat, and amino-acid metabolism. These nutrients are foundational for energy production but do not directly increase metabolic rate when status is already adequate.

Methylcobalamin is favorable, while several other vitamin forms are not specified. Fruit, vegetable, probiotic, and enzyme blends add general-health content without much direct metabolic value.

Study evidence
Vitamin B12 Supportive 10 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
C+ Goal FitC Strength of SupportC- CoverageB- Formula Quality
Vitamin B12 · 133 mcgVitamin B6 · 10 mgFolate · 450 mcgNiacin · 45 mg

B6, folate, and methylcobalamin form a coherent nutrient pathway for homocysteine metabolism. The formula also contains niacin, but its unspecified form and modest amount do not support a targeted lipid effect.

Relevant B vitamins are clearly dosed, while folate form is not identified and B12 is oriented toward maintenance. Fruit, vegetable, probiotic, and enzyme blends add breadth without clear cardiovascular potency.

Study evidence
Folate Supportive 93 studies
Niacin Supportive 136 studies
Vitamin B12 No effect 33 studies
Hair Health
Hair Health
Impact
Moderate effect
D Goal FitB- Strength of SupportC- CoverageC- Formula Quality
Biotin · 325 mcg

B vitamins support normal cell turnover and energy metabolism and may help hair when a deficiency exists. The formula supplies many B vitamins but lacks iron, zinc, protein building blocks, or direct follicle support.

A fruit-and-vegetable blend plus a probiotic-and-enzyme blend adds breadth without clear hair evidence or individual dose disclosure. High-dose niacin and B vitamins may cause digestive discomfort, particularly on an empty stomach.

Study evidence
Biotin Supportive 4 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per serving
Thiamine (Vitamin B1)
 5 mg
Riboflavin (Vitamin B2)
 10 mg
Niacin
45 mg
Vitamin B6
10 mg
Folate
450 mcg
Vitamin B12 (Methylcobalamin)
 133 mcg
Biotin
325 mcg
Pantothenic Acid
45 mg
Raw Organic Fruit & Vegetable Blend
360 mg
Raw Probiotic & Enzyme Blend
60 mg
Gluten Free Adults 18–50 Vegan Kosher Vegetarian
Report overview
Niacin · 45 mg OverallScore62
C Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value

The niacin amount is suitable for a B-complex, but its chemical form is not disclosed. Capsule delivery is practical, although no specialized release or precursor technology is identified. The broader vitamin, fruit-and-vegetable, probiotic, and enzyme profile adds value while leaving niacin-specific quality uncertain.

View ingredientView products
Biotin · 325 mcg OverallScore59
B+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The modest biotin dose is unlikely to offer the targeted intake commonly sought for visible hair and nail support. The clearly disclosed amount and vegan capsule format are useful strengths, while the broader B-complex formula provides several additional nutrients. Value for biotin alone is limited, although judging the formula only by biotin would overlook those added B vitamins and blends.

View ingredientView products
Vitamin B12 (Methylcobalamin) · 133 mcg OverallScore54
A- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Methylcobalamin supplies a bioactive form, while the 133 mcg amount is geared mainly to maintenance. The capsule uses conventional oral delivery rather than a format specifically designed for absorption difficulties. Cost efficiency is weak for the B12 delivered, even after allowing for the bioactive form.

View ingredientView products
Loading alternative details
85 Performance

B-Complex Plus

Pure Encapsulations
<p>Its label clearly provides 100 mg of Thiamine as Thiamine Hydrochloride, making it a more clearly defined vitamin b12 and niacin and biotin and riboflavin and vitamin b5 option. Compared with the original, its ingredient and goal alignment is stronger, although it does not retain the original product’s folate coverage.</p>
81 Performance

Fully Active B Complex with Quatrefolic

Doctor's Best
<p>Its label clearly provides 40 mg of Vitamin C as Ascorbic Acid, making it a more clearly defined vitamin b12 and niacin and folate and biotin and riboflavin and vitamin b5 option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
75 Performance

B-Complex

Paradise Earth's Blend
<p>Its label clearly provides 10 mg of Vitamin B-1 as Benfotiamine, making it a more clearly defined vitamin b12 and niacin and folate and biotin and riboflavin and vitamin b5 option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
83 Budget

High Potency Vitamin B Complex

Lake Avenue Nutrition
<p>Its label clearly provides 110 mg of Thiamine Hydrochloride, preserving relevant vitamin b12 and niacin and biotin and riboflavin and vitamin b5 coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s folate coverage.</p>
84 Budget

Super B-Complex with Folic Acid plus Vitamin C

Nature's Bounty
<p>Its label clearly provides 60 mg of Vitamin C as Ascorbic Acid, preserving relevant vitamin b12 and niacin and biotin and riboflavin coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s folate and vitamin b5 coverage.</p>
83 Budget

Multi-B Benfotiamine 150 mg

BenfoComplete.com
<p>Its label clearly provides 150 mg of Benfotiamine, preserving relevant vitamin b12 and folate and riboflavin and vitamin b5 coverage. Compared with the original, it lowers the serving cost, although it does not retain the original product’s niacin and biotin coverage.</p>
82 Value

High Potency Vitamin B Complex

Lake Avenue Nutrition
<p>Its label clearly provides 10 mg of Vitamin B6 as Pyridoxal 5-Phosphate, keeping the formula relevant to vitamin b12 and niacin and biotin and riboflavin and vitamin b5. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s folate coverage.</p>
79 Value

Sublingual Liquid B-12 2000 mcg with B-Complex

Solgar
<p>Its label clearly provides 4 mg of Vitamin B1 as Thiamine Hydrochloride, keeping the formula relevant to vitamin b12 and biotin and vitamin b5. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s niacin and folate and riboflavin coverage.</p>
81 Value

B-Complex with Folic Acid plus Vitamin C

Nature's Bounty
<p>Its label clearly provides 120 mg of Vitamin C as Ascorbic Acid, keeping the formula relevant to vitamin b12 and niacin and biotin. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although it does not retain the original product’s folate and riboflavin and vitamin b5 coverage.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  2. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  3. First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders.
    Olivieri G; Bordugo A; Burnyte B; Costetti A; Couce ML; Diogo L; Feillet F; Froese DS; Greco B; Gueant JL; Hannibal L; Hörster F; Kožich V; La Marca G; Manoli I; Mochel F; Orazi L; Pérez B; Schiff M; Schwahn BC; Schwartz I; Stepien KM; Sykut-Cegielska J; Tangeraas T; Zetterström RH; Dionisi-Vici C; Huemer M · Journal of inherited metabolic disease · 2026
    Guideline / consensusMetabolism Boost forVitamin B12
  4. Vitamin B12 and Folate Concentrations in Recent-onset Type 2 Diabetes and the Effect of Metformin Treatment.
    Kanti G; Anadol-Schmitz E; Bobrov P; Strassburger K; Kahl S; Zaharia OP; Sarabhai T; Karusheva Y; Burkart V; Markgraf DF; Trenkamp S; Ziegler D; Szendroedi J; Roden M; GDS Group · The Journal of clinical endocrinology and metabolism · 2021
    Cross-sectional study249 participantsMetabolism Boost forVitamin B12
  5. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  6. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  7. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  8. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  9. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  10. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  11. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  12. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  13. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  14. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  15. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  16. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin
  17. Vitamin B12 Status and Cardiovascular Risk: Novel Insights from NMR-Based Lipoprotein Profiling in 20,665 Adults.
    Eken Y; Tekin N; Şahin F; Tay İ; Yıldırım Saral N; Serteser M; Baykal AT · Journal of clinical medicine · 2026
    Cross-sectional study20,665 participantsCardiovascular Support Heart Health forVitamin B12
  18. Pregnancy Metal Mixtures and Blood Pressure and Hypertension in Mid-Life: A Prospective U.S. Cohort Study.
    Zhang M; Aris IM; Cardenas A; Rifas-Shiman SL; Lin PD; Ngo LH; Oken E; Hivert MF; Juraschek SP · Hypertension (Dallas, Tex. : 1979) · 2025
    Cohort study493 participantsCardiovascular Support forVitamin B12
  19. Vitamin B12 Deficiency, Hyperhomocysteinemia, and Diabetes as Metabolic Determinants of Cardiovascular Risk in Mexican Women.
    Ramirez-Villalobos MD; Monterrubio-Flores E; Marquez-Murillo M; Alcalde-Rabanal J; Shamah-Levy T; Perichart-Perera O; Macias-Morales N; Campos-Nonato I · Nutrients · 2025
    Cross-sectional study1,197 participantsCardiovascular Support forVitamin B12
  20. Impact of serum vitamin (Vitamin D, Vitamin B12) and trace element (Fe, Zn, Cu) levels on major adverse cardiovascular events and poor prognosis in STEMI patients undergoing primary PCI.
    Wang C; Liu D; Tang M; Liu J; Ma Y · Journal of clinical biochemistry and nutrition · 2026
    Cohort study202 participantsCardiovascular Support forVitamin B12
  21. Vasoplegic syndrome after cardiovascular surgery: A review of pathophysiology and outcome-oriented therapeutic management.
    Datt V; Wadhhwa R; Sharma V; Virmani S; Minhas HS; Malik S · Journal of cardiac surgery · 2021
    Systematic reviewCardiovascular Support forVitamin B12
  22. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  23. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  24. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  25. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  26. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  27. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  28. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  29. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  30. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  31. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  32. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  33. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  34. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  35. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  36. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  37. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  38. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  39. A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia.
    Draelos ZD; Jacobson EL; Kim H; Kim M; Jacobson MK · Journal of cosmetic dermatology · 2009
    Randomized trial60 participantsHair Health forNiacin
  40. Topical adenosine increases thick hair ratio in Japanese men with androgenetic alopecia.
    Watanabe Y; Nagashima T; Hanzawa N; Ishino A; Nakazawa Y; Ogo M; Iwabuchi T; Tajima M · International journal of cosmetic science · 2016
    Randomized trial102 participantsHair Health forNiacin
  41. Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
    Qin X; Li J; Spence JD; Zhang Y; Li Y; Wang X; Wang B; Sun N; Chen F; Guo J; Yin D; Sun L; Tang G; He M; Fu J; Cai Y; Shi X; Ye P; Chen H; Zhao S; Chen M; Gao C; Kong X; Hou FF; Huang Y; Huo Y · Stroke · 2017
    Randomized trial20,702 participantsHeart Health forFolate
  42. Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease : Nested Case-Control and Mendelian Randomization Studies.
    Chen H; Zhang Y; Wang D; Chen X; Li M; Huang X; Jiang Y; Dou Y; Wang Y; Ma X; Sheng W; Jia B; Yan W; Huang G; SPCC (Shanghai Preconception Cohort) Group · Annals of internal medicine · 2022
    Case-control study985 participantsHeart Health forFolate
  43. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forFolate
  44. Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
    Fallah M; Karim Dehnavi M; Lotfi K; Aminianfar A; Azadbakht L; Esmaillzadeh A · Nutrition reviews · 2025
    Meta-analysis423,304 participants25 studies pooledHeart Health forFolate
  45. The association between folic acid supplementation and congenital heart defects: Systematic review and meta-analysis.
    Wondemagegn AT; Afework M · SAGE open medicine · 2022
    Meta-analysis37 studies pooledHeart Health forFolate
  46. Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes.
    Hansen CS; Jensen JS; Ridderstråle M; Vistisen D; Jørgensen ME; Fleischer J · Journal of diabetes and its complications · 2018
    Cross-sectional study469 participantsHeart Health forVitamin B12
  47. Vitamin B12 and folate status in early pregnancy and cardiometabolic risk factors in the offspring at age 5-6 years: findings from the ABCD multi-ethnic birth cohort.
    Krikke GG; Grooten IJ; Vrijkotte TG; van Eijsden M; Roseboom TJ; Painter RC · BJOG : an international journal of obstetrics and gynaecology · 2016
    Cohort study1,950 participantsHeart Health forVitamin B12
  48. Orthostatic tolerance in older patients with vitamin B12 deficiency before and after vitamin B12 replacement.
    Moore A; Ryan J; Watts M; Pillay I; Clinch D; Lyons D · Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2004
    Non-randomized trial16 participantsHeart Health forVitamin B12
  49. The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
    Liang X; Huang D; Bi Y; He Y; Mao T; Liu Q; Hu G; Tong J; Chen L; Wang Y; An X; Jiang X; Tahir MF · Journal of human hypertension · 2024
    Observational study596 participantsHeart Health forVitamin B12
  50. Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes: a prospective UK cohort study (PRiDE study).
    Saravanan P; Sukumar N; Adaikalakoteswari A; Goljan I; Venkataraman H; Gopinath A; Bagias C; Yajnik CS; Stallard N; Ghebremichael-Weldeselassie Y; Fall CHD · Diabetologia · 2022
    Cohort study4,746 participantsMetabolism Boost forVitamin B12
  51. Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism.
    Carmel R; Melnyk S; James SJ · Blood · 2003
    Observational study39 participantsMetabolism Boost forVitamin B12
  52. Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis.
    Mazur M; Ndokaj A; Salerno C; Vallone J; Ardan R; Bietolini S; Carrouel F; Wilk A; Sarig R; Ottolenghi L; Bourgeois D · Frontiers in pharmacology · 2026
    Meta-analysis6,098 participants16 studies pooledMetabolism Boost forVitamin B12
  53. Diagnosis and treatment of vitamin B12 deficiency in children.
    Kanvinde P; Khurana R; Mudaliar S · Frontiers in nutrition · 2026
    Narrative reviewMetabolism Boost forVitamin B12