Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Lipid profile and glucose changes after supplementation with astaxanthin: a systematic review and meta-analysis of randomized controlled trials.
Ursoniu S; Sahebkar A; Serban MC; Banach M · Archives of medical science : AMS · 2015
Meta-analysis280 participants7 studies pooledflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- Astaxanthin (AstaReal®) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial.
Hecht KA; Marwah M; Wood V; Nishida Y; Bach AE; Gerson J; Hom MM; Schnackenberg J; Raote S; Srivastava S; Negi P; Caston E · Advances in therapy · 2025
Randomized trial64 participantsflagVision Support forscienceAstaxanthin
- Assessing the Effects of Moderate to High Dosage of Astaxanthin Supplementation on Lipid Profile Parameters-A Systematic Review and Meta-Analysis of Randomized Controlled Studies.
Fornari Laurindo L; Dogani Rodrigues V; Penna Carneiro D; Sérgio Marangão Filho L; Pereira ESBM; José Tofano R; Chagas EFB; Dos Santos Haber JF; Cristina Castilho Caracio F; Moreira LZ; Valenti VE; Maria Barbalho S · Pharmaceuticals (Basel, Switzerland) · 2025
Meta-analysis8 studies pooledflagHeart Health forscienceAstaxanthin
- Effectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials.
Yang Q; Li H; Zhang H; Ma L; Zhang X; Wu J · Frontiers in medicine · 2025
Meta-analysis40 studies pooledflagSkin Health forscienceAstaxanthin
- Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing.
Zhou X; Cao Q; Orfila C; Zhao J; Zhang L · Nutrients · 2021
Meta-analysis11 studies pooledflagSkin Health flagAnti-Aging forscienceAstaxanthin
- Sports and Kinetic Visual Acuity.
Sawaki K; Kohmura Y; Aoki K; Nakamura M; Murakami S; Suzuki Y · Juntendo Iji zasshi = Juntendo medical journal · 2024
Narrative reviewflagVision Support forscienceAstaxanthin
- Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia.
Ciaraldi TP; Boeder SC; Mudaliar SR; Giovannetti ER; Henry RR; Pettus JH · Diabetes, obesity & metabolism · 2023
Randomized trial34 participantsflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial.
Ito N; Seki S; Ueda F · Nutrients · 2018
Randomized trial23 participantsflagSkin Health forscienceAstaxanthin
- Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Leung LY; Chan SM; Tam HL; Wong ES · Nutrients · 2022
Meta-analysis321 participants7 studies pooledflagHeart Health forscienceAstaxanthin
- Effects of diet containing astaxanthin on visual function in healthy individuals: a randomized, double-blind, placebo-controlled, parallel study.
Sekikawa T; Kizawa Y; Li Y; Miura N · Journal of clinical biochemistry and nutrition · 2023
Randomized trial60 participantsflagVision Support forscienceAstaxanthin
- Effects of Astaxanthin supplementation on selected metabolic parameters, anthropometric indices, Sirtuin1 and TNF-α levels in patients with coronary artery disease: A randomized, double-blind, placebo-controlled clinical trial.
Heidari M; Chaboksafar M; Alizadeh M; Sohrabi B; Kheirouri S · Frontiers in nutrition · 2023
Randomized trial50 participantsflagCardiovascular Support forscienceAstaxanthin
- Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Wan S; Wu W; Zhang Y; He J; Wang X; An P; Luo J; Zhu Y; Luo Y · Nutrients · 2024
Meta-analysisflagHeart Health flagCardiovascular Support forscienceAstaxanthin
- Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo.
Yoon HS; Cho HH; Cho S; Lee SR; Shin MH; Chung JH · Journal of medicinal food · 2015
Randomized trial44 participantsflagSkin Health forscienceAstaxanthin
- Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease.
Tian L; Wen Y; Li S; Zhang P; Wang Y; Wang J; Cao K; Du L; Wang N; Jie Y · Frontiers in nutrition · 2022
Single-arm trial60 participantsflagVision Support forscienceAstaxanthin
- Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia.
Yoshida H; Yanai H; Ito K; Tomono Y; Koikeda T; Tsukahara H; Tada N · Atherosclerosis · 2010
Randomized trial61 participantsflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- The effect of astaxanthin supplementation on inflammatory markers, lipid profile, and anthropometric indices in patients with heart failure: a randomized controlled trial.
Ghotboddin Mohammadi S; Shafie D; Feizi A; Ahmadi AR; Bagherniya M; Kafeshani M · Scientific reports · 2026
Randomized trial80 participantsflagHeart Health flagCardiovascular Support forscienceAstaxanthin
- Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers.
Chalyk NE; Klochkov VA; Bandaletova TY; Kyle NH; Petyaev IM · Nutrition research (New York, N.Y.) · 2018
Single-arm trial31 participantsflagSkin Health forscienceAstaxanthin
- Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
Martinez-Perez C; Oliveira AP · Nutrients · 2026
Systematic review9 studies pooledflagVision Support forscienceAstaxanthin
- Effects of Astaxanthin Supplementation on Glycemic Control and Lipid Profile in Patients With Prediabetes and Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.
Molani-Gol R; Bohlouli Sardroudi S; Rafraf M · Nutrition and metabolic insights · 2026
Meta-analysis403 participants9 studies pooledflagCardiovascular Support flagHeart Health forscienceAstaxanthin
- The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.
Phetcharat L; Wongsuphasawat K; Winther K · Clinical interventions in aging · 2016
Randomized trial34 participantsflagSkin Health flagAnti-Aging forscienceAstaxanthin
- Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential.
Kidd P · Alternative medicine review : a journal of clinical therapeutic · 2012
Narrative reviewflagVision Support flagAnti-Aging forscienceAstaxanthin
- Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity.
Saeidi A; Nouri-Habashi A; Razi O; Ataeinosrat A; Rahmani H; Mollabashi SS; Bagherzadeh-Rahmani B; Aghdam SM; Khalajzadeh L; Al Kiyumi MH; Hackney AC; Laher I; Heinrich KM; Zouhal H · Nutrients · 2023
Randomized trial68 participantsflagCardiovascular Support forscienceAstaxanthin
- Cosmetic benefits of astaxanthin on humans subjects.
Tominaga K; Hongo N; Karato M; Yamashita E · Acta biochimica Polonica · 2012
Other66 participantsflagSkin Health forscienceAstaxanthin
- Astaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial).
Coombes JS; Sharman JE; Fassett RG · The American journal of clinical nutrition · 2016
Randomized trial61 participantsflagHeart Health forscienceAstaxanthin
- The Xanthophyll Carotenoid Astaxanthin has Distinct Biological Effects to Prevent the Photoaging of the Skin Even by its Postirradiation Treatment.
Imokawa G · Photochemistry and photobiology · 2019
Narrative reviewflagSkin Health forscienceAstaxanthin
- Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indications.
Singh KN; Patil S; Barkate H · Journal of cosmetic dermatology · 2020
Narrative reviewflagSkin Health forscienceAstaxanthin
- Astaxanthin, oxidative stress, inflammation and cardiovascular disease.
Fassett RG; Coombes JS · Future cardiology · 2009
Narrative reviewflagCardiovascular Support forscienceAstaxanthin
- Impact of astaxanthin on oxidative markers, uric acid, and clinical symptoms in heart failure: a randomized clinical trial.
Mohammadi SG; Shafie D; Feizi A; Bagherniya M; Ahmadi AR; Kafeshani M · BMC cardiovascular disorders · 2025
Randomized trial80 participantsflagHeart Health forscienceAstaxanthin
- Preparation and in vitro characterization studies of astaxanthin-loaded nanostructured lipid carriers with antioxidant properties.
Gu L; Wang W; Wu B; Ji S; Xia Q · Journal of biomaterials applications · 2023
In vitro / ex vivo studyflagSkin Health forscienceAstaxanthin
- The effect of astaxanthin supplementation on inflammatory markers, oxidative stress indices, lipid profile, uric acid level, blood pressure, endothelial function, quality of life, and disease symptoms in heart failure subjects.
Mohammadi SG; Feizi A; Bagherniya M; Shafie D; Ahmadi AR; Kafeshani M · Trials · 2024
Protocol80 participantsflagCardiovascular Support forscienceAstaxanthin
- Markers of Hypoxia and Oxidative Stress in Aging Volunteers Ingesting Lycosomal Formulation of Dark Chocolate Containing Astaxanthin.
Petyaev IM; Klochkov VA; Chalyk NE; Pristensky DV; Chernyshova MP; Kyle NH; Bashmakov YK · The journal of nutrition, health & aging · 2019
Randomized trial32 participantsflagAnti-Aging forscienceAstaxanthin
- The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial.
Youssef FM; Ateyya H; Hanna Samy AE; Elmokadem EM · Frontiers in pharmacology · 2025
Randomized trial80 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- The Role of Astaxanthin as an Antioxidant and Anti-Inflammatory Agent in Human Health: A Systematic Review.
Malcangi G; Inchingolo AM; Casamassima L; Trilli I; Ferrante L; Longo M; Inchingolo F; Marinelli G; Palermo A; Dipalma G; Inchingolo AD · International journal of molecular sciences · 2026
Systematic review15 studies pooledflagAnti-Inflammatory Support forscienceAstaxanthin
- Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial.
Rostami S; Alyasin A; Saedi M; Nekoonam S; Khodarahmian M; Moeini A; Amidi F · Frontiers in endocrinology · 2023
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Astaxanthin Modulates Inflammation in Type 2 Diabetes via Regulation of microRNAs, Lysophosphatidylcholine, and α-Hydroxybutyrate.
Sharifi-Rigi A; Zal F; Aarabi MH; Dehghani M; Roustaei Rad N; Taghiyar S · International journal of endocrinology · 2025
Randomized trial50 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes.
Basereh A; Khoramipour K; Hosseini N; HajHosseini M; Khodabakhshi A; Amirkhosravi L; Khoramipour K · Scientific reports · 2025
Randomized trial90 participantsflagAnti-Inflammatory Support forscienceAstaxanthin
- Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study.
Katagiri M; Satoh A; Tsuji S; Shirasawa T · Journal of clinical biochemistry and nutrition · 2012
Randomized trial96 participantsflagCognitive Support forscienceAstaxanthin
- Effect of astaxanthin-rich extract derived from Paracoccus carotinifaciens on cognitive function in middle-aged and older individuals.
Hayashi M; Ishibashi T; Maoka T · Journal of clinical biochemistry and nutrition · 2020
Clinical trial54 participantsflagCognitive Support forscienceAstaxanthin
- The Effects of Astaxanthin on Cognitive Function and Neurodegeneration in Humans: A Critical Review.
Queen CJJ; Sparks SA; Marchant DC; McNaughton LR · Nutrients · 2024
Narrative reviewflagCognitive Support forscienceAstaxanthin
- Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials.
Liu C; Dong X; Jia J; Ha M · Biological research for nursing · 2024
Meta-analysis346 participants11 studies pooledflagCognitive Support forscienceAstaxanthin
- Astaxanthin and improvement of dementia: A systematic review of current clinical trials.
Utomo NP; Pinzon RT; Latumahina PK; Damayanti KRS · Cerebral circulation - cognition and behavior · 2024
Systematic reviewflagCognitive Support forscienceAstaxanthin
- Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial.
Grigorian A; Tabatabaeyan A; Salesi M; Feizi A; Ahmadi AR; Kafeshani M · Food & function · 2025
Randomized trial60 participantsflagJoint Health forscienceAstaxanthin
- A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of a Krill Oil, Astaxanthin, and Oral Hyaluronic Acid Complex on Joint Health in People with Mild Osteoarthritis.
Hill WS; Dohnalek MH; Ha Y; Kim SJ; Jung JC; Kang SB · Nutrients · 2023
Randomized trial100 participantsflagJoint Health forscienceAstaxanthin