Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study.
Chung BY; Park SY; Jung MJ; Kim HO; Park CW · Annals of dermatology · 2022
Randomized trial50 participantsflagSkin Health forscienceGamma Linolenic Acid
- Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response.
Morse PF; Horrobin DF; Manku MS; Stewart JC; Allen R; Littlewood S; Wright S; Burton J; Gould DJ; Holt PJ · The British journal of dermatology · 1989
Meta-analysis9 studies pooledflagSkin Health forscienceGamma Linolenic Acid
- Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people.
Brosche T; Platt D · Archives of gerontology and geriatrics · 2005
Non-randomized trial29 participantsflagSkin Health forscienceGamma Linolenic Acid
- Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy.
Manku MS; Horrobin DF; Morse N; Kyte V; Jenkins K; Wright S; Burton JL · Prostaglandins, leukotrienes, and medicine · 1983
Non-randomized trial50 participantsflagSkin Health forscienceGamma Linolenic Acid
- Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients.
Yoshimoto-Furuie K; Yoshimoto K; Tanaka T; Saima S; Kikuchi Y; Shay J; Horrobin DF; Echizen H · Nephron · 1999
Randomized trial16 participantsflagSkin Health forscienceGamma Linolenic Acid
- Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis.
Tollesson A; Frithz A · Acta dermato-venereologica · 1993
Single-arm trial37 participantsflagSkin Health forscienceGamma Linolenic Acid
- Essential fatty acid metabolism and its modification in atopic eczema.
Horrobin DF · The American journal of clinical nutrition · 2000
Narrative reviewflagSkin Health forscienceGamma Linolenic Acid
- Evening primrose oil (Epogam) in the treatment of chronic hand dermatitis: disappointing therapeutic results.
Whitaker DK; Cilliers J; de Beer C · Dermatology (Basel, Switzerland) · 1997
Randomized trial39 participantsflagSkin Health forscienceGamma Linolenic Acid
- Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
Belch JJ; Ansell D; Madhok R; O'Dowd A; Sturrock RD · Annals of the rheumatic diseases · 1988
Randomized trial49 participantsflagAnti-Inflammatory Support forscienceGamma Linolenic Acid
- Systemic immune inflammation mediates the association of serum omega-3 and omega-6 polyunsaturated fatty acids with biological aging: a national population-based study.
Shan F; Xiong Y; Pai P; Liu M · Aging clinical and experimental research · 2025
Cross-sectional study3,376 participantsflagAnti-Inflammatory Support forscienceGamma Linolenic Acid
- Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis.
Cameron M; Gagnier JJ; Little CV; Parsons TJ; Blümle A; Chrubasik S · Phytotherapy research : PTR · 2010
Meta-analysis20 studies pooledflagAnti-Inflammatory Support forscienceGamma Linolenic Acid
- Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.
Brzeski M; Madhok R; Capell HA · British journal of rheumatology · 1991
Randomized trial40 participantsflagAnti-Inflammatory Support forscienceGamma Linolenic Acid
- Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ɣ-linolenic acid-containing botanical oils.
Sergeant S; Hallmark B; Mathias RA; Mustin TL; Ivester P; Bohannon ML; Ruczinski I; Johnstone L; Seeds MC; Chilton FH · The American journal of clinical nutrition · 2020
Randomized trial64 participantsflagAnti-Inflammatory Support forscienceGamma Linolenic Acid
- Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews.
Christie A; Jamtvedt G; Dahm KT; Moe RH; Haavardsholm EA; Hagen KB · Physical therapy · 2008
Systematic review28 studies pooledflagJoint Health forscienceGamma Linolenic Acid
- Herbal therapy for treating rheumatoid arthritis.
Little C; Parsons T · The Cochrane database of systematic reviews · 2001
Systematic review11 studies pooledflagJoint Health forscienceGamma Linolenic Acid
- Herbal medicines for the treatment of rheumatoid arthritis: a systematic review.
Soeken KL; Miller SA; Ernst E · Rheumatology (Oxford, England) · 2003
Systematic review14 studies pooledflagJoint Health forscienceGamma Linolenic Acid
- gamma-Linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial.
Zurier RB; Rossetti RG; Jacobson EW; DeMarco DM; Liu NY; Temming JE; White BM; Laposata M · Arthritis and rheumatism · 1996
Randomized trial56 participantsflagJoint Health forscienceGamma Linolenic Acid
- Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis.
Rothman D; DeLuca P; Zurier RB · Seminars in arthritis and rheumatism · 1996
Narrative reviewflagJoint Health forscienceGamma Linolenic Acid
- Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
Randomized trial43 participantsflagJoint Health forscienceOmega-3
- Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
Randomized trial235 participantsflagJoint Health forscienceOmega-3
- Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
Meta-analysis1,018 participants18 studies pooledflagJoint Health forscienceOmega-3
- Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
Meta-analysis1,420 participants30 studies pooledflagJoint Health forscienceOmega-3
- A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
Goldberg RJ; Katz J · Pain · 2007
Meta-analysis17 studies pooledflagJoint Health forscienceOmega-3
- Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
Meta-analysis331 participants6 studies pooledflagMetabolism Boost forscienceOmega-3
- Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
Randomized trial38 participantsflagMetabolism Boost forscienceOmega-3
- Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
Randomized trial60 participantsflagMetabolism Boost flagSkin Health forscienceOmega-3
- The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
Randomized trial60 participantsflagMetabolism Boost forscienceOmega-3
- A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
Randomized trial200 participantsflagMetabolism Boost forscienceOmega-3
- Dietetic intervention in psoriatic arthritis: the DIETA trial.
Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
Randomized trial97 participantsflagSkin Health forscienceOmega-3
- Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
Randomized trial49 participantsflagSkin Health forscienceOmega-3
- Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
Randomized trial50 participantsflagSkin Health forscienceOmega-3
- Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
Randomized trial42 participantsflagSkin Health forscienceOmega-3
- Psychosocial Burden in People with Atopic Dermatitis: Effects of a Substance-Free Basic Skincare in a Randomized Health Care Study.
Braren-von Stülpnagel C; Augustin M; Sommer R; Westphal L · Skin pharmacology and physiology · 2024
Randomized trial79 participantsflagSkin Health forscienceOmega-6
- Abnormalities in epidermal lipid metabolism in patients with atopic dermatitis.
Schäfer L; Kragballe K · The Journal of investigative dermatology · 1991
Cross-sectional study15 participantsflagSkin Health forscienceOmega-6
- Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years.
Pike KC; Calder PC; Inskip HM; Robinson SM; Roberts GC; Cooper C; Godfrey KM; Lucas JS · Clinical & developmental immunology · 2013
Cohort study865 participantsflagSkin Health forscienceOmega-6
- Plasma omega-3 and omega-6 concentrations and risk of cutaneous basal and squamous cell carcinomas in Australian adults.
Wallingford SC; Hughes MC; Green AC; van der Pols JC · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
Cohort study1,191 participantsflagSkin Health forscienceOmega-6
- Maternal PUFA status and offspring allergic diseases up to the age of 18 months.
Yu YM; Chan YH; Calder PC; Hardjojo A; Soh SE; Lim AL; Fisk HL; Teoh OH; Goh A; Saw SM; Kwek K; Gluckman PD; Godfrey KM; Chong YS; Shek LP; Pan A; Chong MF; van Bever HP; GUSTO study group · The British journal of nutrition · 2015
Cohort study960 participantsflagSkin Health forscienceOmega-6