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Ultra-Mag

Source Naturals
4.9
★ ★ ★ ★ ★
(54473 ratings)
Magnesium 400 mg
Vitamin B6 30 mg
Product Image
Score81
A convenient multi-form magnesium tablet with strong label potency. Hidden form proportions and a high pyridoxine amount complicate long-term use.
How scoring works
Quantity:120 Tablet(s) • (60 servings)
Goals:
Energy
Sleep Support
Stress Relief
General Health
Testosterone Support
Cardiovascular Support
Heart Health
Bone Health
Productivity Boost
Digestive Health

Score 81

A convenient multi-form magnesium tablet with strong label potency. Hidden form proportions and a high pyridoxine amount complicate long-term use.
How scoring works
$15.39($0.25 per serving)
Vitacost
$ 15.39
Pure Formulas
$ 15.39
iHerb
$ 15.39
Report prices

Analysis

Citrate, glycinate, malate, succinate, and taurinate provide a broad set of magnesium forms for normal muscle, nerve, cardiovascular, and energy functions. Vitamin B6 adds a related metabolic cofactor.

The label does not show how much magnesium comes from each form or whether the chelates are fully reacted. Pyridoxine hydrochloride is less direct than P-5-P and is supplied at a substantial long-term amount.

The one-tablet serving is convenient and offers good mineral depth. Sleep, stress, productivity, and testosterone effects remain foundational rather than direct, and digestive tolerance may determine practical use.

Who is it for
  • Adults wanting several magnesium forms
  • Users seeking a one-tablet serving
  • People monitoring vitamin B6 intake
Best for
  • General magnesium support
  • Nutrient-related sleep and stress routines
  • Muscle and cardiovascular nutrition

Pros

  • Several organic magnesium forms
  • Substantial elemental amount
  • One-tablet serving
  • Practical recurring value

Cons

  • Form proportions are not disclosed
  • Pyridoxine rather than P-5-P
  • High total magnesium
  • Multiple forms add complexity without distinct pathways

Warnings

  • The 400 mg magnesium amount may cause diarrhea or abdominal discomfort.
  • Long-term daily use of 30 mg vitamin B6 may raise the risk of tingling or numbness.
  • People with impaired kidney function should avoid high-dose magnesium without professional guidance.

Nutrient quality

85 Highest impact

Citrate, glycinate, malate, succinate, and taurinate provide a strong organic magnesium mix. The magnesium total and vitamin B6 amount are both substantial.

.

Ingredient transparency

75 High impact

Most main amounts are shown, but some form shares or blend details remain unclear. The supplied data does not include a complete inactive ingredient list.

.

Customer satisfaction

74 High impact

The aggregate satisfaction measure is supported by adequate volume. Missing feedback themes leave recurring complaints and purpose fit uncertain.

.

Value for money

92 Highest impact

The price is very well matched to the formula quality and dose. Each serving provides excellent cost efficiency.

.
Report analysis

Goals

Energy
Energy
Impact
Highest effect
A Goal FitA Strength of SupportB- CoverageA- Formula Quality
Magnesium · 400 mg

A substantial magnesium amount plus vitamin B6 supports ATP production, nutrient metabolism, nerves, and muscles. Glycinate, malate, taurinate, citrate, and succinate create a generally well-absorbed mineral profile.

Vitamin B6 adds a useful metabolic cofactor, giving the blend more depth than plain magnesium. Multiple magnesium forms add some redundancy, but the formula remains centered on foundational energy rather than stimulation.

Study evidence
Magnesium Supportive 4 studies
Sleep Support
Sleep Support
Impact
Highest effect
A+ Goal FitA- Strength of SupportC+ CoverageB Formula Quality
Magnesium · 400 mg

The multi-form magnesium blend provides 400 mg of a foundational mineral used in energy metabolism, muscle function, and nervous-system regulation. Citrate, glycinate, malate, succinate, and taurinate offer generally favorable absorption potential.

The 30 mg B6 amount is high for long-term daily use, especially alongside other B6 supplements, because excessive cumulative intake can cause nerve symptoms. The label also does not state how much magnesium comes from each form or whether the chelates are fully reacted.

Study evidence
Magnesium Supportive 23 studies
Stress Relief
Stress Relief
Impact
Highest effect
B Goal FitA Strength of SupportB CoverageA- Formula Quality
Magnesium · 400 mgVitamin B6 · 30 mg

A 400 mg magnesium blend with vitamin B6 provides substantial nervous-system and metabolic support relevant to stress resilience. Multiple organic forms improve the absorption profile compared with oxide-heavy products, although they do not create several distinct stress pathways.

The label identifies citrate, glycinate, malate, succinate, and taurinate but does not state how much each contributes. The 30 mg pyridoxine amount is substantial, and long-term stacking with other vitamin B6 products could raise the risk of nerve symptoms.

Study evidence
Magnesium Supportive 13 studies
Vitamin B6 Supportive 10 studies
General Health
General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 400 mg

A blend of organic magnesium forms provides broad support for normal muscle, nerve, and energy-related functions. The elemental amount is meaningful and the forms are clearly named.

Individual magnesium-form proportions are not disclosed, so the contribution of each cannot be judged. Long-term daily use of 30 mg vitamin B6 may increase nerve-symptom risk in susceptible users.

Study evidence
Magnesium Supportive 114 studies
Testosterone Support
Testosterone Support
Impact
Highest effect
B Goal FitA Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 400 mg

A 400 mg blend of citrate, glycinate, malate, succinate, and taurate provides strong magnesium support in well-absorbed forms. Vitamin B6 adds a complementary cofactor for hormone regulation.

The one-tablet serving has useful depth and a clear endocrine rationale. Pyridoxine hydrochloride is less metabolically direct than P-5-P, and the magnesium dose may cause digestive upset or accumulate when kidney function is impaired.

Study evidence
Magnesium Disputed 5 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B+ Goal FitA Strength of SupportC CoverageB Formula Quality
Magnesium · 400 mgVitamin B6 · 30 mg

A blend of citrate, glycinate, malate, succinate, and taurate provides strong magnesium support for vascular tone and cardiac rhythm. The substantial elemental amount and several absorbable forms give the single pathway useful depth.

Vitamin B6 adds metabolic support but is not essential to the cardiovascular strategy. Continued daily intake of 30 mg vitamin B6 may raise neuropathy risk, especially when combined with other B6 products.

Study evidence
Magnesium Supportive 123 studies
Vitamin B6 Supportive 35 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s)
Vitamin B6 (Pyridoxine Hydrochloride)
 30 mg
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Malate, Magnesium Succinate, Magnesium Taurinate)
 400 mg
Sodium
5 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Magnesium (Magnesium Citrate, Magnesium Glycinate, Magnesium Malate, Magnesium Succinate, Magnesium Taurinate) · 400 mg OverallScore88
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
+2

A blend of citrate and several premium organic forms supports good absorption potential. The label provides 400 mg of magnesium and adds vitamin B6 for formulation synergy. Low serving cost supports strong value, though no patented or fully reacted chelation standard is disclosed.

View ingredientView products
Vitamin B6 (Pyridoxine Hydrochloride) · 30 mg OverallScore74
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The 30 mg dose falls within the preferred range, but it uses pyridoxine hydrochloride rather than active P-5-P. One tablet provides a practical serving, and no concerning additives are disclosed in the supplied data. Value is fair for an inactive B6 form rather than exceptional.

View ingredientView products
Loading alternative details
79 Performance

Magnesium Taurate +

KAL
<p>Magnesium taurate and active P-5-P provide a well-dosed combination that covers both original nutrient groups. Compared with the original, taurate and active P-5-P improve magnesium and B6 form quality. The high supplemental magnesium and B6 amounts may affect tolerability with prolonged use.</p>
91 Performance

Krebs Magnesium Potassium Complex

Nature's Way
<p>Magnesium lysinate and malate provide favorable forms at a useful amount, with modest potassium. The chelated magnesium forms provide a well-absorbed alternative to the original high-dose blend or single taurate form. It omits vitamin B6, so it is not a complete one-product replacement for the original combination.</p>
89 Performance

P-5-P 50 mg

Country Life
<p>Active pyridoxal phosphate provides a meaningful and metabolically ready vitamin B6 serving. The active B6 form improves on the original pyridoxine and can complement a separately chosen magnesium product. It omits magnesium, and the substantial B6 amount warrants care with long-term daily use.</p>
83 Budget

Magnesium Citrate Pure Powder

Best Naturals
<p>Magnesium citrate supplies a useful amount in an adjustable and clearly labeled powder. Its lower serving cost makes it a more economical way to cover one part of the original combination. It omits vitamin B6, and citrate may loosen stools in sensitive users.</p>
85 Budget

Vitamin B6 25 mg

Solgar
<p>A focused vitamin B6 serving matches the original B6 amount without adding other active ingredients. Its lower serving cost makes it a more economical way to cover one part of the original combination. Pyridoxine is less direct than active P-5-P, and the product omits magnesium.</p>
84 Budget

P-5-P 50 mg

Nutricost
<p>Active P-5-P provides ready-to-use vitamin B6 in a simple capsule. Its lower serving cost makes it a more economical way to cover one part of the original combination. The high B6 amount may add nerve-related risk with prolonged daily use, and magnesium is absent.</p>
88 Value

Magnesium Bisglycinate Powder

NOW
<p>Magnesium bisglycinate provides a well-absorbed form at a practical amount in an adjustable powder. The lower serving cost and stronger single-nutrient form improve value, provided the missing nutrient is supplied elsewhere. It omits vitamin B6, so users seeking both nutrients would need a separate B6 source.</p>
89 Value

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
<p>Active pyridoxal phosphate provides a meaningful vitamin B6 serving at a low serving cost. The lower serving cost and stronger single-nutrient form improve value, provided the missing nutrient is supplied elsewhere. It omits magnesium, and prolonged daily use of the substantial B6 amount may add nerve-related risk.</p>
85 Value

Magnesium Bisglycinate Chelate

Healthy Origins
<p>TRAACS magnesium bisglycinate provides a premium chelated form and a useful elemental amount. The lower serving cost and stronger single-nutrient form improve value, provided the missing nutrient is supplied elsewhere. It is a magnesium-only powder, so it does not replace the original vitamin B6 component.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  2. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  3. Effect of magnesium supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials.
    Darooghegi Mofrad M; Djafarian K; Mozaffari H; Shab-Bidar S · Atherosclerosis · 2019
    Meta-analysis306 participants7 studies pooledCardiovascular Support forMagnesium
  4. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsCardiovascular Support forMagnesium
  5. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  6. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  7. Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
    Yoneda H; Tomita T; Kitano T; Morishita D; Kodani M; Nishii N; Sei H; Eda H; Sato T; Kawai M; Yokoyama Y; Igeta M; Okugawa T; Fukui H; Shinzaki S · Neurogastroenterology and motility · 2026
    Randomized trial40 participantsDigestive Health forMagnesium
  8. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  9. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  10. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  11. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  12. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  13. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  14. The Effects of the AGE Inhibitor Pyridoxamine on Bone in Older Women With Type 2 Diabetes: A Randomized Clinical Trial.
    Brossfield AV; McMahon DJ; Fernando J; Omeragic B; Majeed R; Agarwal S; Sroga GE; Wang B; Vashishth D; Rubin MR · The Journal of clinical endocrinology and metabolism · 2025
    Randomized trial55 participantsBone Health forVitamin B6
  15. Dietary B vitamin intake and risk of hip fracture: the Singapore Chinese Health Study.
    Dai Z; Wang R; Ang LW; Yuan JM; Koh WP · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Cohort study63,257 participantsBone Health forVitamin B6
  16. Hip fracture patients may be vitamin B6 deficient. Controlled study of serum pyridoxal-5'-phosphate.
    Reynolds TM; Marshall PD; Brain AM · Acta orthopaedica Scandinavica · 1993
    Case-control study103 participantsBone Health forVitamin B6
  17. Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls.
    Saito M; Fujii K; Marumo K · Calcified tissue international · 2006
    Case-control study50 participantsBone Health forVitamin B6
  18. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forVitamin B6
  19. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  20. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  21. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  22. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  23. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  24. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
    Cohort studyCardiovascular Support forVitamin B6
  25. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  26. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  27. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsCardiovascular Support Heart Health forVitamin B6
  28. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6
  29. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  30. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  31. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  32. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  33. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  34. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  35. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  36. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  37. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  38. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  39. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  40. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  41. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  42. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  43. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forVitamin B6
  44. Intake of folate, vitamin B6 and vitamin B12 and the risk of CHD: the Japan Public Health Center-Based Prospective Study Cohort I.
    Ishihara J; Iso H; Inoue M; Iwasaki M; Okada K; Kita Y; Kokubo Y; Okayama A; Tsugane S; JPHC Study Group · Journal of the American College of Nutrition · 2008
    Cohort study40,803 participantsHeart Health forVitamin B6
  45. The effect of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis.
    Miao Y; Guo Y; Chen Y; Lin Y; Lu Y; Guo Q · Nutrition reviews · 2024
    Meta-analysisHeart Health forVitamin B6
  46. Folate and vitamin B(6) intake and risk of acute myocardial infarction in Italy.
    Tavani A; Pelucchi C; Parpinel M; Negri E; La Vecchia C · European journal of clinical nutrition · 2005
    Case-control study985 participantsHeart Health forVitamin B6
  47. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC · European journal of nutrition · 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  48. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J · Neuropsychiatric disease and treatment · 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  49. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsProductivity Boost forMagnesium
  50. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A · Cureus · 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  51. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J · Journal of the American Medical Directors Association · 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  52. Vitamin B6, B9, and B12 Intakes and Cognitive Performance in Elders: National Health and Nutrition Examination Survey, 2011-2014.
    Xu H; Wang S; Gao F; Li C · Neuropsychiatric disease and treatment · 2022
    Cross-sectional study2,421 participantsProductivity Boost forVitamin B6
  53. Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults.
    Coburn SP; Schaltenbrand WE; Mahuren JD; Clausman RJ; Townsend D · The American journal of clinical nutrition · 1983
    Non-randomized trialProductivity Boost forVitamin B6
  54. Identifying Key Predictors of Cognitive Dysfunction in Older People Using Supervised Machine Learning Techniques: Observational Study.
    Rankin D; Black M; Flanagan B; Hughes CF; Moore A; Hoey L; Wallace J; Gill C; Carlin P; Molloy AM; Cunningham C; McNulty H · JMIR medical informatics · 2024
    Cohort studyProductivity Boost forVitamin B6
  55. Inappropriate nutrients intake is associated with lower functional status and inferior quality of life in older adults with depression.
    Guligowska A; Pigłowska M; Fife E; Kostka J; Sołtysik BK; Kroc Ł; Kostka T · Clinical interventions in aging · 2017
    Case-control study49 participantsProductivity Boost forVitamin B6
  56. A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
    Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
    Randomized trial44 participantsProductivity Boost forVitamin B6
  57. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  58. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  59. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  60. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  61. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  62. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  63. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  64. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  65. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  66. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium Stress Relief forVitamin B6
  67. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsStress Relief forVitamin B6
  68. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  69. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  70. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6
  71. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  72. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  73. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  74. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  75. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium