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Bone Builder Forte

Metagenics
4.8
★ ★ ★ ★ ★
(73 ratings)
Phosphorus 168 mg
Calcium 428 mg
Vitamin D 2000 IU
Product Image
Score76
Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. General-health coverage remains limited outside skeletal support, and the dry capsule lacks a stated fat carrier.
How scoring works
Quantity:180 Capsule(s) • (90 servings)
Goals:
General Health
Anti-Aging
Immunity
Testosterone Support
Anti-Inflammatory Support

Score 76

Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. General-health coverage remains limited outside skeletal support, and the dry capsule lacks a stated fat carrier.
How scoring works
$73.95($0.82 per serving)
iHerb
$ 73.95
Report prices

Analysis

Vitamin D3 is paired logically with calcium and phosphorus for focused bone and mineral support. The disclosed vitamin D amount is suitable for routine use and the mineral complex adds relevant depth. General-health coverage remains limited outside skeletal support, and the dry capsule lacks a stated fat carrier.

Vitamin D may help fatigue when low status is a contributor, and the disclosed amount suits routine maintenance. Calcium and phosphorus create a coherent bone-focused formula. The product does not directly support mitochondrial fuel, alertness, or stress resilience.

Microcrystalline hydroxyapatite supplies a bone-like calcium-phosphorus structure at a targeted elemental amount. The compound and elemental yield are both clear, and two capsules provide efficient delivery. A serving cost at the top of the good-value band remains reasonable for the premium source.

Who is it for
  • People seeking general health support
  • People seeking anti-aging support
  • People seeking immunity support
Best for
  • General Health
  • Anti-Aging
  • Immunity

Pros

  • Vitamin D3 is paired logically with calcium and phosphorus for focused bone and mineral support.
  • The disclosed vitamin D amount is suitable for routine use and the mineral complex adds relevant depth.
  • It is a coherent bone-focused product rather than a comprehensive daily wellness formula.
  • Vitamin D3, calcium, and phosphorus provide focused support for maintaining skeletal structure with age.
  • The active amounts are substantial and centered on a mineral matrix similar to bone.

Cons

  • General-health coverage remains limited outside skeletal support, and the dry capsule lacks a stated fat carrier.
  • The dry capsule and missing vitamin D source details limit delivery confidence.
  • The product offers strong depth for bone health but little coverage of mitochondrial, cognitive, or antioxidant pathways.
  • The dry capsule lacks an identified lipid carrier, which may limit absorption compared with an oil-based format.
  • The dose is clear, but the dry capsule lacks a stated lipid carrier for the fat-soluble vitamin.

Nutrient quality

88 Highest impact

Vitamin D uses cholecalciferol, while calcium and phosphorus come from microcrystalline hydroxyapatite. The calcium and vitamin D amounts are meaningful for bone support.

Ingredient transparency

78 High impact

Specific totals are supplied for vitamin D, calcium, phosphorus, and the hydroxyapatite concentrate. Inactive capsule ingredients are not disclosed.

Customer satisfaction

63 Moderate impact

The supplied average and volume indicate strong aggregate satisfaction. No detailed experience reports are available to identify repeated complaints or confirm perceived benefits.

Value for money

73 High impact

The specialized mineral source supports some of the premium cost. Serving value is only moderate for a focused mineral supplement.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Vitamin D · 2000 IU

Vitamin D3 is paired logically with calcium and phosphorus for focused bone and mineral support. The disclosed vitamin D amount is suitable for routine use and the mineral complex adds relevant depth.

General-health coverage remains limited outside skeletal support, and the dry capsule lacks a stated fat carrier. It is a coherent bone-focused product rather than a comprehensive daily wellness formula.

Study evidence
Vitamin D Supportive 115 studies
Anti-Aging
Anti-Aging
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Vitamin D · 2000 IU

Vitamin D3, calcium, and phosphorus provide focused support for maintaining skeletal structure with age. The active amounts are substantial and centered on a mineral matrix similar to bone.

The dry capsule and missing vitamin D source details limit delivery confidence. The product offers strong depth for bone health but little coverage of mitochondrial, cognitive, or antioxidant pathways.

Study evidence
Vitamin D Supportive 50 studies
Immunity
Immunity
Impact
High effect
B+ Goal FitB+ Strength of SupportC CoverageB+ Formula Quality
Vitamin D · 2000 IU

Vitamin D3 is supplied at a meaningful daily amount with direct relevance to immune signaling. The focused dose provides credible maintenance support for users with low vitamin D intake or status.

The dry capsule lacks an identified lipid carrier, which may limit absorption compared with an oil-based format. Most of the formula is devoted to bone minerals, so it offers little coverage of zinc, vitamin C, selenium, or barrier-focused immunity.

Study evidence
Vitamin D Supportive 85 studies
Testosterone Support
Testosterone Support
Impact
High effect
C+ Goal FitA- Strength of SupportD+ CoverageC Formula Quality
Vitamin D · 2000 IU

Vitamin D3 reaches a meaningful targeted amount and provides the formula’s clear testosterone-related rationale. Its value is greatest for people with low vitamin D status.

The remaining calcium and phosphorus ingredients are designed for bone support rather than broader endocrine coverage. The result is a strong single nutrient embedded in a different-purpose formula.

Study evidence
Vitamin D Supportive 56 studies
Anti-Inflammatory Support
Systemic Inflammatory Balance
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB Strength of SupportC- CoverageC Formula Quality
Vitamin D · 2000 IU

Vitamin D3 provides relevant immune-regulating support and reaches a useful maintenance amount. The remaining minerals are aimed primarily at bone health rather than inflammatory pathways.

The dose is clear, but the dry capsule lacks a stated lipid carrier for the fat-soluble vitamin. The product is better suited to bone support than broad anti-inflammatory use.

Study evidence
Vitamin D Supportive 101 studies
Energy
Energy
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportF CoverageC+ Formula Quality
Vitamin D · 2000 IU

Vitamin D may help fatigue when low status is a contributor, and the disclosed amount suits routine maintenance. Calcium and phosphorus create a coherent bone-focused formula.

The product does not directly support mitochondrial fuel, alertness, or stress resilience. It is a poor energy match unless vitamin D inadequacy is specifically involved.

Study evidence
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol)
 2000 IU
Calcium (Microcrystalline Hydroxyapatite Concentrate)
 428 mg
Phosphorus (Microcrystalline Hydroxyapatite Concentrate)
 168 mg
Microcrystalline Hydroxyapatite Concentrate
1.9 Gram(s)
Gluten Free Adults 18–50
Report overview
Phosphorus (Microcrystalline Hydroxyapatite Concentrate) · 168 mg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Microcrystalline hydroxyapatite supplies a bone-like calcium-phosphorus structure at a targeted elemental amount. The compound and elemental yield are both clear, and two capsules provide efficient delivery. A serving cost at the top of the good-value band remains reasonable for the premium source.

View ingredientView products
Calcium (Microcrystalline Hydroxyapatite Concentrate) · 428 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The bone formula uses premium microcrystalline hydroxyapatite at an absorption-efficient amount. The 428 mg serving sits in an absorption-efficient range. The serving cost sits at the upper end of the moderate range. Calcium can reduce absorption of levothyroxine and tetracycline or quinolone antibiotics, so users should separate doses according to their prescription directions.

View ingredientView products
Vitamin D (Cholecalciferol) · 2000 IU OverallScore62
B- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value

Provides vitamin D3 at a well-aligned daily amount alongside bone-focused minerals. The dry capsule lacks a stated lipid carrier, and the D3 raw source is not disclosed. Cost efficiency is weak when evaluated by vitamin D delivery alone.

View ingredientView products
Loading alternative details
88 Performance

Calcium Hydroxyapatite Caps

NOW
<p>The ingredient forms or label detail provide a more purposeful bone-mineral option. Hydroxyapatite supplies clearly dosed calcium with naturally paired phosphorus in a simple capsule. Vitamin D is not included.</p>
80 Performance

Bone Builder Forte

Metagenics
<p>The ingredient forms or label detail provide a more purposeful bone-mineral option. Microcrystalline hydroxyapatite and vitamin D3 provide focused, easy-to-assess bone support. The serving cost remains high compared with simpler mineral formulas.</p>
82 Performance

Calcium Magnesium Citrate Plus Vitamin D-3 Strawberry

LifeTIME
<p>The ingredient forms or label detail provide a more purposeful bone-mineral option. Calcium citrate, magnesium citrate, and vitamin D3 create a focused liquid with clear, useful amounts. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
85 Budget

Calcium Citrate Plus Vitamin D3

Mason Natural
<p>The serving cost is lower than the original. Calcium citrate and vitamin D3 provide a simple formula with good absorption potential. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
80 Budget

Calcium Magnesium Zinc

Nature's Bounty
<p>The serving cost is lower than the original. Calcium, magnesium, zinc, and vitamin D3 provide moderate core amounts in a focused formula. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
82 Budget

Calcium Supplement Petites +D3

Citracal
<p>The serving cost is lower than the original. A moderate calcium amount with vitamin D3 provides simple, conservative bone support. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
80 Value

Target-Mins Calcium Magnesium Complex With Vitamin D3

Country Life
<p>The formula balances useful mineral coverage with practical serving value. Calcium, magnesium, phosphorus, and vitamin D3 use several helpful forms in a coherent bone-mineral blend. Large mineral amounts and magnesium oxide create tolerance and absorption trade-offs.</p>
80 Value

Citracel Maximum Plus

Bayer Citracal
<p>The formula balances useful mineral coverage with practical serving value. Calcium and vitamin D with zinc, copper, and manganese create a broad bone-support formula. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
78 Value

Calcium with Vitamin D3

AN Amazing Nutrition Amazing Formulas
<p>The formula balances useful mineral coverage with practical serving value. Vitamin D3 and substantial calcium create a focused bone-support formula with a simple profile. It does not reproduce the original hydroxyapatite-linked phosphorus coverage.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
    Chowdhury R; Kunutsor S; Vitezova A; Oliver-Williams C; Chowdhury S; Kiefte-de-Jong JC; Khan H; Baena CP; Prabhakaran D; Hoshen MB; Feldman BS; Pan A; Johnson L; Crowe F; Hu FB; Franco OH · BMJ (Clinical research ed.) · 2014
    Meta-analysis95 studies pooledGeneral Health forVitamin D
  2. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  3. The effects of vitamin D on all-cause mortality in different diseases: an evidence-map and umbrella review of 116 randomized controlled trials.
    Cao M; He C; Gong M; Wu S; He J · Frontiers in nutrition · 2023
    Meta-analysis149,865 participants116 studies pooledGeneral Health forVitamin D
  4. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  5. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  6. Vitamin D for the management of multiple sclerosis.
    Jagannath VA; Filippini G; Di Pietrantonj C; Asokan GV; Robak EW; Whamond L; Robinson SA · The Cochrane database of systematic reviews · 2018
    Meta-analysis933 participants12 studies pooledEnergy forVitamin D
  7. Vitamin D levels and menopause-related symptoms.
    LeBlanc ES; Desai M; Perrin N; Wactawski-Wende J; Manson JE; Cauley JA; Michael YL; Tang J; Womack C; Song Y; Johnson KC; O'Sullivan MJ; Woods N; Stefanick ML · Menopause (New York, N.Y.) · 2015
    Cross-sectional study530 participantsEnergy forVitamin D
  8. Fatigue and Vitamin D Status in Frail Elderly with and without Cancer, and Healthy Controls of Different Ages: Results from the IMAGE Study.
    Dahlén E; Hedman C; Mily A; Alisjahbana A; Spulber G; Holmström-Edstedt J; Bergman P; Buggert M; Björkhem-Bergman L · Gerontology · 2025
    Cohort study273 participantsEnergy forVitamin D
  9. Role of vitamin D as adjuvant therapy on multiple sclerosis: an updated systematic review and meta-analysis of randomized controlled trials.
    Serag I; Abouzid M; Alsaadany KR; Hendawy M; Ali HT; Yaseen Y; Moawad MHED · European journal of medical research · 2025
    Meta-analysis1,903 participants21 studies pooledEnergy forVitamin D
  10. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  11. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  12. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  13. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  14. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  15. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  16. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  17. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  18. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  19. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  20. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  21. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  22. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  23. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  24. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  25. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  26. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  27. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  28. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  29. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  30. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  31. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  32. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  33. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  34. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  35. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  36. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D