Healthy Mood 5-HTP Elite 100 mg Natural Raspberry Flavor

Healthy Mood 5-HTP Elite 100 mg Natural Raspberry Flavor

Carlson4.7 (435 ratings)
Format:Tablet Quantity: 120 Tablet(s) · 60 servings
Goals
$27.63 $0.46 per serving
iHerbLowest$27.63Vitacost$27.63Pure Formulas$27.63Amazon$27.63Walmart$29.84

About this product

A standard 100 mg 5-HTP serving gives the formula a clear and focused role in serotonin-related mood and sleep support. The amount matches the practical middle ground represented in the supplied goal analyses without pushing into a high-strength serving.

Griffonia simplicifolia is identified as the source, although no active standardization percentage is supplied. The tablet(s) format is convenient, but it does not add a disclosed release or absorption feature.

Vitamin B6 supports relevant metabolism, though it does not remove the narrow pathway coverage or interaction concerns of 5-HTP. Value is reasonable for a focused 5-HTP serving. It best fits adults seeking a straightforward middle-dose option for mood or sleep support.

Who is it for
  • Adults seeking a standard 5-HTP amount
  • People focused on mood or sleep support
  • Users who prefer a simple capsule or tablet routine
Best for
  • Focused serotonin-pathway mood support
  • Indirect sleep support through serotonin and melatonin pathways
  • Stress accompanied by low mood or disrupted sleep

Pros

  • Clearly discloses 100 mg of 5-HTP
  • Tablet(s) format is easy to use
  • Names Griffonia simplicifolia as the botanical source
  • Includes a disclosed form and amount of vitamin B6
  • Focused formula is easy to assess

Cons

  • No 5-HTP standardization percentage is provided
  • No controlled-release or enteric delivery feature is disclosed
  • Single-pathway formula offers limited support beyond serotonin production

Warnings

  • Do not combine 5-HTP with SSRIs, SNRIs, MAO inhibitors, tramadol, or other serotonin-raising medicines because serotonin toxicity can occur.
  • The 100 mg 5-HTP serving may cause nausea or digestive upset.
  • Avoid stacking it with other serotonin-focused supplements such as tryptophan or SAMe unless a qualified clinician has reviewed the combination.

Product analysis

78 out of 100
100 mg of 5-HTP provides standard serotonin-pathway support in a convenient format. The named Griffonia source helps, but missing standardization limits quality detail.

AI assessment of the formula, label and price. How scoring works

Nutrient quality85

The Griffonia source and active pyridoxal 5-phosphate are useful, though extract standardization is absent. The 5-HTP amount matches a common standard serving, while missing extract standardization limits source-potency confidence.

Ingredient transparency81

Every listed active amount is disclosed, and no proprietary blend hides dosing. Complete directions, inactive ingredients, and some source or standardization details remain unavailable.

Customer satisfaction67

The aggregate rating is favorable, and the large review count supports confidence. No detailed feedback is supplied, so repeated complaints and purpose fit cannot be judged.

Value for money75

A standard 5-HTP amount and two B6 forms provide reasonable formula quality. The tablet serving and less favorable economics limit competitiveness.

Format
Tablet
Container
120 Tablet(s)
Per serving
$0.46
Also available
Chewable 5-HTP 100 mg Natural Citrus Flavor5-HTP 100 mg • 90 Tablet(s) • 90 servings$14.56
Customer rating
4.7 · 435 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
Highest effect
A Ingredient FitC- PathwaysA EvidenceA+ Formulation Logic
Vitamin B6 · 2 mg5-HTP · 100 mg

Whether 5-HTP improves everyday mood remains unclear. It is a precursor to serotonin, but making a substance involved in mood is different from showing that taking the ingredient improves emotional well-being. Its presence therefore doesn't provide a reliable expectation of a mood lift or an antidepressant effect.

How this product is rated for Mood Support

Ingredient fit95

The mood benefit of the nutrients depends on low levels contributing to symptoms.
Goal fit
The mood benefit of the nutrients depends on low levels contributing to symptoms.
Dose adequacy
Declared serving amounts include 5-HTP 100 mg. These are serving amounts, not an assumed daily intake.

Pathways59

Nutrient and botanical roles in mood-related processes do not by themselves demonstrate an improvement in how you feel.
Depth
The most represented biological role is monoamine signalling; this describes a mechanism, not a guaranteed change in mood.
Breadth
The main represented roles are monoamine signalling. These do not imply separate or additive emotional benefits.

Evidence94

The mood benefit of the nutrients depends on low levels contributing to symptoms.
Evidence strength
The mood benefit of the nutrients depends on low levels contributing to symptoms.
Studied preparation
The identified forms permit a comparison with the relevant ingredient preparations, without guaranteeing the same benefit for every person.

Formulation logic100

No particular ingredient conflict is identified.
Partner coverage
No missing required partner is identified for the relevant ingredients.
Conflicts
No particular ingredient conflict is identified.
Effective doses
5-HTP 100 mg per serving are declared; comparison amounts don't establish a minimum effective dose.
Study evidence
5-HTP Supportive 9 studies
Vitamin B6 Supportive 19 studies
Sleep Support
Sleep Support
Impact
Moderate effect
A Ingredient FitC PathwaysC- EvidenceA+ Formulation Logic

5-HTP may offer limited sleep support for some people with poor sleep, but a benefit for everyone isn't clear. Its possible role in the serotonin-to-melatonin route is the main reason it relates to sleep.

Vitamin B6 helps normal metabolism, but that role doesn't establish a sleep benefit. The small amount listed is unlikely to add much here.

How this product is rated for Sleep Support

Ingredient fit95

5-HTP leads this focused formula; the small B6 amount adds little sleep-specific support.
Goal fit
Only 5-HTP has a clear sleep-related role among the listed actives.
Dose adequacy
The 5-HTP amount supports a possible sleep role; the small B6 amount contributes little.

Pathways60

The blend targets the serotonin-to-melatonin precursor route alone, with no separate timing or calming route.
Depth
5-HTP has a possible role in the serotonin-to-melatonin route, but the other sleep routes are not represented.
Breadth
Only the precursor route receives support, leaving sleep timing and calming uncovered.

Evidence58

5-HTP's sleep role remains limited and population-specific, so a broader benefit isn't established.
Evidence strength
5-HTP's sleep role is less established than the strongest sleep-timing ingredients.
Studied preparation
The 5-HTP form and amount fit its available sleep role.

Formulation logic100

5-HTP can play its possible role on its own; the small B6 amount adds little sleep support.
Partner coverage
5-HTP can play its possible role on its own; B6 is not needed for it to do so.
Conflicts
No listed ingredient is identified as working against sleep at bedtime.
Effective doses
5-HTP reaches a meaningful amount for its possible role; B6 does not.
Study evidence
5-HTP Supportive 1 study
Vitamin B6 Disputed 7 studies
Stress Relief
Stress Relief
Impact
Moderate effect
A Ingredient FitD PathwaysC- EvidenceA+ Formulation Logic
Vitamin B6 · 2 mg

5-HTP may help with anxiety or stress-related symptoms in some circumstances. Whether that translates into relief from everyday stress remains uncertain, because its useful effects depend on the situation. The 100 mg serving matches the saved middle comparison amount, but that isn't a guarantee of benefit. The small amount of vitamin B6 doesn't provide a clear reason to expect the combination to work better.

How this product is rated for Stress Relief

Ingredient fit95

5-HTP provide the relevant connection to stress. 5-HTP supplies 100 mg per serving, matching the middle comparison amount; vitamin B6 supplies 2 mg.
Goal fit
5-HTP relate to stress, with the qualifications described for their individual effects.
Dose adequacy
5-HTP supplies 100 mg per serving, matching the middle comparison amount; vitamin B6 supplies 2 mg.

Pathways46

The ingredient connections center on mood-related functions. These roles don't indicate how much relief an individual will feel.
Depth
The strongest ingredient connection is to mood-related functions; this does not predict an individual's response.
Breadth
The connections are concentrated in a limited set of roles, rather than demonstrating broad relief from stress.

Evidence56

5-HTP has a conditional connection to anxiety and stress-related symptoms, with uncertain everyday applicability.
Evidence strength
5-HTP may help selected anxiety or stress-related symptoms; everyday applicability remains conditional.
Studied preparation
The identified preparations have relevant support, while the practical limits of each ingredient still apply.

Formulation logic100

The relevant ingredients do not require an additional partner for their individual roles. No particular ingredient conflict is identified.
Partner coverage
The relevant ingredients can act individually without an additional required partner.
Conflicts
No particular conflict among the declared ingredients is identified.
Effective doses
The relevant ingredient amounts are known; their presence does not guarantee stress relief.
Study evidence
5-HTP Supportive 18 studies
Vitamin B6 Supportive 10 studies
Weight Loss
Weight Loss
Impact
Moderate effect
C Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 5 studies

Ingredients

IngredientAmount per servingScore
Vitamin B-6 (Pyridoxine Hydrochloride, Pyridoxyl-5-Phosphate)
 2 mg
5-HTP (Griffonia simplicifolia)
 100 mg 80
Gluten Free Adults 18–50 Women
Report overview
5-HTP (Griffonia simplicifolia) · 100 mg OverallScore80
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
Healthy Mood 5-HTP Elite 100 mg Natural Raspberry Flavor names Griffonia simplicifolia, but does not state a standardization percentage. It provides 100 mg per serving, matching the supplied reference amount. A specific warning about SSRIs, antidepressants, or serotonin-modulating medicines is listed. The cost per 100 mg is moderate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

It identifies Griffonia simplicifolia as the botanical source, but does not give a standardization percentage.
Botanical Source & Standardization
It names Griffonia simplicifolia as the botanical source, but no standardization percentage is given.

Dose, Safety & Label Transparency100

It provides the 100 mg reference amount per serving. A specific warning about SSRIs, antidepressants, or serotonin-modulating medicines is listed.
Dosage Potency & Range
It provides 100 mg per serving, matching the supplied reference amount.
Safety Warnings & Label Clarity
A specific warning about SSRIs, antidepressants, or serotonin-modulating medicines is listed.

Value60

The cost per 100 mg is moderate.
Price per 100mg 5-HTP
The cost per 100 mg is moderate.
View ingredientView products
Loading alternative details
85 Performance

5-HTP 100 mg

NOW
Clearer botanical sourcing makes this a stronger quality alternative. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP 100 mg Extra Strength

Swanson
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
84 Budget

5-HTP 50 mg

NOW
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving offers a more cautious starting option than the original’s 100 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
85 Budget

5-HTP 100 mg

Doctor's Best
The lower recurring cost makes this a more economical eligible choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
82 Budget

5-HTP 50 mg

Swanson Premium Brand
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving offers a more cautious starting option than the original’s 100 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP 200mg

Best Naturals
Focused 5-HTP dosing and a lower recurring cost create a favorable quality-to-cost balance. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP with Vitamin B6 & Vitamin C

Lake Avenue Nutrition
Focused 5-HTP dosing and a lower recurring cost create a favorable quality-to-cost balance. The active amount is disclosed, but botanical-source detail remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
82 Value

5-HTP 200 mg Maximum Strength

Swanson
Focused 5-HTP dosing and a lower recurring cost create a favorable quality-to-cost balance. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
    Li S; Sutanto CN; Xia X; Kim JE · Nutrients · 2025
    Randomized trial30 participantsMood Support for5-HTP
  2. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
    Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
    Randomized trial70 participantsMood Support for5-HTP
  3. Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
    Javelle F; Lampit A; Bloch W; Häussermann P; Johnson SL; Zimmer P · Nutrition reviews · 2020
    Meta-analysis13 studies pooledMood Support for5-HTP
  4. Tryptophan and 5-hydroxytryptophan for depression.
    Shaw K; Turner J; Del Mar C · The Cochrane database of systematic reviews · 2002
    Systematic review64 participants2 studies pooledMood Support for5-HTP
  5. Symptomatic treatment of interferon-α-induced depression in hepatitis C: a systematic review.
    Baraldi S; Hepgul N; Mondelli V; Pariante CM · Journal of clinical psychopharmacology · 2012
    Systematic review64 studies pooledMood Support for5-HTP
  6. The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
    Sutanto CN; Xia X; Heng CW; Tan YS; Lee DPS; Fam J; Kim JE · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trial30 participantsSleep Support for5-HTP
  7. Serotonin precursors in the treatment of depression.
    van Praag HM · Advances in biochemical psychopharmacology · 1982
    Narrative reviewMood Support for5-HTP
  8. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
    Aliño JJ; Gutierrez JL; Iglesias ML · International pharmacopsychiatry · 1976
    Non-randomized trial30 participantsMood Support for5-HTP
  9. Measurement of 5-hydroxyindole compounds during L-5-HTP treatment in depressed patients.
    Takahashi S; Takahashi R; Masumura I; Miike A · Folia psychiatrica et neurologica japonica · 1977
    Single-arm trial14 participantsMood Support for5-HTP
  10. Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.
    Truyens M; Lobatón T; Ferrante M; Bossuyt P; Vermeire S; Pouillon L; Dewint P; Cremer A; Peeters H; Lambrecht G; Louis E; Rahier JF; Dewit O; Muls V; Holvoet T; Vandermeulen L; Peeters A; Gonzales GB; Bos S; Laukens D; De Vos M · Gastroenterology · 2022
    Randomized trial166 participantsMood Support for5-HTP
  11. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  12. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support Stress Relief forVitamin B6
  13. Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
    Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
    Cross-sectional study24,683 participantsMood Support forVitamin B6
  14. Associations of dietary B vitamins intakes with depression in adults.
    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
    Observational study17,732 participantsMood Support forVitamin B6
  15. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
    Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
    Cohort study88 participantsMood Support forVitamin B6
  16. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  17. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  18. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  19. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  20. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6
  21. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
    Kahn RS; Westenberg HG; Verhoeven WM; Gispen-de Wied CC; Kamerbeek WD · International clinical psychopharmacology · 1987
    Randomized trial45 participantsStress Relief for5-HTP
  22. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
    Schruers K; van Diest R; Overbeek T; Griez E · Psychiatry research · 2003
    Randomized trial48 participantsStress Relief for5-HTP
  23. Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
    Smarius LJ; Jacobs GE; Hoeberechts-Lefrandt DH; de Kam ML; van der Post JP; de Rijk R; van Pelt J; Schoemaker RC; Zitman FG; van Gerven JM; Gijsman HJ · Journal of psychopharmacology (Oxford, England) · 2008
    Randomized trialStress Relief for5-HTP
  24. Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Jacobs GE; Kamerling IM; de Kam ML; Derijk RH; van Pelt J; Zitman FG; van Gerven JM · Journal of psychopharmacology (Oxford, England) · 2010
    Randomized trialStress Relief for5-HTP
  25. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
    Emanuele E; Bertona M; Minoretti P; Geroldi D · Neuro endocrinology letters · 2011
    Single-arm trial15 participantsStress Relief for5-HTP
  26. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forVitamin B6
  27. RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
    Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
    Randomized trial128 participantsStress Relief forVitamin B6
  28. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
    Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
    Randomized trial264 participantsStress Relief forVitamin B6
  29. Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
    Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
    Cross-sectional study447 participantsStress Relief forVitamin B6
  30. The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT.
    Evans C; Mekhail V; Curtis J; Czartoryski P; Kaminski J; Ellerbroek A; Bustillo E; Jiannine L; Santana JC; Antonio J · Journal of dietary supplements · 2023
    Randomized trial48 participantsWeight Loss for5-HTP
  31. Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients.
    Cangiano C; Laviano A; Del Ben M; Preziosa I; Angelico F; Cascino A; Rossi-Fanelli F · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 1998
    Randomized trial25 participantsWeight Loss for5-HTP
  32. The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects.
    Ceci F; Cangiano C; Cairella M; Cascino A; Del Ben M; Muscaritoli M; Sibilia L; Rossi Fanelli F · Journal of neural transmission · 1989
    Clinical trial19 participantsWeight Loss for5-HTP
  33. Serotonergic drugs : effects on appetite expression and use for the treatment of obesity.
    Halford JC; Harrold JA; Boyland EJ; Lawton CL; Blundell JE · Drugs · 2007
    Narrative reviewWeight Loss for5-HTP
  34. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan.
    Cangiano C; Ceci F; Cascino A; Del Ben M; Laviano A; Muscaritoli M; Antonucci F; Rossi-Fanelli F · The American journal of clinical nutrition · 1992
    Randomized trial20 participantsWeight Loss for5-HTP