B-6 B-12 Methyl Folate Mixed Berry
KAL
B-6 B-12 Methyl Folate Mixed Berry
4.9
★ ★ ★ ★ ★
(2056 ratings)
Folate 400 mcg
Vitamin B12 2500 mcg
Score 90.0
A high-potency B12 and Folate supplement with excellent bioavailable forms, offering strong support for energy and brain health at a good value.
Quantity: 60 Tablet(s)Servings size: 1 Micro Tablet(s) (60 servings)
Selected goals:
Other goals:
General Health
Brain Health
Mood Support
Heart Health
Energy
leaderboard Score 90.0
A high-potency B12 and Folate supplement with excellent bioavailable forms, offering strong support for energy and brain health at a good value.
insights Analysis
This supplement features 2500mcg of Methylcobalamin, which is a potent dose ideal for energy, nerve health, and cognitive support, particularly beneficial for those with significant deficiencies. The inclusion of 400mcg of 5-MTHF (active folate) addresses the needs of individuals who may have difficulty converting synthetic Folic Acid, enhancing its overall effectiveness. Online reviews frequently praise the product's effectiveness and taste. At $0.28 per serving, it balances high-quality, active ingredients with a reasonable price, placing it among the top options in its category.
- Contains high dosage of highly bioavailable Methylcobalamin.
- Utilizes the active and easily absorbable 5-MTHF (folate).
- Excellent for individuals with MTHFR gene variations or absorption issues.
- Good balance of quality ingredients and price.
- Price per serving is higher than very basic or synthetic-form alternatives.
$16.89($0.28 per serving)
 Vitacost | $ 16.89 | |
 iHerb | $ 16.89 |
bolt Effectiveness for goals
Yes, adequate folate intake, particularly before and during early pregnancy, is highly effective. It is crucial for reducing the risk of neural tube defects in the developing fetus. Health organizations recommend daily supplementation for women of childbearing age.
Both are essential B vitamins vital for cell growth, DNA synthesis, and the formation of red blood cells. They also play crucial roles in nervous system function and energy metabolism. Their combined action supports overall cellular health and genetic processes.
Vitamin B12 is essential for energy metabolism, but supplementing typically boosts energy only if a deficiency is present. Individuals without a deficiency usually do not experience a significant increase in energy. Consulting a healthcare provider can determine if a deficiency is present.
Yes, Vitamin B12 plays a critical role in the maintenance of myelin, the protective sheath surrounding nerves. A deficiency can lead to nerve damage and various neurological symptoms. Adequate intake is necessary for proper nerve function.
Individuals at risk of deficiency, such as strict vegetarians and vegans, older adults, and those with certain digestive disorders (e.g., pernicious anemia, Crohn's disease), may benefit. These groups may have impaired absorption or insufficient dietary intake. A healthcare professional can assess individual needs.
schedule Dosage, timing & forms
Yes, Vitamin B12 and Folate supplements can typically be taken together. They often work synergistically in the body, particularly in metabolic pathways like the methylation cycle and red blood cell formation. Many multivitamin and B-complex supplements are formulated to include both nutrients.
The recommended daily intake of Folic Acid for individuals who are pregnant or planning pregnancy is 400-800 micrograms (mcg). This dosage is crucial to help prevent neural tube defects in the developing fetus. It is commonly advised to begin supplementation at least one month before conception and continue through early pregnancy.
The recommended dietary allowance (RDA) for Vitamin B12 in adults is 2.4 micrograms (mcg) per day. Pregnant individuals require 2.6 mcg, and breastfeeding individuals need 2.8 mcg daily. These recommendations are designed to meet the nutritional needs of most healthy people.
The recommended dietary allowance (RDA) for Folate in adults is 400 micrograms (mcg) of dietary folate equivalents (DFEs) per day. This intake helps prevent deficiency and supports essential bodily functions. Higher requirements are typically advised for individuals who are pregnant or planning pregnancy.
Yes, high doses of supplemental Folate, especially folic acid, can mask the macrocytic anemia that is a symptom of Vitamin B12 deficiency. This can delay the diagnosis and treatment of B12 deficiency, potentially leading to irreversible neurological damage. For this reason, it is important to rule out Vitamin B12 deficiency before starting high-dose folate supplementation.
health_and_safety Safety & interactions
Yes, high doses of folic acid (synthetic folate) can mask the macrocytic anemia associated with vitamin B12 deficiency. While folic acid can resolve the anemia, it does not address the neurological damage that can progress due to an uncorrected B12 deficiency. It is important to rule out B12 deficiency before supplementing with high doses of folic acid.
Yes, Vitamin B12 and Folate can generally be taken together safely, and they often work synergistically in the body. They are both crucial for DNA synthesis and red blood cell formation. This combination is commonly found in B-complex supplements and prenatal vitamins.
Vitamin B12 is generally considered safe, even at high doses, due to its water-soluble nature. Mild side effects such as headache, nausea, or diarrhea are rare. Allergic reactions, while extremely uncommon, can occur in sensitive individuals.
Vitamin B12 has a very low potential for toxicity. No tolerable upper intake level (UL) has been established due to the lack of adverse effects observed even at very high intakes. Excess is typically excreted in the urine.
Folate and folic acid supplements are generally well-tolerated. High doses may rarely cause mild symptoms like nausea, bloating, or trouble sleeping. Allergic reactions are uncommon.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B-6 | 3 mg |
Folate | 400 mcg |
Vitamin B12 | 2500 mcg |
Categories
Vitamin B12 95.0
The product features a high dosage of Methylcobalamin, which is the most preferred and bioavailable form of Vitamin B12, ensuring excellent absorption and direct utilization by the body. This is a top-tier offering for B12.
Folate 90.0
Folate is provided as 5-MTHF, an active and highly absorbable form that bypasses the need for metabolic conversion, making it superior to synthetic Folic Acid for optimal cellular function. This is a very strong offering for folate.
Goals
Energy 95.0
The high dose of Methylcobalamin, combined with active folate, is extremely effective for energy production and combating fatigue by optimizing cellular metabolic pathways. This makes it a top-tier choice for boosting energy.
Brain Health 95.0
Both Methylcobalamin and 5-MTHF are crucial for neurological function, neurotransmitter synthesis, and myelin sheaths. Their active forms ensure maximum support for overall brain health, as recommended by brain health experts.
Cognitive Support 95.0
The potent Methylcobalamin and active 5-MTHF are ideal for enhancing cognitive functions, including memory, focus, and mental clarity, by optimizing neural pathways and reducing homocysteine levels. It is a strong choice for cognitive support.
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