Product Image

Core Daily 1 for Men 50+

Country Life
4.7
★ ★ ★ ★ ★
(802 ratings)
Manganese 2 mg
Phosphorus 50 mg
Biotin 300 mcg
Vitamin B5 26 mg
Choline 12 mg
Molybdenum 25 mcg
Selenium 70 mcg
Product Image
Score65
One tablet per serving is a useful strength, but undefined men’s health blend is the main trade-off.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
General Health
Immunity
Hair Health
Nail Health

Score 65

One tablet per serving is a useful strength, but undefined men’s health blend is the main trade-off.
How scoring works
$25.29($0.42 per serving)
iHerb
$ 31.99
Pure Formulas
$ 31.99
Amazon
$ 25.29
Vitacost
$ 31.99
Report prices

Analysis

Active forms of several B vitamins, natural vitamin E, vitamin D3, minerals, and phosphatidylserine-DHA provide broad one-tablet coverage for older men. The named forms and amounts show where the formula provides its clearest nutritional value.

Repeated source entries and undefined men’s, enzyme, and probiotic blends make the formula hard to interpret, while calcium, magnesium, choline, and DHA lack meaningful depth. Those limitations matter when comparing it with simpler or more transparent alternatives.

The one-tablet format is convenient for an older man who wants broad coverage and accepts a complex formula. A simpler multivitamin with transparent totals would be easier to assess and less likely to include token extras.

Who is it for
  • Men over 50 seeking one-tablet coverage
  • Users who want a broad formula rather than high mineral amounts
Best for
  • General micronutrient coverage for older men
  • Convenient once-daily use

Pros

  • One tablet per serving
  • Includes active B-vitamin forms
  • Provides vitamin D3 and natural vitamin E
  • Includes several trace minerals

Cons

  • Undefined men’s health blend
  • Enzyme and probiotic blend lacks useful detail
  • Low choline and magnesium
  • Repeated entries obscure totals

Warnings

  • Vitamin K can interfere with warfarin dosing and should remain consistent under prescriber guidance.
  • Contains fish and soy-derived ingredients, which may not suit people with those allergies.

Nutrient quality

75 High impact

Active B-vitamin forms, natural vitamin E, citrate minerals, and methylfolate provide a strong nutrient base. Modest minerals, tiny choline, and broad specialty blends reduce depth.

Ingredient transparency

54 Moderate impact

Many nutrient amounts and forms are supplied, but health and enzyme blends are incompletely described. Repeated nutrient entries and missing excipients make the exact formulation difficult to verify.

Customer satisfaction

68 High impact

The supplied average rating is strong and the review base is substantial. No review text is available to assess recurring complaints or experiences tied to the intended use.

Value for money

66 High impact

Many good vitamin forms and a moderate serving cost provide sound basic value. Hidden blends and small specialty doses weaken the premium positioning.

Report analysis

Goals

General Health
Daily Energy Vitality
General Health
Impact
High effect
A- Goal FitC+ Strength of SupportB CoverageB- Formula Quality
Folate · 200 mcg DFEVitamin B12 · 100 mcgVitamin D · 10 mcgMagnesium · 50 mgVitamin K · 81 mcgSelenium · 70 mcgZinc · 5 mgVitamin C · 100 mg

Broad vitamins and minerals directly support nutritional maintenance for older men. The essential nutrients have established physiological roles, while specialty blend benefits are less certain from the available detail.

Many vitamins and trace minerals meet maintenance needs, but vitamin D, magnesium, calcium, and folate remain modest. Active folate and coenzyme B-vitamin forms add quality, while magnesium oxide, sodium selenate, K1, and mixed B12 forms reduce it.

Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin B12 Adverse 66 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Immunity
Immunity
Impact
High effect
B Goal FitC+ Strength of SupportB- CoverageC Formula Quality
Magnesium · 50 mgVitamin C · 100 mgZinc · 5 mgVitamin A · 750 mcgVitamin D · 10 mcgSelenium · 70 mcg

Vitamins A, C, D, and E plus selenium provide several relevant immune nutrients within a broad daily formula. The product supports baseline nutritional readiness more than a focused acute immune response.

Many vitamin forms are thoughtful, but sodium selenate is less retained and some blends are incompletely disclosed. Numerous repeated forms and specialty blends make the formula crowded relative to its immune-specific depth.

Study evidence
Selenium Mixed 37 studies
Zinc Supportive 73 studies
Hair Health
Hair Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportC- CoverageD Formula Quality
Biotin · 300 mcgVitamin D · 10 mcgZinc · 5 mgVitamin C · 100 mg

The mature men's multivitamin has limited but broad nutritional relevance to hair. D-biotin, selenium, vitamin D3, vitamin C, active folate, and mixed B12 cover several basic needs.

Zinc and copper are low, iron is absent, and most specialty blends do not support hair directly. It provides nutritional coverage rather than a focused hair-growth strategy.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Folate Mixed 15 studies
Selenium Disputed 7 studies
Vitamin B12 Disputed 17 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies
Nail Health
Healthy Nail Growth
Nail Health
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC- CoverageD- Formula Quality
Biotin · 300 mcg

D-biotin, zinc or iron, vitamin C, and B vitamins provide several nutritional cofactors for normal nail growth. The biotin amount is suited to basic nutrition rather than focused support for brittle nails.

Active folate and several organic mineral forms improve quality, but the formula supplies no collagen, cysteine, or quantified silica. Broad health blends and numerous unrelated nutrients make it a general multivitamin rather than a dedicated nail product.

Study evidence
Biotin Supportive 8 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 750 mcg
Vitamin C (Acerola berry extract, Amla extract, Calcium Ascorbate)
 100 mg
Vitamin D (Vitamin D3)
 10 mcg
Vitamin E (D-Alpha-Tocopheryl Acid Succinate)
 33.5 mg
Vitamin K (Phytonadione)
 81 mcg
Thiamin (Thiamine Cocarboxylase Chloride, Thiamine Hydrochloride)
 5 mg
Riboflavin (Riboflavin 5-Phosphate)
 5 mg
Niacin (Inositol Hexanicotinate)
 20 mg
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
 5 mg
Folate ((6S)-5-Methyltetrahydrofolate-Glucosamine Salt)
 200 mcg DFE
Vitamin B12 (Cyanocobalamin, Methylcobalamin)
 100 mcg
Biotin (D-Biotin)
 300 mcg
Pantothenic Acid (Calcium D-Pantothenate, Pantethine)
 26 mg
Calcium (Calcium Ascorbate, Calcium D-Pantothenate, Calcium Fructoborate, Calcium Hydroxyapatite)
 107 mg
Phosphorus (Calcium Hydroxyapatite)
 50 mg
Magnesium (Magnesium Citrate, Magnesium Oxide)
 50 mg
Zinc (Zinc Citrate)
 5 mg
Selenium (Sodium Selenate)
 70 mcg
Copper (Copper Amino Acid Chelate)
 0.25 mg
Manganese (Manganese Amino Acid Chelate)
 2 mg
Chromium (Chromium Picolinate)
 50 mcg
Molybdenum (Molybdenum Amino Acid Chelate)
 25 mcg
Potassium (Potassium Citrate)
 10 mg
Choline (Choline Bitartrate)
 12 mg
Men's Health Blend
208 mg
Betaine (Betaine Hydrochloride)
 76 mg
Sharp-PS Gold Conjugated PS-DHA (Soy Lecithin, Docosahexaenoic Acid, Fish extracts, PS)
 56 mg
Inositol (Inositol Hexanicotinate)
 54 mg
Citrus Bioflavonoid Complex (Grapefruit Bioflavonoid, Lemon Bioflavonoid, Orange Bioflavonoid)
 25 mg
Enzyme and Probiotic Blend
0 NP
Men 50+ Gluten Free Dairy Free
Report overview
Manganese (Manganese Amino Acid Chelate) · 2 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

Manganese amino acid chelate supplies a high-quality chelated form with strong absorption potential. The clearly disclosed 2 mg amount better supports nutritional maintenance than targeted bone-matrix support. A favorable serving cost supports good everyday value.

View ingredientView products
Phosphorus (Calcium Hydroxyapatite) · 50 mg OverallScore83
A+ Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyA+ Value

Calcium hydroxyapatite provides a bone-like phosphorus source with strong biological relevance. The phosphorus amount is modest and may contribute less than a targeted standalone supplement. A single-tablet serving and favorable value make it easy to use.

View ingredientView products
Biotin (D-Biotin) · 300 mcg OverallScore63
A Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

Explicit d-biotin confirms the biologically active isomer. The 300 mcg amount is closer to basic nutrition than targeted hair or nail support. The tablet is a conventional delivery format, while the many co-factors support a neutral value assessment.

View ingredientView products
Loading alternative details
82 Performance

Multi for Men

MegaFood
Active B vitamins, chelated minerals, vitamin K2, and meaningful choline create a stronger men's multivitamin foundation. Zinc is high relative to copper and vitamin K can affect warfarin management, so long-term suitability still needs review.
72 Performance

PureGenomics Multivitamin

Pure Encapsulations
Multiple active B12 forms, methylfolate, vitamin K2, natural vitamin E, and chelated minerals provide substantially better form quality. High folate and combined B12 amounts plus duplicate entries need clarification, and the serving cost is higher.
71 Performance

Core Daily 1 for Women

Country Life
Active B vitamins, natural vitamin E, magnesium citrate, and chelated minerals improve several form-quality details. The women-specific balance and hidden specialty blend make it less appropriate for some men, while choline remains modest.
73 Budget

Core Daily 1 for Men

Country Life
A lower serving cost retains active B vitamins, natural vitamin E, vitamin K, and chelated trace minerals in a broad men's formula. Hidden men's-health and enzyme-probiotic blends remain, while calcium and magnesium are modest.
72 Budget

Raw One For Men

Garden of Life Vitamin Code
A lower-cost single capsule provides broad maintenance coverage with several useful nutrient forms. Small vague blends and a zero-value enzyme entry reduce clarity, and vitamin K requires stable intake for people using warfarin.
79 Budget

Sublingual Liquid B-12 2000 mcg with B-Complex

Solgar
A much lower serving cost provides a broad liquid B-complex for energy-related nutrient support. It is not a full multivitamin, and cyanocobalamin, pyridoxine, and unspecified folate or biotin forms are less refined than the original's active forms.
78 Value

Men Over 55 One Daily

MegaFood
High-quality nutrient forms and balanced daily amounts provide a clearer maintenance formula at comparable serving value. A small phenolic blend and incomplete inactive-ingredient details limit transparency, while vitamin K requires consistent intake with warfarin.
62 Value

BalanceBlend

Fairhaven Health
Meaningful micronutrients provide broad coverage at a moderate serving cost. A large proprietary blend still prevents ingredient-level assessment, so value improves only modestly over the original's hidden blends.
64 Value

Everyday Multivitamin without A & D

Kirkman
A long supply and several active or chelated forms offer reasonable value for users intentionally avoiding vitamins A and D. Low calcium, magnesium, and choline plus a hidden amino acid blend make it less complete than the original.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  6. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  7. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  8. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  9. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  10. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  11. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  12. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  13. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  14. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  15. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  16. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  17. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  18. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  19. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  20. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  21. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  22. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  23. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  24. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  25. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  26. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  27. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledGeneral Health forVitamin K
  28. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  29. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  30. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  31. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health forBiotin
  32. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  33. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  34. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  35. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  36. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  37. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  38. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  39. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  40. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  41. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  42. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  43. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  44. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  45. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  46. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  47. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  48. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  49. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  50. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  51. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  52. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  53. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  54. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  55. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  56. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  57. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  58. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  59. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  60. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  61. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  62. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  63. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  64. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  65. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  66. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  67. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  68. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  69. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  70. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  71. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  72. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  73. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  74. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  75. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  76. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forZinc
  77. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C